• Title/Summary/Keyword: Excess risk

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First Clinical Experience about RapidArc Treatment with Prostate Cancer in Ajou University Hospital (아주대학교병원에서의 전립선암에 대한 래피드아크 치료)

  • Park, Hae-Jin;Kim, Mi-Hwa;Chun, Mi-Son;Oh, Young-Teak;Suh, Tae-Suk
    • Progress in Medical Physics
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    • v.21 no.2
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    • pp.183-191
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    • 2010
  • In this study, the patient with localized prostate cancer who had previously been treated at Ajou University Hospital was randomly selected since March, 2009. we performed IMRT and 2RA plans and the same dose objectives were used for CTVs, PTVs, rectum, bladder, and femoral head of the respective plans. Arc optimizations and dose calculations were performed using Eclipse versions 8.6. In this paper, we evaluated the performance of IMRT and RA plans to investigate the clinical effect of RA for prostate cancer case. In our comparison of treatment techniques, RA was found to be superior to IMRT being better dose conformity of target volume. As for the rectum and bladder, RA was better than IMRT at decreasing the volume irradiated. RA has the ability to avoid critical organs selectively through applied same dose constraints while maximally treating the target dose. Therefore, this result suggests that there should be less rectal toxicity with RA compared with IMRT, with no compromise in tumor margin. These findings, which show more favorable rectal, bladder, and femoral head DVHs with RA, imply that should not result in excess risk of toxicity when this technique is used. Many experiences with RA have shown not only dosimetric advantage, but also improved clinical toxicity when comparing with IMRT. The main drawbacks of RA are the more complex and time-consuming treatment planning process and the need for more exact physics quality assurance (QA).

Test methodology of acceleration life test on feeder cable assembly (Feeder Cable Assembly의 가속수명시험법 개발)

  • Han, Hyun Kak
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.8
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    • pp.62-68
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    • 2016
  • The feeder cable assembly is an automotive part used for telecommunication. If it malfunctions, the control and safety of the automobile can be put at risk. ALT (Accelerated Life Testing) is a testing process for products in which they are subjected to conditions (stress, strain, temperatures, etc.) in excess of their normal service parameters in an attempt to uncover faults and potential modes of failure in a short amount of time. Failure is caused by defects in the design, process, quality, or application of the part, and these defects are the underlying causes of failure or which initiate a process leading to failure. Thermal shock occurs when a thermal gradient causes different parts of an object to expand by different amounts. Thermal shock testing is performed to determine the ability of parts and components to withstand sudden changes in temperature. In this research, the main causes of failure of the feeder cable assembly were snapping, shorting and electro-pressure resistance failure. Using the Coffin-Manson model for ALT, the normal conditions were from Tmax = $80^{\circ}C$ to Tmin = $-40^{\circ}C$, the accelerated testing conditions were from Tmax = $120^{\circ}C$ to Tmin = $-60^{\circ}C$, the AF (Acceleration Factor) was 2.25 and the testing time was reduced from 1,000 cycles to 444 cycles. Using the Bxlife test, the number of samples was 5, the required life was B0.04%.10years, in the acceleration condition, 747 cycles were obtained. After the thermal shock test under different conditions, the feeder cable assembly was examined by a network analyzer and compared with the Weibull distribution modulus parameter. The results obtained showed good results in acceleration life test mode. For the same reliability rate, the testing time was decreased by a quarter using ALT.

