• Asian-Australasian Journal of Animal Sciences
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• v.31 no.1
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• pp.138-148
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• 2018

Objective: Fusarium mycotoxins deoxynivalenol (DON) and zearalenone (ZEN), common contaminants in the feed of farm animals, cause immune function impairment and organ inflammation. Consequently, the main objective of this study was to elucidate DON and ZEN effects on the mRNA expression of pro-inflammatory cytokines and other immune related genes in the kidneys of piglets. Methods: Fifteen 6-week-old piglets were randomly assigned to three dietary treatments for 4 weeks: control diet, and diets contaminated with either 8 mg DON/kg feed or 0.8 mg ZEN/kg feed. Kidney samples were collected after treatment, and RNA-seq was used to investigate the effects on immune-related genes and gene networks. Results: A total of 186 differentially expressed genes (DEGs) were screened (120 upregulated and 66 downregulated). Gene ontology analysis revealed that the immune response, and cellular and metabolic processes were significantly controlled by these DEGs. The inflammatory stimulation might be an effect of the following enriched Kyoto encyclopedia of genes and genomes pathway analysis found related to immune and disease responses: cytokine-cytokine receptor interaction, chemokine signaling pathway, toll-like receptor signaling pathway, systemic lupus erythematosus (SLE), tuberculosis, Epstein-Barr virus infection, and chemical carcinogenesis. The effects of DON and ZEN on genome-wide expression were assessed, and it was found that the DEGs associated with inflammatory cytokines (interleukin 10 receptor, beta, chemokine [C-X-C motif] ligand 9, CXCL10, chemokine [C-C motif] ligand 4), proliferation (insulin like growth factor binding protein 4, IgG heavy chain, receptor-type tyrosine-protein phosphatase C, cytochrome P450 1A1, ATP-binding cassette sub-family 8), and other immune response networks (lysozyme, complement component 4 binding protein alpha, oligoadenylate synthetase 2, signaling lymphocytic activation molecule-9, ${\alpha}$-aminoadipic semialdehyde dehydrogenase, Ig lambda chain c region, pyruvate dehydrogenase kinase, isozyme 4, carboxylesterase 1), were suppressed by DON and ZEN. Conclusion: In summary, our results indicate that high concentrations of DON and ZEN suppress the inflammatory response in kidneys, leading to potential effects on immune homeostasis.

• Food Engineering Progress
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• v.13 no.4
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• pp.269-274
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• 2009

The main objective of this study was to establish optimum condition of wet grinding process for manufacturing microparticulated seaweed calcium. Process parameters such as concentration of forming agent, rotor speed, bead size, feed rate, and grinding time were adapted during wet-grinding of seaweed calcium. The particle size range of the raw seaweed calcium was 10-20 $\mu$m. The calcium particles were reduced to under 1 $\mu$m as nano scale after grinding. Gum arabic was suitable for forming agent and 5%(w/v) concentration was the most effective in grinding efficiency. A wet-grinding process operated at 4,000 rpm rotor speed, 0,4 mm bead size, and 0.4 L/hr feeding rate, respectively, produced less than 600 mm(>>90%)-sized particles. In batch systems, 8 cycles of grinding showed higher efficiency, but 20 min of grinding time in continuous processing was more efficient to reduce particle size than the batch processing. Based on the result, the optimum conditions of the wet grinding process were established: operation time of 20 minutes, rotor speed of 4,000 rpm, bead size of 0.4 mm, feed rate of 40 mL/min and 30% mixing ration with water. The size of the resulting ultra fine calcium particles ranged between 40 and 660 mm.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2011.11a
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• pp.721-724
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• 2011

A system to pressurize propellants stored in propellant tanks is necessary to feed liquid-propellants into combustion devices at the required pressure and flowrate without having cavitation in turbo-pumps. A pressurization system can be categorized into pre-pressurization stage and main-pressurization stage. This report is regarding to a main-pressurization system. Pressurization methods for propellant tanks are divided into pressurant gas generating method and pressurant gas feeding method. One of pressurant gas generating methods uses the vaporized oxygen gas from cryogenic liquid oxygen and non-flammable gas. In this report, both advantages and disadvantages for pressurization methods and types of pressurization systems are compared. Especially the characteristics and principle of pressurization system using impulsive control strategy applied in launch vehicles are introduced. Additionally the structure, schematics, and specifications of heat exchanger, which is one of main units in pressurization system are also discussed. This paper can be utilized to generate the conceptual requirements and to design preliminary configuration of pressurization system during the development of launch vehicle.

• The Journal of Bigdata
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• v.5 no.2
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• pp.145-153
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• 2020

This study was conducted with funding from the government (Ministry of Agriculture, Food and Rural Affairs) in 2018 with support from the Agricultural, Food, and Rural Affairs Agency, 318069-03-HD040, and is based on artificial intelligence-based HPAI spread analysis and patterning. Highly Pathogenic Avian Influenza (HPAI) is coming from abroad through migratory birds, but it is not clear exactly how it spreads to farms. In addition, it is assumed that the main cause of the spread is the vehicle, but the main cause of the spread is not exactly known. However, it is necessary to analyze the relationship between the vehicles and the facilities at the farms where they occur, as the type of vehicles that visit the farms most frequently is between farms and facilities, such as livestock transportation and feed transportation. In this paper, based on the Korea Animal Health Integrated System (KAHIS) data provided by Animal and Plant Quarantine Agency, the main cause of HPAI virus transfer is to be confirmed between vehicles and facilities.

