• 동의신경정신과학회지
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• 제31권4호
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• pp.301-314
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• 2020

Objectives: The purpose of this study was to provide clinical evidence to support the use of herbal medicine combined with western medicine for BPSD. Methods: Studies were identified by searching CNKI, Pubmed, EMBASE, Cochrane Library, SCIENCEON, RISS, KMbase, KISS, OASIS. Literature searches of Chinese, English, and Korean databases were performed. Two authors independently extracted the data and evaluated the quality of each study. Results: The literature search identified 203 articles. Of these, 7 were selected for the analysis. The risk of bias in most studies was unclear. The most frequently used diagnostic tools were the NINCDS-ADRDA and DSM-IV. The most commonly used results indicator was NPI. In 6 of the 7 papers, combination treatment (herbal & Western medicine) was statistically significantly more effective than single treatment (Western medicine alone) for BPSD. No significant adverse events were reported. Conclusions: Herbal medicine in combination with Western medicine is more effective for treating BPSD than Western medicine alone. However, the quality of the studies used in this study was uncertain and the sample size was too small. Based on the findings of this study, more high-quality clinical trials are needed to confirm the efficacy of combination treatment.

• Journal of Korea Trade
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• 제23권5호
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• pp.45-65
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• 2019

Purpose - As the well-known Structure-Conduct-Performance paradigm implies, risk structure of a corporation may affect its risk management activity and the activity may in turn determine its performance. Depending on its goal, Foreign Direct Investment (FDI) can shape its risk structure, risk management and its performance. Under this assumption, we investigate the relationship between the goals of FDI and risk management for the first time in academics. Design/methodology - This empirical research uses a survey of 279 current Korean enterprises' FDIs in China with the recently developed business risk quadrant model. Companies are classified into either a market- or an efficiency-seeking group, to identify how each group perceives and manages risks, and values the performance of risk management. Also, we apply integrated risk management method that multinational corporations have introduced in China, then verify the mediating effect between risk factors and performance. Findings - Our research shows the FDIs can expose themselves to differing risk structure although risk management activities simply represent the level of empowerment given to local management by headquarter due to limit of sample size despite diversity of risk and risk management tools. To sum, market seekers are found to have more strategic risk (revenue related risk) than efficiency seekers with financial risk (cost related risk). The market seekers can manage their risk by empowering their local organisation while the efficiency does the opposite ways. The risk management appears to be successful in general. Originality/value - Previous studies on small and medium enterprises' FDIs to China have concentrated on the analysis of entry determinants, withdrawal factors and individual risk management. Meanwhile, this research establishes enterprise-wide risk factors faced by the companies that advance into China, according to the method of the classification by ERM and verifies if they could synthetically improve performance through risk corresponding measures.

• 대한수의학회지
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• 제62권3호
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• pp.25.1-25.9
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• 2022

Canine cognitive dysfunction syndrome (CDS) is a neurodegenerative disease that causes cognitive and behavioral disorders and reduces the quality of life in dogs and their guardians. This study reviewed the complementary and alternative medicine (CAM) for CDS and compared the diagnosis and therapy of CAM between CDS in canines and dementia in humans. The evaluation tools for the diagnosis of CDS and dementia were similar in the neurological and neuropsychiatric examinations, daily life activity, cognitive tests, and neuroimaging, but the evaluation for dementia was further subdivided. In CAM, pattern identification is a diagnostic method for accurate, personalized treatment, such as herbal medicine. For herbal medicine treatment of cognitive impairment in canines and humans, a similar pattern identification classified as deficiency (Qi, blood, and Yin) and Excess (phlegm, Qi stagnation, and blood stasis) is being used. However, the veterinary clinical basis for verifying the efficacy and safety of CAM therapies for CDS is limited. Therefore, based on CAM evidence in dementia, it is necessary to establish CDS-targeted CAM diagnostic methods and therapeutic techniques considering the anatomical, physiological, and pathological characteristics of dogs.

• 한국환경보건학회지
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• 제49권5호
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• pp.275-288
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• 2023

Background: When basic local governments want to improve their air quality management policies, they need fundamental evidence, such as the effectiveness of current policies or scenario results. Objectives: The purpose of this study is to lay the groundwork for a process to calculate air pollutant reduction from basic local government air quality policies and provide numerical estimates of PM_2.5 concentrations following improved policies. Methods: We calculated the amount of air pollutant reduction that can be expected in the research region based on the Gyeonggi-do Air Environment Management Implementation Plan issued in 2021 and guidelines from the Korean Ministry of Environment. The PM_2.5 concentration variations were numerically simulated using the CMAQ (photochemical air quality model). Results: The research regions selected were Suwon, Ansan, Yongin, Pyeongtaek, and Hwaseong in consideration of population, air pollutant emissions, and geographical requirements. The expected reduction ratios in 2024 compared to 2018 are CO (3.0%), NO_x (7.9%), VOCs (0.7%), SO_x (0.1%), PM₁₀ (2.4%), PM_2.5 (6.1%), NH₃ (0.05%). The reduced PM_2.5 concentration ratio was highest in July and lowest in April. The expected concentration reduction of yearly mean PM_2.5 in the research region is 0.12 ㎍/m³ (0.6%). Conclusions: Gyeonggi-do is now able to quickly provide air pollutant emission reduction calculations by respective policy scenario and PM_2.5 simulation results, including for secondary aerosol particles. In order to provide more generalized results to basic local governments, it is necessary to conduct additional research by expanding the analysis tools and periods.

