• 제목/요약/키워드: Health level seven

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청국장 식이 보충이 당뇨 쥐의 산화적 스트레스와 항산화 영양소 함량에 미치는 영향 (Effect of Chungkukjang supplementation on oxidative stress and antioxidant nutrients of diabetic rats induced by streptozotocin)

  • 박현숙;공현주;이언희;최은미;장정현;이명희;홍주연;황수정;정현아;양경미
    • 한국식품저장유통학회지
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    • 제22권2호
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    • pp.281-289
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    • 2015
  • 본 연구는 산화적 스트레스에 대한 당뇨병의 예방과 관리에 대한 청국장과 블랙푸드의 효과를 평가하고자 대두청국장, 약콩청국장 그리고 블랙푸드를 첨가한 약콩청국장 분말을 식이에 첨가하여 STZ로 유도된 당뇨쥐에게 7주간 급여한 후 지질과산화물 함량, 항산화 효소 및 항산화 영양소 상태를 측정하였다. 그 결과 당뇨로 인하여 혈청과 간조직 내 증가된 지질과산화물 함량은 대두 및 블랙푸드가 첨가된 약콩청국장 공급군에서 p<0.05 수준에서 유의적으로 낮았다. 항산화 효소 중에서 당뇨 유도로 혈청 내 catalase 활성은 변화 없었으나 SOD 활성은 감소되었으며, 이때 약콩청국장의 공급으로 SOD 활성이 유도되었다. 항산화 영양소 중에서 혈청 내 retinol 함량은 당뇨 유도로 낮아졌지만 약콩청국장의 공급으로 7.5배 가량의 증가 현상을 보였고, 간 조직 내 retinol과 ${\alpha}$-tocopherol 함량은 세종류의 청국장의 공급으로 높일수 있었다. 당뇨 유도로 낮아진 간 조직 내의 GSH/GSSG와 비장 조직의 anthocyanin 함량은 약콩청국장, 그리고 혈청 내 총 항산화능은 블랙푸드 청국장의 공급으로 높아진 것으로 나타났다. 이상의 결과 당뇨병이 유발되었을 때 산화적 스트레스 지표인 지질과산화물 함량은 증가된 반면에, 항산화 효소인 catalase 및 SOD 활성과 항산화 영양소인 retinol, ${\alpha}$-tocopherol, GSH/GSSG, TAC 및 anthocyanin 함량이 낮아졌다. 그러나 세종류의 청국장이 당뇨쥐의 산화적 스트레스 반응과 항산화 영양소 상태에 긍정적인 반응 효과를 보였다. 이를 기반으로 향후 당뇨병의 예방과 관리를 위한 건강 기능성 식품으로서 청국장 및 블랙푸드의 활용 방안에 대한 좀 더 많은 연구가 이루어져야 하겠다.

다환성 방향족 탄화수소 노출에 의한 DNA 산화적 손상과 Paraoxonase-1(PON1) 유전자 다형성이 폐암 발생에 미치는 영향 (Effects of Oxidative DNA Damage Induced by Polycyclic Aromatic Hydrocarbons and Genetic Polymorphism of the Paraoxonase-1 (PON1) Gene on Lung Cancer)

