• 동의신경정신과학회지
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• 제15권1호
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• pp.65-76
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• 2004

Alzheimer's disease(AD) is a geriatric dementia that is widespread in old ages. In the future AD will be the largest problem in public health service. From old times, much medicines have been used for treatment of dementia, but there is no medicine having obvious effects. AD is one of brain retrogression disease. So we studied on herbal medicine that have a relation for brain retrogression. From old times, in oriental medicine, senile disease such as dementia and AD is treated by exclusion of Tan(痰). But Vascular Dementia(VsD) is due to YuXue(瘀血). So in recent studies, Hua Xue Hua Yu(活血化瘀) medicine is used for precautionary and medical treatment. We studied on the effects for anti-Alzheimer in pCT105-induced neuroblastoma cell lines by Hyeolbuchukeo-tang(HCT). As the results of this study, in HCT group, the apoptosis in the nervous system is inhibited, the repair against the degeneration of Neuroblastoma cells by CT105 expression is promoted. These results indicate that HCT possess strong inhibitory effect of apoptosis in the nervous system and repair effect against the degeneration of neuroblastoma cells by CT105 expression.

• 대한한방내과학회지
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• 제40권5호
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• pp.865-872
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• 2019

Objective: The aim of this case report was to describe the effect of Hyeolgusamhwa-tang (絜矩三和湯 ) on abdominal distension caused by Qi (氣脹) in a patient with functional dyspepsia. Methods: A female Korean patient was treated with Hyeolgusamhwa-tang and acupuncture for 14 days. We observed objective symptoms, such as bloating, nausea, belching, loss of appetite, and heartburn, and we also measured her abdominal circumference. Results: After treatment, her abdominal circumference was decreased from 87 cm to 83.5 cm, and her food intake was improved from the baseline. The other objective symptoms, like general weakness, loss of appetite, abdominal discomfort, and heartburn, were improved or disappeared without any adverse events reported. However, we could not find any significant differences for some symptoms, such as nausea. Conclusions: This case suggests that Hyeolgusamhwa-tang and acupuncture therapy could be effective in reducing functional distension in patients diagnosed with distension caused by Qi (氣脹).

• 대한한방내과학회지
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• 제40권5호
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• pp.920-928
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• 2019

Objectives: After epidural hemorrhage, sequelae may cause cognitive impairments, such as attention, memory, and performance disturbances. This case study reports on the use of traditional Korean medicine in a patient with cognitive impairments after a traumatic epidural hemorrhage. Methods: During the 46-day hospitalization period, traditional Korean medicine treatments, including Sunkihwalhyul-tang-gamibang, Ukgan-san-gajinpibanha Granule, Kyungohk-go, acupuncture, and cupping, were administered. The degree of cognitive impairment was measured based on the Mini Mental State Examination-Korea (MMSE-K), Modified Barthel Index (MBI), and correct answer ratio. Results: After traditional Korean medicine treatment, the MMSE-K score increased from 13 to 19 and the MBI score increased from 63 to 71. The patient's conversations in daily life also proceeded more smoothly than before hospitalization, and the correct answer ratio rose. Conclusion: This case reports the improvement of cognitive impairment after traumatic epidural hemorrhage in response to traditional Korean medicine treatment; further study is needed.

• 대한한방내과학회지
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• 제40권5호
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• pp.929-937
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• 2019

A patients with quadriplegia and a history of pancreatectomy was administered Socheongryong-tang to reduce sputum. The patient's sputum decreased, but a sudden increase in blood sugar was observed. Ephedra is known to stimulate the sympathetic nerves to increase the blood pressure and blood sugar, but in healthy people, changes in blood sugar are not significant due to corrections by hormone regulation. However, this case suggests that ephedra can cause significant blood sugar increases in patients who undergo pancreatectomy or who have diabetes mellitus. Even though ephedra is highlighted for its usefulness in sputum reduction and in weight control, it should be carefully prescribed to patients with diabetes.

• 대한한방내과학회지
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• 제43권2호
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• pp.244-253
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• 2022

Objective: This study reports on the management of a patient with myasthenia gravis (MG) following myasthenic crisis (MC) using Korean medicine. Methods: A 77-year-old Class V MG patient was treated with acupuncture, moxibustion, and Korean herbal medicine. A manual muscle test was used to derive a Medical Research Council (MRC) score and the patient's subjective view of his dyspnea was measured to assess MG symptoms. Results: The MRC grade indicated significant deterioration after 65 days of treatment, although there was no change in the patient's subjective dyspnea assessment. But no other MG or MC complications occurred. Conclusion: This study suggests that Korean medicine could be used for the management of Class V MG patients.

• 대한한방내과학회지
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• 제44권2호
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• pp.244-251
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• 2023

Globus sensation is a continuous, intermittent, non-painful sensation of lumps or foreign substances in the throat. It was reported that 13.7% of patients developed globus sensations after COVID-19 infection. A 73-year-old male patient with a globus sensation after a COVID-19 infection was admitted to the ◯◯ Oriental Medicine Hospital and treated with herbal medicine (Banhahubak-tang, Sosiho-tang). Subjective symptoms of globus sensation were measured with the Numerical Rating Scale (NRS) daily and found to reduce. The effect persisted during his admission. In conclusion, Korean medicine, including Banhahubak-tang, can be effective for patients with globus sensations after COVID-19 infections.

• 동국한의학연구소논문집
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• 제2권2호
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• pp.125-141
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• 1993

• 동국한의학연구소논문집
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• 제2권2호
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• pp.99-124
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• 1993

• 한국경영과학회지
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• 제4권1호
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• pp.103-116
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• 1979

• 동국한의학연구소논문집
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• 제3권
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• pp.355-378
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• 1994