• Journal of Veterinary Science
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• 제25권2호
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• pp.28.1-28.11
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• 2024

Background: Porcine circovirus type 2 (PCV2) infection is ubiquitous around the world. Diagnosis of the porcine circovirus-associated disease requires clinic-pathological elements together with the quantification of viral loads. Furthermore, given pig farms in regions lacking access to sufficient laboratory equipment, developing diagnostic devices with high accuracy, accessibility, and affordability is a necessity. Objectives: This study aims to investigate two newly developed diagnostic tools that may satisfy these criteria. Methods: We collected 250 specimens, including 170 PCV2-positive and 80 PCV2-negative samples. The standard diagnosis and cycle threshold (Ct) values were determined by quantitative polymerase chain reaction (qPCR). Then, two point-of-care (POC) diagnostic platforms, convective polymerase chain reaction (cPCR, qualitative assay: positive or negative results are shown) and EZtargex (quantitative assay: Ct values are shown), were examined and analyzed. Results: The sensitivity and specificity of cPCR were 88.23% and 100%, respectively; the sensitivity and specificity of EZtargex were 87.65% and 100%, respectively. These assays also showed excellent concordance compared with the qPCR assay (κ = 0.828 for cPCR and κ = 0.820 for EZtargex). The statistical analysis showed a great diagnostic power of the EZtargex assay to discriminate between samples with different levels of positivity. Conclusions: The two point-of-care diagnostic platforms are accurate, rapid, convenient and require little training for PCV2 diagnosis. These POC platforms can discriminate viral loads to predict the clinical status of the animals. The current study provided evidence that these diagnostics were applicable with high sensitivity and specificity in the diagnosis of PCV2 infection in the field.

• 한방재활의학과학회지
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• 제34권3호
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• pp.43-51
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• 2024

Objectives The purpose of this study is to analyze trends of domestic research in Korean medicine treatment for rotator cuff tear. Methods Among the clinical papers published before March 2024, we used five databases for searching researches; Korean studies Information Service System, Oriental Medicine Advanced Searching Integrated System, Research Information Sharing Service, KMbase, ScienceON. Results 11 studies were finally selected. Acupuncture was used as a treatment in all 11 studies and pharmacopucture was used in 7 studies. Visual analogue scale and range of motion were frequently used as measurement tools. Most of the studies were case reports. Conclusions This study is a review about literatures on Korean medicine treatment for rotator cuff tear. In order to develop treatment and diagnosis of rotator cuff tear in the Korean medicine, more clinical studies with higher level of evidence should be conducted in the near future.

• 대한감각통합치료학회지
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• 제16권1호
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• pp.45-55
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• 2018

목적 : 본 연구는 성인을 대상으로 한 감각통합 중재를 체계적으로 분석함으로써 감각 통합 중재를 성인에게 적용할 수 있음을 알리고 그 근거를 제공하는 것을 목적으로 한다. 연구방법 : 전자 데이터베이스인 Pubmed, Scopus, SAGE Journal, Medline, RISS 데이터베이스를 사용하여 1980년부터 2017년까지의 논문을 검색하였다. 주요 검색어는"(sensory integration OR sensory processing OR sensory integrative OR sensory based OR sensory defensiveness) AND adult" 를 사용하였다. 최종적으로 8편의 논문을 본 연구의 분석대상으로 선정하였다. 선정된 논문은 Patient, Intervention, Comparison, Outcome(PICO) 형식을 사용하여 연구대상자, 중재 방법, 종속변인, 결과를 정리하였다. 결과 : 연구 대상자 유형에는 학습장애, 지적장애, 감각처리에 어려움이 있는 성인, 치매가 있었다. 종속변인에 따른 평가도구와 중재방법은 진단의 특성과 연구자의 연구 의도에 따라 다양하였으며, 중재결과는 대부분의 연구에서 효과적인 것으로 나타났다. 결론 : 본 연구를 통하여 감각통합중재가 성인에게 적용될 수 있음과 그 효과를 확인할 수 있었다. 이는 작업치료사에게 임상적 근거를 제공하고자 하였으며, 추후에는 본 연구결과를 바탕으로 성인을 대상으로 감각통합중재를 적용하는 방법에 대한 근거 마련을 위한 연구가 진행되어야 할 것이다.