• Korean Journal of Veterinary Service
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• v.22 no.4
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• pp.349-356
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• 1999

Type C botulism was broken out in cattle at Pochun country, Kyonggi in Korea. The main cause was on the feed of fermented food contaminated with Clostridium botulinum. It was supposed to be contaminated with C botulinum during producing the fermented food because of either using contaminated food residues or adding contaminated additive materials like sausage. One hundred and twenty out of 642 cattle in 11 farms showed typical botulism symptoms and 95 among them died. The incubation period was from 2 to 14 days and the average incubation period was 8 days. The mortality in this case was 18.3%.

• Proceedings of the Korean Fiber Society Conference
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• 2003.04a
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• pp.402-403
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• 2003

Garment manufacture represents the final stage of processing a finished fabric. The main task of the garment manufacturer is to produce shell structures out of flat fabrics to match the shape of the human body, and the most acceptable means of joining textile materials for apparel use is by sewing. On the sewing process, the bottom layer is pushed forward by the feed-dog, but the presser foot tends to retard the passage of the top layer. Since the friction between the layers is low, is possible that the components will move out of phase and pucker. (omitted)

• Journal of Biosystems Engineering
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• v.8 no.2
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• pp.86-98
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• 1983

본 연구는 미국의 사료공장 중 주종을 이루고 있는 형식을 분석하여 일반적인 Model로 개발하였고 이 Model을 설계할 수 있는 Computer Program을 개발하였다. Model에 적용된 규모는 10ton/hr로부터 50ton/hr이었고 종류는 돼지 및 닭 사료공장과 완전히 pellet화된 소 사료공장이었다. 개발된 Computer Program은 1개의 Main Program과 3개의 Subprogram으로 구성되어 있고 29개의 Input data을 사용하게 되어 있다. 이 Computer Program의 output은 다음과 같다. 1. 공장의 Dimension 2. 곡물저장 및 원료 bin의 수량 및 규모 3. 각 기계의 규모 및 성능 4. 총 작업시간 및 전기 소요량 위와같은 사료공장의 일반화 된 Model 및 이를 설계하기 위한 Computer Program은 사료 생산의 소요동력, 노동력 및 투자자본까지 추정할 수 있게 하였으며 이 분야에서 학문적으로 처음 시도하여 본 것이다.

• 제어로봇시스템학회:학술대회논문집
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• 1997.10a
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• pp.1520-1523
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• 1997

A rigorous dynamic simulation was performed in binary gas mixture H$_{2}$/CO (70:30 vol.%) to determinate start-up operating conditions of PSA(Pressure Swing Adsorption) processes. The rigorous dynamic model for the PSA process contains an Ergun equation for expressing the pressure drop in a bed, and valve equations to compute the boundary pressure change of the bed. As the result of the continuous dynamic simulation of 100 operating cyles in various initial conditions, the unsteady-state appeared in the early period and the cyclic steady-state came out about 20th cycle in feed condition and vaccum condition, and 30th cycle in pure H$_{2}$ condition. As time goes by valve equations made change the pressure at each end of the bed in ressurization, countercurrunt-depressurization and pressure equalization steps. The H$_{2}$ purity and the recovery is 99.99% and 86.73% respectively, which is slightly higher than the experimental data. Main contributiion of this study includes supplying fundamental technologies of handling combined variables PSA processes by developing rigorous models.

• IE interfaces
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• v.15 no.3
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• pp.308-315
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• 2002

This study presents the web based cutting parameter selection system using Group Technology (GT). The GT is basically applied to classify and code the work material and cutting process which are main factors to affect cutting parameter selection. The proposed system has been designed to electronically select proper cutting conditions based on the stored GT database. The existing approaches used in most small and medium sized companies are basically to use manufacturing engineer's experience or to find the recommended values from the manufacturing engineers handbook. These processes are often time consuming and inconsistent, especially when a new engineer is involved. Consequently, the proposed system could automatically and consistently generate the proper cutting conditions (feed, depth of cut, and cutting speed) as soon as relatively simple data input is given thanks to the classified GT database.

• The Transactions of the Korean Institute of Electrical Engineers
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• v.40 no.1
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• pp.120-127
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• 1991

The purpose of this study is to develop a fault detection and diagnosis scheme that can monitor process fault and instrument fault of a steam generator. The suggested scheme consists of a Kalman filter and two bias estimators. Method of detecting process and instrument fault in a steam generator uses the mean test on the residual sequence of Kalman filter, designed for the unfailed system, to make a fault decision. Once a fault is detected, two bias estimators are driven to estimate the fault and to discriminate process fault and instrument fault. In case of process fault, the fault diagnosis of outlet temperature, feed-water heater and main steam control value is considered. In instrument fault, the fault diagnosis of steam genrator's three instruments is considered. Computer simulation tests show that on-line prompt fault detection and diagnosis can be performed very successfully.