• Title/Summary/Keyword: Enhance Effect

Search Result 4,698, Processing Time 0.033 seconds

Studies on the Enhancing Effect of Polymyxin B on the Antibodies Response of Enterobacterial Antigens (Pomyxin B의 장계세균항원(腸系細菌抗原)에 대(對)한 항체산생(抗體産生) 증강작용(增强作用)에 관(關)한 연구(硏究))

  • Lee, Jae-Koo
    • The Journal of the Korean Society for Microbiology
    • /
    • v.6 no.1
    • /
    • pp.29-40
    • /
    • 1971
  • Various kinds of antibiotics are generally believed to have inhibitory effects on the antibody response. However, as polymyxin B which belongs to the cyclic polypeptide group of antibiotic was found to have some enhancing effects on the antibody response of rabbits to enterobacterial common antigen(CA) under specified conditions, experiments were carried out on this problem with the following results. 1. When mixture of polymyxin B and CA derived from Salmonella typhimurium(STM) was treated 30 minutes at $37^{\circ}C$ and injected three times into rabbits by intravenous route, the antibody response to CA was weaker than rabbits injected CA only. 2. Mixture of polymyxin B and CA showed a marked antibody production when injected into rabbits primed with small amounts of heat-extracted antigen of STM, while the injection of CA alone showed low titers of response. 3. Mixture of polymyxin B and heat-extracted CA-containing antigen of Escherichia coli 014 also showed a increased antibody production than CA alone in rabbits primed with antigen of STM. 4. The effect of polymyxin B appeared in different ways. This antibiotic did not enhance the CA antibody response in rabbits primed with small amounts of E. coli 0111 and 055, but enhance in rabbits primed with Shigella flexneri. 5. No enhancing effect on the antibody response was observed by polymyxin B in rabbits primed with CA. 6. No enhancing effect on the antibody response was also noted in rabbits primed with STM antigen in case polymyxin B and CA were administered simultaneously but in veins of different places. 7. Bacitracin did not enhance the CA antibody response in primed rabbits with STM antigen, but neomycin slightly enhance the response. 8. Lipopolysaccharide showed no priming effect on the CA antibody response, and no enhancement of the CA antibody response in rabbits printed with STM. 9. The priming effect of STM antigen against CA antibody response was very weak as compared with the effect of CA derived from STM antigen.

  • PDF

Sensitivity Analysis of Numerical Weather Prediction Model with Topographic Effect in the Radiative Transfer Process (복사전달과정에서 지형효과에 따른 기상수치모델의 민감도 분석)

  • Jee, Joon-Bum;Min, Jae-Sik;Jang, Min;Kim, Bu-Yo;Zo, Il-Sung;Lee, Kyu-Tae
    • Atmosphere
    • /
    • v.27 no.4
    • /
    • pp.385-398
    • /
    • 2017
  • Numerical weather prediction experiments were carried out by applying topographic effects to reduce or enhance the solar radiation by terrain. In this study, x and ${\kappa}({\phi}_o,\;{\theta}_o)$ are precalculated for topographic effect on high resolution numerical weather prediction (NWP) with 1 km spatial resolution, and meteorological variables are analyzed through the numerical experiments. For the numerical simulations, cases were selected in winter (CASE 1) and summer (CASE 2). In the CASE 2, topographic effect was observed on the southward surface to enhance the solar energy reaching the surface, and enhance surface temperature and temperature at 2 m. Especially, the surface temperature is changed sensitively due to the change of the solar energy on the surface, but the change of the precipitation is difficult to match of topographic effect. As a result of the verification using Korea Meteorological Administration (KMA) Automated Weather System (AWS) data on Seoul metropolitan area, the topographic effect is very weak in the winter case. In the CASE 1, the improvement of accuracy was numerically confirmed by decreasing the bias and RMSE (Root mean square error) of temperature at 2 m, wind speed at 10 m and relative humidity. However, the accuracy of rainfall prediction (Threat score (TS), BIAS, equitable threat score (ETS)) with topographic effect is decreased compared to without topographic effect. It is analyzed that the topographic effect improves the solar radiation on surface and affect the enhancements of surface temperature, 2 meter temperature, wind speed, and PBL height.

