• Journal of Korean Neurosurgical Society
• /
• 제42권2호
• /
• pp.118-124
• /
• 2007

Objective : Adipose tissue is derived from the embryonic mesoderm and contains a heterogenous stromal cell population. Authors have tried to verify the characteristics of stem cell of adipose derived stromal cells (ADSCs) and to investigate immunohistochemical findings after transplantation of ADSC into rat brain to evaluate survival, migration and differentiation of transplanted stromal cells. Methods : First ADSCs were isolated from human adipose tissue and induced adipose, osseous and neuronal differentiation under appropriate culture condition in vitro and examined phenotypes profile of human ADSCs in undifferentiated states using flow cytometry and immunohistochemical study. Human ADSCs were transplanted into the healthy rat brain to investigate survival, migration and differentiation after 4 weeks. Results : From human adipose tissue, adipose stem cells were harvested and subcultured for several times. The cultured ADSCs were differentiated into adipocytes, osteoctye and neuron-like cell under conditioned media. Flow cytometric analysis of undifferentiated ADSCs revealed that ADSCs were positive for CD29, CD44 and negative for CD34, CD45, CD117 and HLA-DR. Transplanted human ADSCs were found mainly in cortex adjacent to injection site and migrated from injection site at a distance of at least 1 mm along the cortex and corpus callosum. A few transplanted cells have differentiated into neuron and astrocyte. Conclusion : ADSCs were differentiated into multilineage cell lines through transdifferentiation. ADSCs were survived and migrated in xenograft without immunosuppression. Based on this data, ADSCs may be potential source of stem cells for many human disease including neurologic disorder.

• Journal of Nutrition and Health
• /
• 제23권1호
• /
• pp.25-36
• /
• 1990

This study was carried out to investigate Mg status and the relationship between dietary Mg the blood pressure in 30 healthy women, 26 to 57 year of age, living in rural area of Korea. Dietary intake of the subjects on self-selected diet were recorded. Duplicated food sample and 24-hour urine samples were collected for 3 days. Mean daily dietary Mg intake levels were determined by chemical analysis of duplicated food samples and mean daily urinary Mg excretion was measured from urine samples. Fasting serum Mg levels of each subjects was measured on the 3rd day of the survey. The results were as following: 1) The mean daily intakes of energy, protein were 1770.36㎉ and 55.55g, respectively. Carbohydrare, fat and protein supplied 77.1%, 10.4% and 12.5% of total energy intake. 2) The dietary Mg showed positive correlations with carbohydrate(P<0.05), vitamin A and vitamin B2(P<0.01), energy, Ca, P, fiber, vitamin B1 and niacin(P<0.001), but negative correlation with SBP(P<0.05). 3) The daily mean intake of Mg was 259.07$\pm$74.54mg and the urinary excretion of Mg was 75.48$\pm$33.14mg which was 29.5% of the dietary intake of Mg. And there was no significance between the dietary intake and the urinary excretion of Mg. 4) The dietary fiber showed negative correlations with SBP and DBP(P<0.05). 5) The serum and urinary concentrations of Mg were normal range and the serum Mg showed negative correlation with dietary vitamin C(P<0.05, r=-0.3655). It was concluded that the dietary Mg level of Korean rural women consuming self-selected diets was lower than that of RDA of American women but higher than that of RDA of Canadian. And the dietary intake levels of Mg and fiber, which are contained mostly in cereals and vegetables are useful to prevent hypertention.

• Journal of Nutrition and Health
• /
• 제14권4호
• /
• pp.209-219
• /
• 1981

To evaluate long-term metabolic response of free-living Korean subjects consuming local sources adequately or slightly below habitual intake. Subjects, six male medical students aged 23-25 years were free-living, but consumed diets in the metabolic unit. They were healthy as determined from medical laborarory tests. They belong to the Korean middle-class. Temperature of outdoor during study were ranged between -2 to $26^{\circ}C$, whereas the indoor were $18-22^{\circ}C$. Animal protein ranged between 25-30% of total calorie. The three meals and a vitamin supplement to meet recommendation were given daily. Three 50day periods following the design were used to test the protein-energy adequacy of the diet. Urinary nitrogen excretion was measured daily. Fecal samples were pooled for the last 5 days of each week. Nitrogen balance was computed using 5mg N/Kg skin and miscellaneous losses. Body weight was measured daily. The study was covered on 126 metabolic observations weekly. Body weight changes were relatively stable with the energy intake of 37-44Kca1/kg, and N-balances were also relatively stable, but it was influenced by physical and or mental stress somehow. It could be assumed that the mean protein and energy requirement were $190{\pm}10mg$ N/Kg with $41{\pm}2$ Kcal/kg, and the mean digestibility of protein was 81% on these subjects with the experimental conditions. The protein requirement, however, could be cut down somewhat with some limited increaing of energy intake under parameters of N-balance and maintaining body weight. It was also observed a tendency of the requirement were getting smaller with the increase of body size.

