• Title/Summary/Keyword: HP1

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Relationship between Helicobacter pylori infection and iron-deficiency anemia in infants and children (영유아에서 Helicobacter pylori 감염과 철결핍성 빈혈과의 관계 연구)

  • Son, Meong Hi;Yeom, Jung Suk;Park, Ji Suk;Park, Eun Sil;Seo, Ji Hyun;Lim, Jae Young;Park, Chan Hoo;Woo, Hyang Ok;Youn, Hee Shang
    • Clinical and Experimental Pediatrics
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    • v.52 no.5
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    • pp.544-548
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    • 2009
  • Purpose : To elucidate a potential association between Helicobacter pylori (HP) infection and iron-deficiency anemia (IDA) in infants and children in terms of the other factors related to iron utilization and storage although the association of ferritin was previously studied. Methods : We evaluated 135 infants (aged 6-24 months) admitted at Gyeongsang National University Hospital from 2000 to 2006. Western blot assays using the HP CagA antigen (120 kD) were conducted to identify infections. The concentrations of six parameters were measured: hemoglobin (Hb), serum ferritin, soluble serum transferrin receptors, interleukin-6, prohepcidin, and C-reactive protein. In addition, the infants were classified into IDA, anemia from inflammation (AI), unclassified anemia (UCA), and normal groups on the basis of Hb and ferritin concentrations. Results : In the IDA group (n=20), seven infants were infected with HP, with the other infants showing no evidence of infection. The mean Hb levels in the IDA group were significantly lower in HP-infected infants than those uninfected (7.1 vs. 8.2 g/dL, respectively); the mean ferritin levels were also significantly lower in the infected infants (3.2 vs. $6.8{\mu}g/L$). The other four parameters did not differ significantly among the IDA infants. No correlations were found between the six parameters and HP infection status in the other groups. Conclusion : There were no significant differences in the HP infection rates among the study groups. However, in the IDA group, the HP-infected infants had significantly lower serum ferritin and Hb levels than the HP-negative infants (P<0.05).

Inactivation Efficiency of Escherichia coli and Listeria monocytogenes in Ground Pork by Combination of Natural Food Ingredients and High Pressure Processing

  • Jung, Samooel;Yun, Hye-Jeong;Kim, Hyun-Joo;Ham, Jun-Sang;Kim, Il-Suk;Lee, Moo-Ha;Jo, Cheorun
    • Food Science of Animal Resources
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    • v.32 no.1
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    • pp.1-5
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    • 2012
  • The objective of this study was to examine the effects of a combined treatment regarding antimicrobial food ingredients and high pressure processing (HP) on the inactivation efficiency of Escherichia coli and Listeria monocytogenes inoculated into ground pork. Ethanol extracted from garlic, leeks, onions, and ginger powder was prepared. Half of the prepared powder was irradiated at 5 kGy to see the effect of pasteurization before addition. The prepared food ingredients were added into radiation-sterilized ground pork (1%, w/w), and inoculated with E. coli and L. monocytogenes. The samples were vacuum-packed and applied with HP at 0.1 (control), 300, 450, and 600 MPa. Microbial log reduction increased with the increase of pressure up to 600 MPa. With minor exceptions, overall efficiency of HP treatment with regards to inactivation of pathogens increased. Inoculated microorganisms showed approximately 7-8 Log reductions by 600 MPa, except for L. monocytogenes treated with garlic (5.7 Log reductions). The E. coli reduction in ground pork mixed with ethanol extracted garlic showed the highest efficiency (1.86) compared to leeks (1.25-1.31), onions (1.17-1.44), and ginger (1.50-1.82) when treated at an HP of 450 MPa. There was no evidence for the advantage of pasteurization concerning the food ingredients before addition of antimicrobial food ingredients and HP. Results demonstrate that the combination of antimicrobial food ingredients and HP treatment may help improve the efficiency of sterilization in meat systems.

