• Title/Summary/Keyword: Genetic Factors

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Genetic Parameters of Milk Yield and Adjustment for Age at Calving in Nili-Ravi Buffaloes

  • Khan, M.S.;Shook, G.E.;Asghar, A.A.;Chaudhary, M.A.;Mcdowell, R.E.
    • Asian-Australasian Journal of Animal Sciences
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    • v.10 no.5
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    • pp.505-509
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    • 1997
  • Data were from four institutional herds and four field data collection centers involved in a progeny testing program for Nili-Ravi buffaloes in Pakistan. The REML with a single trait animal model, employed on 2,353 lactations, from 901 daughters of 66 sires, gave a heritability estimate of 0.18 for milk yield with repeatability (between lactations) of 0.43. Estimated milk yield was highest at 65 months of age for the first parity and 81 months for later parities. Correction factors for age at calving, standardized to 60 months in the second and later parities, were developed.

Restriction-modification system and genetic variability of Xanthomonas oryzae pv. oryzae

  • Choi, Seong-Ho
    • Proceedings of the Korean Society of Plant Pathology Conference
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    • 1995.06b
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    • pp.21-25
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    • 1995
  • ;Bacterial blight caused by Xanthomonas oryzae pv. Olyzae is one of the most important diseases of rice. Host resistance, which relies on single, dominant resistance genes, is the only reliable method to control the disease at present. Pathogenic variation of the bacteria has been shown to follow the deployment of resistance genes in commercial cultivars. Information on the factors and the mechanisms for genetic variation of this pathogen is limited. Further, we have no clear evidence of whether population variability is due to sexual recombination or to variation introduced by mutations or intragenic recombination in a clonally maintained population.(omitted)itted)

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AluI RFLP Analysis of the Calcitonin Receptor Gene in the Korean Athletic Men (한국인 남성 운동 선수군에서 Calcitonin Receptor 유전자의 AluI RFLP 분석)

  • 장대호;황영철;강병용;최성숙;강진양;하남주
    • YAKHAK HOEJI
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    • v.48 no.1
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    • pp.75-81
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    • 2004
  • Bone mineral density (BMD) is influenced by genetic and environmental factors. Among genetic study; calcitonin receptor (CTR) gene is a good candidate influencing the inter-individual difference in BMD because CTR is involved in calcium and bone metabolism. Thus, we investigated the distribution of C1377T polymorphism in the CTR gene among male Korean elite athletic and control groups, respectively and also an association with BMD in lumbar spine and femoral neck. Our results suggested that this polymorphism of CTR gene was not significantly associated with lumbar spine or femoral neck BMDs in the both groups, respectively. However, we found that there was the racial difference in genotype distribution of this polymorphism between Caucasian and Asian populations. Though we could not detect the significant association between C1377T polymorphism of CTR gene and lumbar spine or femoral neck BMDs, further studies using other ethnic groups are necessary to clarify the precise role in BMD of CTR gene.

A Forecasting System for Lung Cancer Sensitivities Using SNP Data

  • Ryoo, Myung-Chun;Kim, Sang-Jin;Park, Chang-Hyeon
    • 한국정보컨버전스학회:학술대회논문집
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    • 2008.06a
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    • pp.191-194
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    • 2008
  • SNP(Single Nucleotide Polymorphism) refers to the difference in a base pair existed in DNAs of individuals. Each of it appears per 1,000 bases in human genome and it enables each gene to defer in junctions, interacts with each other to make different shapes of humans, and produces different disease sensitivities. In this paper, we propose a system to forecast lung cancer sensitivities using SNP data related with the lung cancer. A lung cancer sensitivity forecasting model is also constructed through analysis of genetic and non-genetic factors for squamous cell carcinomas, adeno carcinomas, and small cell carcinomas that may frequently appear in Korean. The proposed system with the model gives the probabilities of the onset of lung cancers in the experimental subjects.

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Genetic Polymorphism of Vascular Endothelial Growth Factor (VEGF C936T) in the Korean Population

  • Kim, Jin-Kyeoung;Oh, Do-Yeun;Kwak, Sun-Young;Han, Jin-Hee;Chung, Young-Sun;Kim, Nam-Keun
    • Animal cells and systems
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    • v.7 no.3
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    • pp.261-264
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    • 2003
  • Leiden), no mutation was detected in either group. Allele frequencies of A2379G and G2391 A mutations were not significantly different between CAD patients and controls. Non-Caucasian populations have a considerably lower factor Ⅴ Leiden allele frequency than Caucasian populations. Thus, it may be due to differences in the genetic background as well as environmental factors.

