• 한국자기공명학회논문지
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• 제21권3호
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• pp.102-108
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• 2017

Escherichia coli responds to ever-changing external and internal stresses by rapidly adjusting its physiology for better survival. This adjustment occurs at all levels including metabolites as well as mRNAs and proteins. Although there has been many reports describing E. coli's adaptation to various stresses regarding transcriptomics or proteomics, only a few investigations have been reported regarding this adaptation viewed from metabolites' perspective. We applied four different types of stresses at four different doses as imposed by NaCl, sorbitol, ethanol, and pH to investigate the similarities or differences among the stresses, and which stress causes the largest perturbation of the metabolite composition. We profiled the metabolites under such external stresses by using two-dimensional NMR spectroscopy and identified 39 metabolites including amino acids, sugars, organic acids, and nucleic acids. According to our statistical analysis, the osmotic stress caused by sorbitol differentiated itself from others, while NaCl showed the largest dose dependent metabolic perturbations. We hope this work will form a foundation on which an approach to a successful protein production is systematically provided by a favorable metabolic environment by imposing proper external stresses.

• 콘크리트학회논문집
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• 제21권4호
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• pp.513-521
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• 2009

최근 들어 외부 강선을 이용한 프리스트레스트 콘크리트구조물의 건설이 증가하고 있다. 그러나 극한거동 해석시 단면 적합조건을 이용하는 내부 부착 강선과는 다르게 외적 비부착 강선은 부재의 전체거동에 의해서 응력 증 가량이 결정된다. 또한 편향부에서의 미끌림 효과와 강선의 편심 변화 효과 등이 발생하게 된다. 따라서 본 연구는 외 부 강선을 가지는 프리스트레스트 콘크리트(PSC) 보의 거동 특성을 평가하기 위하여 강선량, 긴장력 등을 변수로 하여 정적 휨실험을 수행하여 외부 강선 부재의 휨거동 특성을 얻었다. 실험 결과에 의하면 균열발생 이전의 외부 강선 PSC 부재는 부착 강선 PSC부재와 거동 차이가 크지 않음을 알 수 있었다. 그러나 균열이 발생한 이후의 거동에서는 철근의 항복하중, 극한하중, 강선 응력 등이 외부 강선 부재에서의 값이 부착 강선 부재에 비해서 작게 나타나고 있다. 하중-강 선 변형률 관계에서 보면, 외부 강선 부재들의 경우, 하중 증가에 따른 외부 강선 변형률의 증가량은 초기 긴장력의 크 기 순서와 거의 반대의 순서로 외부 강선의 변형률이 증가한 것으로 나타났으나, 다만 초기 긴장력이 크다할지라도 강 선의 유효응력이 작은 경우의 강선 변형률은 강선의 유효응력이 큰 부재들보다는 다소 작게 증가하고 있는 것으로 나 타났다. 외부 강선 부재의 콘크리트에 발생된 압축 변형률의 크기는 외부 강선의 유효응력 크기 순서와 일치하는 것으 로 나타나, 콘크리트의 압축변형률은 외부 강선의 유효응력에 비례함을 알 수 있다. 실험 결과와 기존의 설계식과 비교 해본 결과, ACI-318에 의한 결과는 긴장력 혹은 유효응력이 차이를 전혀 반영하지 못하고 있고 특히, 그 결과가 실험 결과보다 상당히 작게 나타나, 지나치게 보수적인 것으로 판단된다. 한편 AASHTO 1994는 ACI-318과는 다르게 강선량, 초 기 힘 및 유효응력 등의 변화에 적절하게 영향을 받고 있는 것으로 나타났지만 내부 비부착 강선의 실험 결과를 이용 하여 작성된 이유로 외부 강선 실험 결과보다 지나치게 큰 결과를 유발하고 있는 것으로 평가된다. 이러한 이유로 외 부 강선의 극한응력을 정확하게 예측할 수 있는 새로운 규정이 필요하다.