• 해양환경안전학회지
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• 제13권4호
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• pp.55-63
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• 2007

집단감시 디지털 시스템(Group Digital Surveillance System for Fishery Safety and Security, GDSS-F2S)은 대단위 양식장에 침입하는 도적을 방어하기 위하여 물체 식별정보와 물체 추적정보를 제공하는 시스템이다. 그러나 GDSS-F2S에서 제공하는 이러한 두 가지 정보는 도적행위를 입증할 수 있는 법적 증거 자료로 미흡하다. 그래서 양식장의 지형을 고려한 도적행위의 유효한 대응책을 검토한 후, 하나의 해결방안으로 물체의 영상정보를 고려하였다. 앙식장을 침입하는 물체의 실시간 영상을 획득하기 위하여 0.0001 룩스(Lux)의 초저조도 CCD 카메라와 부가장치를 이용한 영상 획득 시스템을 구축하였다. 영상 획득 시스템을 부가한 GDSS-F2S의 현장실험 결과, 차량의 번호판과 외관, 사람의 행동과 특징 등을 주간은 물론 야간에도 선명하게 획득할 수 있었다. 따라서 영상획득 시스템을 부가하여 개선한 GDSS-F2S는 도적행위에 대한 충분한 법적 증거 제공이 가능하였다.

• 대한후두음성언어의학회지
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• 제21권1호
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• pp.37-41
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• 2010

Background and Objectives : Transient minor voice changes after thyroidectomy are not infrequent complaints even in cases without any evidence of recurrent laryngeal nerve damage. However, clinical course, diagnosis and management of such voice changes are not fully understood. This study aimed to evaluate the clinical characteristics of minor voice changes after thyroidectomy. We also tried to assess the significance and feasibility of superior laryngeal nerve monitoring and to find out the optimal evaluation tools for such voice changes after thyroidectomy. Materials and Method : Nine adult patients who received total thyroidectomy without evidence of recurrent laryngeal nerve injury were enrolled for this prospective study. Voice evaluations were performed preoperatively and 3 months postoperatively ; acoustic analyses including voice range profile, aerodynamic study, stroboscopic evaluation and subjective voice assessment with questionnaires. The external branch of superior laryngeal nerve was monitored by nerve stimulator after ligation of superior thyroidal vessels. Results: Four of nine patients complained their voice change at 3 months after the surgery. Three of them reported complete recovery of their voice at 6 months after the surgery. Acoustic analysis revealed significant decrease in their phonatory range especially with high tone loss. Questionnaires related to singing was more sensitive than previously well-known "voice handicap index". Stimulation of the superior laryngeal nerve was feasible in most of the cases (94.4%), but it failed to show any correlation with minor voice changes after thyroidectomy. Conclusion : Minor voice changes were not rare events during the first 6 month after thyroidectomy. Decrease in phonatory range with high tone loss and therefore, discomfort in singing was the most common finding. Superior laryngeal monitoring was feasible but it was not a sensitive tool for the prediction of minor voice change after thyroidectomy.

• 한국콘텐츠학회논문지
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• 제21권9호
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• pp.446-457
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• 2021

본 연구의 목적은 향후 의사가 되어 국민의 정신건강의 책임지게 될 국내 의과대학생의 우울에 관한 연구의 동향을 파악하여, 향후 연구에 대한 바람직한 방향성을 제시하고, 실질적인 예방 및 치료적 개입의 필요성을 재고하고자 하였다. 국가과학기술정보센터, 누리미디어, 한국교육학술정보, 한국학술정보, 국회도서관에서 의과대학생의 우울을 정량적으로 평가한 논문을 선별하여 최종 18편을 분석하였다. 그 결과 5년 이상 지속된 종단연구는 없었으며, 연구자 소속은 정신건강의학과가 52명(65.81%)으로 가장 많았고, 연구 대상자 학년은 본과 1학년(13편)이 가장 많은 것으로 나타났다. 측정도구는 BDI(7편, 35%)가 많이 사용되었고, 연구 통계방법으로는 독립표본 T검정(6편, 22.86%)가 가장 많이 사용되었다. 우울과 함께 연구된 변인들은 심리-생물-사회적 요인들로 나누어 살펴 보았다. 다양한 전문분야를 가진 연구자들이 다각적으로 연구에 접근하였으나, 의과대학생 우울에 대한 현상을 바라보는 것에 그쳤고, 우울에 대한 경로나 구조를 파악하거나 개입에 대한 연구는 없었다. 이러한 결과를 바탕으로 의대생들의 우울을 위한 실질적인 개입의 필요성에 대해 논의하였다.