• 한국통신학회논문지
• /
• 제35권2B호
• /
• pp.191-196
• /
• 2010

흡연, 당뇨, 비만 및 스트레스 등에 의한 심장 질환이 증가됨에 따라 이로 인한 사망률이 늘어나면서 심장 질환은 현대 사회에서 조기 진단의 필요성을 제시하고 있는 실정이다. 특히 심장 질환에 대한 사람들의 무지와 무관심 때문에 발병율이 급격히 증가하고 있다. 따라서 이와 같은 심장 질환에 대한 사회적 현상을 해결하기 위해 본 논문에서는 동의보감에서 제시하고 있는 심장 상태에 대한 진단 이론을 기반으로 심장 질환의 조기 진단에 필요한 객관적 출력 변수를 설계하였다. 특히 심장 질환에 따른 발음의 부정확성을 입증하기 위해 성대의 진동 변화율을 추출하여 실험 집단간의 비교, 분석을 수행하였다. 이를 위해 본 논문에서는 표준어를 구사하는 성인 남성 중에서 심장 질환을 앓고 있는 환자들과 심장에 이상이 없는 정상인들로 피실험자 집단을 구성하고 이들의 음성을 수집하여 성대 진동의 변화율에 대한 비교, 분석을 통해 심장 질환에 대한 조기 진단 방법을 제안하였다.

• Physical Therapy Rehabilitation Science
• /
• 제4권2호
• /
• pp.108-114
• /
• 2015

Objective: The purpose of this study was to examine the effect on vital capacity (VC) and inspiratory muscle activation according to the anterior and posterior pelvic tilt positions. Design: One group pretest-posttest design. Methods: Twenty-six healthy adult men and women, age 19 to 27 years, volunteered to participate in this study. Forced vital capacity (FVC), and forced expiratory volume in 1 second ($FEV_1$) were measured by desktop spirometer in the pelvic positions during respiration, and muscle activation was recorded from sternocleidomastoid, upper trapezius, external intercostal, rectus abdominis, and external oblique muscles by surface electromyography (EMG) at the same time. EMG values were normalized by maximum muscle contractions (% maximum voluntary isometric contraction). Subjects were to breathe in as much air as possible and then exhale as quickly as possible in both anterior and posterior pelvic tilt positions. To measure lung capacity, inspiration was measured for 5 seconds and expiration was measured for 7 seconds with data collection taken place during the middle three seconds. Lung capacities were measured in each position three times. Results: For the results of this study, there was a significant increase in both FVC and $FEV_1$ values during the anterior pelvic tilting compared to the posterior pelvic tilting posture (p<0.05). The sternocleidomastoid, upper trapezius muscle, rectus abdominus and external oblique muscle activation was significantly increased during anterior pelvic tilt compared to the posterior pelvic tilt position (p<0.05). Conclusions: These findings suggest that pelvic anterior tilt position could be more effective for vital capacity and respiratory muscles activation during respiration.

• 복식문화연구
• /
• 제13권3호
• /
• pp.406-413
• /
• 2005

This study performed the evaluation of skin temperature, heart rate, temperature and relative humidity of microclimate, and subjective sensation, such as thermal sensation, wet sensation and comfort sensation to estimate physiological responses of the human body and its comfortable feeling to the vitamin E fabric. Experiments were performed on the five healthy adult women whose average age was 21, at climate chamber in which temperature, relative humidity and air current were set up below $30{\pm}\;1^{\circ}C$, $50{\pm}\;15\%$ and 0.2m/s, respectively. Two kinds of clothes were used for experiments: unfinished sports clothes, with the same form and the same size, of short-sleeved knit shirt and long trousers made with $100\%$ cotton, and finished sports clothes printed with the vitamin E solution of the level of $0.88\%$. Exercises of walking (about 105 steps/minute) with the exercise intensity of 2.5 were performed for 20 minutes using treadmill. In result, the study showed significant difference (p<0.01) in average skin temperature between unfinished and finished sport clothes, and represented higher value with having unfinished sport clothes in wear than with finished one. The study also showed significant difference (p<0.01) in heart rate only during the period of exercise, and represented higher value generally with unfinished sport clothes than with finished one. There were significant differences not only in temperature of microclimate (p<0.01) but also in humidity of microclimate (p<0.05) between two sport clothes. As for the evaluation of subjective sensation, the study showed significant difference (p<0.05) in thermal sensation between the two kinds of sport clothes, significant difference in wet sensation only during the period of exercise, and significant difference (p<0.05) in comfort sensation only during the period of recovery.

