• 한국컴퓨터정보학회논문지
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• 제22권6호
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• pp.57-68
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• 2017

The Linked Open Data(LOD) cloud is quickly becoming one of the largest collections of interlinked datasets and the de facto standard for publishing, sharing and connecting pieces of data on the Web. Data publishers from diverse domains publish their data using Resource Description Framework(RDF) data model and provide SPARQL endpoints to enable querying their data, which enables creating a global, distributed and interconnected dataspace on the LOD cloud. Although it is possible to extract structured data as query results by using SPARQL, users have very poor in analysis and visualization of RDF data from SPARQL query results. Therefore, to tackle this issue, based on Formal Concept Analysis, we propose a novel approach for analyzing and visualizing useful information from the LOD cloud. The RDF data analysis and visualization technique proposed in this paper can be utilized in the field of semantic web data mining by extracting and analyzing the information and knowledge inherent in LOD and supporting classification and visualization.

• The Journal of the Acoustical Society of Korea
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• 제26권1E호
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• pp.21-26
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• 2007

In this paper, we propose a modified Viterbi algorithm to compensate for endpoint detection error during the decoding phase of an isolated word recognition task. Since the conventional Viterbi algorithm explores only the search space whose boundaries are fixed to the endpoints of the segmented utterance by the endpoint detector, the recognition performance is highly dependent on the accuracy level of endpoint detection. Inaccurately segmented word boundaries lead directly to recognition error. In order to relax the degradation of recognition accuracy due to endpoint detection error, we describe an unconstrained search of word boundaries and present an algorithm to explore the search space with efficiency. The proposed algorithm was evaluated by performing a variety of simulated endpoint detection error cases on an isolated word recognition task. The proposed algorithm reduced the Word Error Rate (WER) considerably, from 84.4% to 10.6%, while consuming only a little more computation power.

• Journal of information and communication convergence engineering
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• 제5권1호
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• pp.23-28
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• 2007

In this paper, we propose ATM switch structure including AAL type 2 switch which can efficiently transmit low-bit rate data, even if the network has many endpoints. We simulate the architecture of ATM switch fabric that is modeled in computer program and analyze the performance according to offered loads. ATM switch proposed in this paper can support cell switching for all types of AAL cells which consist of AAL type 1, AAL type 2, AAL type 3/4, and AAL type 5 cells. We propose two switch fabric methods; One supports the AAL type 2 cell processing per input port, the other global AAL type 2 cell processing for every input port. The simulation results show that the latter is superior to the former. But the former has a strong point for easy implementation and extensibility. The proposed ATM switch fabric architecture is applicable to mobile communication, narrow band services over ATM network.

• 한국독성학회:학술대회논문집
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• 한국독성학회 2003년도 추계학술대회
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• pp.132-132
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• 2003

In this GLP study, 4 study groups of 12 Sprague-Dawley (SD) rats/sex were given vehicle, or 1,000, 1,500, or 2,000 mg/kg/day Sophora Japonica Linne Seed Extract (SE) for 13 weeks. Standard endpoints in this study included mortality, clinical observations, body weight, food and water consumption, ophthalmoscopic examination, urinalysis, hematology, serum biochemistry, organ weights, gross anatomic pathology and histopathology.(omitted)

• Toxicological Research
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• 제25권1호
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• pp.9-15
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• 2009

Historically, research in toxicology has utilized non-human mammalian species, particularly rats and mice, to study in vivo the effects of toxic exposure on physiology and behavior. However, ethical considerations and the overwhelming increase in the number of chemicals to be screened has led to a shift away from in vivo work. The decline in in vivo experimentation has been accompanied by an increase in alternative methods for detecting and predicting detrimental effects: in vitro experimentation and in silico modeling. Yet, these new methodologies can not replace the need for in vivo work on animal physiology and behavior. The development of new, non-mammalian model systems shows great promise in restoring our ability to use behavioral endpoints in toxicological testing. Of these systems, the zebrafish, Danio rerio, is the model organism for which we are accumulating enough knowledge in vivo, in vitro, and in silico to enable us to develop a comprehensive, high-throughput toxicology screening system.

• Molecular & Cellular Toxicology
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• 제2권1호
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• pp.54-59
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• 2006

The toxicity of cadmium on Caenorhabditis elegans was investigated to identify sensitive biomarkers for environmental monitoring and risk assessment. Stress-related gene expression were estimated as toxic endpoints Cadmium exposure led to an increase in the expression of most of the genes tested. The degree of increase was more significant in heat shock protein-16.1, metallothionein-2, cytochrome p450 family protein 35A2, glutathione S-transferase-4, superoxide dismutase-1, catalase-2, C. elegans p53-like protein-1, and apoptosis enhancer-1 than in other genes. The overall results indicate that the stress-related gene expressions of C. elegans have considerable potential as sensitive biomarkers for cadmium toxicity monitoring and risk assessment.

