• Title/Summary/Keyword: ERC

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Clinical Significance of Segmental Parenchymal Excretion Delay on Tc-99m DISIDA Hepatobiliary Scan (Tc-99m DISIDA 간담도 신티그라피에서 간 실질의 분절형 배설지연의 임상적 의의)

  • Kang, Do-Young;Ryu, Jin-Sook;Moon, Dae-Hyuk;Lee, Sung-Koo;Kim, Myung-Hwan;Lee, Hee-Kyung
    • The Korean Journal of Nuclear Medicine
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    • v.32 no.2
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    • pp.161-167
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    • 1998
  • Purpose: Segmental parenchymal excretion delay on Tc-99m DISIDA scan is caused by intrahepatic bile duct obstruction. However, the diagnostic value for intrahepatic bile duct obstruction is unknown. We conducted this study to assess the positive predictive value of segmental excretion delay for the diagnosis of intrahepatic bile duct obstruction, and additional benefit over other noninvasive radiologic studies. Materials and Methods: The study population consisted of 43 patients (48 scans) who showed segmental parenchymal excretion delay on Tc-99m DISIDA scan. The results of abdominal CT or ultrasonography, which was done within 1 month of Tc-99m DISIDA scan, were compared with scintigraphic findings. Results: The etiology of segmental parenchymal excretion delay was determined by ERC or PTC in 31 scans, and follow-up studies in 13 scans. No causes were identified in 4 scans. The positive predictive value of segmental parenchymal excretion delay for intrahepatic bile ductobstruction was 92% (44/48). On the other hand, 13% (5/38) of CT and 28% (5/18) of ultrasonography were normal. In 18% (7138) of CT and 17% (3/18) of ultrasonography, only intraheipatic bile duct dilatation was noted without any diagnostic findings of intrahepatic bile duct obstruction. Conclusion: Segmental parenchymal excretion delay on Tc-99m DISIDA scan had a high positive predictive value for the diagnosis of intrahepatic bile duct obstruction. Tc-99m DISIDA scan may be useful for the diagnosis of intrahepatic bile duct obstruction, especially in patients with nondiagnostic CT or ultrasonography. The diagnostic usefulness need to be confirmed by further prospective studies.

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A Study on the Design Parameters of a Gasket and Innercase of a Refrigerator to Reduce Dew Generation on the Outer Surface (표면의 이슬 맺힘 저감을 위한 냉장고 가스켓 및 냉동냉장실 내벽 구조개선에 관한 연구)

  • Kang, Seok-Hoon;Kim, Seong-Jin;Kim, Ju-Hwan;Min, June-Kee;Sohn, Chang-Min;Park, Sang-Hu
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.4
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    • pp.457-463
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    • 2012
  • Current refrigerators are designed to have thin doors and walls to facilitate user convenience and increase inner storage space. However, the thin doors and walls gives rise to the problem of dew generation on the outer surface of a refrigerator due to a large critical temperature difference between the outer wall and the room air; So far, an electric heater is commonly used for making the dew to evaporate; in this case, the heater inevitably requires additional electrical power. We propose a new approach to reduce the dew generation in a refrigerator by redesigning the gasket and varying the thickness of the inner case of the refrigerator. The results of simulations performed in this study indicate that the surface temperature in the region where dew was generated was increased by approximately $0.39{\sim}3.07^{\circ}C$ without the use of a heater.

Analysis of Motivational Factors of Korean Women with Children to become Mumpreneurs (한국 주부 창업자의 창업 동기요인 분석)

  • Lee, Jae Hong;Lee, Bong Hwan
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.13 no.2
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    • pp.79-90
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    • 2018
  • A wide range of challenges and obstacles still exist for "mumpreneurs" in creating or developing their business ventures. It is important to investigate the factors regarding why many mothers choose to become self-employed and partially abandon the benefits offered by traditional employment. This study focus on the individual, but an implied positive relationship also exits between motivational factors and mumpreneurs in Korea. Thus, four factors in this study - push, pull, environmental, and financial factor - raise the practical implications regarding the motivational factors of women entrepreneurial challenges in Korea. This study's findings also consider the nature and changes of Korean mumpreneurs' motivational factors, their challenges, and attitudes as business owners in Korean labor markets. This study's findings suggest that a combination of push and pull factors could similarly trigger new business ownership. The empirical contrast in such variables as motivations or barriers to mumpreneurship, in realities provide a superior understanding of women's tendency or willingness toward business creation, as they struggle to survive in the Korean labor market. They tend to start their own businesses to gain more responsibilities in both work and their families, and want to manage their own lives to contribute as capable members of society. Therefore, any Korean mother, regardless of any industry-specific experience, wants to use entrepreneurship as a shortcut to satisfy her need for self-fulfillment. The general motivational factors for becoming a mumpreneur exist among both external and internal situations. The circumstances beyond their control, such as job termination or unemployment, compel these mothers into the workforce due to their responsibility toward their families, but they simultaneously dream of self-achievement and development. Most mumpreneurs in Korea also want to demonstrate their potential and achieve societal recognition as well as increase in property.