  • 이철호;이계영;최강현;홍윤철;김용대;강종원;김헌
    • Journal of Preventive Medicine and Public Health
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    • 제38권3호
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    • pp.345-350
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    • 2005
  • Objectives : Polycyclic aromatic hydrocarbons (PAHs), which are risk factors for lung cancer, have been reported to induce oxidative DNA damage. The paraoxonase (PON) plays a significant role in the detoxification of a variety of organophosphorous compounds, with paraoxonase-1 (PON1) being one of the endogenous free-radical scavenging systems in the human body. The aim of this case-control study was to investigate the effects of PAH exposure, oxidative stress and the Q192R polymorphism of PON1 genes, and their interactions in the carcinogenesis of lung cancer. Methods : One hundred and seventy seven lung cancer patients and 177 age- and sex-matched controls were enrolled in this study. Each subject was asked to complete a questionnaire concerning their smoking habits and environmental exposure to PAHs. The Q192R genotypes of the PON1 gene was examined, and the concentrations of urinary 1-hydroxypyrene (1-OHP), 2-naphthol and 8-hydroxydeoxyguanosine (8-OH-dG) measured. Results : Cigarette smoking was found to be a significant risk factor for lung cancer. The urinary 8-OH-dG level was higher in the patients, whereas the urinary 1-OHP and 2-naphthol levels were higher in the controls. There was a significant correlation between the urinary levels of 8-OHdG and 1-OHP in both the cases and controls. The PON1 polymorphism was associated with an increased risk of lung cancer. Individuals carrying the Q/Q genotype of the PON1 gene were found to be at higher risk of developing lung cancer. There was a significant correlation between the urinary levels of 8-OH-dG and 1-OHP in those with the PON1 Q/Q genotype. Conclusions : These results lead to the conclusion that PAHs would induce oxidative DNA damage, especially in individuals with the PON1 Q/Q genotype. Therefore, people with the PON1 Q/Q genotype would be more susceptible to lung cancer than those with the R/R or Q/R genotypes of the PON1 gene.

여성들의 수유양상 및 수유방식의 선택에 영향 주는 요인들 (Infant Feeding Practices and the Factors that Influence feeding Practices among Women in Seoul and the Chungbuk Area)

  • 김기남;현태선;강남미
    • 대한지역사회영양학회지
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    • 제8권3호
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    • pp.288-301
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    • 2003
  • In order to obtain baseline data for the development of an educational program on breastfeeding, a survey was carried out to investigate infant feeding practices, the characteristics the subjects have in common, and the factors that influence the feeding methods among women in Seoul and the Chungbuk area. Subjects included 671 lactating mothers who visited public health centers or pediatric clinics between December 1999 and February 2000, and were interviewed using a questionnaire. The results were as follows : With respect to feeding methods, the incidence of breastfeeding, formula feeding, mixed feeding and formula feeding switched from breastfeeding was 20.6%, 29.8%, 11.6%, and 38.0%, respectively. With respect to the characteristics the subjects had in common, the incidence of women who planned their infants' feeding methods before pregnancy, during pregancy, and after delivery was 48.7%, 31.0%, and 20.3%, respectively. The incidence of women who started breastfeeding in the hospital after delivery was 38.8%. About seventy seven percet of the subjects had not previously attended an educational program on breastfeeding, and most of these wanted to participate in the future in an educational program to learn about breastfeeding. Some of the topics they were interested in were“Nutritional Management for Sufficient Breast Milk”(60.3%),“Breast Care”(25.0%), and“Correct Nursing Positions”(9.8%). Most (88.2%) of the women who breastfeed suffered from physical discomforts including discomfort of the waist, and legs and discomfort due to cracked or sore nipples. “Insufficient breast milk”was the main reason for breastfeeding cessation or for switching to formula feeding. With respect to formula feeding practices, the main reasons for selecting a specific brand of formula were“the same brand the hospital used after delivery”(34.3%) and“an advertised brand”(23.3%). The strongest factor for promoting breastfeeding was“the support of husband or parents”, next were “breastfeeding in the hospital after delivery”and“planning to breastfeed before pregnancy”in that order. The characteristics the subjects had in common relating to formula feeding were“mother's job”,“high economic level”,“Caesarian section”and “planning to breastfeed after delivery”. In conclusion, it is recommended that breastfeeding be pro-moted, and educational programs be developed and offered as soon as possible to each group which had unfavorable attitudes toward breastfeeding. In addition, the monitoring and supervision of formula advertisements is required to protect consumers from the adverse effects of exaggerated advertising.