Prognosis in the Patients with Prolonged Extracorporeal Membrane Oxygenation

  • Kim, Tae-Hun;Lim, Cheong;Park, Il;Kim, Dong-Jin;Jung, Yo-Chun;Park, Kay-Hyun
    • Journal of Chest Surgery
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    • v.45 no.4
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    • pp.236-241
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    • 2012
  • Background: Prolonged usage of extracorporeal membrane oxygenation (ECMO) may induce multi-organ failure. This study is aimed to evaluate prognostic factors in the patients with ECMO. Also, the prognosis of ECMO with Kidney Injury Network Scoring system is studied. Materials and Methods: From May 2005 to July 2011, 172 cases of ECMO were performed. The cases of perioperative use of ECMO were excluded. Renal failure patient and younger than 15 years old one were also excluded. As a result, 26 cases were enrolled in this study. Male patients were 15 (57.7%), and mean age was $56.57{\pm}17.03$ years old. Demographic data, ECMO parameters, weaning from ECMO, and application of continuous renal replacement therapy are collected and Acute Kidney Injury Network (AKIN) scores were evaluated just before ECMO and day 1, day 2 during application of ECMO. Results: Venoarterial ECMO was applied in 22 cases (84.6%). The reasons for applications of ECMO were cardiac origin in 21 (80.8%), acute respiratory distress syndrome in 4, and septic shock in 1 case. Successful weaning from ECMO was achieved in 15 cases (57.7%), and survival discharge rate was 9 cases (34.6%). Mean duration of application of ECMO was $111.39{\pm}54.06$ hours. In univariate analysis, myocarditis was independent risk factors on weaning failure. Using the receiver operating characteristic curve, level of hemoglobin on 24 hours after ECMO, and base excess on 48 hours after ECMO were showed more than 0.7. AKIN score was not matched the prognosis of the patients with ECMO. Conclusion: In our study, the prognosis of the patients with myocarditis was poor. Hemoglobin level at first 24 hours, and degree of acidosis at 48 hours were useful methods in relating with prognosis of ECMO. AKIN scoring system was not related with the prognosis of the patients. Further study for prognosis and organ injury during application ECMO may be needed.

Health Status and Nutrient Intakes of 5th Grade Elementary Students in Seoul and Gyeonggi ProvinceHealth Status and Nutrient Intakes of 5th Grade Elementary Students in Seoul and Gyeonggi Province (서울 및 경기 일부지역 초등학교 5학년의 건강상태 및 영양섭취실태)

  • Kim, Ok-Hyun;Park, Hyun-Ah;Cho, Young-Gyu;Kim, Kyoung-Woo;Hur, Yang-Im;Song, Ji-Hyun;Kang, Jae-Heon
    • Korean Journal of Community Nutrition
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    • v.15 no.6
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    • pp.717-726
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    • 2010
  • This study was conducted to investigate health status and nutrient intakes among 5th grade elementary students at Korea Centers for Disease Control and Prevention 2010. This study was cross-sectional study on 1,384 children (687 boys, 697 girls) from nine elementary schools located in Seoul and Gyeonggi province. The average height, weight and BMI were 145 cm, 40.6 kg $19.2\;kg/m^2$ for boys and 145.4 cm, 38.2 kg, $18.0\;kg/m^2$ for girls. The prevalence of overweight and obesity were 11.3%, 5.2%, respectively. Serum AST, ALT, glucose, HDL-Cholesterol and RBC levels were significantly higher, while TG levels was significantly lower for boys than for girls. The average energy intake was 1772.4 kcal, which was 98.7% of Estimated Energy Requirement (EER). The boys consumed more energy intake (1800.4 kcal) than the girls (1744.7 kcal). Also, they took insufficient calcium and folate (69.1% and 83.3% of Recommended Intake (RI)) and excess sodium (297.6% of Adequate Intake (AI)) and 85.1% of the subjects had breakfast everyday. In general, the proportion of the children who consumed fruits and vegetables at least once or more a day was low. There was a higher proportion of children in boys who had ramyun and milk with sufficient physical activity than those in girls. As a result of this study, we can find risk factors on obesity and metabolic disorders, and the results can be used for an evidence of nutrition education program and the intervention program.

A Survey on Harmful Materials of Commercial Medical Herb in Gwangju Area (광주지역 유통 한약재의 유해물질 잔류실태조사)