Effects of the plane of nutrition for grower pigs on their grow-finish performance and meat quality in winter

  • Yang, Bo-Seok;Kim, Myeong Hyeon;Choi, Jung-Seok;Jin, Sang Keun;Park, Man-Jong;Song, Young-Min;Lee, Chul Young
    • Journal of Animal Science and Technology
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    • v.61 no.1
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    • pp.1-9
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    • 2019
  • Little is known about the effects of the plane of nutrition on growth performance and meat quality of grow-finish pigs under commercial production conditions. The present study was thus addressed to this virtually unanswered question. One hundred and two barrows and 102 gilts weighing approximately 24 kg were fed phase I and II grower diets with a high, medium, or low plane of nutrition (HP, MP, or LP) to approximately 43 and 70 kg, respectively, in 6 replicates (pens). Subsequently, the HP and MP groups were fed the HP and MP1 finisher diets, respectively, the LP group being fed a second MP (MP2) finisher diet (LP1 group). Moreover, 68 LP-grower-fed barrows and gilts were added to the feeding trial and fed the MP1 and LP finisher diets to approximately 95 kg and thereafter, respectively (LP2 group). All MP diets had the lysine:calorie ratios comparable to the RNC recommendations, with < 18% differences between those of the HP and LP diets. The finisher pigs were reared in 16 pens and slaughtered at approximately 115 kg. The gain:feed ratio, but not average daily gain (ADG), was greater for the HP group than for the MP and LP during the grower phase I whereas during the grower phase II, ADG was greater (p < 0.05) for the HP and LP groups vs. MP. During the finisher phase I, ADG was less for the LP (LP1 + LP2) group vs. HP and MP, with no difference between the HP and MP groups; the gain:feed ratio was less for the LP vs. MP group. Backfat thickness was greater for the LP vs. HP group. The water holding capacity of fresh longissimus dorsi muscle (LM) and the sensory juiciness score for cooked LM were greatest for the LP group, the sensory flavor and tenderness scores being greater for the LP group vs. MP. In conclusion, results suggest that compensatory growth occurred for the LP and MP groups during the grower phase II and finisher phase I, respectively, with fat deposition increased for the LP group and that meat quality could be improved by the use of LP.

THE HP-VERSION OF THE FINITE ELEMENT METHOD UNDER NUMERICAL QUADRATURE RULES

  • Kim, Ik-Sung
    • East Asian mathematical journal
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    • v.14 no.1
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    • pp.63-76
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    • 1998
  • we consider the hp-version to solve non-constant coefficients elliptic equations $-div(a{\nabla}u)=f$ with Dirichlet boundary conditions on a bounded polygonal domain $\Omega$ in $R^2$. In [6], M. Suri obtained an optimal error-estimate for the hp-version: ${\parallel}u-u^h_p{\parallel}_{1,\Omega}{\leq}Cp^{(\sigma-1)}h^{min(p,\sigma-1)}{\parallel}u{\parallel}_{\sigma,\Omega}$. This optimal result follows under the assumption that all integrations are performed exactly. In practice, the integrals are seldom computed exactly. The numerical quadrature rule scheme is needed to compute the integrals in the variational formulation of the discrete problem. In this paper we consider a family $G_p=\{I_m\}$ of numerical quadrature rules satisfying certain properties, which can be used for calculating the integrals. Under the numerical quadrature rules we will give the variational form of our non-constant coefficients elliptic problem and derive an error estimate of ${\parallel}u-\tilde{u}^h_p{\parallel}_{1,\Omega}$.

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Comparison of the non-invasive diagnostic methods, stool antigen test and PCR assay, for Helicobacter felis detection in dogs

  • Hong, Sunhwa;Lee, Hak-Yong;Kim, Tae-Wan;Kim, Okjin
    • Korean Journal of Veterinary Service
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    • v.38 no.1
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    • pp.37-42
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    • 2015
  • The aim of the present study was to compare the non-invasive methods for the diagnosis of H. felis with HpSA kit-based detection method and H. felis-specific PCR assay with dog's stool samples without sacrifice. Male Beagle dogs (n=6) were infected with H. felis ATCC 49179 ($1.0{\times}10^9CFU/dog$) by intra-gastric inoculation two times at 3-day intervals, and the stool specimens of dogs were collected 1, 3, 5, 7, 14, 21 days after infection to submit to HpSA test and H. felis-specific PCR. As the results, the sensitivity of the HpSA and the PCR analysis was 50.0%, 83.3% respectively. Although HpSA test is less sensitive, it could be used for rapid, cheap and easy screening assay for H. felis infection in dog and cats. We suggest that the H. pylori stool antigen kit, HpSA, is useful and effective for monitoring H. felis infection. If HpSA test would be made with H. felis antibodies in the future, its sensitivity could be increased. Also, PCR assay could be successfully used to detect the H. felis in stools. Applying the H. pylori stool antigen kit and PCR assay may be the recommended non-invasive strategy to identify H. felis in dog and cats.

