• Title/Summary/Keyword: FEO

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Polymorphism of the Helicobacter pylori feoB Gene and Clinical Correlation with Iron-deficiency Anemia in Korea (Helicobacter pylori feoB 유전자의 다형성과 철 결핍성 빈혈과의 관계)

  • Min, Kee-Woon;Jeon, Byung-Ha;Oh, Yoo-Joung;Choe, Yon-Ho
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.6 no.2
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    • pp.112-119
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    • 2003
  • Purpose: Helicobacter pylori infection is thought to be correlated with iron-deficiency anemia (IDA) at puberty. The H. pylori feoB gene, a high-affinity ferrous iron transporter, plays a central role in iron acquisition. This study aims to analyze the H. pylori feoB status according to the presence of antral gastritis with or without IDA. Methods: Fourteen H. pylori-positive patients aged from 10~18 years were categorized into subgroups based on the presence or absence of IDA. Eight patients had IDA, and the other six showed normal hematological findings. Genomic DNA was isolated from cultured H. pylori. Five sets of primers were used for PCR amplification of the feoB gene. The feoB region, 1.93 kb, was generated by linking of the PCR products and sequenced. The feoB gene sequences of H. pylori J99 and 26695 were used to compare with the clinical strains. Sequence comparisons of the feoB regions between the IDA (+) and (-) groups were performed. Results: Sequence analysis of the complete coding region of the feoB revealed 16 sites of polymorphism. Among these, 3 polymorphisms-Glu/Thr254Ala, Ile263Val, and Lys511Gln - were indigenous to Korean strains. Although statistically significant differences appear in 4 sites between IDA (+) and (-), the number of specimens are too low to assess the real differences. Conclusion: The 4 polymorphisms in the feoB gene seem to be related with IDA, but it is unclear yet because of small number of study strains. Further studies are required to prove the correlation of IDA and H. pylori infection.

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Olfactory Stimulation by Fennel (Foeniculum vulgare Mill.) Essential Oil Improves Lipid Metabolism and Metabolic Disorders in High Fat-Induced Obese Rats

  • Seong Jun Hong;Sojeong Yoon;Seong Min Jo;Hyangyeon Jeong;Moon Yeon Youn;Young Jun Kim;Jae Kyeom Kim;Eui-Cheol Shin
    • Journal of Web Engineering
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    • v.14 no.4
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    • pp.741-755
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    • 2022
  • In this study, odor components were analyzed using gas chromatography/mass spectrometry (GC/MS) and solid-phase microextraction (SPME), and odor-active compounds (OACs) were identified using GC-olfactometry (GC-O). Among the volatile compounds identified through GC-O, p-anisaldehyde, limonene, estragole, anethole, and trans-anethole elicit the fennel odor. In particular, trans-anethole showed the highest odor intensity and content. Changes in body weight during the experimental period showed decreasing values of fennel essential oil (FEO)-inhaled groups, with both body fat and visceral fat showing decreased levels. An improvement in the body's lipid metabolism was observed, as indicated by the increased levels of cholesterol and triglycerides and decreased levels of insulin in the FEO-inhaled groups compared to group H. Furthermore, the reduction in systolic blood pressure and pulse through the inhalation of FEO was confirmed. Our results indicated that FEO inhalation affected certain lipid metabolisms and cardiovascular health, which are obesity-related dysfunction indicators. Accordingly, this study can provide basic research data for further research as to protective applications of FEO, as well as their volatile profiles.

Gallium(III) Nitrate Inhibits Pathogenic Vibrio splendidus Vs by Interfering with the Iron Uptake Pathway

  • Song, Tongxiang;Zhao, Xuelin;Shao, Yina;Guo, Ming;Li, Chenghua;Zhang, Weiwei
    • Journal of Microbiology and Biotechnology
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    • v.29 no.6
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    • pp.973-983
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    • 2019
  • It is well known that iron is critical for bacterial growth and pathogenic virulence. Due to chemical similarity, $Ga^{3+}$ competes with $Fe^{3+}$ for binding to compounds that usually bind $Fe^{3+}$, thereby interfering with various essential biological reactions. In our present study, gallium(III) nitrate [$Ga(NO_3)_3$] could repress the growth of V. splendidus Vs without complete inhibition. In the presence of $Ga(NO_3)_3$, the secretion of homogentisic acid-melanin (HGA-melanin) in V. splendidus Vs cells could be increased by 4.8-fold, compared to that in the absence of $Ga(NO_3)_3$. HGA-melanin possessed the ability to reduce $Fe^{3+}$ to $Fe^{2+}$. In addition, HGA-melanin increased the mRNA levels of feoA and feoB, genes coding Fe2+ transport system proteins to 1.86- and 6.1-fold, respectively, and promoted bacterial growth to 139.2%. Similarly, the mRNA expression of feoA and feoB was upregulated 4.11-fold and 2.71-fold in the presence of $640{\mu}M$ $Ga(NO_3)_3$, respectively. In conclusion, our study suggested that although $Ga(NO_3)_3$ could interfere with the growth of V. splendidus Vs, it could also stimulate both the production of $Fe^{3+}$-reducing HGA-melanin and the expression of feoA and feoB, which facilitate $Fe^{2+}$ transport in V. splendidus Vs.