A Brief Analysis of the Effect of track Improvement on Janghang and Jungang Line (장항선 및 중앙선 시설개량 개략적 효과 분석)

  • Lee, Kyung-Tae;Kim, Ick-Hee
    • Proceedings of the KSR Conference
    • /
    • 2009.05a
    • /
    • pp.822-827
    • /
    • 2009
  • Recently, a large amount of budget was invested in improving the railway tracks(double tracking, route improvement) of Janghang and Jungang line. However, further action to enhance the investment effect has been needed because the desired effect have not been obtained. This study was designed to evaluate the effect of track improvement briefly by examining the project summary of Janghang and Jungang line railway line improvement and analysing the change of the transport performance and revenue. The results of this study can be applied not only to establish an operation plan for maximizing the revenue of rail operation also to enhance an effect of track improvement.

  • PDF

New Technologies for Sow Nutrition and Management - Review -

  • Sohn, K.S.;Maxwell, C.V.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.12 no.6
    • /
    • pp.956-965
    • /
    • 1999
  • Genetic selection and sophisticated management technology have produced modern sows which excel in litter size and milk production. Recent research has identified nutritional innovations which may enhance productivity of the high producing sow. Selected research in three areas which have the potential to enhance reproductive performance are summarized in this report. First, preliminary evidence indicates that organic chromium may enhance litter size and conception rate. Secondly, high producing sows, particularly primiparous sows, required higher protein/lysine in late gestation and or lactation to optimize weaning weight and subsequent litter size. Valine and isoleucine, but not leucine, have been shown to enhance milk production. Phased feeding programs with diet cost partitioned toward gilts and away form parity 3 to 8 sows have been suggested as a means of improving reproductive performance in young sows. Lastly, recent research with sufficient sow numbers to document the effect of dietary fiber on reproductive performance has shown that sows fed fiber farrowed and weaned more pigs.

Application and Examination the Effect of mathematics Curriculum to Enhance Creative Problem Solving Abilities (창의적 문제해결력 중심의 수학 교육과정 적용 및 효과 분석)

  • 권오남;김정효
    • The Mathematical Education
    • /
    • v.39 no.2
    • /
    • pp.81-99
    • /
    • 2000
  • The Purpose of this study is to develop and implement an alternative secondary mathematics curriculum to enhance creative problem-solving abilities. The curriculum consisting of three main elements-content knowledge, process knowledge and creative thinking sills-as developed. Lessons were taught by a problem-based-learning method in an experimental group. In order to examine the effect of the curriculum, performance assessment was developed and used for pre and post.. There were significant group differences in the creative problem-solving abilities, so we could examine the effect of developed program and confirm the group differences in the attitude for lessons. But there were no significant group differences in motive for learning, a study skill and the achievement test.

  • PDF

Antioxidant enzyme activities and intracellular reactive oxygen intermediate (ROI) levels of flavonol quercetin in the presence of taurine on Bl6F10 murine melanoma cells.

  • Sim, Hue-Jeong;Kim, An-Keun
    • Proceedings of the Korean Society of Applied Pharmacology
    • /
    • 2003.11a
    • /
    • pp.66-66
    • /
    • 2003
  • Flavonoids are phenolic compounds widely distributed in wide variety of edible plants including leafy vegetables, fruits, beverages. Quercetin is one of bioflavonoid compounds and has anti-tumor effect by suppressing tumor growth in vitro and in vivo, including multiple biological effects by antioxidant and effective anti-inflammatory agent. The present study investigated whether quercetin can enhance antioxidant enzyme activities (glutathione peroxidase: GPX, superoxide dismutase : SOD, catalase: CAT) and intracellular reactive oxygen intermediate (ROI) levels in the presence of taurine on B16F10 murine melanoma cells. From this result, the antioxidant enzyme activities of quercetin in the presence of taurine was enhanced. In addition, the same treatments decreased intracellular reactive oxygen intermediate levels on B16F10 murine melanoma cells. Taken together, these results demonstrate that the antioxidant effect of quercetin can enhance in the presence of taurine and it might play an important role in anti-tumor effect.