Genome Architecture and Its Roles in Human Copy Number Variation

  • Chen, Lu;Zhou, Weichen;Zhang, Ling;Zhang, Feng
    • Genomics & Informatics
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    • v.12 no.4
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    • pp.136-144
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    • 2014
  • Besides single-nucleotide variants in the human genome, large-scale genomic variants, such as copy number variations (CNVs), are being increasingly discovered as a genetic source of human diversity and the pathogenic factors of diseases. Recent experimental findings have shed light on the links between different genome architectures and CNV mutagenesis. In this review, we summarize various genomic features and discuss their contributions to CNV formation. Genomic repeats, including both low-copy and high-copy repeats, play important roles in CNV instability, which was initially known as DNA recombination events. Furthermore, it has been found that human genomic repeats can also induce DNA replication errors and consequently result in CNV mutations. Some recent studies showed that DNA replication timing, which reflects the high-order information of genomic organization, is involved in human CNV mutations. Our review highlights that genome architecture, from DNA sequence to high-order genomic organization, is an important molecular factor in CNV mutagenesis and human genomic instability.

Hybrid Fuzzy Controller for High Performance (고성능 제어를 위한 하이브리드 퍼지 제어기)

  • Cho, Joon-Ho;Hwang, Hyung-Soo
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.45 no.5
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    • pp.48-55
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    • 2008
  • In this paper, we propose a hybrid fuzzy controller for high performance. Hybrid fuzzy controller are combined Fuzzy and PID controller. In tuning the controller, the parameters of PID and the factors fuzzy controllers were obtained from the model identification and by using genetic algorithms, respectively. Simulation examples demonstrated a better performance of the proposed controller than conventional ones.

Two Polymorphisms of Interleukin-4 Gene in Korean Adult Periodontitis

  • Kang, Byung-Yong;Choi, Young-Kyu;Choi, Wook-Hwan;Kim, Ki-Tae;Choi, Sung-Sook;Kim, Kyungjae;Ha, Nam-Joo
    • Archives of Pharmacal Research
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    • v.26 no.6
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    • pp.482-486
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    • 2003
  • Adult periodontitis is a multifactorial disease characterized by multple genetic and environmental factors. In view of the importance of interleukin-4 (IL-4) gene as a genetic factor for adult periodontitis, we investigated the relationship between two polymorphisms (-590 C $\rightarrow$ T polymorphism and 70 bp repeat polymorphism) of the human IL-4 gene and adult periodontitis in the Korean population. Genomic DNA was extracted from white blood cells of 32 adult periodontitis patients and 150 normal controls, respectively. There were no significant differences in the allele, genotype and haplotype distributions of two polymorph isms between normal controls and adult periodontitis group. Therefore, our results suggest that IL-4 gene locus contributes little to the interindividual susceptibility for adult periodontitis in Korean population.

The Process for Development of the Optimum Layout Model in Slab Formwork of High-rise Building Construction (초고층 건축공사의 바닥거푸집 최적배치 모델 구축 프로세스 연구)

  • Cha, Minsoo;Kim, Taehoon;Cho, Hunhee;Kang, Kyung-In
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2011.05a
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    • pp.171-172
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    • 2011
  • Formwork accounts for a large proportion of the framework in high-rise construction projects in terms of the duration and cost. Especially, slab formwork has a significant influence on these factors. However, the current selection of formwork method in general contractors depends on the decisions of few experienced engineers, and layout planning of the formwork in specialty contractors requires lots of time by different floor types. As a preliminary study for developing an optimum layout model in slab formwork of high-rise building construction, this study proposes the process of the optimum layout model and determines a fitness function for use of the genetic algorithm aimed at table formwork.

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A Support Model of Optimum Layout Planning of Forms for Improving Constructability of Formwork (거푸집공사 시공성 향상을 위한 거푸집 배치 효율화 지원 모델 - 구조부재 조정을 중심으로 -)

  • Lee, Dongmin;Lim, Hyunsu;Kim, Taehoon;Cho, Hunhee;Kang, Kyung-In
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2013.11a
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    • pp.212-213
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    • 2013
  • The constructability of Formwork has a importantly influence on the duration and cost in a construction project. However, the existing studies on the formwork are mainly focused on a method of construction. Although a layout planning of forms, especially, is an important factors affecting the constructability and cost, it is done by engineers empirically and intuitionally after completion of structure design. Therefore this study suggest a decision support model for optimal formwork layout model based on the rearrangement of structural members by using Genetic Algorithm to improve constructability of formwork.

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