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Impact of maternal crowd on the reproductive performance of an ecto-pupal parasitoid Nesolynx thymus (Hymenoptera: Eulophidae)

  • Siddaiah, Aruna Ambadahalli;Danagoudra, Manjunath
    • International Journal of Industrial Entomology and Biomaterials
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    • v.29 no.1
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    • pp.128-134
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    • 2014
  • Nesolynx thymus Girault (Hymenoptera: Eulophidae) is one among 20 hymenopteran parasitoids reported to attack the uzi fly, Exorista bombycis, which in turn infests the silkworm, Bombyx mori accounting a cocoon yield loss of 10-20%. A host of factors viz., age and size of host, age and size of parasitoid, availability of host, temperature and quality of host are reported to influence the reproductive efficiency of the parasitoids. In the present study an attempt was made to record the influence of foraging parasitoid density on their reproductive performance. Three day-old uzi pupae were offered to varying numbers (1 - 10) of 2 day old Nesolynx thymus adults for parasitization. The progeny production per pupa (84.44 - 132.77) increased significantly with increase in the number of foraging parasitoid adults (1 - 10) however, progeny production per female decreased. The sex ratio (M : F) (1:25.49 - 1:1.53) decreased significantly with increase in foraging parasitoid adults. The morphometric parameters except female abdomen width of first generation parasitoid showed significant negative correlation with number of foraging adults. However, correlation between the parasitoid size in first generation and their reproductive performance was nonsignificant.

HCoV-IMDB: Database for the Analysis of Interactions between HCoV and Host Immune Proteins

  • Kim, Mi-Ran;Lee, Ji-Hae;Son, Hyeon Seok;Kim, Hayeon
    • International journal of advanced smart convergence
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    • v.8 no.1
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    • pp.1-8
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    • 2019
  • Coronaviruses are known respiratory pathogens. In the past, most human coronaviruses were thought to cause mild symptoms such as cold. However recently, as seen in the Severe Acute Respiratory Syndrome (SARS) and the Middle East Respiratory Syndrome (MERS), infectious diseases with severe pulmonary disease and respiratory symptoms are caused by coronaviruses, making research on coronaviruses become important. Considering previous studies, we constructed 'HCoV-IMDB (Human Corona Virus Immune Database)' to systematically provide genetic information on human coronavirus and host immune information, which can be used to analyze the interaction between human coronavirus and host immune proteins. The 'HCoV-IMDB' constructed in the study can be used to search for genetic information on human coronavirus and host immune protein and to download data. A BLAST search specific to the human coronavirus, one of the database functions, can be used to infer genetic information and evolutionary relationship about the query sequence.

Performance Evaluation of HMB-Supported DRAM-Less NVMe SSDs (HMB를 지원하는 DRAM-Less NVMe SSD의 성능 평가)

  • Kim, Kyu Sik;Kim, Tae Seok
    • KIPS Transactions on Computer and Communication Systems
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    • v.8 no.7
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    • pp.159-166
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    • 2019
  • Unlike modern Solid-State Drives with DRAM, DRAM-less SSDs do not have DRAM because they are cheap and consume less power. Obviously, they have performance degradation problem due to lack of DRAM in the controller and this problem can be alleviated by utilizing host memory buffer(HMB) feature of NVMe, which allows SSDs to utilize the DRAM of host. In this paper, we show that commercial DRAM-less SSDs surely exhibit lower I/O performance than other SSDs with DRAM, but they can be improved by utilizing the HMB feature. Through various experiments and analysis, we also show that DRAM-less SSDs mainly exploit the DRAM of host as mapping table cache rather than read cache or write buffer to improve I/O performance.

