• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.24 no.2
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• pp.153-158
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• 2006

A new High Resolution Geometry or HRG imaging instrument is developed by CNES to be carried on-board SPOT 5. The HRG instrument offers a higher ground resolution than that of the HRV/HRVIR on SPOT 1 - 4 satellites. The field width of HRG is 60 km, same as SPOT constellation. With two HRG instruments, a maximum swath of 120 km at 5 m resolution can be achieved. The generation of Digital Elevation Models (DEMs) from satellite stereo images scores over conventional methods of DEM generation using topographic maps and aerial photographs. This global availability of satellite images allows for quicker data processing for an equivalent area. In this study, a HRG stereo images of SPOT 5 over JECHEON has been used with Leica Photogrammetry Suite OrthoBASE Pro tool for the creation of a digital elevation model (DEM). The extracted DEM was compared to the reference DEM obtained from the contours of digital topographic map.

• Korean Journal of Exercise Nutrition
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• v.14 no.2
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• pp.63-68
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• 2010

This study evaluated the effects of high pressured red ginseng(HRG) and ginseng berry(GB) supplementation on lipid profiles and run to exercise time in SD rats. Five weeks-old male rats were randomly assigned into six groups, ie. control group(AC: n = 8), exercise group(AE: n = 7), general extracted red ginseng group(C: n = 8), HRG group(high density D: n = 8, low density E: n = 7), and HRG + GB group(F: n = 7). The AC and AE groups had a supplementation of AIN-93G, and AE group performed 40 min treadmill exercise five times per week for five weeks. E, C, D, and F groups had a supplementation composed of general extracted red ginseng(GRG), HRG(250 mpk and 500 mpk), and HRG(250 mpk) + GB(167 mpk) in the AIN-93G. Main results of the study were as follow 1) the duration of running time to exhaustion was higher in exercise group compared to other groups. HRG had no effect on run to exhaustion time, but, GRG and HRG + GB showed longer run time than control groups. 2) Blood TC, TG, HDL-C and liver TG showed no difference between groups, but, liver TC showed lower level in the HRG groups than other groups. It was concluded that the 5 weeks of supplementation of HRG extract would have positive effects on liver cholesterol, and GRG and HRG + GB have a positive effect on exercise performance tested run to exhaustion time, but, we can not find a positive effect of supplementation of HRG on exercise performance.

• Journal of Korean Society for Geospatial Information Science
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• v.14 no.4 s.38
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• pp.61-70
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• 2006

This paper presents photogrammetric processing to generate digital elevation models using SPOT-5 HRG stereo images and deals with the accuracy potential of HRG (High Resolution Geometry) supermode imagery for DEM generation. After bundle adjustment was preformed for sensor modelling, digital surface models were generated through the procedures of Epipolar image resampling and image matching. The DEM extracted from HRG imagery was compared along several test sections with the the refernce DEM which was obtained from the digital topographic maps of a scale of 1 to 5000. The ratio of the zone with DEM errors less than 5m to the whole zone was 53.8%, and about 2.5m RMSE was showed when assuming that the zones larger than 5m were affected by clouds, water bodies and buildings and excluding those zones from accuracy evaluation. In addition, the three-dimensional bird's eye view model and 3D building model were producted based on the DSM which was extracted from SPOT-5 HRG data.

• ALGAE
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• v.36 no.3
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• pp.207-217
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• 2021

An increase in seawater temperature owing to global warming is expected to substantially limit the growth of marine algae, including Pyropia yezoensis, a commercially valuable red alga. To improve our knowledge of the genes involved in the acquisition of heat tolerance in P. yezoensis, transcriptomes sequences were obtained from both the wild-type SG104 P. yezoensis and heat-tolerant mutant Gy500. We selected 1,251 differentially expressed genes that were up- or downregulated in response to the heat stress condition and in the heat-tolerant mutant Gy500, based on fragment per million reads expression values. Among them, PyHRG1 was downregulated under heat stress in SG104 and expressed at a low level in Gy500. PyHRG1 encodes a secretory protein of 26.5 kDa. PyHRG1 shows no significant sequence homology with any known genes deposited in public databases to date. However, PyHRG1 homologs were found in other red algae, including other Pyropia species. When PyHRG1 was introduced into the single-cell green alga Chlamydomonas reinhardtii, transformed cells overexpressing PyHRG1 showed severely retarded growth. These results demonstrate that PyHRG1 encodes a novel red algae-specific protein and plays a role in heat tolerance in algae. The transcriptome sequences obtained in this study, which include PyHRG1, will facilitate future studies to understand the molecular mechanisms involved in heat tolerance in red algae.

