• IMMUNE NETWORK
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• v.10 no.1
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• pp.5-14
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• 2010

Background: There have been several reports describing the capability of ginseng extracts as an adjuvant. In this study, we tested if ginsan, a polysaccharide extracted from Panax ginseng, was effective in enhancing antibody response to orally delivered Salmonella antigen. Methods: Ginsan was treated before oral salmonella antigen administration. Salmonella specific antibody was determined by ELISA. mRNA expression was determined by RT-PCR. Cell migration was determined by confocal microscopy and flow cytometry. COX expression was detected by western blot. Results: Ginsan treatment before oral Salmonella antigen delivery significantly increased both secretory and serum antibody production. Ginsan increased the expression of COX in the Peyer's patches. Various genes were screened and we found that CCL3 mRNA expression was increased in the Peyer's patch. Ginsan increased dendritic cells in the Peyer's patch and newly migrated dendritic cells were mostly found in the subepithelial dome region. When COX inhibitors were treated, the expression of CCL3 was reduced. COX inhibitor also antagonized both the migration of dendritic cells and the humoral immune response against oral Salmonella antigen. Conclusion: Ginsan effectively enhances the humoral immune response to orally delivered antigen, mediated by CCL3 via COX. Ginsan may serve as a potent vaccine suppliment for oral immunization.

• Fire Science and Engineering
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• v.25 no.5
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• pp.32-38
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• 2011

Amphibious possible, and good fuel economy, so as leisure and transport has increased the use of hovercraft. Fire started in Korea, the prevalence is increasing in demand as the trend has been increasing steadily. In this paper, the hovercraft's forward and backward direction can be controlled in order to free the reverse bucket control system was developed. Control due to development by promoting the flow of air and turn right, turn left and easy to reverse the life-saving and stable at high speed, etc. has made possible the operation of hovercraft. The controller for the stability and fast response Fuzzy-PID method was used. To prove the validity of the proposed controller in Matlab simulation and the actual delivery at the firehouse, built into a model for the demonstration test was performed.

• JSTS:Journal of Semiconductor Technology and Science
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• v.13 no.4
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• pp.395-401
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• 2013

In-situ optical emission spectroscopy (OES) is employed for leak detection in plasma etching system. A misprocessing is reported for significantly reduced silicon etch rate with chlorine gas, and OES is used as a supplementary sensor to analyze the gas phase species that reside in the process chamber. Potential cause of misprocessing reaches to chamber O-ring wear out, MFC leaks, and/or leak at gas delivery line, and experiments are performed to funnel down the potential of the cause. While monitoring the plasma chemistry of the process chamber using OES, the emission trace for nitrogen species is observed at the chlorine gas supply. No trace of nitrogen species is found in other than chlorine gas supply, and we found that the amount of chlorine gas is slightly fluctuating. We successfully found the root cause of the reported misprocessing which may jeopardize the quality of thin film processing. Based on a quantitative analysis of the amount of nitrogen observed in the chamber, we conclude that the source of the leak is the fitting of the chlorine mass flow controller with the amount of around 2-5 sccm.

• Nuclear Engineering and Technology
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• v.34 no.5
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• pp.421-432
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• 2002

As one of the advanced design features of the APR1400, direct vessel injection (DVI) system is being considered instead of conventional cold leg injection (CLI) system. It is known that the DVI system greatly enhances the reliability of the emergency core cooling (ECC) system. However, there is still a dispute on its performance in terms of water delivery to the reactor core during the reflood phase of a large-break loss-of-coolant accident (LOCA). Thus, experimental validation is under progress. In this paper, test results of direct ECC bypass performed in the steam-water test facility tailed MIDAS (Multi-dimensional Investigation in Downcomer Annulus Simulation) are presented. The test condition is determined, based on the preliminary analysis of TRAC code, by applying the ‘modified linear scaling method’with the l/4.93 length scale . From the tests, ECC direct bypass fraction, steam condensation rate and information on the flow distribution in the upper annulus downcomer region are obtained.

• Journal of Institute of Control, Robotics and Systems
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• v.4 no.6
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• pp.802-810
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• 1998

The purpose of this study is to find the analytic solution of determining the optimal capacity of processes and storages to meet the product demand. Recent trend to reduce product delivery time and to provide high quality product to customer requires the increasing capacity of storage facilities. However, the cost of constructing and operating storage facilities is becoming substantial because of increasing land value, environmental and safety concern. Therefore, reasonable decision making about the capacity of processes and storages is important subject for industries. The industrial solution for this subject is to use the classical economic lot sizing method, EOQ(Economic Order Quantity) model, trimmed with practical experience but the unrealistic assumption of EOQ model is not suitable for the chemical plant design with highly interlinked processes and storages. This study, a first systematic attempt for this subject, clearly overcomes the limitation of classical lot sizing method. The superstructure of the plant consists of the network of serially and/or parallelly interlinked processes and storages. A novel production and inventory analysis method, PSW(Periodic Square Wave) model, is applied. The objective function of optimization is minimizing the total cost composed of setup and inventory holding cost. The advantage of PSW model comes from the fact that the model provide a set of simple analytic solution in spite of realistic description of material flow between process and storage. The resulting simple analytic solution can greatly enhance the proper and quick investment decision for the preliminary plant design confronting diverse economic situation.

