• Journal of the Korean Society of Food Science and Nutrition
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• v.34 no.1
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• pp.42-56
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• 2005

Hyperlipidemia is one of the risk factors for coronary artery disease. Despite of epidemiological evidence that tea consumption is associated with the reduced risk of coronary heart disease, experimental studies designed to show that drinking tea affects blood lipid concentration or oxidative stress have been unsuccessful. The purpose of this study was to investigate whether functional tea (three servings/day) supplement with medical nutrition therapy (MNT) lead to a beneficial outcomes in mildly hyperlipidemic adults. From February to October, 2003, the 43 hyperlipidemic (23 men, 20 women) subjects (total cholesterol$\geq$200 mg/dL or triglyceride$\geq$150 mg/dL) admitted to K Medical Center were studied. Subjects were randomly divided into 3 groups; placebo tea (PT), half dose of functional tea (HFT), full dose of functional tea (FFT). During 12 weeks of study period, the subjects were given placebo or functional tea daily with MNT. Anthropometric measurements, blood chemical analysis including lipid levels, total superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) levels, and dietary assessment were carried out at the beginning and end of experiment. The effects of functional tea were compared with the placebo in randomized clinical trial study. The placebo was prepared to match with the functional tea in color and taste. After the 12 weeks of MNT, the subjects had regular and balanced meal pattern. Consumption of foods high in cholesterol and saturated fat, salty foods, fried foods, and instant foods decreased significantly in all three groups (p<0.05). Intake of energy and cholesterol also decreased (p<0.05). Drinking three servings per day (390 mL/day) of functional tea significantly reduced the levels of blood triglyceride (HFT, 42.5%; FFT, 29.4%), total cholesterol (HFT, 8.5%; FFT, 13.7%), and atherogenic index (HFT, 14.6%; FFT, 21.7%). Whereas no changes were found in the LDL-, HDL-cholesterollevels, and LDL/HDL ratio. Plasma homocysteine (Hcy) concentration decreased significantly (p<0.05) in functional tea groups (HFT, 14.9%; FFT, 14.1%). SOD increased significantly (p<0.05) in HFT (8.3%). GSH-Px increased significantly (p<0.05) in FFT (12.8%). In conclusion, the MNT improved the dietary habits, in addition, functional tea supplement decreased blood lipid levels and Hcy, and increased SOD and GSH-Px levels. These results indicate that functional tea consumption may decrease the risk of cardiovascular disease via improving blood lipid levels and antioxidant status.

• The Korean Journal of Food And Nutrition
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• v.25 no.2
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• pp.308-316
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• 2012

Proper skin care promotes good metabolism and the biological activity of skin, helps maintain the skin in a healthy and beautiful state when combined with nutritional nourishment. Health functional foods are being used for the purpose of enhancing efficient skin care. Health functional foods related to skin care maintain the epidermis, dermal fibroblast layer and subcutaneous tissue that form the skin. Efficient functional foods alleviate the signs of endogenous aging that come with getting older and exogenous aging caused by sunlight. Even though the field of skin care related to health functional foods has received less attention and been the subject of less research compared to functional cosmetics which are developing widely, this area of skin care that maintains and improves the layer of dermal fibroblast through the intake of food, is expected to progress with the commercialization of products in many fields when the related technical research development is galvanized and the related patents are applied for. Research into health functional foods related to skin care in Korea started rather late in comparison to other advanced countries where patents for relevant techniques have been applied for since 1990's together with research conducted on how they might be used for practical purposes. This study used the key words 'skin care, health functional food' to search for Korean patents that have been applied for at the Korean Intellectual Property Office from 1983 to 2011 using the KIPRIS database, in order to help researchers in the related fields by organizing the patented formulas for health functional foods for skin care which have gained attention recently. According to the number of registrations in each industry field, the total number of patents was 1,120 we screened the major patents among them, the field with the largest number was food foodstuff non-alcoholic beverage and preparation or treatment(A23L) with 135, then natural plant medicine & medical supplies and cosmetics(A61K) with 112, microorganisms or enzymes(C12N) with 63, heterocyclic compounds(C07D) with 44, horticulture or cultivation of sea weeds, forestry(A01G) 16 times, listed from the highest to the lowest number of applications. It has been revealed that food, foodstuff, non-alcoholic beverage and preparation or treatment(A23L) was the industry field where the most patents for health functional foods related to skin care were registered.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.10
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• pp.642-651
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• 2017

This study aimed to examine the changes in the health status, social network and satisfaction of caregivers as a result of caregiving using a structural equation model. As a result, it was found that caregiving increased the level of depression and decreased the subjective health status in both men and women. The social network and satisfaction were found to differ according to gender. For the women caregivers, caregiving affected their subjective health status and depression. In the case of the men caregivers, the total effect of caregiving on their subjective health was 1.087(p<.05), while the indirect effect was 0.546(p<.05). Also, caregiving affected the subjective health status of the male caregivers through the functional family network as a mediating factor(0.42, p<.01). The results suggest the necessity to take these gender differences into consideration when discussing the health of caregivers. Also, the functional family network needs to be strengthened to prevent the deterioration of the health status of male caregivers.