• CELLMED
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• v.2 no.3
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• pp.27.1-27.6
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• 2012

Red ginseng, which has a variety of biological and pharmacological activities including antioxidant, anti-inflammatory, antimutagenic and anticarcinogenic effects, has been used for thousands of years as a general tonic in traditional oriental medicine. Here, we tested the immune regulatory activities of hydrolyzed red ginseng by malted barley (HRG) on the expressions of receptor interacting proteins (Rip) 2 and $I{\kappa}B$ kinase-beta (IKK-${\beta}$) in mouse peritoneal macrophages. We show that HRG increased the activations of Rip 2 and IKK-${\beta}$ for the first time. When HRG was used in combination with recombinant interferon-${\gamma}$ (rIFN-${\gamma}$), there was a marked cooperative induction of nitric oxide (NO) production. The increased expression of inducible NO synthase from rIFN-${\gamma}$ plus HRG-stimulated cells was almost completely inhibited by pre-treatment with pyrrolidine dithiocarbamate (PDTC), an inhibitor of nuclear factor-${\kappa}B$ (NF-${\kappa}B$). In addition, the treatment of peritoneal macrophages with rIFN-${\gamma}$ plus HRG caused significant increases in tumor necrosis factor (TNF)-${\alpha}$ mRNA expression and production. Because NO and TNF-${\alpha}$ play an important role in the immune function and host defense, HRG treatment can modulate several aspects of the host defense mechanisms as a result of the stimulations of the inducible nitric oxide synthase and NF-${\kappa}B$. In conclusion, our findings demonstrate that HRG increases the productions of NO and TNF-${\alpha}$ from rIFN-${\gamma}$-primed macrophages and suggest that Rip2/IKK-${\beta}$ plays a critical role in mediating these immune regulatory effects of HRG.

• Proceedings of the Korea Contents Association Conference
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• 2005.11a
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• pp.335-339
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• 2005

Digital elevation models(DEM) were generated from SPOT-5 HRG supermode imagery through photogrammetric processing. The reference DEMs were obtained from digital topographic maps of 1/5000 scaleas for analyzing the accuracy of the generated DEMs. The DEMs extracted from HRG stereo image data were compared with digital topograpic map DEMs on several test sections. And digital surface models(DSM) and 3D building model was produced.

• Journal of Sensor Science and Technology
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• v.21 no.3
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• pp.204-210
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• 2012

In this paper, signal detection and control circuits for hemispherical resonator gyroscope(HRG) are designed, simulated and tested. HRG is one of the coriolis vibratory gyroscope(CVG) which has very stable quartz hemispherical resonator and shows very precise performance. HRG signals are usually modulated at the several kHz of resonant frequency. So the general control scheme cannot be applied directly because general control schemes mainly focused at low frequency range. Using demodulated and modulated PI control scheme with the signal detection which is presented in this paper, performance of manufactured HRG has tested.

• Preventive Nutrition and Food Science
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• v.20 no.4
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• pp.253-259
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• 2015

Chronic low-grade inflammation is associated with obesity. This study investigated effect of high hydrostatic pressure extract of red ginseng (HRG) on inflammation in rats with high-fat (HF) diet induced obesity. Male, Sprague-Dawley rats (80~110 g) were randomly divided into two groups, and fed a 45% HF diet (HF) and a 45% HF diet containing 1.5% HRG (HF+HRG) for 14 weeks. At the end of the experiment, the serum leptin level was reduced by the HRG supplementation. The mRNA expression of genes related to adipogenesis including peroxisome proliferator-activated receptor-gamma and adipocyte protein 2 was down-regulated in the white adipose tissue (WAT). The mRNA levels of major inflammatory cytokines such as tumor necrosis factor-${\alpha}$, monocyte chemoattractant protein 1, and interleukin-6 were remarkably down-regulated by the HRG in WAT. These results suggest that HRG might be beneficial in ameliorating the inflammation-associated health complications by suppressing adipogenic and pro-inflammatory gene expression.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.21 no.3
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• pp.255-260
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• 2003

In this paper, we generate the 3D geometric sensor model of SPOT-5 HRG stereo images which are processed in Supermode and have 2.5m ground spatial resolution, and calculate the RPC(Rational Polynomial Coefficients) for acquisition of topographic information using the exterior orientation parameters which are determined in the 3D geometric sensor modelling process. It is shown that SPOT-5 images can be modelled with me 3.3m accuracy by the bundle adjustment method used to model the existing SPOT series. Considering the accuracy of RPC's results with rmse 0.03m accuracy, the RPC model can replace the sensor model, if we emphasize the simplification and the cost.

• Journal of Applied Biological Chemistry
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• v.54 no.1
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• pp.15-20
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• 2011

Red ginseng is one of the most popular traditional medicines in Korea. In this study, we developed a new technique in which ethanol extract of $\underline{r}$ed $\underline{g}$inseng (HRG) was exposed to the $Co^{60}$ gamma radiation ranging from 1~5 kGy. The irradiated HRG (IHRG) were analyzed by high performance liquid chromatography (HPLC) to determine any compositional changes of ginsenosides due to irradiation. No appreciable difference was observed in the HPLC pattern of ginsenosides of HRG. Using MTT assay, the cytotoxicity effect was significantly increased by IHRG compared to HRG. The $LD_{50}$ concentration was $30{\mu}g/mL$ for IHRG-1 (1 kGy), and $15{\mu}g/mL$ for IHRG-5 (5 kGy). The evidences of apoptosis, such as nuclei cleavage and Annexin V staining, were observed in the human prostate cancer PC-3 cells treated with the IHRG. Additionally, the level of reactive oxygen species (ROS) was apparently elevated by IHRG. We also studied the inhibitory effect of IHRG on the growth rate of tumor xenografts in BALB/c male mice. The tumor growth rates were inhibited by 56.9 and 76.1% in mice treated with 10 mg/kg of IHRG-1 and IHRG-5, respectively, compared with control group (21.1%). These results suggest that some biologically active and soluble components in HRG can be more effectively enhancement of anti-tumor effects using irradiation.