• Journal of the Korean Geotechnical Society
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• v.29 no.11
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• pp.29-47
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• 2013

This study undertook research on the sections of 90 harbor structures which applied a pile-type soil improvement using the soil-cement pile and then, determined the minimum replacement rate for each section, showing sufficient stability in all relevant studies including numerical analysis. The reliability of the numerical analysis was verified by a centrifuge model test. As a result of the study, it was revealed that when the foundation soil is too soft ($s_u$ = under 15 kPa), it is unsuitable to apply a pile-type ground improvement to a soil improvement regardless of types of super structures. And a pile-type soil improvement was found to be suitable for a harbor structure with the relative stiffness ratio (n) of less than 50~75 at a maximum and the 2~3 MPa strength of the soil-cement pile. Furthermore the governing factor for the minimum replacement rate for the pile-type soil improvement was turned out to be the allowable horizontal displacement. Therefore, the primary review to see the applicability of the pile-type soil improvement requires the evaluation of horizontal displacements.

• Resources Recycling
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• v.16 no.6
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• pp.20-27
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• 2007

This paper presents a detailed experimental study on the durability properties of mortar matrix made with two kind of recycled fine aggregates(RAA, RAB) and five replacement levels (0, 25, 40, 75 and 100) of the recycled fine aggregates as a partial replacement of natural fine aggregate (NA). The durability properties of mortar matrix was evaluated using compressive strength, chloride ion ingress, sulfate attack and carbonation. The test results indicated that the water absorption and Adhered mortar of the recycled fine aggregate was a major factor controlling durability properties. Hereafter, when using built recycled fine aggregate is expected, appropriate removal Adhered mortar and reasonable replacement ratio of recycled fine aggregates was 25% weight of cement are advised to apply to the concrete materials.

• Journal of the Korea Society of Computer and Information
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• v.25 no.2
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• pp.1-10
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• 2020

In this paper, we propose an efficient disk buffer replacement policy which improves hit ratio and reduces writing operations of flash based storages. The flash based storage has many advantages, including a small form factor, non-volatility and high reliability, but there are problems caused by own limitations, like not-in-place update, short life cycle and asymmetric I/O latencies. To redeem these problems, this paper proposes the write weighted probability of reference(2WPR) policy. 2WPR policy predicts re-referencing probability and calculates localities of each page. Furthermore, by weighting write operations to every pages, 2WPR can reduce write operations to flash based storage. In addition, we can improve the performance with higher hit ratio and reduce the number of write operations and consequently shorten the latencies of each operation. The results show that our policy provides improvements of up to 10% for the hit ratio with the reduction of up to 5% for the flash writing operation compared with other policies.

• Journal of Microbiology
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• v.41 no.4
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• pp.340-344
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• 2003

The group I intron from Tetrahymena thermophila has been demonstrated to employ splicing reactions with its substrate RNA in the trans configuration. Moreover, we have recently shown that the transsplicing group I ribozyme can replace HCV-specific transcripts with a new RNA that exerts anti-viral activity. In this study, we explored the potential use of RNA replacement for cancer treatment by developing trans-splicing group I ribozymes, which could replace tumor-associated RNAs with the RNA sequence attached to the 3' end of the ribozymes. Thymidine phosphorylase (TP) RNA was chosen as a target RNA because it is known as a valid cancer prognostic factor. By performing an RNA mapping strategy that is based on a trans-splicing ribozyme library, we first determined which regions of the TP RNA are accessible to ribozymes, and found that the leader sequences upstream of the AUG start codon appeared to be particularly accessible. Next, we assessed the ribozyme activities by comparing trans-splicing activities of several ribozymes that targeted different regions of the TP RNA. This assessment was performed to verify if the target site predicted to be accessible is truly the most accessible. The ribozyme that could target the most accessible site, identified by mapping studies, was the most active with high fidelity in vitro. Moreover, the specific trans-splicing ribozyme reacted with and altered the TP transcripts by transferring an intended 3' exon tag sequence onto the targeted TP RNA in mammalian cells with high fidelity. These results suggest that the Tetrahymena ribozyme can be utilized to replace TP RNAs in tumors with a new RNA harboring anti-cancer activity, which would revert the malignant phenotype.