• 대한치과보철학회지
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• 제43권4호
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• pp.544-561
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• 2005

Purpose : This study was to assess the loading distributing characteristics of implant systems with internal connection or external connection under vertical and inclined loading using finite element analysis. Materials and methods : Two finite element models were designed according to type of internal connection or external connection The crown for mandibular first molar was made using cemented abutment. Each three-dimensional finite element model was created with the physical properties of the implant and surrounding bone This study simulated loads of 200N at the central fossa in a vertical direction (loading condition A), 200N at the centric cusp tip in a 15$^{\circ}$ inward inclined direction (loading condition B), or 200N at the centric cusp tip in a 30$^{\circ}$ outward inclined direction (loading condition C) respectively. Von Mises stresses were recorded and compared in the supporting bone, fixture, abutment and abutment screw. Results : 1. In comparison with the whole stress or the model 1 and model 2, the stress pattern was shown through th contact of the abutment and the implant fixture in the model 1, while the stress pattern was shown through the abutment screw mainly in the model 2. 2. Without regard to the loading condition, greater stress was taken at the cortical bone, and lower stress was taken at the cancellous bone. The stress taken at the cortical bone was greater at the model 1 than at the model 2, but the stress taken at the cortical bone was much less than the stress taken at the abutment, the implant fixture, and the abutment screw in case of both model 1 and model 2. 3. Without regard to the loading condition, the stress pattern of the abutment was greater at the model 1 than at the model 2. 4. In comparison with the stress distribution of model 1 and model 2, the maximum stress was taken at the abutment in the model 1. while the maximum stress was taken at the abutment screw in the model 2. 5. The magnitude of the maximum stress taken at the supporting bone, the implant fixture, the abutment, and the abutment screw was greater in the order of loading condition A, B and C. Conclusion : The stress distribution pattern of the internal connection system was mostly distributed widely to the lower part along the inner surface of the implant fixture contacting the abutment core through its contact portion because of the intimate contact of the abutment and the implant fixture and so the less stress was taken at the abutment screw, while the abutment screw can be the weakest portion clinically because the greater stress was taken at the abutment screw in case of the external connection system, and therefore the further clinical study about this problem is needed.

• 해양환경안전학회:학술대회논문집
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• 해양환경안전학회 2003년도 춘계학술발표회
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• pp.153-158
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• 2003

Design of general steel structure had applied and achieve elastic design concept mainly so far. Because elastic design supposes that whole structure complies with elasticity formula as that achieve via allowable stress of material is concept that calculate stress distribution of construction about action external load and estimate load of when the maximum stress reaches equally with allowable stress that is established beforehand by maximum safety load of the structure. But, absence that compose actuality structure by deal with external load increase small success surrender and structure hardness falls and tell structure in limit state finally on the whole as showing complicated conduct by interference between these breakdown at buckling by compression. Examined closely about conduct of place since initial buckling through carbon vocal cords transformation finite element analysis series (ANSYS) that place mending condition supposes case that is boundary condition in this investigation.

• Interaction and multiscale mechanics
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• 제1권4호
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• pp.437-448
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• 2008

This paper examined the stability of high-dense dislocation substructures (HDDSs) associated with martensite laths in High Cr steels supposed to be used for FBR, based on a series of dislocation dynamics (DD) simulations. The DD simulations considered interactions of dislocations with impurity atoms and precipitates which substantially stabilize the structure. For simulating the dissociation processes, a point defect model is developed and implemented into a discrete DD code. Wall structure composed of high dense dislocations with and without small precipitates were artificially constructed in a simulation cell, and the stability/instability conditions of the walls were systematically investigated in the light of experimentally observed coarsening behavior of the precipitates, i.e., stress dependency of the coarsening rate and the effect of external stress. The effect of stress-dependent coarsening of the precipitates together with application of external stress on the subsequent behavior of initially stabilized dislocation structures was examined.

• 아동학회지
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• 제18권1호
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• pp.39-52
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• 1997

This study focused on factors influencing Internal and external problem (depression and antisocial) behavior among late-elementary children. Subjects were 481 boys and girls enrolled in the fourth. fifth. and sixth grades of public school. The contribution of grade. sex. stress, self-esteem. and social support from parents, teachers, and friends as well as school performance were studied. The instruments were the Adolescent Perceived Events Scale, the Self-Esteem Scale, the Social Support Scale for Children, the Revised Korean Version of the Center for Epidemiologic Studies' Depression Scale and Antisocial Behavior Scale. Results indicated that sex, stress, self-esteem, and the support of parents, teachers and friends reduced the level of depression. Grade, sex, stress, self-esteem, and teachers' support were related to the level of antisocial behavior. The results were discussed in terms of the effects of stress, personal and social resources, and school achievement on depression and antisocial behavior.