Study on Atmospheric Corrosion for Two Different Marine Environments in India

  • Saha, Jayanta Kumar
    • Corrosion Science and Technology
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    • v.6 no.3
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    • pp.120-127
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    • 2007
  • In any developing nation major investment goes for infrastructure and it is not exception in India. Good numbers of buildings, bridges, shopping malls, car parks etc. are coming up with steel for sustainable development. Thus protecting the structures from corrosion are the challenges faced by professionals for all types of steel structures. About 3% of GDP is accounted for loss due to corrosion. To combat this up to date corrosion map is called for as the country has wide variation of climatic zones with vastcoastline. Logically organic paint system can be prescribed based on the corrosion rate on bare steel with respect to environment. Present paper will emphasis on the study conducted on two types of structural steel coated with organic paint located in twomarine environment having been exposed for three years, Test coupons made from steels both bare and coated are deployed at two field stations having marine (Digha) and industrial marine (Channai) environments. Various tests like AC impedance DC corrosion, polarisation, salt spray test, $SO_2$ chamber and Raman spectroscopy were carried out both in laboratory on fresh as well as coupons collected from exposure sites. Rust formed on the bare and scribed coated coupons are investigated. It is found that normal marine environment at Digha exhibits higher corrosion rate than polluted marine environment in Channai. Rust analysis indicates formation of ${\propto}$-FeoOH protects or reduces corrosion rate at Channai and formation of non-protective ${\gamma}$-FeoOH increases corrosion rate at Digha. The slower corrosion rate in Channai than at Digha is attributed due to availability of $SO_2$, in the environment, which converts non‐protective rust ${\gamma}$-FeoOH to protective rust ${\propto}$-FeoOH. While comparing the damage on the coated panels it is found that low alloy structural steel provides less damage than plain carbon steel. From the experimentations a suitable paint system specification is drawn for identical environments for low medium and high durability.

Limit State Analysis of Earthern Slope Using a Continuum Mechanics Approach (연속체 역학을 이용한 사면의 한계상태 해석)

  • 서영교
    • Journal of the Korean Geotechnical Society
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    • v.16 no.5
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    • pp.141-148
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    • 2000
  • 사면 안정 해석은 주로 파괴 활동면의 전단 강도와 발휘되는 전단 강도의 최대비로서 표현되는 파괴활동의 추정을 위해 기존의 고전적인 방법을 사용하거나 이와 유사한 방법등이 사용되어 왔다. 이러한 방법들은 토질에 있어서의 상호 작용력과 그에 따른 전당력 및 사면 활동면의 반복되는 추정등의 가정으로 불확실성을 내포하고 있다. 본 연구에서는 토질전체를 연속체로 규정하고 비선형 유한요소법을 이용한 토질의 실제 응력과 강도를 정확하게 계산하였다. 사면 안정은 점차적 인증력의 증가로서 사면의 붕괴 활동면이 나타나FEo 까지로 해석되었다. 제시된 방법의 세부적인 사항은 예제를 통하여 설명되어 있다.

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Isogeny 기반 암호의 최신 연구 동향

  • Kim, Suhri
    • Review of KIISC
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    • v.32 no.1
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    • pp.19-29
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    • 2022
  • 2011 Jao와 De Feo에 의해 제안된 SIDH가 기존 타원곡선 사이의 isogeny를 이용한 암호보다 효율적인 성능을 제공하고, 그 후 2016년 Costello 등의 효율적인 연산 방법으로 SIDH 속도가 3배 이상 향상되면서, 타원곡선 사이의 isogeny를 이용한 암호가 양자 컴퓨팅 환경에서 RSA와 ECC를 대체할 암호로 주목을 받기 시작했다. 특히 isogeny 기반 암호는 다른 PQC 암호에 비해 작은 키 사이즈를 제공한다는 장점으로 현재까지 활발히 연구가 진행되고 있으며, SIDH를 기반으로 둔 SIKE는 NIST PQC 표준화 공모전 Round 3의 대체 후보이다. 다른 PQC 암호에 비해 속도가 느리다는 점이 isogeny 기반 암호의 단점인 만큼, isogeny 기반 암호는 처음 제안된 후 10년 동안 최적화를 중심으로 큰 발전을 이뤄왔다. 본 논문에서는 isogeny 기반 암호의 최신 연구 동향을 소개한다.