치과환자 및 보호자가 인지한 치과위생사 이미지 (A Study on the Image of Dental Hygienists in Dental Patients and Caregivers)

  • 강부월
    • 한국치위생학회지
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    • 제7권2호
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    • pp.197-211
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    • 2007
  • The purpose of this study was to examine the image of dental hygienists. The subjects in the study were 396 patients and their caregivers who visited 14 dental hospitals and dentists' offices in and around Seoul. After a survey was conducted, the following findings were given: 1. The people investigated gave a mean of 4.0 to the image of dental hygienists. Dental hygienists rated highest in terms of looking neat and tidy(4.33), and were given the lowest marks in arbitrary job performance(3.46). 2. There appeared four different types of dental hygienist images, which made a 59.824 prediction of the image of dental hygienists in general. A typical image(4.11) was most dominant, followed by professional one(4.07), personal one(4.01) and social one(3.73). 3. The relations between the general characteristics of the respondents and their image of dental hygienists could be described as below: 1) By age, those who were in their 60s(4.12) had the best image of dental hygienists, and the teenagers(3.90) had the worst image of them. 2) By gender, the men(4.05) looked at dental hygienists more positively than the women(3.96). They had a significantly different opinion on the social image of dental hygienists according to gender(pE0.05). 3) By marital status, the married people(4.00) had a better image of dental hygienists than the unmarried ones(3.95). 4) As for the influence of the type of dental institutions, they had a more favorable image of dental hygienists in dentists' offices(4.13) than in dental hospitals(3.88). There was a broad significant difference in the way they looked at the professional and personal images of dental hygienists according to the type of dental institutions(pE0.001). 5) As to the impact of educational level, those who received community-college or higher education(4.01) had the best image of dental hygienists, and those who received middle-school or lower education(3.91) had the worst image of them. 6) By occupation, the government workers and students(4.07) had the best image of dental hygienists, and the company employees(3.90) had the worst image of them. They took a significantly different view of the social image of dental hygienists according to occupation(pE0.05). 7) Concerning the impact of the frequency of receiving dental treatment, the respondents who had received it seven times or more(4.16) had the best image of dental hygienists, and those who hadn't(3.79) the worst image of them. There was a wide significant gap according to that frequency. The way they looked at the typical, social and professional images of dental hygienists was quite different significantly according to that frequency as well(pE0.001). 8) As for the influence of whether they were accompanied by caregivers or not, the people who weren't accompanied by caregivers(3.99) had a better image of dental hygienists than those who were(3.97).

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신규간호사와 경력간호사의 극복력 비교 (Comparison of Resilience between Novice and Experienced Nurses)

  • 황은희
    • 한국산학기술학회논문지
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    • 제19권10호
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    • pp.530-539
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    • 2018
  • 본 연구의 목적은 병원에서 근무하고 있는 신규간호사와 경력간호사의 극복력, 사회적지지, 사회심리적 스트레스, 소진 정도를 확인하여 비교하는 것이다. 자료수집은 종합병원에 근무하는 임상경력 1년 미만의 신규간호사 65명과 임상경력 7년 이상의 경력간호사 70명을 대상으로 구조화된 설문지를 이용하여 이루어졌다. 수집된 자료는 IBM SPSS 23.0 프로그램을 이용하여 분석하였다. 연구 결과, 신규간호사의 극복력은 경력간호사보다 낮았으며, 교육정도와 직무만족도, 주관적 건강상태에 따라 차이가 있었다. 반면 경력간호사의 극복력은 직위에 따라서 유의한 차이가 있었다. 또한 신규간호사와 경력간호사의 극복력은 사회심리적 스트레스와의 상관성이 가장 높았으며(r=-0.633, p<.001; r=-0.586, p<.001), 신규간호사는 사회적 지지(r=0.560, p<.001), 경력간호사는 소진이(r=-0.404, p=.001) 그 다음 상관성이 높은 변수인 것으로 나타났다. 이러한 결과를 통해 신규간호사와 경력간호사의 극복력의 정도와 관련 요인이 다르다는 것을 알 수 있다. 따라서 신규간호사와 경력간호사의 극복력을 증진하기 위해 각 대상자의 극복력 특성에 따른 차별화된 프로그램의 개발이 필요하다.