  • Lee, Hyang-Hee;Seo, Jung-Mi;Oh, Mu-Sul;Gang, In-Sook;Park, Jong-Jin;Seo, Kye-Won;Ha, Dong-Ryong;Kim, Eun-Sun
    • Journal of Food Hygiene and Safety
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    • v.25 no.2
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    • pp.83-90
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    • 2010
  • This study was conducted to investigate the residue amount of harmful materials on the 153 commercial medical herbs in Gwangju area. It was performed using the GC-ECD, GC-NPD, GC-MSD and the LC-UVD, LC-FLD, LC-MSD to analyze 200 pesticides. The heavy metals were determined using a Mercury analyzer and AAS. The sulfur dioxides were analyzed by modified Monnier-Williams method. The residual pesticides were detected in 7 samples, and were over MRLs (Maximum Risk Levels) in 2 samples (1.3%). The mean values of heavy metal contents (mg/kg) were Pb, 0.570; Cd, 0.081; As, 0.082; Hg, 0.0093. The measured values of Pb, As, Hg showed within MRLs. The excess samples of MRLs were 3 samples (changchul 2, cheongung 1) on Cd. The sulfur dioxides were over MRLs in 7 samples (4.6%), hwanggi and gugija. These results will be used to establish on the regulation of commercial medical herbs in Gwangju area.

Usefulness and Limitations of Extreme Value Theory VAR model : The Korean Stock Market (극한치이론을 이용한 VAR 추정치의 유용성과 한계 - 우리나라 주식시장을 중심으로 -)

  • Kim, Kyu-Hyong;Lee, Joon-Haeng
    • The Korean Journal of Financial Management
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    • v.22 no.1
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    • pp.119-146
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    • 2005
  • This study applies extreme value theory to get extreme value-VAR for Korean Stock market and showed the usefulness of the approach. Block maxima model and POT model were used as extreme value models and tested which model was more appropriate through back testing. It was shown that the block maxima model was unstable as the variation of the estimate was very large depending on the confidence level and the magnitude of the estimates depended largely on the block size. This shows that block maxima model was not appropriate for Korean Stock market. On the other hand POT model was relatively stable even though extreme value VAR depended on the selection of the critical value. Back test also showed VAR showed a better result than delta VAR above 97.5% confidence level. POT model performs better the higher the confidence level, which suggests that POT model is useful as a risk management tool especially for VAR estimates with a confidence level higher than 99%. This study picks up the right tail and left tail of the return distribution and estimates the EVT-VAR for each, which reflects the asymmetry of the return distribution of the Korean Stock market.

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A Study on the Long-Run Equilibrium Between KOSPI 200 Index Spot Market and Futures Market (분수공적분을 이용한 KOSPI200지수의 현.선물 장기균형관계검정)

  • Kim, Tae-Hyuk;Lim, Soon-Young;Park, Kap-Je
    • The Korean Journal of Financial Management
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    • v.25 no.3
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    • pp.111-130
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    • 2008
  • This paper compares long term equilibrium relation of KOSPI 200 which is underling stock and its futures by using general method fractional cointegration instead of existing integer cointegration. Existence of integer cointegration between two price time series gives much wider information about long term equilibrium relation. These details grasp long term equilibrium relation of two price time series as well as reverting velocity to equilibrium by observing difference coefficient of error term when it renounces from equilibrium relation. The result of this study reveals existence of long term equilibrium relation between KOSPI200 and futures which follow fractional cointegration. Difference coefficient, d, of 'two price time series error term' satisfies 0 < d < 1/2 beside bandwidth parameter, m(173). It means two price time series follow stationary long memory process. This also means impulse effects to balance price of two price time series decrease gently within hyperbolic rate decay. It indicates reverting speed of error term is very low when it bolts from equilibrium. It implies to market maker, who is willing to make excess return with arbitrage trading and hedging risk using underling stock, how invest strategy should be changed. It also insinuates that information transition between KOSPI 200 Index market and futures market does not working efficiently.

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Treatment of Obese Women with Low Calorie Diet, Aerobic Exercise and Behavior Modificaiton (저열량균형식, 운동 및 행동수정에 의한 비만여성의 치료에 관한 연구)