  • PDF

Effect of Oral Health Beliefs and the Moderating Effect of Parents' Oral Health Behavior on Oral Health Promotion Behavior among Adolescents (청소년의 구강건강신념이 구강건강증진행위에 미치는 영향과 부모의 구강건강관리행동의 조절효과)

  • Park, Hyun-Min
    • The Korean Journal of Health Service Management
    • /
    • v.10 no.2
    • /
    • pp.133-144
    • /
    • 2016
  • Objectives : This study sought to identify the predisposing factors which influence the adolescent oral health enhancement behavior by analyzing controlling effects depending on the parents' oral health care behaviors in the relationship between the predisposing factors and adolescent behavior improvements which enhance oral health. Methods : A structured, self-administered questionnaire was given from July 6 through July 24, 2016. The collected data were analyzed with the SPSS 18.0 program. Results : Parents' oral health behaviors in terms of discipline and guidance showed a controlling effect in terms of importance (${\beta}$=.116) and benefits (${\beta}$=.133). In addition, the analysis showed that the parents' oral health care behavior had a controlling effect in terms of benefits (${\beta}$=.164) and susceptibility (${\beta}$=-.116). Conclusions : From the results of this study, the development of materials and education courses to lead to behavior changes are thought to be necessary in order to enhance the importance and benefits of the factors of oral health beliefs and to reduce psychological discomfort. Moreover, the role of parents with regard to desirable habits and beliefs to maintain oral health in their children is essential.

The Effect of Child Care Teachers' Positive Psychological Capital on Organizational Commitment: Mediating Effect of Job Stress (보육교사의 긍정심리자본이 조직몰입에 미치는 영향: 직무스트레스의 매개효과)

  • Jung Hee Moon;Youn Hee Kim;Seung-Min Song;Hye Soo Kim
    • Korean Journal of Childcare and Education
    • /
    • v.19 no.5
    • /
    • pp.21-43
    • /
    • 2023
  • Objective: The purpose of this study is to reduce job stress among child care teachers and enhance the quality of child care by examining the mediating effect of job stress in the relationship between positive psychological capital and the organizational commitment of child care teachers. Methods: The subjects of this study were 560 childcare teachers in Gyeonggi-do, and 465 questionnaires were ultimately analyzed. Descriptive statistics, correlation analysis, multiple regression analysis, and structural equation model were analyzed using SPSS 23.0 and AMOS 23.0. Results: As a result of the study, first, positive psychological capital of childcare teachers showed a positive correlation with organizational commitment. Additionally, both positive psychological capital and organizational commitment showed a negative correlation with job stress. Second, the direct effect of childcare teachers' positive psychological capital affecting organizational commitment was significant, and the direct effect of job stress affecting organizational commitment was also significant. It was found that positive psychological capital of childcare teachers significantly influenced organizational commitment through job stress. Conclusion/Implications: Therefore, providing an educational program to help childcare teachers enhance their positive psychological capital and foster commitment to the organization can significantly contribute to the improvement of childcare quality.

A Study on the Relationship between Self-Leadership and Teacher-Expertise in Kindergarten Teachers: Focusing on the Mediating Effect of the Teachers' Self-efficacy (유치원교사의 셀프리더십과 교사전문성의 관계: 교사효능감의 매개효과를 중심으로)

  • Choi, Mi Ae;Kim, Soon Young;Choi, Yang Mi
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.20 no.1
    • /
    • pp.248-258
    • /
    • 2019
  • The purpose of this study is to examine the relationship between self-leadership of teachers who conduct free-selection activities in kindergartens. In addition, we analyze the mediating effect of teacher self-efficacy. This study was conducted using data gathered through a survey conducted on 325 kindergarten teachers in Seoul and Gyeonggi-do areas from September 17 to 28, 2018. To analyze the data, the author used SPSS Statistics 22.0 and AMOS 20.0 programs to conduct reliability analysis, confirmatory factor analysis, correlation analysis, and structural equation modeling. The result of the verification of the hypothesis showed that self-leadership of kindergarten teachers who engaged in free-selection activities positively influenced self-efficacy. Self-leadership of teachers who employed free-selection activities had a positive effect on the expertise of teachers as well. Also, self-efficacy of kindergarten teachers positively affected expertise of these teachers. In addition, the self-leadership of kindergarten teachers mediated self-efficacy, so that the indirect effect on teacher expertise was statistically significant. Also, the direct effect of self-leadership on expertise of teachers was significant, which showed that the self-efficacy of the kindergarten teachers indirectly mediated the relationship between self-leadership and expertise of the teachers. This study showed that to enhance expertise of kindergarten teachers, this requires enhancing self-leadership of teachers. Also, in order to enhance the level of self-efficacy of teachers, necessary knowledge and skills that can enhance self-efficacy of these teachers in their working environment should be provided. In addition, someone who can play the role of active facilitator or helper is needed in order to enhance expertise of these teachers.