대홍의 식품학적 성분 분석 (Food Nutritional Composition of Prunus mume Siebold et Zucc: Dae Hong)

  • 김일출;김정현;이윤원;김영;허상선
    • 한국응용과학기술학회지
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    • 제37권2호
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    • pp.374-384
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    • 2020
  • 본 연구는 매화나무의 새로운 품종인 대홍의 식품학적 가치평가를 분석하기 위해 일반성분, 유리당, 유기산, 아미노산, 무기질 및 비타민 함량 등을 분석하였다. 대홍의 탄수화물은 46.8±0.92%로 가장 높은 함량을 보였고, 조단백질(18.9±0.01%), 수분함량(11.8±0.13%), 조섬유·조지방·회분(5.7±0.94~6.7±0.52%)순으로 검출되었다. 유리당은 5종 검출되었고 mannitol과 fructose가 대부분을 차지하였고, 무기질은 6종이 검출되었으며, K와 P의 함량이 가장 높게 나타났다. 총 페놀함량은 615.99±0.52 mg/100g 이었고 7가지 유형의 필수 아미노산을 포함하여 대홍의 총 아미노산 함량은 121.42 mg/g이었다. 이러한 결과는 대홍이 건강을 위한 혁신적인 식품으로서 혹은 천연식품 방부와 대체재로서 새로운 제품에 포함될 수 있는 가능성을 보여준다.

걷기유형에 따른 심박수 및 에너지소비량 변화에 관한 연구 (The Study of HR and Energy Expenditure Change according to Walking Types)

  • 이형국
    • 한국콘텐츠학회:학술대회논문집
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    • 한국콘텐츠학회 2009년도 춘계 종합학술대회 논문집
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    • pp.405-409
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    • 2009
  • There are many types of walking exercise. We have choice the way according to the walking exercise purpose. Nordic walking(NW) is one of walking types with nordic poles. Also, power walking(PW) has motion of large swing the arm in walking, and dumbbell walking(DW) way is walking with 3-pound dumbbell. This study compared the physiological response(heart rate, energy expenditure) of general walking(GW) to another types(nordic, power, and 3-pound hand weights walking way). Seven apparently male health volunteers between the ages 19 and 24 years participated. Each complete a treadmill test. The tests were assigned randomly, as submaximal walking trials on separate days. Each walking trial was conducted on a level treadmill, for 40 minutes(3-5mile/hour 5min warm-up, 6mile/hour speed for 15min walking and 7mile/hour speed for 15min Jogging exercise, and 5-3mile/hour cool down 5min), at an same pace. Heart rate in beats per minute(bpm), and energy expenditure in kcal per minute(kcal/min) were recorded each minute. Results between trials were compared using repeated measures analysis of variance and Tukey's post hoc tests. In slow walking, it was found that walking with 3-pound hand weight way resulted in and average of ($127.8{\pm}8.27bpm$) the highest score HR, Caloric expenditure($85.4{\pm}14.51kcal/min$), responses compared to regular walking way($117.4{\pm}7.27bpm$ and $70.4{\pm}10.99kcal/min$). Nordic walking way($121.4{\pm}11.74bpm$, and $77.0{\pm}16.83kcal/min$) is second, power walking way($118.5{\pm}9.98bpm$, and $68.7{\pm}20.62kcal/min$) is next. In fast walking, it was found that walking way with 3-pound hand weight resulted in and average of ($160.1{\pm}8.72bpm$) the highest score HR, caloric expenditure($126.1{\pm}13.86kcal/min$), responses compared to regular walking way($148.4{\pm}11.94bpm$, and $109.0{\pm}4.70kcal/min$). Nordic walking way($156.7{\pm}10.82bpm$, and $113.5{\pm}14.51kcal/min$) is second, power walking way($149.7{\pm}12.56bpm$, and $109.2{\pm}17.64kcal/min$) is next. Thus, it is the unavoidable conclusion that, comparing with general walking, 3-pound hand weight walking, nordic walking, and power walking methods have the advantage of high exercise intensity and energy expenditure to meet the purpose of performers without the problem. Furthermore, 3-pound hand weight walking ways were proved to be a useful aerobic exercise method as whole body that achieves high-energy efficiency. To this extent, 3-pound hand weight walking ways can be recommended as a continuous and regulative aerobic exercise for some people.