A study on the outbound traffic controller for prevention of ICMP attacks (ICMP 공격 방지를 위한 outbound traffic controller에 관한 연구)

  • Yoo, Kwon-joeong;Kim, Eun-gi
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2016.10a
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    • pp.759-761
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    • 2016
  • ICMP(Internet Control Message Protocol) supports the processing of error in the communication network based TCP/IP. If a problem is occurred in a data transmission process, router or receiving host sends ICMP message containing the error cause to sending host. However, in this process an attacker sends a fake ICMP message to the host so that the communication between the hosts can be abnormally terminated. In this paper, we performed a study to prevent several attacks related to ICMP. To this, we have designed outbound traffic controller so that attack packet is not transmitted to network in operating system of host.

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Molecular Perspectives of SARS-CoV-2: Pathology, Immune Evasion, and Therapeutic Interventions

  • Shah, Masaud;Woo, Hyun Goo
    • Molecules and Cells
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    • v.44 no.6
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    • pp.408-421
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    • 2021
  • The outbreak of coronavirus disease 2019 (COVID-19) has not only affected human health but also diverted the focus of research and derailed the world economy over the past year. Recently, vaccination against COVID-19 has begun, but further studies on effective therapeutic agents are still needed. The severity of COVID-19 is attributable to several factors such as the dysfunctional host immune response manifested by uncontrolled viral replication, type I interferon suppression, and release of impaired cytokines by the infected resident and recruited cells. Due to the evolving pathophysiology and direct involvement of the host immune system in COVID-19, the use of immune-modulating drugs is still challenging. For the use of immune-modulating drugs in severe COVID-19, it is important to balance the fight between the aggravated immune system and suppression of immune defense against the virus that causes secondary infection. In addition, the interplaying events that occur during virus-host interactions, such as activation of the host immune system, immune evasion mechanism of the virus, and manifestation of different stages of COVID-19, are disjunctive and require thorough streamlining. This review provides an update on the immunotherapeutic interventions implemented to combat COVID-19 along with the understanding of molecular aspects of the immune evasion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which may provide opportunities to develop more effective and promising therapeutics.

Signaling Role of NADPH Oxidases in ROS-Dependent Host Cell Death Induced by Pathogenic Entamoeba histolytica

  • Lee, Young Ah;Sim, Seobo;Kim, Kyeong Ah;Shin, Myeong Heon
    • Parasites, Hosts and Diseases
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    • v.60 no.3
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    • pp.155-161
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    • 2022
  • All living organisms are destined to die. Cells, the core of those living creatures, move toward the irresistible direction of death. The question of how to die is critical and is very interesting. There are various types of death in life, including natural death, accidental death, questionable death, suicide, and homicide. The mechanisms and molecules involved in cell death also differ depending on the type of death. The dysenteric amoeba, E. histolytica, designated by the German zoologist Fritz Schaudinn in 1903, has the meaning of tissue lysis; i.e., tissue destroying, in its name. It was initially thought that the amoebae lyse tissue very quickly leading to cell death called necrosis. However, advances in measuring cell death have allowed us to more clearly investigate the various forms of cell death induced by amoeba. Increasing evidence has shown that E. histolytica can cause host cell death through induction of various intracellular signaling pathways. Understanding of the mechanisms and signaling molecules involved in host cell death induced by amoeba can provide new insights on the tissue pathology and parasitism in human amoebiasis. In this review, we emphasized on the signaling role of NADPH oxidases in reactive oxygen species (ROS)-dependent cell death by pathogenic E. histolytica.

Intestinal organoids as advanced modeling platforms to study the role of host-microbiome interaction in homeostasis and disease

  • Ji-Su Ahn;Min-Jung Kang;Yoojin Seo;Hyung-Sik Kim
    • BMB Reports
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    • v.56 no.1
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    • pp.15-23
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    • 2023
  • After birth, animals are colonized by a diverse community of microorganisms. The digestive tract is known to contain the largest number of microbiome in the body. With emergence of the gut-brain axis, the importance of gut microbiome and its metabolites in host health has been extensively studied in recent years. The establishment of organoid culture systems has contributed to studying intestinal pathophysiology by replacing current limited models. Owing to their architectural and functional complexity similar to a real organ, co-culture of intestinal organoids with gut microbiome can provide mechanistic insights into the detrimental role of pathobiont and the homeostatic function of commensal symbiont. Here organoid-based bacterial co-culture techniques for modeling host-microbe interactions are reviewed. This review also summarizes representative studies that explore impact of enteric microorganisms on intestinal organoids to provide a better understanding of host-microbe interaction in the context of homeostasis and disease.