A Study on the Collision Nozzle for Generating Microbubble by Self-Suction Method (자흡방식에 의해 마이크로버블을 발생시키는 충돌 노즐에 대한 연구)

  • Woo-Jin Kang;Sang-Hee Park;Seong-Hun Yu
    • Journal of the Korean Society of Industry Convergence
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    • v.26 no.6_2
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    • pp.1047-1053
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    • 2023
  • An experimental study was performed on the collision nozzle system that generates microbubble by air self-suction using a venturi nozzle. This study experimentally investigates the pressure of a pump and a dissolution tank, water flow rate, air self-suction amount and microbubble generation amount. The experimental conditions were varied by changing the diameter of the collision nozzle (de=4,5,6,7,8mm), the pumping power(0.5hp, 1.0hp) and the capacity of the dissolution tank(4.4L, 8/8L). The pressure change of the pump according to the outlet diameter of the collision nozzle showed that the 1.0hp pump power operated more stably than the 0.5hp pump. The pressure change in the dissolution tank was shown to decrease rapidly as the outlet diameter of the nozzle increased. The flow rate of recirculating water was shown to increase as the nozzle diameter increased. Additionally, it was shown that the pump capacity of 1.0hp increased the flow rate more than that of 0.5hp. The self-suction air flow rate was shown to occur above de=6mm, and the air flow rate increased as the nozzle diameter increased. Also, as the pump capacity increased, the self-suction amount of air increased. It was shown that the amount of microbubble less than 50mm generated was maximum when the nozzle diameter was 6mm, the pump power was 1.0hp, and the dissolution tank capacity was 8.8L.

Electrical Properties and Fabrication of Ultra-thin Films using p-HP Polymer (p-HP 고분자 LB초박막의 제작과 전기적 특성)

  • Yu, Seung-Yeop;Jeong, Sang-Beom;Park, Jae-Cheol;Gwon, Yeong-Su
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.51 no.7
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    • pp.287-291
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    • 2002
  • We fabricated the crosslinked films using p-hexadecoxyphenol (p-HP), which is amphiphilic and can form polyion complexes with formaldehyde at the air-water interface. The behavior of polyion complexation at the air-water interface and the surface structure of LB films was investigated by Brewster angle microscope(BAM) and scanning Maxwell-stress microscope (SMM), respectively. Also, the electrical properties for crosslinking in phenol-formaldehyde LB films were investigated by measuring conductivity and dielectric constant. The conductivities of p-HP LB films are as follows: heat-treatment of 1% formaldehyde subphase(3.76$\times$10$^{-15}$ ~4.76$\times$10$^{-1}$5[S/cm])$\times$10$^{-14}$ ~1.74$\times$10$^{-14}$ [S/cm]). Also, relative dielectric constants of p-HP LB films were reduced from 6.76~7.84 (pure water) to 2.97~3.25 (heat-treatment of 1% formaldehyde subphase))

Spectroscopic Studies on Interaction of Protoberberines with the Deoxyoligonucleotide d(GCCGTCGTTTTACA)2