• Architectural research
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• v.15 no.3
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• pp.167-174
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• 2013

Due to increasing competition of construction companies, it is required to optimize the management of construction projects and "lean" concepts are rapidly spreaded in construction industry. Steel work accounts for a large proportion in construction work, and a variety of attempts to efficiently perform steel work has currently made. And since rebar (Engineer-to-Order) can be engineered through design once order is placed, it gives the great impact on construction, thus, entire management is required. The purpose of this study is to present the method to increase the efficiency of field processing method of steel work in terms of lean construction. Once we examine process of steel work and identify the flow, we would like to analyze which processes should be improved through value analysis approach and present the improvement plans. Also, this study examines cases of field processing and factory processing, and it identifies the waste factors in the procurement process. Finally, this study would like to present the result of analysis from the perspectives of value. The rebar delivery process is divided into several steps and the duration of every step is surveyed. Using duration data, VAT (Value added time) can be calculated for analyzing the efficiency of the process.

• Journal of Communications and Networks
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• v.13 no.3
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• pp.277-285
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• 2011

Real-time multimedia streaming over the Internet is rapidly increasing with the popularity of user-created contents, Web 2.0 trends, and P2P (peer-to-peer) delivery support. While many homes today are broadband-enabled, the quality of experience (QoE) of a user is still limited due to frequent interruption of media playout. The vulnerability of TCP (transmission control protocol), the popular transport-layer protocol for streaming in practice, to the packet losses, retransmissions, and timeouts makes it hard to deliver a timely and persistent flow of packets for online multimedia contents. This paper presents TCP-real-time online multimedia environment (ROME), a novel transport-layer framework that allows the establishment and coordination of multiple many-to-one TCP connections. Between one client with multiple home addresses and multiple co-located or distributed servers, TCP-ROME increases the total throughput by aggregating the resources of multiple TCP connections. It also overcomes the bandwidth fluctuations of network bottlenecks by dynamically coordinating the streams of contents from multiple servers and by adapting the streaming rate of all connections to match the bandwidth requirement of the target video.

• Clinical and Experimental Pediatrics
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• v.58 no.7
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• pp.270-273
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• 2015

Legg-Calve-Perthes (LCP) disease is characterized by idiopathic avascular osteonecrosis of the epiphysis of the femur head. The main factor that plays a role in the etiology of the disease is decreased blood flow to the epiphysis. Many predisposing factors have been suggested in the etiology of LCP disease, and most have varying degrees of effects. Here we present the case of a boy aged 4 years and 10 months with complaints of short stature and a diagnosis of multiple hypophyseal hormone deficiency, in whom LCP disease and difficult birth-related pituitary stalk interruption syndrome were identified by anamnesis. The present case revealed that LCP disease and hypophyseal hormone deficiency could be secondary to difficult birth and that LCP disease could be secondary to insulin-like growth factor 1 deficiency. Additionally, to the best of our knowledge there is no published case on the relation between LCP disease and insulin-like growth factor 1 deficiency. Therefore, we believe that this case is worthy of presentation.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2006.05a
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• pp.81-82
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• 2006

Conveyor-type transporters have been widely used as a typical delivery system of semi-conductor, FPD and other IT-related products. However, as the IT-product is getting larger in size and higher in resolution, several problems are caused by mechanical contacts between the transporter and target object. In this context, recently, lots of efforts are being devoted for development of various contact-free handling systems to get rid of deffets and oil contaminations. The objectives of this paper are to characterize suspension mechanisms and to investigate air flow effects on air levitation transport system. For this purpose, a series of CFD analyses were carried out and the simulation data showed a good agreement with the corresponding experimental ones. It is anticipated that the promising result can be used as a basis for concept design of the transport system.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.6 no.3
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• pp.886-905
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• 2012

Set-top Box (STB) has evolved from being a device just sitting on top of a TV shelf to a device providing a gateway to the Internet for a home network, receiving services from multiple content providers, and enabling and ensuring Quality of Service (QoS) for the streaming media. IP Multimedia Subsystem (IMS), with its promise to provide a converged access network for multimedia service delivery (such as Triple play & Quadruple play services), has to guarantee QoS support. To enable QoS in IMS-based networks, we have designed a set-top box which provides feedback to the service provider to ensure end-to-end QoS. Our set-top box is designed to provide virtual platforms such that it can support multiple service providers. Each service provider is able to manage its own multimedia streams and ensures the desired network performance for each flow. The set-top box also works as a Home Gateway and provides end-to-end QoS support to the client nodes.