• BMB Reports
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• v.38 no.5
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• pp.619-623
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• 2005

The efficacy of chemotherapeutic agents on tumor cells has been shown to be modulated by tumor suppressor gene p53 and its target genes such as Bcl-2 family members (Bax, Noxa, and PUMA). However, various chemotherapeutic agents can induce cell death in tumor cells that do not express the functional p53, suggesting that some chemotherapeutic agents may induce cell death in a p53-independent pathway. Here we showed that etoposide can induce the similar degree of cell death in p53-deficient HCT 116 cells, whereas 5'-FU-mediated cell death is strongly dependent on the existence of functional p53 in HCT 116 cells. Further, we provide the evidence that etoposide can induce the cytochrome c release from isolated mitochondria, and etoposide-induced cytochrome c release is not accompanied with the large amplitude swelling of mitochondria. These data suggest that etoposide can directly induce the mitochondrial dysfunction irrespective of p53 status, and it may, at least in part, account for the p53-independent pathway in cell death induced by chemotherapeutic agents.

• Proceedings of the KIEE Conference
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• 2006.04a
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• pp.297-299
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• 2006

Many distributed applications is developed in various environment such as operating system, software platform. So, they exhibit different types of system behavior, status, during the course of their operation. Each such behavior may have different functional and non-functional requirements. Therefore, many distributed application need to fault-tolerance solution. Personal robot provide various service or application. Because personal robot has many application or service, it need to fault-tolerance architecture. A flexible architecture is required to provide dependability. In this paper, it is suggested a fault-tolerant architecture for module-based personal robot with module fault-tolerance, service fault-tolerance.

• Progress in Medical Physics
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• v.30 no.2
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• pp.39-48
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• 2019

Deep learning has been applied to various medical data. In particular, current deep learning models exhibit remarkable performance at specific tasks, sometimes offering higher accuracy than that of experts for discriminating specific diseases from medical images. The current status of deep learning applications to molecular imaging can be divided into a few subtypes in terms of their purposes: differential diagnostic classification, enhancement of image acquisition, and image-based quantification. As functional and pathophysiologic information is key to molecular imaging, this review will emphasize the need for accurate biomarker acquisition by deep learning in molecular imaging. Furthermore, this review addresses practical issues that include clinical validation, data distribution, labeling issues, and harmonization to achieve clinically feasible deep learning models. Eventually, deep learning will enhance the role of theranostics, which aims at precision targeting of pathophysiology by maximizing molecular imaging functional information.

• Language and Information
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• v.5 no.1
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• pp.55-71
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• 2001

One of the controversial issues in English locative inversion (LI) construction( e. g. Under the tree sat a woman) has been the functional status of preverbal PP and postverbal NP, i.e. whether they are a subject, a complement, or filer (topic) Based on the distributional parallelisms between the PP and NP on the one hand and an ordinary subject and filler on the other this paper proposes that the PP has a dual function as a subject and filler, while the NP also has some subject properties that the PP does not have These mixed functional properties are analyzed in the theory of HPSG expecially with the versions recently developed by Sag(1997) Manning and Sag(1999) and Ginzburg and Sag(to appear). This analysis claims that the LI construction needs to satisfy two general, independent constraints head-subject- phrase and head-filler-phrase. This position suggests that the English LI construction is an instance of the peripheral phenomena whose construction specific constraint is inherited from more general core constraints. (Dongseo University)

• Phonetics and Speech Sciences
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• v.7 no.2
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• pp.119-129
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• 2015

This paper investigates the status of the merger between the mid front unrounded vowels ㅔ[e] and ㅐ[${\varepsilon}$] in contemporary Korean. Our analysis is based on a balanced corpus of production and perception data from young subjects from three dialectal areas (Seoul, Daegu and Gwangju). Except for expected gender differences, the production data display no difference in the realization of these vowels, in any of the dialects. The perception data, while mostly in line with the production results, show that Seoul females tend to better discriminate the two vowels in terms of perceived height: vowels with a lower F1 are more likely to be categorized as ㅔ by this group. We then investigate the possible causes of this merger: based on an empirical study of transcribed spoken Korean, we show that the pair of vowels ㅔ/ㅐ has a very low functional load. We argue that this factor, together with the phonetic similarity of the two vowels, may have been responsible for the observed merger.

• Journal of Digital Convergence
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• v.7 no.4
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• pp.57-65
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• 2009

This study explored the current supply status on Contents Technology R&D(research and development) and friendly function Game Industry targeting to elderly consumers. The game contents including the functional components are categorized the sixth category of CT R&D's fundamental planning. The function game targeting to elderly focused on emotional and physical recovering to barrier, user friendliness, simplicity and certainty of game performance. The purpose of game participation are health, well-being, psychological wellness and communication. The functional game consisted of various version procedure by socio-demographic, the accessibility to game media and device.

• The Journal of the Convergence on Culture Technology
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• v.1 no.1
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• pp.87-90
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• 2015

Find out about the Status and future direction of the latest special lighting, through the installation of special lighting for worship practices used in religious institutions. by applying the LED installation practices, Looked for in the past with other functional features. When replacing halogen lighting with LED lighting, According to the illumination economic evaluation, Confirmed, to be an approximately 25% reduction in the applicable. with functional factors of LED luminaires the feed will be applied more in the future.