• Journal of Biomedical Engineering Research
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• v.23 no.1
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• pp.39-47
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• 2002

The objective of this study is to provide a Precise form of spatial normalization with affine transformation. The quantitative comparison of the brain architecture across different subjects requires a common coordinate system. For the common coordinate system, not only global brain but also a local region of interest should be spatially normalized. Registration using mutual information generally matches the whose brain well. However. a region of interest may not be normalized compared to the feature-based methods with the landmarks. The hybrid method of this Paper utilizes feature information of the local region as well as intensity similarity. Central gray nuclei of a brain including copus callosum, which is used for feature in Schizophrenia detection, is appropriately normalized by the hybrid method. In the results section. our method is compared with mutual information only method and Talairach mapping with schizophrenia Patients. and is shown how it accurately normalizes feature .

• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.10A
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• pp.962-968
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• 2002

Reliable high-speed data communications over insufficient channel bandwidth is one of the major challenges of harsh wireless environments that push the achievable spectral efficiency far below its theoretical limits. A Quadrature amplitude modulation (QAM) scheme is a userful modulation technique for achieving high data rate transmission without increasing the bandwidth of wireless communication systems. The exact general bit error rate (BER) expression of arbitrary rectangular quadrature amplitude modulation has not yet been derived. In this paper, a generalized closed-form expression for the BER performance of rectangular QAM with Gray code bit mapping is derived and analyzed in the presence of additive white Gaussian noise (AWGN) channel. First we analyze the BER performance of an I-ary PAM scheme. Regular patterns in the k-th bit error probability are observed while developing the EBR expression. From these patterns we provide the exact and general closed-from EBR expression of an I-ary PAM. Then we present a general closed-from expression for BER of an arbitrary IXJ rectangular QAM by considering that this signaling format consists of two PAM scheme, i.e., I-ary and J-ary PAM. A simple approximate BER expression for rectangular QAM is given as well.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.22 no.9
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• pp.2043-2052
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• 1997

The object-oriented coding technique which is one of the coding methods in very low bit rate environment is suitable for videophone image sequence. The selection of source model affect image analysis. In this paper, an image analysis method for the object-oriented coding is presented. The process is composed of changed region detection andmotion estimateion. First, we use the standard deviation of frame difference as thrreshold to extract themoving area. If thesum of gray values in mask is greater than the threshold, the center pixel of the mask is regarded as moving region. After moving is detected in changed region by edge operator, observation point is determined from moving region. The motion is estimated by 6-parameter mapping method with determined observation point. The experimantal resutls show that the proposed method can significantly improve the image quality.

• Journal of Neurogastroenterology and Motility
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• v.24 no.4
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• pp.512-527
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• 2018

This review provides a comprehensive overview of brain imaging studies of the brain-gut interaction in functional gastrointestinal disorders (FGIDs). Functional neuroimaging studies during gut stimulation have shown enhanced brain responses in regions related to sensory processing of the homeostatic condition of the gut (homeostatic afferent) and responses to salience stimuli (salience network), as well as increased and decreased brain activity in the emotional response areas and reduced activation in areas associated with the top-down modulation of visceral afferent signals. Altered central regulation of the endocrine and autonomic nervous responses, the key mediators of the brain-gut axis, has been demonstrated. Studies using resting-state functional magnetic resonance imaging reported abnormal local and global connectivity in the areas related to pain processing and the default mode network (a physiological baseline of brain activity at rest associated with self-awareness and memory) in FGIDs. Structural imaging with brain morphometry and diffusion imaging demonstrated altered gray- and white-matter structures in areas that also showed changes in functional imaging studies, although this requires replication. Molecular imaging by magnetic resonance spectroscopy and positron emission tomography in FGIDs remains relatively sparse. Progress using analytical methods such as machine learning algorithms may shift neuroimaging studies from brain mapping to predicting clinical outcomes. Because several factors contribute to the pathophysiology of FGIDs and because its population is quite heterogeneous, a new model is needed in future studies to assess the importance of the factors and brain functions that are responsible for an optimal homeostatic state.