  • Park, Hye-Seo;Kim, Eun-Hee;Kang, Mi-Ran;Chung, In-Kwon;Cheong, Chae-Joon;Lee, Weon-Tae
    • Bulletin of the Korean Chemical Society
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    • v.25 no.10
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    • pp.1559-1563
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    • 2004
  • The topoisomerase II poisoning effect of certain protoberberine alkaloids is associated with anti-cancer activity. Structure-activity relationships of protoberberine analogues substituted on the ring protons reveal that substitution at the C19 position is an important determinant of biological activity. In this study, the effects of substituent modification at the C19 position on the interaction of protoberberines with DNA are determined using UV and NMR spectroscopy. The line broadening effect on aliphatic resonances, chemical shift changes of the imino protons of HP14 upon berberine and berberrubine binding to HP14, and the rate of the exchange process between protoberberine analogs bound indicate that berberrubine binds HP14 more specifically than berberine. In addition, the free HP14 is altered by the substituent at the 19-position. UV spectra of berberrubine have shown a hypochromic effect together with a slight red shift, which are usually regarded as characteristics of DNA intercalation. These results are consistent with our previous report that the berberrubine is partially intercalated with HP14 with molar ratio 1 : 1, whereas a non-specific interaction is predominant between the berberine and HP14.

Effects of Sweet Persimmon Powder Type on Quality Properties of Low Salted Pork Patties during Cold Storage (단감분말 첨가 유형에 따른 저염 미트패티제품의 저온저장 중 품질특성)

  • Kim, I.S.;Jin, S.K.;Ha, C.J.
    • Journal of Animal Science and Technology
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    • v.50 no.1
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    • pp.133-144
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    • 2008
  • Four different pork patties were made with two levels, HP/FP-3% and HP/FP-6%, containing 3.0 and 6.0% HP(hot air dried sweet persimmon powder)/FP(freeze-dried sweet persimmon powder), respectively. After manufacture, the meat patties were packaged with  polyvinyl wrap and stored at 4℃ for 8 days. CTL(control) and HP-3% meat patties were significantly(p<0.05) higher in moisture content than the other samples. FP-6% was found higher in protein content than the other treatments. FP-3% had a higher fat content than other meat patty samples. However, ash contents were not found significantly(p>0.05) different among the meat patty samples. The value of pH, L* and a* values were decreased as the cold storage time increased in all treatments(p<0.05). WHC(water holding capacity) of CTL and HP-6% and cooking loss of HP-3% were significantly(p<0.05) decreased with increased storage period. The diameter and thickness of all meat patties decreased with increasing the storage period. VBN(volatile basic nitrogen) values of all meat patties were increased(p<0.05) with increased storage period. TBARS (thiobarbituric acid reactive substance) of treatments were higher than that of CTL during whole storage time. The number of microorganisms(Total plate counts, Escherichia coli.) were maintained below 4.61 log10 CFU/cm2 during the whole storage period. In sensory evaluation, treatment groups had higher(p<0.05) scores in aroma, flavor, color and overall acceptability.

Effects of 3.5% Hydrogen Peroxide Containing Dicalcium Phosphate Dihydrate on the Tooth Enamel Surface (Dicalcium Phosphate Dihydrate를 함유한 3.5% 과산화수소가 치아표면에 미치는 영향)

  • Shim, Youn-Soo
    • Journal of dental hygiene science
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    • v.12 no.4
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    • pp.320-328
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    • 2012
  • The purpose of this study was to evaluate the tooth whitening and properties of an enamel surface after treatments with tooth bleaching agents that contained dicalcium phosphate dihydrate (DCPD) and hydrogen peroxide (HP). Thirty specimens were obtained from fifteen premolar and were randomly divided into three groups (n=10): 1, 3.5% HP + 0 g DCPD; 2, 3.5% HP + 0.1 g DCPD; 3. 3.5% HP + 1 g DCPD. All groups were bleached 8 hours per day for 14 days. With increasing DCPD concentration, the pH values in the agents increased, making it less acidic. However, there was no statistically significant difference (p>.05). As the concentration of DCPD was increased, the concentration of Ca and P was also increased. In all groups, after the tooth whitening, the tooth color was found to have a value of $L^*$ (p<.05). All groups showed significantly decreased enamel microhardness compared to their baseline (p<.05). The percentage microhardness loss (PML) of the group A1 and A2 were significantly lower than that of group A3. The obvious variation of morphology was observed on enamel surfaces in group A1. Following an analysis of the constituents of enamel surface after bleaching, as DCPD content was increased, the amount of Ca and P was increased. In this study, the experimental results suggest that DCPD/HP agent less demineralization changes such as the erosion morphology and hardness loss without compromising whitening efficiency.