• Korean Journal of Ecology and Environment
• /
• v.40 no.2
• /
• pp.244-253
• /
• 2007

In this study, mortality, body wet weight, health assessment, and short-term behavioral mode were observed to determine the effects of ultrasound on the ecological response of the carp Cyprinus carpio. Mortality in the treatments was less than 5% during ultrasound exposure (31 dB re 1 ${\mu}Pa$, $14{\sim}15$ kHz) and there were no significant differences among the replicates (P>0.05). The treatments, based on mean wet weight, exhibited greater effect than the controls, but the magnitude of the differences was not large. Skins and tail fins of some test animals exposed to the controls and intensive treatment groups had light injury such as hemorrhaging, whereas, damages in other organs such as eyes, other fins, parasites, thymus, and gills were not observed (P>0.05). Sudden stimuli in low intensity at a short distance caused a directional avoidance of the fish from the sound. However, the carp exposed to ultrasound at the large scale field was not observed clear behavior changes. Overall results suggest that fish exposed to the low-intensity ultrasound had no serious stress during the tests.

• The Journal of Korean society of community based occupational therapy
• /
• v.9 no.2
• /
• pp.23-31
• /
• 2019

Objective : The purpose of this study is to repeatedly conduct task-oriented training in scopolamine-induced dementia rats and as a result observe changes in the content of acetylcholine, a marker of cognitive function and central nervous system plasticity, to identify the improvement effect of dementia. Methods : It consisted of two groups. One group I was that did not perform task-oriented training in scopolamine-induced dementia rats and the other group II was that performed task-oriented training. Task-oriented training involved stretching, grasping and moving arms and walking obstacles on the legs. We performed a quantified passive avoidance test in the measurement of memory for cognitive function and compared the change in the content of acetylcholine for the plasticity of the central nervous system. Results : The results of the study are as follows: First, there was a significant improvement in cognitive function since the 4th days after task-oriented training of scopolamine-induced dementia rats(.00). Second, task-oriented training applied to scopolamine-induced dementia rats showed a significant increase in acetylcholine content. Conclusion : In this study, task-oriented training, which is often performed on senile dementia patients during occupational therapy intervention, was scientifically demonstrated in scopolamine-induced dementia rats by enhancement of cognitive function through memory improvement and increase in the content of acetylcholine confirming central nervous system plasticity.

• Korean Journal of Food Science and Technology
• /
• v.47 no.6
• /
• pp.779-784
• /
• 2015

This study was conducted to investigate the effect of herbs on memory improvement by focusing on their cholinergic functions in Tg2576 mice. Seven herbs were used to obtain extracts by using alcohol and water. In screening test for cholinergic activities of the extracts, acetylcholinesterase (AChE) activity was highly inhibited in Oenanthe javanica alcohol extract (OJAE, 18.76%) as compared with the others. The OJAE-treated Tg2576 (Tg-OJAE) groups showed the statistically significant increases of latency time in passive avoidance test. Also, it was found that the concentration of $A{\beta}1-42$ was significantly reduced in Tg-OJAE groups compared to non-treated Tg2576 groups. In the additional enzyme test, it was found that $IC_{50}$ of OJAE was $991.77{\mu}g/mL$ and OJAE acted as an uncompetitive inhibitor of AChE. Therefore, it seemed that OJAE can be used for the development of processed foods for memory improvement.

• Journal of Venture Innovation
• /
• v.5 no.4
• /
• pp.57-74
• /
• 2022

The purpose of this study is to verify the influence of SME members' motivation and creative working environment on innovative behavior and to see differences according to individual absorptive capacity. As a research method for this, 350 copies were collected by requesting a specialized research company for employees who have worked at SMEs for more than a year, and research models and hypotheses were verified with SPSS 28 and Smart PLS 3. As a result of the study, approach motivation and creative work environment had a positive effect on individual innovation behavior, which showed significant differences according to individual absorptive capacity. The implications of this study are summarized as follows. First, for innovative organizational management in SMEs where human resources are more important than physical resources, SMEs need to provide a creative working environment and motivate members to derive positive innovative behavior. Second, innovation behavior differs depending on personal absorptive capacity, and innovation behavior becomes the subject of corporate growth, indicating that various interests and support are needed to increase personal absorptive capacity along with positive motivation for members.