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산부의 간호요구와 간호원의 간호활동과의 비교 연구 (A Comparative Study of Reported Nursing Needs and Nursing Care During Labor and Delivery)

  • 안혜숙
    • 대한간호학회지
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    • 제6권1호
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    • pp.51-59
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    • 1976
  • Contemporary nursing is concerned with meeting patients physical psychological and secio-economical needs and with helping persons to sore their own problems. At the time of confinement and delivery, women often have physical and psychological disco- mort related to fear, tension or anxiety. Pain related to these causes varies with the individual woman. Effective nursing care to meet individual needs during labor and delivery is important if nurses are to understand and relieve woman's physical and psychological pain. A questionnaire prepared for the purpose by the investigator was administered to 162 women in two general hospitals, one in Seoul and one in TaeGu, during August 1 and September 20, 1975 and to the 13 delivery-room nurses who cared for them. It was hoped that the study would contribute to comprehensive nursing care during labor and delivery and to improve maternal and child health. 1. The sample of mothers ranged in age from 18 to 39; the majority were from 25 to 29 years old (54.3%). Most of them were housewives (87.6%). Sixty-three percent had high school or higher education. They had a range of one to seven deliveries. Sixty-one percent were primiparas Most had some prenatal care (87.6%). 2. The age of the group of nurses ranged from 22 to 39. Ten were 22 or 23. Five of the 13 had from six to ten months experience in the de]ivory room. Twelve were single and ten had a religious affiliation. 3. Both primiparas and multiparas thought equally that physical and psychological care, nursing skills and attitudes were important during labor and delivery, but did not relate basic nursing care directly to normal delivery. Need for nursing care was rated more highly by primiparas (2.83-3.48) than by multiparas (2.51-3.17) (p〈0.05). 4. There was no difference in need for nursing care according to the educational level of the women nor according to whether they had a religious affiliation or not (p〉0.05). 5. There was no difference in the reported nursing care given regarding of the educational preparation of the nurses (p〉 0.05). 6. There the reported nursing needs of the women and the reported nursing care given were compared, physical and psychological nursing care directed toward protecting the mother and fetus and a safe do]ivory were considered important by both groups. Neither group related simple nursing care directly to protection of the mother and fetus or to a safe delivery. The women rated highly their needs for nourishment (3.05) and having a relative with them (2.90) for emotional support but there was little evidence (2.39) that the nurses provided care to meet these needs (p〈0.05). In conclusion, the nursing needs of the women during the three stages of labor and the nursing care given were generally similar. The women had more psychological needs than physical needs but in comparison, nurses gave a little more physical than psychological care. The results point up the need to make adjustments in labor and delivery room nursing care the nurse should Prepared to pay more attention and bigger consideration in psychological comfort care than physical care.