Preliminary Experiments for the Remediation of Trichloroethene-Contaminated Groundwater Using Direct-Current and Zero-Valent Iron (0가 철과 직류전원을 이용한 TCE 오염 지하수의 정화기법 예비조사)

  • Moon, Ji-Won;Moon, Hi-Soo;Roh, Yul;Lee, Suk-Young;Song, Yun-Goo
    • Economic and Environmental Geology
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    • v.34 no.3
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    • pp.307-313
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    • 2001
  • Reactive medium including zero-valent metals such as zero-valent iron ($Fe^0$) degrades chlorinated solvents as a contaminant plume flows through the treatment medium. Although the Feo based reactive barrier has been demonstnlted to be a cost effective for trichloroethenc (TCE)-contaminaled plume remediation, current approach is limited by low process eftlciency and uncertain, effective life of the medium. The objective of this study is to develop an enhanced treatment method of TeE-contaminated groundwater using Feo and direct current. The bench-scale test using flow-through $Fe^0$ reactor column confirmed that the application of direct current with $Fe^0$ is highly effective in enhancing the rate of TeE dechlorination. The dechlorination mechanism appears to be reductive, with the electrons supplied by the iron oxidation and external power supply serving as the additional source of electrons.

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An Evaluation on the Operating of Fisheries Extension Services (어촌지도사업의 평가)

  • 최정윤
    • The Journal of Fisheries Business Administration
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    • v.17 no.2
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    • pp.65-106
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    • 1986
  • 1, The Purpose of Study This is a study on the Evaluation of the operating of Fisheries Extension Services of Korea, for performing the activities such as guiding fisheries technique as well as offering industrial information to the fishermen in fishing village. By doing so, the Fisheries Extension Sevices(FES) can materialize the continued growth of fisheries, the social and economic development of fishing village, and the increase in income by enhancing the knowledge level of Fishermen, etc. In performing fisheries policy, this activity plays a great role on the research and development activity, and it has become practical since 1976 in Korea. In order to meet immediately with the problem of fisheries technical innovation and rapid environmental changes surrounding the fisheries, the fishermen should not only enhance their scientific and comprehensive capacity in fisheries technique but abtain various effective information. Generally, as most of all the fishemen are poor in the managerial structure and scattered in fishing villages, they have little opportunity in the contact of information. As a result, it is nessessary for the FES to perform the fishing business by the extension service officials who has received special training and acquired fisheries know-how in these fields. And yet, FES is under the unfullfilled circumstance in such factors as manpower, technical know-how, equipment, and the service system etc., which is required in promoting the social, economic development of fishing village and in resolving the high technique demand of fisherman. This study on the fisheries extension services have been studied from those backgrounds. 2. Research Method The data of collecting methods which were necessary in carrying out this study was adopted by the questionaire research on the present extension service activity, through the subject of the extension services (driving agency of the work and the officials), the object(fishemen) and the 3rd observers to the extension services (the authorities concerned). The research sample was taken by the sampling extraction of total 1, 774 men from the above 3 groups. And the research was carried out from August, 1986 to October, 1986, supported from the Fisheries Extension Office (FEO) located in field during the research process. In this study, the levels of the extension operating were determined and estimated in accordance with the extension service method, morale of extension service officials and the extension service system, etc. through the collected data of the research questionaire paper. And based on this result, the essential conditions of the extension services were grasped, and also we tried to present the various activity plan necessary to promote the operating of the extension services. The questionaire research data was calculated by the computer center of National Fisheries University of Pusan, and the total result was again tried on the one demension analysis along with two dimension analysis to search out the relativity between the questionaire, and the statistical test was done $\chi$$^2$test in significance level of l~5%. 3. Contents of Study This study consists of 7 chapters and the contents are as follows : Chapter I : The object and method of the study Chapter II : The assessment and analysis of the extension services Chapter III : The contents and method of the extension services Chapter IV : Analysis of the essential conditions for the extension services Chapter V : The evaluation of activities of extension services Chapter Ⅵ : Conclusion.4. Results and RecommendationTherefore, the results of this study estimated by logical process and analysis are as follows : 1) Most of Korean fishing villages and coastal fishermen have shown much concerns about fisheries technique and social changes, thus many of them were confronted with new problems on how to adapt and to meet changes. 2) Majority of fishermen estimated FEO as an organization of specific technologies with all the thing concerning the fisheries technique in general. Therefore the fishermen wanted to utilize the FEO as an adaptable method for the modern fisheries techniques as well as the environmental changes. 3) In contrast with the fast changes of the fisheries technique, the complexity and variety of technical system and the broadness of fishing village and fishermen, it was revealed that the necessary factors such as the facilities, manpower, budget, and the level of applying techniques of the FEO located in field were highly insufficient. Accordingly, the guiding efficiency was low and the extension services did not provide full solution to the various request from fishermen. 4) It is possible to classify the activation factor for the extension service into two large dimension ; personal dimension relevant to guidance officials and work dimension relevant to the organization. And it was found that the activation level of the work dimension was far lower than the personal dimension between them. So, the activation should be done first in the dimesion to promote the activation of the extension services. 5) The extension services officials are now demoralized in general, thus it is necessary to take reality into consideration : the expense of activity, the adequate endowment of activity scope and the reasonable operation of the position class, etc to enhance its morale. However, in order to do the FES activation, first of all, the systems should be established which is lain unsettled stage until now. And there must be change in the understanding of government i.e. the fisheries extension services are the essential policy subject to build up the base of fisheries growth and modernize the fisheries management. And it should be driven positively with the recognition of the "lasting project".g project".uot;.