• Korean Journal of Culture and Social Issue
• /
• v.11 no.2
• /
• pp.1-29
• /
• 2005

This research examined the effect of social anxiety on psychological adaptation. Higher the social anxiety, higher in neurotism & worry but lower in Psychological Well-Being and Satisfaction with Life. Among the sub-factors of social anxiety, negative adaptation was significantly predicted by personal anxiety. However positive adaption were predicted by personal anxiety, fairness anxiety and future anxiety. Among the sub-dimensions of social anxiety, negative and positive adaptation were significantly predicted only by anticipatory anxiety. And there were significant positive correlations between social anxiety and aggressive/give-up response. Particularly, personal anxiety was the predictor of aggressive response, but safe anxiety and political anxiety were the predictors of give-up response. The dimension predicted the aggressive/give-up response was anticipatory anxiety dimension. Finally, respondents used problem solving stress coping strategy most. But the respondents whose social anxiety level especially safe anxiety and political anxiety were high used wishful thinking strategy. Moreover higher the reactive anxiety level, more frequently used the avoidance coping strategy.

• Journal of Intelligence and Information Systems
• /
• v.27 no.3
• /
• pp.113-137
• /
• 2021

According to the clear potential of mobile banking growth, many studies related to this are being conducted, but in Korea, it is concentrated on the analysis of technical factors or consumers' intentions, behaviors, and satisfaction. In addition, even though it has a strong customer base of 20s, there are few studies that have been conducted specifically for this customer group. In order for mobile banking to take a leap forward, a strategy to secure various perspectives is needed not only through research on itself but also through research on external factors affecting mobile banking. Therefore, this study analyzes impulsiveness, credit card use, and SNS addiction among various external factors that can significantly affect mobile banking in their 20s. This study examines whether the relationship between impulsiveness and mobile banking usage depends on whether or not a credit card is used, and checks whether a customer's impulsiveness is possible by examining whether a credit card is used. Based on this, it is possible to establish new standards for classification of marketing target groups of mobile banking. After finding out the static or unsuitable relationship between whether to use a credit card and impulsiveness, we want to indirectly predict the customer's impulsiveness through whether to use a credit card or not to use a credit card. It also verifies the mediating effect of SNS addiction in the relationship between impulsiveness and mobile banking usage. For this analysis, the collected data were conducted according to research problems using the SPSS Statistics 25 program. The findings are as follows. First, positive urgency has been shown to have a significant static effect on mobile banking usage. Second, whether to use credit cards has shown moderating effects in the relationship between fraudulent urgency and mobile banking usage. Third, it has been shown that all subfactors of impulsiveness have significant static relationships with subfactors of SNS addiction. Fourth, it has been confirmed that the relationship between positive urgency, SNS addiction, and mobile banking usage has total effect and direct effect. The first result means that mobile banking usage may be high if positive urgency is measured relatively high, even if the multi-dimensional impulsiveness scale is low. The second result indicates that mobile banking usage rates were not affected by the independent variable, negative urgency, but were found to have a significant static relationship with negative urgency when using credit cards. The third result means that SNS is likely to become addictive if lack of premeditation or lack of perseverance is high because it provides instant enjoyment and satisfaction as a mobile-based service. This also means that SNS can be used as an avoidance space for those with negative urgency, and as an emotional expression space for those with high positive urgency.

• Toxicological Research
• /
• v.17
• /
• pp.47-57
• /
• 2001

Alzheimer's disease (AD) is the most common cause of dementia in the elderly, and its pathology is characterized by the presence of numerous numbers of senile plaques and neurofibrillary tangles. Several genetic and transgenic studies have indicated that excess amount of $\beta$-amyloid protein (A$\beta$) is produced by mutations of $\beta$TEX>$\beta$-amyloid precursor protein and causes learning impairment. Moreover, $A\beta$ has a toxic effect on cultured nerve cells. To prepare AD model animals, we have examined continuous (2 weeks) infusion of $A\beta$ into the cerebral ventricle of rats. Continuous infusion of $A\beta$ induces learning impairment in water maze and passive avoidance tasks, and decreases choline acetyltransferase activity in the frontal cortex and hippocampus. Immunohistochemical analysis revealed diffuse depositions of $A\beta$ in the cerebral cortex and hippocampus around the ventricle. Furthermore, the nicotine-evoked release of acetylcholine and dopamine in the frontal cortex/hippocampus and striatum, respectively, is decreased in the $A\beta$-infused group. Perfusion of nicotine (50 $\mu\textrm{M}$) reduced the amplitude of electrically evoked population spikes in the CA1 pyramidal cells of the control group, but not in those of the $A\beta$-infused group, suggesting the impairment of nicotinic signaling in the $A\beta$-infused group. In fact, Kd, but not Bmax, values for ［$^3H$］ cytisine binding in the hippocampus significantly increased in the $A\beta$-infused rats. suggesting the decrease in affinity of nicotinic acetylcholine receptors. Long-term potentiation (LTP) induced by tetanic stimulations in CA1 pyramidal cells, which is thought to be an essential mechanism underlying learning and memory, was readily observed in the control group, whereas it was impaired in the $A\beta$-infused group. Taken together, these results suggest that $A\beta$ infusion impairs the signal transduction mechanisms via nicotinic acetylcholine receptors. This dysfunction may be responsible, at least in part, for the impairment of LTP induction and may lead to learning and memory impairment. We also found the reduction of glutathione- and Mn-superoxide dismutase-like immunoreactivity in the brains of $A\beta$-infused rats. Administration of antioxidants or nootropics alleviated learning and memory impairment induced by $A\beta$ infusion. We believe that investigation of currently available transgenic and non-transgenic animal models for AD will help to clarify the pathogenic mechanisms and allow assessment of new therapeutic strategies.