• The Korean Journal of Food And Nutrition
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• v.32 no.1
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• pp.50-60
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• 2019

The importance and satisfaction with the purchasing characteristics and choice attribute of home meal replacement (HMR) products for consumers aged between 20 and 40, or over 50. In addition to identify the factors that must be first considered in the development of HMR products importance-performance analysis. 791 consumers aged between 20 and 40, or over 50, living in Seoul have experience in purchasing HMR participated in the survey. The survey consisted of four sections: The purchasing characteristics of HMR, the importance and satisfaction with HMR choice attribute, and general questions. T-tests and IPA were conducted to compare the groups of consumers aged between 20 and 40, or over 50. The factor analysis show the following results: 0.899 for "convenience", 0.094 for "hygiene", 0.871 for "quality", 0.834 for "taste", and 0.822 for "price". The average score of the importance of the choice attribute when purchasing HMR products 3.50. For consumers aged between 20 and 40, the score 3.49. For consumers over 50, the score 3.52. There is a significant difference "hygiene (p<0.001)", "quality (p<0.05)", and "price (p<0.05)". For consumers aged between 20 and 40, the score 3.72. For consumers over 50, the score was 3.78. There a significant difference only in "hygiene (p<0.05)". The results of the IPA demonstrate that the categories that belong to "Focus here" are "new HMR products" and "diverse HMR products" for all consumers aged between 20 and 40 and over 50. Hence, food companies should endeavor to develop new and diverse HMR products first.

• Journal of Chest Surgery
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• v.54 no.3
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• pp.191-199
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• 2021

Background: Tracheal replacement is a challenge for thoracic surgeons due to stenosis in the trachea-prosthesis anastomosis. We propose that stenosis occurs due to fibrosis as a result of an abnormal healing process, characterized by an increased expression of wound healing growth factors (vascular endothelial growth factor [VEGF], survivin, and CD31), which promote angiogenesis and decrease apoptosis. We analyzed the immunoreactivity of VEGF, survivin, CD31, and caspase-3 in the development of fibrotic stenosis in prosthetic tracheal replacement. Methods: Fourteen dogs were operated on: group I (n=7) received a 6-ring cervical tracheal segment autograft, while in group II (n=7), a 6-ring segment of the cervical trachea was resected and tracheal continuity was restored with a Dacron prosthesis. The follow-up was 3 months. Immunoreactivity studies for VEGF, survivin, CD31, and caspase-3 were performed. A statistical analysis was done using the Wilcoxon signed rank test. Results: Four animals in group I were euthanized on the 10th postoperative day due to autograft necrosis. Three animals completed the study without anastomotic stenosis. Moderate expression of VEGF (p=0.038), survivin (p=0.038), and CD31 (p=0.038) was found. All group II animals developed stenosis in the trachea-prosthesis anastomotic sites. Microscopy showed abundant collagen and neovascularization vessels. Statistically significant immunoreactive expression of VEGF (p=0.015), survivin (p=0.017), and CD31 (p=0.011) was observed. No expression of caspase-3 was found. Conclusion: We found a strong correlation between fibrosis in trachea-prosthesis anastomoses and excessive angiogenesis, moderate to intense VEGF, CD31, and survivin expression, and null apoptotic activity. These factors led to uncontrolled collagen production.

• Journal of the Korean GEO-environmental Society
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• v.8 no.3
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• pp.19-25
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• 2007

Stone columns is the ground improvement method which composed of compacted gravel or crushed stone inserted into the soft ground consisting of loose sand and clay. There are many difficulties in quantitative analysis of soil-pile interaction because settlement behavior of stone columns is affected by various parameters. In this study, various parameters of behavior of end-bearing group piles are investigated by load tests. Finally, the improved characteristics of soft ground and the influence of design parameters are investigated in this study using PR (performance ratio) value. From the PR value calculation and test results, we know that settlement behavior of stone columns is affected by area replacement ratio of composite ground, diameter of column rather than embedment ratio and mat.