Virus Test bed using VMware in Preparation for the Mobile IP Generation (Mobile IP 세대를 대비한 VMware 기반의 바이러스 Test bed)

  • Kim, Hong-Il
    • Journal of Korea Society of Industrial Information Systems
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    • v.14 no.1
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    • pp.56-63
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    • 2009
  • Contrast operating system installed on traditional PC, operating system installed to mobile IP host is a status not to be established a definite monopoly system. Accordingly, for the time being, it is expected that operating system operated in mobile IP host will be used various operating systems. Regardless of operating system, this condition is a very vulnerable to modified virus. Because operating system used in an individual host is very diverse, It makes technical development to cure complicated in detection efficiently these virus. In this thesis, By using VMware under the various operating system, I designed and implemented system which is able to test a modified virus. Also I implemented prototype system to operate under the real mobile condition.

Diversity and community structure of ectomycorrhizal mycorrhizal fungi in roots and rhizosphere soil of Abies koreana and Taxus cuspidata in Mt. Halla

  • Ji-Eun Lee;Ahn-Heum Eom
    • Mycobiology
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    • v.50 no.6
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    • pp.448-456
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    • 2022
  • In this study, the roots and rhizosphere soil of Abies koreana and Taxus cuspidata were collected from sites at two different altitudes on Mt. Halla. Ectomycorrhizal fungi (EMF) were identified by Illumina MiSeq sequencing. The proportion of EMF from the roots was 89% in A. koreana and 69% in T. cuspidata. Among EMF in rhizosphere soils, the genus Russula was the most abundant in roots of A. koreana (p < 0.05). The altitude did not affect the biodiversity of EMF communities but influenced fungal community composition. However, the host plants had the most significant effect on EMF communities. The result of the EMF community analysis showed that even if the EMF were isolated from the same altitudes, the EMF communities differed according to the host plant. The community similarity index of EMF in the roots of A. koreana was higher than that of T. cuspidata (p < 0.05). The results show that both altitude and host plants influenced the structure of EMF communities. Conifers inhabiting harsh sub-alpine environments rely strongly on symbiotic relationships with EMF. A. koreana is an endangered species with a higher host specificity of EMF and climate change vulnerability than T. cuspidata. This study provides insights into the EMF communities, which are symbionts of A. koreana, and our critical findings may be used to restore A. koreana.

Cosmological Origin of Satellites around Isolated Dwarf Galaxies

  • Chun, Kyungwon;Shin, Jihye;Smith, Rory;Kim, Sungsoo S.
    • The Bulletin of The Korean Astronomical Society
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    • v.44 no.2
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    • pp.39.1-39.1
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    • 2019
  • We trace the cosmological origin of satellites around isolated dwarf galaxies using a very high resolution (12 pc/h) cosmological hydrodynamic zoom simulation. To realistically describe the formation and evolution of small-mass stellar satellites, our model includes a full baryonic physics treatment. We find that the mini-halos form objects resembling dwarf galaxies. The majority of their star forming gas is accreted after reionization, thus the survival of a mini-halo's gas to reionization is not an important factor. Instead, the key factor seems to be the ability for a mini-halo to cool its recently accreted gas, which is more efficient in more massive halos. Although the host galaxy is only a dwarf galaxy itself, we find that ram pressure is an efficient means by which accreted mini-halos lose their gas content, both by interacting with hot halo gas but also in direct collisions with the gas disk of the host. The satellites are also disrupted by the tidal forces near the center of the host galaxy. Compared to the disrupted satellites, surviving satellites are relatively more massive, but tend to infall later into the host galaxy, thus reducing the time they are subjected to destructive environmental mechanisms and dynamical friction.

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