  • 장경자
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.24 no.4
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    • pp.510-516
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    • 1995
  • A multidisciplinary weight control program was conducted for obese women. The major components of the program included low calorie diet therapy, exercise, behavior modification and nutritional education and counseling. Sixteen healthy volunteers in excess of body fat, above 30%, were enrolled in the group support program. But 5 person were dropped out in the 2nd week of treatment. During the 1st week of group orientation, individual cause of obesity was assessed through a computer program including survey of dietary intake, activity, eating habits and life styles. During the 5 weeks of treatment, 4.8kg of average weight loss was accomplished using a following program ; low calorie diet(1200kcal/day with all essential nutrients), low impact aerobic exercise(50~60% of $VO_{2max}$, 1 hour/day in a group, 3~5 days/week), behavior modification of individual life styles and eating habits causing obesity and nutritional education concerning nutrition, role of exercise such as brisk walking, importance of slow eating in regular meal pattern and internal motivation for weight reduction, health risk of obesity and rapid weight loss, weight recycling and yo-yo syndrome, etc. Nutritional conseling was conducted 3 times per week with checking self-records of foods, activity, emotional state and tiredness. Before and immediately after 5 weeks of treatment, blood pressure, fasting blood glucose, cholesterol and triglyceride were measured and comparied with paired t-test. After 5 weeks of treatment, body weight, body mass index, body fat and circumferences of waist, upper arm and hip were significantly decreased. Also LDL-cholesterol was significantly decreased after obesity treatment.

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A Study On The Water Quality in Rural Area in Chuncheon-si (춘천시 일부 농촌 지역의 음용수 수질에 관한 조사연구)

  • Park, Sujung;Kim, Moon Kyung;Ki, Young Sun;Oh, So Rin;Shin, Mi-yeon;Oh, Ji Yoon;Byeon, Jae Cheol;Lee, Seong Min;Jung, Eun Hee;Kim, Eun Mi;Zoh, Kyung-Duk;Choi, Kyungho
    • Journal of Korean Society on Water Environment
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    • v.22 no.3
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    • pp.431-436
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    • 2006
  • This study was conducted in the summer of 2005 in Shindong-myeon, Chuncheon-si, Gangwon-do to assess the quality of drinking water and to evaluate their potential pollutants. Ninety four water samples were collected from three classes of water supplies such as simple piped water, supplied own water and others (Supplied local water). Most residents used simple piped water (72.63%). 31.25% residents thought the water quality was bad and landfill was the main source of pollution that affected water quality. To correspond this perception, water quality was measured according to Drinking Water Quality Standard. The general bacteria, coliforms, and $NO_3-N$ exceeded the standard but the water qualities in these four areas were suitable for Drinking Water Quality Standard. The simple piped water showed low mean concentration of excess rate compared to supplied own piped water except general bacteria. Hardness, pH, and $NO_3-N$ showed significantly higher effects on drinking water quality. To evaluate the effect of effluent from landfill, water quality was measured according to distance and altitude. However, there was no effect of landfill effluent. To find out the effect of rainfall, we compared water quality of the year 2003 with that of 2005. The result showed significant differences in hardness and $NO_3-N$ concentration. This study confirmed that $NO_3-N$, coliforms, and general bacteria are main pollutant of water supply in rural community. Therefore, it is necessary to regularly maintain simple piped water supply, supplement sewer facilities, and educate residents about public health risk associated with drinking water in rural area.

Study of N-Port Electric Vehicle Charging Systems Using OPC-UA (OPC UA를 이용한 N-Port EV 충전 시스템 연구)

  • Lee, Seong Joon
    • KIPS Transactions on Computer and Communication Systems
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    • v.6 no.8
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    • pp.343-352
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    • 2017
  • IEC62541, known as OPC-UA, is a standard communication protocol for Smart Grid (SG) and Smart Factory application platform. It was accepted as an IEC standard (IEC62541) in 2011 by IEC TC57, and is extending range of application as collaborating with other standrads. The government's policies to popularize EVs ("Workplace Charging Challenge"), the number of Electric vehicle which try to be charging in the factory is expected to increase. In this situation, indiscreet and uncontrolled EV charging can lead to some problems, such as excess of the peak demand capacity. Therefore, EVs, which is charging in SFs, must be monitoring and controlling to avoid and reduce peak demand. However, the standards for EVs charging differ from the standards for SFs. In other words, to increase the ease of use for drivers, and reduce risk for enterprise, we have needs of study to develop the protocols or to provide interoperability, for EVs charging in SFs. This paper deals with a EV charging management platform installing in a smart factory. And this platform can be easily integrated as part of SF management software. The main goal of this paper is to implement EV management system based on IEC61851 and IEC62541.