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임상실습에서 학생들이 경험하는 간호과정 적용문제 (The Problems for Application of Nursing Process in Clinical Experience of Nursing Students)

  • 양영희
    • 한국간호교육학회지
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    • 제5권1호
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    • pp.58-71
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    • 1999
  • Nursing process is an essential part for nursing practice. Nursing faculty members must focus on the clinical application for students and try to identify the possible problems that students might face in the fields. The purpose of this study is to examine the actual condition of nursing process education in curricula and to investigate the response of students in clinical experience of nursing process. From 462 students in the 6 associate programs(ADN) and the 6 baccalaureate programs (BSN) data was collected by questionnaire. The results were as followed. 1. Seven programs (58.3%) opened the nursing process in mainly sophomore (BSN) or freshman(ADN). If not opened, the nursing process was taught at the major subjects(espcially fundamental nursing or adult nursing). 2. All Students responded they we supposed to use nursing process in preparing the case report. The majority(94.6%) used NANDA lists for nursing diagnosis and 55.7% of subjects consulted the Korean terms by KNA when translating. The tutors for nursing process in clinical settings were the professor in charge of the subject (68.6) or clinical instructors (48.1%) , assistants(34%). 3. The problems in clinical application that students experienced consisted of 17 items and the mean was 2.27. The biggest problem was 'the lack of the model for RN of applying the nursing process in clinical settings'(2.97). Next the big problem was 'the lack of the competency for implementing the established nursing plans'(2.69). All items were significantly different according to the level of educational programs(ADN or BSN). ADN students had more problems in applying the each step of nursing process and BSN students perceived the NANDA as a guidance of nursing diagnosis and the inconsistency of advices from several instructors or practicum to be mere problematic. 4. The mean of merits after application of nursing process was relatively fair (2.82). The best merit was 'they can identify nursing problems more exactly'(3.07). The second high merit was 'they can study the rational of nursing action' (3.03). BSN than ADN and the subjects of second year than of one year in clinical experience perceived the use of nursing process to be better. Based on this results we need to enforce the application of nursing diagnosis in the class. The use of sample cases can be the efficient method. Students can identify the possible health problems for patient from the cases in imaginary world and discuss them each other. Also we can use the discussion session after practice every other day or as needed. All this is on the good interaction between tutor and student. We must consider to have enough time for student to seize the essence of the nursing process.

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고강도의 윙게이트 테스트 후 식초섭취에 의한 회복기의 에너지기질 변화 연구 (Studies of the Effect of Vinegar Ingestion after the Strenuous Wingate Test on Energy Substrates during Recovery Periods)

  • 송영주;류승필
    • 생명과학회지
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    • 제20권9호
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    • pp.1345-1352
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    • 2010
  • 본 연구에서는 탈진적인 고강도의 운동 후 현미식초 섭취에 의한 2시간에 걸친 회복기의 에너지기질 변화를 분석하고자 7명의 건강한 대학생을 대상으로 3회의 반복적인 윙게이트 테스트를 통하여 피로를 유발하고 15분이 경과되었을 때 현미식초(brown-rice vinegar, BRV) 또는 물(control, CON)을 섭취시켰다. 채혈은 테스트 전, 후, 회복기 30분, 60분, 그리고 120분에 각각 채혈하였으며, 혈중 글루코스, 젖산, 유리지방산, 암모니아, 그리고 코티졸을 분석하였다. 회복 120분이 경과되었을 때, 4회째의 윙게이트 테스트를 실시하여 3회째에 대한 회복율을 계산하였다. 호흡수, 산소포화도, 그리고 심박수는 유의한 변화는 나타나지 않았다. 혈중 글루코스는 회복 120분에 CON이 BRV에 비하여 유의하게 낮았으며, 혈중 젖산과 암모니아 농도는 회복 60분과 120분에 BRV가 유의하게 낮았고, BRV에서 회복 60분과 120분에 유리지방산 농도가 유의하게 높았다. 윙게이트 테스트의 최대파워 회복율과 체중당 최대파워의 회복 율은 BRV에서 유의한 증가가 나타났다. 이러한 결과는 탈진적인 고강도의 운동 후 현미식초의 섭취에 의해 피로의 회복이 촉진되며, 하루에 두 번 혹은 그 이상 개최되는 경기에 있어서도 효과적인 영양보조물로 사용될 수 있다는 점을 시사한다.