• The Journal of Industrial Distribution & Business
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• v.11 no.10
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• pp.17-25
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• 2020

Purpose: The purpose of this study is to narrow the target down to college students representing single-person households to identify the main attributes of their choice of Home Meal Replacement(HMR) and to look at the impact on satisfaction and repurchase intentions. Research design, data and methodology: An online survey was conducted for consumers who purchased HMR products at least once and a total of 264 questionnaires were used for demonstration analysis. The collected data have verified for validity and reliability between measurement variables through exploratory factor analysis and reliability analysis. Results: As a result, curiosity, economy, safety, and brand, which are HMR selection attributes that university students' value, have a significant impact on satisfaction, and satisfaction has a significant impact on the intention of repurchase, a variable of behavior. In addition, the adjustment effect of health value pursuit was significant only in safety attributes. Conclusions: This study divided the target group to examine what the HMR selection attributes of single-person college students are, the main consumer of HMR, and how selective attributes affect satisfaction and willingness to repurchase. In the process, we wanted to find out if there was a moderating effect on the health-oriented values in the dietary lifestyle.

• Journal of Nutrition and Health
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• v.40 no.7
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• pp.650-657
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• 2007

The survey was conducted to investigate athletes# beverage drinking pattern and their knowledge concerning hydration and fluid replacement. The subjects were 371 collegiate athletes (235 males and 136 females) in Seoul and Daejun area. The mean age of the athletes was 20.44 y. The prevalence of sports drink use among subjects at ordinary time, after training, and after competition were 9.0%, 17.1%, and 57.3% respectively. Primary source of sports drink information were advertisement (57.3%), friends or colleagues (14.9%), and coaches (7.0%) The purchase of sports drink was done by athletes themselves (76.0%) and coaches (22.6%). The most influential factor in choice of sports drink was taste (61.5%), brand name (15.1%), composition (12.4%), and advertisement (6.7%) However, only 9.5% of the subjects answered they know well about the sports drink they are drinking. To the 15 questions to survey the nutritional knowledge about fluid and intake of sports drink, subjects responded correctly to 58.47%. Their sex or experiences of nutrition education didn#t affect to their knowledge. As the result, the prevalence of collegiate athletes# sports drink use was high but their knowledge about it was not sufficient. These results suggest that an effective and practical nutrition education for adequate hydration and choice of sports drink for atheletes should be considered.

• Journal of Chest Surgery
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• v.26 no.3
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• pp.196-203
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• 1993

Fourty-five cases of operation were performed for the correction of tricuspid regurgitation [TR] in Pusan National University Hospital between 1982 and 1991.The mean age of the patients was 32.6 years and female was dominant[M:F=1:2.2].Isolated tricuspid regurgitation was rare and 43 patients underwent concomitant other valvular operation including mitral valve replacement. Functional cause was in 39 cases and organic lesions were found in 6 cases. Operative methods were Kay annuloplasty[29], De Vega annuloplasty[12], and tricuspid valve replacement[4]. Ring annuloplasty was not performed. Operative mortality rate was 11.1%[5/45] and late mortality rate was 6.7%[2/30]. The tricuspid valve surgery itself was not a serious risk factor for hospital death and no heart block nor thrombosis was complicated. By echocardiogram early[within 30 days] and late [mean:4.9years] changes of postoperative TR were evaluated. De Vega annuloplasty seemed to bring better late result than Kay annuloplasty[p<0.05]. In four patients with late severe TR,previously replaced tissue valve degeneration[2], pulmonary hypertension[1] and rheumatic TR[1] were the possible causes. This experience suggests that De Vega annuloplasty can be a reliable method in the majority of patients with moderate-to-severe functional TR.