Demand Surveys for Big Research Facilities and Equipments to Advance National S&T Research Infrastructure (과학기술 하부구조 선진화를 위한 대형 연구장비의 수요 조사)

  • 권용수;민철구
    • Proceedings of the Technology Innovation Conference
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    • 1997.12a
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    • pp.159-176
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    • 1997
  • This paper deals with demand surveys for big science and technology research facilities and equipments to advance national S'||'&'||'T research infrastructure. We perform surveys thrice based on applied Delphi method on the future demand of big S'||'&'||'T research facilities and equipments among Korean scientists and engineers. We employ the concept of big S'||'&'||'T research facilities and equipments as follows: \circled1 The operating size of it is equivalent to that of an institute or research center, and/or \circled2 The users in various disciplines are many, and/or \circled3 The application areas or spill-over effects are large, and/or \circled4 The scale and scope of research objects is equivalent to that of mega science area such as earth.oceanography.space, and/or \circled5 The expenses for installing and operating it are to be supported by government, and/or \circled5 The facilities are expected as necessary for international joint research, and/or \circled7 It is necessary for promoting creative basic science and developing creative technology. We ask the respondents to answer the following questionnaire: - How to prioritize the equipments according to the degree of importance\ulcorner $\square$ Promotion of basic science and mega science, the development of the technologies to enhance the public welfare, the competitiveness of industrial technologies, the job creation for the S'||'&'||'T personnel, and international cooperation. - Who should be in charge of acquisition and operation of the equipments\ulcorner $\square$ Industry, Government Research Institutes, Academy, ERC and SRC. - When shall we acquire the equipment\ulcorner $\square$ Within 2000, 2002, 2007, 2012, and 2017. - How shall we acquire the equipments\ulcorner $\square$ International Joint Development, Domestic Development, Acquisition from Overseas, - How much will the equipment generate spill-over effects to national competitiveness\ulcorner $\square$ Promotion of basic science, contribution to the economy, supply of S'||'&'||'T personnel, and international cooperation. We suggest the following equipments as prioritized candidates after consulting the officers from MOST, MOE, MIC, MOEN and experts from KBSI and STEPI:(table omitted) where, #1, Korea Advanced Liquid Metal Reactor, #2. 800 MHz Superconduction Fourier-Transform Nuclear Magnetic Resonance Spectrometer, #3. Ion Accelerator, #4. Seismic Test Facility, #5. Transonic Wind Tunnel, #6. Radio Telescope for Very Long Baseline Interferometer, #7. 3000t Universal(or Large Structure) Testing Machine, #8. Compost Facility or Plasma Pyrolysis Facility.

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A Numerical Analysis of the Behavior of Liquid Film Around a Rotating Cylinder (회전하는 실린더 주변 액막의 거동에 대한 수치해석적 연구)

  • Lee, Sang-Hyuk;Lee, Jung-Hee;Hur, Nahm-Keon;Seo, Young-Jin;Kim, In-Cheol;Lee, Sung-Jin
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.35 no.5
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    • pp.481-486
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    • 2011
  • It is important to predict the behavior of a liquid film around a rotating cylinder in the film coating process of the steel industry. When the cylinder rotates, the behavior of the liquid film on the rotating cylinder surface is influenced by the cylinder diameter, the rotation speed, the gravitational force, and the fluid properties. These parameters determine the liquid film thickness and the rise of the film on the cylinder surface. In the present study, the two-phase interfacial flow of the liquid film on the rotating cylinder were numerically investigated by using a VOF method. For various rotation speeds, cylinder diameters and fluid viscosities, the behavior of liquid film on the rotating cylinder were predicted. Thicker film around the rotating cylinder was observed with an increase in the rotation speed, cylinder diameter, and fluid viscosity. The present results for the film thickness agreed well with available experimental and analytical results.