• The Korean Journal of Nuclear Medicine Technology
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• v.26 no.1
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• pp.33-37
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• 2022

Purpose ¹⁸F-Florbetaben (FBB) Readings are made by visually comparing the signal strengths of gray matter and white matter. We intend to evaluate the usefulness of image analysis by comparing quantified image analysis with readout. Materials and Methods Based on the reading results, 100 patients were divided into a negative scan and a positive scan, and 300 MBq of FBB was injected, and images were taken 90 minutes later for 20 minutes. The equipment was a Discovery 600 (GE Healthcare, MI, USA). Four regions of interest (lateral temporal lobes, frontal lobes, posterior cingulate & precuneus, and parietal lobes) were established based on the amyloid reading standard provided by the manufacturer. For image analysis, SUVratio (SUVr) was calculated by dividing each SUVmean by the cerebellum, and the average SUVr in the entire area was performed. Statistical analysis analyzed the cutoff derivation through ROC Curve, the difference between groups in Independent sample t-test, and the degree of agreement with the reading result through Kappa test. Results The average SUVr cutoff in the entire area was 1.23. Concordance with the read results using cutoff was 95/100 (95%) for negative and 92/100 (92%) for positive. As a result of the t-test, there was a statistically significant difference between the groups (P < 0.05), and the Kappa statistical result showed a high degree of agreement with 0.867 (P < 0.05). Conclusion The results of image analysis were statistically significant and showed a high degree of agreement with the reading results. In addition, FBB image analysis can be viewed by 3D mapping the area where amyloid is accumulated, location estimation is possible, and quantitative analysis results can be viewed in detail. If quantified FBB image analysis is used as an auxiliary indicator, it is thought to be helpful in reading.

• Progress in Medical Physics
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• v.19 no.4
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• pp.269-275
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• 2008

Although MR imaging is generally applicable to depict knee joint deterioration it, is sometimes occurred to mis-read and mis-diagnose the common knee joint diseases. In this study, we employed magnetization transfer ratio (MTR) method to improve the diagnosis of the various knee joint diseases. Spin-echo (SE) T2-weighted images (TR/TE 3,400-3,500/90-100 ms) were obtained in seven cases of knee joint deterioration, FSE T2-weighted images (TR/TE 4,500-5,000/100-108 ms) were obtained in seven cases of knee joint deterioration, gradient-echo (GRE) T2-weighted images (TR/TE 9/4.56/$50^{\circ}$ flip angle, NEX 1) were obtained in 3 cases of knee joint deterioration, In six cases of knee joint deterioration, fat suppression was performed using a T2-weighted short T1/tau inverse recovery (STIR) sequence (TR/TE =2,894-3,215 ms/70 ms, NEX 3, ETL 9). Calculation of MTR for individual pixels was performed on registration of unsaturated and saturated images. After processing to make MTR images, the images were displayed in gray color. For improving diagnosis, three-dimensional isotropic volume images, the MR tristimulus color mapping and the MTR map was employed. MTR images showed diagnostic images quality to assess the patients' pathologies. The intensity difference between MTR images and conventional MRI was seen on the color bar. The profile graph on MTR imaging effect showed a quantitative measure of the relative decrease in signal intensity due to the MT pulse. To diagnose the pathologies of the knee joint, the profile graph data was shown on the image as a small cross. The present study indicated that MTR images in the knee joint were feasible. Investigation of physical change on MTR imaging enables to provide us more insight in the physical and technical basis of MTR imaging. MTR images could be useful for rapid assessment of diseases that we examine unambiguous contrast in MT images of knee disorder patients.

• Economic and Environmental Geology
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• v.47 no.1
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• pp.1-15
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• 2014

The Bobonaro m$\acute{e}$lange is one of the youngest syn-collisional m$\acute{e}$langes, located between the Indo-Australian and Eurasian plates. The m$\acute{e}$lange has formed in association with a collision between the Australian continental margin and the Banda arc initiated in Neogene. The Suai area at the southern part of Timor is a good place to examine the genetic relationship between the m$\acute{e}$lange and other rock sequences because various tectonostratigraphic units coexist in the area. In this study, we present the structural characteristics and spatial distribution of the Bobonaro m$\acute{e}$lange investigated as a part of 1:25K scale geologic mapping in the area, and discuss on the origin of the m$\acute{e}$lange. The Bobonaro m$\acute{e}$lange in the Suai area is composed of unmetamorphosed clay matrix and blocks of various lithologies. The clay matrix mainly is reddish brown or greenish gray in colour, and has scaly texture. Most blocks are allochthonous, but mostly derived from nearby formations. Based on the internal structure and relationship with surrounding rocks, the Bobonaro m$\acute{e}$lange is genetically classified into 1) diapiric m$\acute{e}$lange; 2) tectonic m$\acute{e}$lange; and 3) broken formation. The spatial distribution of the Bobonaro m$\acute{e}$lange indicates that it intruded all pre-collisional units including the lower Australian continental margin unit(Gondwana megasequence) and the Banda arc unit. Taking the field evidences and previous genetic models into consideration, the Bobonaro m$\acute{e}$lange is interpreted to be mainly formed as a diapiric m$\acute{e}$lange originated from Gondwana megasequence, consistently effected by faulting events. This study reflects that diapiric m$\acute{e}$lange is a significant component in recent accretionay-collision belts. It suggests that diapiric process should be considered as a main genetic factor even in ancient m$\acute{e}$lange.