• Journal of the Ergonomics Society of Korea
• /
• v.36 no.5
• /
• pp.447-458
• /
• 2017

Objective: The purpose of this study is to present the basic guidelines for preventing human error by measuring and analyzing the risk of collision perceived by the ship operator in the collision risk situation by using Korea Coast Guard patrol ships. Background: In the last 5 years, 97.5% of the causes of ship collision occurred at the sea was caused by human factors. However, the rate of marine accidents due to human error has not been reduced yet. Experiments and researches on the ship operators using the ships in actual operation are rarely performed. Method: Using two K.C.G Ships on the sea, the ship measured by 30 persons who are the subject of the ship (ship operator) when both ships approach and the relative distance gradually decreases in four encounter situations, perceived ship collision risk (PSCR) data were analyzed by statistical analysis. Results: The age and boarding career of the ship operator in the situation of ship collision risks encountered a negative impact on perceived collision risk in all four opposing encounter situations S1 ($000^{\circ}$), S2 ($045^{\circ}$), S3 ($090^{\circ}$) and S4 ($135^{\circ}$) respectively. That is, the higher the age of the ship operator, the lower the perceived risk of collision and the lower the age, the higher the risk of collision. Also, there was a difference between the average of group A (20~30 years) and group B (40~50 years) according to age of the ship operators at $000^{\circ}$, $045^{\circ}$ and $090^{\circ}$ and there was no difference at $135^{\circ}$. The mean difference of the experience of boarding career was also significantly different between group A (less than 4 years) and group B (more than 5 years), but there was no significant difference at $135^{\circ}$. Conclusion: The results showed that age and boarding career of the ship operators had negative impact on perceived collision risk and there was a difference in perceived risk of collision according to age and abundance of boarding career. As a result, by focusing on the ship operators who are in the age group of 20~30 years old and have less than 4 years of experience in boarding the ship. It is expected that the effect of prevention of marine accidents can be expected by avoiding collision avoidance. Application: The results of this study can be used as policy data of related organizations to prevent human error of ship operators and as training data of training institutes.

• Korean Journal of Food Science and Technology
• /
• v.45 no.2
• /
• pp.257-261
• /
• 2013

Rat pheochromocytoma cells (PC12) and mice were utilized as in vitro and in vivo models to determine the neuroprotective effects of a 70% acetone extract of black soybean seed coat (BSSCE). BSSCE showed higher total phenolic contents than other extracts. Intracellular reactive oxygen species accumulation from $H_2O_2$ treatment of PC12 cells was significantly reduced when BSSCE was present in the media compared to PC12 cells treated with $H_2O_2$ only. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium-bromide (MTT) reduction assay and lactate dehydrogenase assay also showed significantly increased protective effects in PC12 cells. In addition, BSSCE improved the in vivo cognitive ability against amyloid beta peptide-induced neuronal deficits.

• The Journal of the Korea Contents Association
• /
• v.13 no.8
• /
• pp.152-159
• /
• 2013

Delinquency young people committed society as evolves is also increasing rapidly. Juvenile delinquency that occurred recently is serious. As a result, young people are feeling fear of delinquency. Fear of delinquency young people feel, a major impact on the personality development of the youth of the period of growth. In particular, the violent delinquency, to give a physical impact, damage youth receives is large. As well as physical damage to people in and around the juvenile victims, given the damage mental serious form, fear violent delinquency has been shown in many previous studies. Therefore, in this study you have the purpose to study the effects on the reaction of juvenile victims for fear of delinquency caused by the delinquency of violence. Set randomly on campus and external experience and damage directly or indirectly, are classified into action evasive action defensive reaction of fear by delinquency, factors that affect the risk caused by violent delinquency, Daegu after conducting a survey of high school students in general in the areas in which we tested the hypothesis. As a result of the verification, exerting a significant influence in order to act defensive becomes clear, experience of direct damage and experience of damage indirect fear of delinquency, avoided experience of direct damage it was found to exert a significant effect on to the action manner.