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Volatiles of Chrysanthemum zawadskii var. latilobum K.

  • Chang, Kyung-Mi;Kim, Gun-Hee
    • Preventive Nutrition and Food Science
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    • v.17 no.3
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    • pp.234-238
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    • 2012
  • The volatile aroma constituents of Chrysanthemum zawadskii var. latilobum K. were separated by hydro distillation extraction (HDE) method using a Clevenger-type apparatus, and analyzed by gas chromatography-mass spectrometry (GC/MS). The yield of C. zawadskii var. latilobum K. flower essential oil (FEO) was 0.12% (w/w) and the color was light green. Fifty-five volatile chemical components, which make up 88.38% of the total aroma composition, were tentatively characterized. C. zawadskii var. latilobum K. FEOs contained 27 hydrocarbons, 12 alcohols, 7 ketones, 4 esters, 1 aldehyde, 1 amine, and 3 miscellaneous components. The major functional groups were terpene alcohol and ketone. Borneol (12.96), (${\pm}$)-7-epi-amiteol (12.60), and camphor (10.54%) were the predominant volatiles. These compounds can be used in food and pharmaceutical industries due to their active bio-functional properties.

Omega-3 and -9 Fatty Acid Combination Effects on Broiler Chicks to Produce Chicks with High in Omega-3 Polyunsaturated Fatty Acid (오메가-3와 -9 지방산의 혼합 급이가 계육내 오메가-3 계열 다가불포화지방산의 조성에 미치는 영향)

  • Shin, Dae-Keun;Choi, Seung-Ho;Cho, Young-Moo;Park, Jae-Hong
    • Korean Journal of Poultry Science
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    • v.39 no.1
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    • pp.1-8
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    • 2012
  • To evaluate the effects of n-3 and n-9 fatty acid combination on broiler chicks, diets containing the combinations of five different fat sources including flaxseed oil, fish oil, EPA, DHA and olive oil were provided, and all chicks were processed at 4 weeks of growth. Liver, breast and thigh samples were collected and fatty acid composition and/or CIE $L^*$, $a^*$ and $b^*$ measurement were measured. Also, live chick and liver weights were weighed and the ratio was provided as an evidence of fat accumulation in liver. No significant difference was determined in both live and liver weight ratio and liver color. EPA was low in FHO as compared to livers from others. In contrast, DHA was significantly high in FHO. In broiler breasts derived from FDO, AA and n-3 fatty acid content was high, but only numerical differences of EPA and DHA were determined in breasts from FDO. The thighs from FHO showed high in EPA, DHA and n-3 fatty acid content but had low in AA and n-6 to n-3 ratio. Therefore, the results indicate that broiler chicken diets containing either FDO or FHO may be possible combination diets increasing n-3 polyunsaturated fatty acids in broiler chicks.