• International Journal of Korean Welding Society
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• 제5권1호
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• pp.60-65
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• 2005

In the field of welding the mechanical behavior of a welded structure under consideration may be predicted via heat transfer and welding residual stress analysis. Usually such numerical analyses are limited to small regular mesh models or test specimens. Nevertheless, there is very few strength assessment of the whole structure that includes the effect of welded residual stress. The present work is based on the specialized finite element codes for the calculation of nonlinear heat transfer details and residual stress including the external load on the welded RHS (Rectangular Hollow Section) T-joint connections of the whole structure. First the thermal history of the combined fillet and butt-welded T-joint equal width cold-formed RHS are calculated using nonlinear finite element analysis (FEA) considering the quarter model of the joint. Then using this thermal history the residual stress around the joints has been evaluated. To validity the FEA result, the calculated residual stresses were compared with the available experimental results. The residual stress obtained from the quarter model is mapped to the full model and then to the whole structure model using FEM codes. The results from the FEM codes were exported to the commercial package for visualization and further analysis applying loads and boundary conditions on the whole structure. The residual stress redistribution along with the external applied load is examined computationally.

• 한국신뢰성학회지:신뢰성응용연구
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• 제13권2호
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• pp.141-151
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• 2013

The study of environmental stress cracking (ESC) by contact with plastic rulers and PVC erasers which was artificially added to the external stress was carried out in order to accelerate the chemicals crack. To analyze a blooming plasticizer that migrates from the inside of blended eraser to the surface of the eraser, the ESC experiments were carried out at room temperature and $50^{\circ}C$ conditions. The chemicals crack shape caused by the plasticizer and the brittle fracture shape resulted from the external stress were observed in consequence with the cross-sectional surface analysis of the ruler crack by the ESC. The bending strength of the plastic rulers were fractured prior to the yield point and it had low bending flexure stress. We presented that ESC of polymer materials was affected by the polarity of the chemicals and polymer, the exposure time to chemicals, the exposure temperature and the level of strain on the polymer.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1999년도 학회창립 10주년 기념 1999년도 가을 학술발표회 논문집
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• pp.681-684
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• 1999

The development of external prestressing methods has been one of the major trends in the concrete bridge constructions over the past decades. One of the promising methods to enhance the flexural strength of a externally prestressed girder is to place the tendons with large eccentricities. The test results in this study showed that the external prestressing of a composite girder increased the range of the elastic behavior, reduced deflections, increased ultimate strength, and added to the redundancy by providing the multiple stress paths. This study was conducted on the concrete bridges reinforced by the continuous girders and the external prestressing.

• 대한치과보철학회지
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• 제42권2호
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• pp.226-237
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• 2004

Purpose: Four finite element models were constructed in the mandible having a single implant fixture connected to the first premolar-shaped superstructure, in order to evaluate how the shape of the fixture and the implant-abutment connection would influence the stress level of the supporting tissues fixtures, and prosthethic components. Material and methods : The superstructures were constructed using UCLA type abutment, ADA type III gold alloy was used to fabricate a crown and then connected to the fixture with an abutment screw. The models BRA, END , FRI, ITI were constructed from the mandible implanted with Branemark, Endopore, Frialit-2, I.T.I. systems respectively. In each model, 150 N of vertical load was placed on the central pit of an occlusal plane and 150 N of $40^{\circ}$ oblique load was placed on the buccal cusp. The displacement and stress distribution in the supporting tissues and the other components were analysed using a 2-dimensional finite element analysis . The maximum stress in each reference area was compared. Results : 1. Under $40^{\circ}$ oblique loading, the maximum stress was larger in the implant, superstructure and supporting tissue, compared to the stress pattern under vertical loading. 2. In the implant, prosthesis and supporting tissue, the maximum stress was smaller with the internal connection type (FRI) and the morse taper type (ITI) when compared to that of the external connection type (BRA & END). 3. In the superstructure and implant/abutment interface, the maximum stress was smaller with the internal connection type (FRI) and the morse taper type (ITI) when compared to that of the external connection type (BRA & END). 4. In the implant fixture, the maximum stress was smaller with the internal connection type (FRI) and the morse taper type (ITI) when compared to that of the external connection type (BRA & END). 5 The stress was more evenly distributed in the bone/implant interface through the FRI of trapezoidal step design. Especially Under $40^{\circ}$ oblique loading, The maximum stress was smallest in the bone/implant interface. 6. In the implant and superstructure and supporting tissue, the maximum stress occured at the crown loading point through the ITI. Conclusion: The stress distribution of the supporting tissue was affected by shape of a fixture and implant-abutment connection. The magnitude of maximum stress was reduced with the internal connection type (FRI) and the morse taper type (ITI) in the implant, prosthesis and supporting tissue. Trapezoidal step design of FRI showed evenly distributed the stress at the bone/implant interface.