Development of the auto leveling mechanism for side-by-side refrigerator doors (양문형 냉장고 도어의 자동 단차 맞춤 메커니즘 개발)

  • Weng, Lei;Yun, Jae-Deuk;Jung, Yoong-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.7
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    • pp.3165-3174
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    • 2012
  • Recently the increasingly common large refrigerator is the side by side(SBS) refrigerator whose freezing chamber and refrigerating chamber are set side by side. But one of the biggest dissatisfaction of customers about SBS refrigerator is that the two doors don't meet the same height when they are closed. It is called door height difference(DHD). The main cause of DHD is the unevenness of floor on which a refrigerator is placed or the cabinet deformation caused by long time use. When the DHD is confirmed, the customer or maintenance personnel use wrench to adjust the support screw to make the refrigerator to reach the horizontal position. But for big refrigerator, it is not only difficult for women and old people who don't have enough force to adjust it, but also inappropriate to require customers to do this job. In order to resolve this problem, this research proposes a new mechanism which can detect the DHD and adjust two doors to the same height automatically. The adjustment would be completed during opening and closing the doors, avoid needing hard operation with wrench by hand.

Development of a Multi-step Stamping Process for the Effective Fabrication of a Thin Sheet for High Aspect Ratio Corrugated Structures (고세장비 연속주름을 갖는 박판구조물 제작을 위한 다단성형공정 개발)

  • Choi, Sung-Woo;Park, Sang-Hu;Jeong, Ho-Seung;Min, June-Kee;Jeong, Jae-Hun;Cho, Jong-Rae;Kim, Hyun-June;Willians, Paul
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.34 no.2
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    • pp.219-226
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    • 2010
  • The stamping process is widely used in fabricating various sheet-parts for vehicle, airplane, and electronic devices due to its low processing cost and high productivity. Recently the use of thin sheets with corrugated structures has rapidly increased for the production of energy devices, e.g., heat exchangers and fuel cells. However, it is very difficult to make corrugated structures directly in the stamping process due to their geometrical complexity. To solve this problem, this paper proposes a multi-step stamping process with a combined heat treatment process: a sequence of the first stamping, heat treatment, and second stamping. By multi-stamping, we obtained successful results in fabricating very thin corrugated structures with thicknesses of $100{\mu}m$; these are applicable as part of a plate-type heat exchanger.

Genetic diversity and selection of Tibetan sheep breeds revealed by whole-genome resequencing

  • Dehong Tian;Buying Han;Xue Li;Dehui Liu;Baicheng Zhou;Chunchuan Zhao;Nan Zhang;Lei Wang;Quanbang Pei;Kai Zhao
    • Animal Bioscience
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    • v.36 no.7
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    • pp.991-1002
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    • 2023
  • Objective: This study aimed to elucidate the underlying gene regions responsible for productive, phenotypic or adaptive traits in different ecological types of Tibetan sheep and the discovery of important genes encoding valuable traits. Methods: We used whole-genome resequencing to explore the genetic relationships, phylogenetic tree, and population genetic structure analysis. In addition, we identified 28 representative Tibetan sheep single-nucleotide polymorphisms (SNPs) and genomic selective sweep regions with different traits in Tibetan sheep by fixation index (Fst) and the nucleotide diversity (θπ) ratio. Results: The genetic relationships analysis showed that each breed partitioned into its own clades and had close genetic relationships. We also identified many potential breed-specific selective sweep regions, including genes associated with hypoxic adaptability (MTOR, TRHDE, PDK1, PTPN9, TMTC2, SOX9, EPAS1, PDGFD, SOCS3, TGFBR3), coat color (MITF, MC1R, ERCC2, TCF25, ITCH, TYR, RALY, KIT), wool traits (COL4A2, ERC2, NOTCH2, ROCK1, FGF5, SOX9), and horn phenotypes (RXFP2). In particular, a horn-related gene, RXFP2, showed the four most significantly associated SNP loci (g. 29481646 A>G, g. 29469024 T>C, g. 29462010 C>T, g. 29461968 C>T) and haplotypes. Conclusion: This finding demonstrates the potential for genetic markers in future molecular breeding programs to improve selection for horn phenotypes. The results will facilitate the understanding of the genetic basis of production and adaptive unique traits in Chinese indigenous Tibetan sheep taxa and offer a reference for the molecular breeding of Tibetan sheep.