• 동국한의학연구소논문집
• /
• 제6권2호
• /
• pp.135-143
• /
• 1998

산업 발달과 더불어 경제가 발전하고 있으나, 그것에 따른 매연의 증가로 인해 호흡기 질환으로 고생하고 있는 환자가 날로 늘어나고 있는 실정으로 임상에서 특히 많이 발생되는 만성 호흡기질환 중 호흡기 조직 자체에 손상을 일으킬 수 있는 질환이 많기에, 이에 소자도담강기탕이 인위적으로 호흡기 조직을 손상시킨 것에 대해 얼마나 효과가 있는지 알아보고저 본실험을 하였는 바, 방법은 흰쥐를 대상으로 $SO_2$를 흡인시킨 후 5일간, 그리고 $SO_2$ 흡입 전 10일과, 흡입 후 5일간 연속으로 소자도담강기탕을 경구투여하여 기관상피 및 전액분비세포를 관찰하여 유의한 효과를 얻었기에 보고하는 바이다.

• 한국의상디자인학회지
• /
• 제15권4호
• /
• pp.17-27
• /
• 2013

This study has the purpose to examine the effects of stone massage therapy on abdominal obesity reduction. 10 sessions for 5 weeks two times a week of stone massage therapy were offered to 43 adult females who were 40s through 70s with 27% or more of body fat and the results were analyzed. The body composition like body fat mass, fat free mass, weight and skeletal muscular mass etc and the degrees of obesity like body fat ratio abdominal fat ratio were measured and analyzed before and after stone massage therapy. The results are as follows: First, the subjects were obese body type and stone massage therapy produced positive effects with body fat mass, fat free mass, weight and BMI value slightly less than before the therapy. Second, as the average values of body fat ratio and waist hip ratio of subject were significantly different statistically before and after the therapy, stone massage therapy was found to be effective in reducing abdominal obesity. Third, as for the change of waist hip ratio, the therapy was found to be effective in reducing waist hip ratio that 40s decreased insignificantly after the therapy, and 50s and 60s significantly at p<0.05 level respectively from 0.92 to 0.90 and from 0.93 to 0.92. In conclusion, the results of this study indicated that stone massage therapy has positive effects on abdominal obesity reduction, and can contribute to healthy life and well-being culture.

• 한국전문물리치료학회지
• /
• 제2권1호
• /
• pp.44-50
• /
• 1995

The purpose of this study was to investigate which of 4 positions produced the highest action potential in the rectus femoris muscle of normal adult subjects. Testing was performed in supine with the right leg performing a simple straight leg raise with the knee fully extended. The left leg, however, was placed in 4 different positions: 1. Full support with $0^{\circ}$ flexion. 2. Flexed on the plinth with $60^{\circ}$ knee flexion and foot flat. 3. Same as N0.2 but with $90^{\circ}$ knee flexion. 4. Left leg hanging over the end of the plinth with $90^{\circ}$ knee flexion, $0^{\circ}$ hip flexion and no foot support. This study was designed to compare the level of electromyographic activity of the rectus femoris under 4 positions. Fourty-three healthy young adults performed three trials of each exercise condition in random order in the supine position. Electromyographic activity was recorded from surface electrodes. Rectus femoris action potentials in all 4 positions were significantly different. The highest action potential at the end of movement of the right leg occurred with the left leg hanging over the end of the plinth with $90^{\circ}$ knee flexion. It is therefore recommended the straight leg raising be performed with the contralateral leg flexed at $90^{\circ}$ over the end of the supporting surface to obtain a maximum rectus femoris isometric contraction.

• 한국융합학회논문지
• /
• 제6권6호
• /
• pp.195-200
• /
• 2015

본 연구는 2014년 경기 남부의 종합건강검진센터에서 30-55세의 건강한 성인 47명을 대상으로 경동맥 초음파검사와 혈액검사 그리고 체격측정을 실시하여 성별과 연령 간에 동일한 집단으로 분석되었고, 대상자의 엉덩이둘레는 연령에 따라 40대가 50대보다 높은 결과로 나타났다(p<0.05). 경동맥 초음파 검사결과에서는 30대와 50대에서 차이를 보였다(p<0.05). CIMT와 BMI, CIMT와 엉덩이둘레에서 양의 상관관계를 보였다(p<0.05). 또한 혈압에서 CIMT와 수축기혈압은 양의 상관관계를 보였다(p<0.05). 결론적으로 이번 연구에서는 경동맥 내중막 두께로 대사증후군 인자와의 상관성을 입증하였으며, 향후 질병의 진단을 위해서는 초음파를 활용한 대사증후군 인자들의 융합적 연구가 보다 질적인 질병진단을 위해서는 지속적으로 연구되어야 할 것으로 사료된다.