• 통합자연과학논문집
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• 제9권1호
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• pp.10-15
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• 2016

In this paper the approximation methods of offset curve of conic with explicit error bound are considered. The quadratic approximation of conic(QAC) method, the method based on quadratic circle approximation(BQC) and the Pythagorean hodograph cubic(PHC) approximation have the explicit error bound for approximation of offset curve of conic. We present the explicit upper bound of the Hausdorff distance between the offset curve of conic and its PHC approximation. Also we show that the PHC approximation of any symmetric conic is closer to the line passing through both endpoints of the conic than the QAC.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2012년도 추계학술발표대회
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• pp.728-731
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• 2012

최근 분산 임베디드 시스템에서 실시간 데이터 교환에 대한 요구가 증가하면서 발간/구독(Publish/Subscribe) 기반의 데이터 중심 통신 미들웨어인 DDS(Data Distribution Service)에 대한 활용 분야가 증가하고 있다. 국방 분야의 시스템과 같은 고신뢰성을 요구하는 환경에서는 시스템 개발에 앞서, DDS 통신에 동적으로 참여하게 하는 디스커버리 과정의 안정적인 성능 검증을 요구한다. 성능 검증 및 신뢰성 있는 시스템 개발을 위해 실제 시스템과 유사한 환경에서 DDS의 디스커버리 사전시험(Prototype)을 수행하는 데, 이 때 많은 시간과 비용을 소요하게 된다. 본 논문에서는 DDS의 표준 프로토콜인 RTPS(Real-Time Publish-Subscribe)에서 필수로 요구하는 SDP(Simple Discovery Protocol)를 이용하여 디스커버리 시간을 추정할 수 있는 계산식을 제안한다. 계산식은 참여자(Participant) 수를 이용한 연결 쌍(pair)의 수식과 단말개체(Endpoints) 수를 이용한 가중치(weight) 수식을 이용하며, 실제 상용 DDS 미들웨어를 이용하여 유형별로 DDS 디스커버리 시험을 수행한 결과와 비교하여 계산식을 실제로 사용할 수 있음을 보인다.

• Bulletin of the Korean Chemical Society
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• 제12권3호
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• pp.334-342
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• 1991

To investigate the phase equilibria and structural properties of microemulsions, we study a simple phenomenological model on the basis of the cubic lattice cell with which the oil- and water-filled cells are connected one another, respectively. The surfactant is assumed to be insoluble in both oil and water, and to be adsorbed at the oil-water interface. The Schulman condition, according to which the lateral pressure of the surfactant layer is compensated by the oil-water interfacial tension, is found to hold to good approximation in the middle-phase microemulsion. Our results show that the oil- and water-filled domains in that microemulsion are about 50-150 $\AA$ across, and depend sensitively on the curvature parameters. The phase diagram is not symmetric in this model. It may be asymmetrized intrinsically by non-equivalency of oil and water. The two- and tree-phase equilibria including critical points and critical endpoints are found.

• 한국임상약학회지
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• 제18권2호
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• pp.114-119
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• 2008

Alendronate is a bisphosphonate that selectively inhibits osteoclast-mediated bone resorption. Dosing convenience is an important element for the enhancement of patient compliance and the effective management of osteoporosis. The purpose of this study was to compare the effectiveness and compliance among alendronate pharmaceutical products (oral once-weekly alendronate 70 mg, daily alendronate 10 mg, and once-weekly alendronate 70 mg with Vitamin $D_3$ 2800 IU) in terms of the change in bone mineral density (BMD), biochemical markers, and compliance estimates. A retrospective chart review was conducted in patients with osteoporosis who received alendronate 70 mg (Group 1), alendronate 10 mg (Group 2), or alendronate 70 mg with Vitamin D3 2800 IU (Group 3) at the endocrinology department of a hospital in Korea from Jan. 1, 1998 to Mar. 31, 2008. The primary endpoints were the increases in spine antero-posterior BMD T-score and femur trochanter BMD T-score, and the compliance of alendronate products. Secondary endpoints included changes in bone turnover-related biochemical markers including bone-specific alkaline phosphatase, urinary N-terminal telopeptides (NTX) and osteocalcin, and in serum vitamin $D_3$ concentration. There was no statistical difference in the BMD increase among the three alendronate products; spine BMD T-score increased by $0.49{\pm}0.52$, $0.39{\pm}0.48$ and $0.50{\pm}0.41$, and femur trochanter BMD T-score by $0.29{\pm}0.42$, $0.21{\pm}0.53$ and $0.24{\pm}0.22$ in Group 1, 2 and 3, respectively. With respect to the increases in femur trochanter BMD T-score and the decreases in NTX and osteocalcin, 70 mg once-weekly group was remarkably superior to 10 mg daily group (p < 0.05) The compliance of 70 mg once-weekly group was significantly higher than that of 10 mg daily treatment group (p < 0.001). In conclusion, all three alendronate treatment groups were equivalent in effectiveness, and the compliance of 70 mg once-weekly group was better than that of 10 mg daily treatment group.