• Title/Summary/Keyword: E-normal

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DISTRIBUTION OF NONCOLLAGENOUS PROTEIN DURING REPAIR OF PARTIALLY RESECTED CONDYLAR CARTILAGE AND BONE;SEM AND IMMUNOHISTOCHEMICAL STUDY (하악두(下顎頭)의 부분절제(部分切除)된 연골(軟骨) 및 골(骨)의 치유과정(治癒課程)에서 비교원성(非膠原性) 단백질(蛋白質) 분포(分布)에 관(關)한 연구(硏究);주사전자현미경적(走査電子顯微鏡的) 및 면역조직화학적(免疫組織化學的) 연구(硏究))

  • Kim, Myung-Hwan;Lee, Sang-Chull
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.18 no.3
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    • pp.411-427
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    • 1996
  • The purpose of this study was to observe the healing process and the distribution of fibronectin in injured condylar cartilage and bone by using LM and SEM. In order to perform this study, 40 male rat, weighing about 250g were selected. Under general anesthesia with Pentobarbital sodium, condylar cartilage and neck bone were resected. Then, the wound was irrigated with saline and closed with 5-0 chromic catgut and 4-0 silk by layer-to-layer suturing. The experimental rats were sacrificed by perfusion with 3% paraformaldehyde at 1st and 4th week after operation. The condylar process and surrounding tissues were cut, demineralized, dehydrated and embedded in paraffin. The histological observation of the specimens in LM level was performed after H-E stain and Azan stain. For localization of fibronectin, immunostaining was achieved by the avidin-biotin complex method. To study the change on condylar surface, the specimens were dehydrated, dried, gold coated and were observed with a scanning electron microscope(Hitachi S-2300). The results were as follows ; 1. The cartilage group and the bone group were repaired with epiphyseal cartilage layer on the cut surface as the normal control group. 2. The cut surface was repaired more quickly in the cartilage group than in the bone group. 3. Chondrocytes, diferentiated during healing, were stained strongly to anti-fibronectin, and fibronectin was supposed to participatein chondrocyte differentiation and cartilagenous matrix formation. 4. Fibronectin was distributed more in the new bone than in the old bone, and the osteoblasts surrounding it were also stained strongly. Fibronectin was supposed to participate in new bone matrix formation. 5. Fibronectin is supposed to be associated with the differentiation, migration and adhesion of chondrocyte and osteoblast and to participate in endochondral bone formation.

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Creep Behavior of High-Strength Concrete with Nylon Fibers at Elevated Temperatures (고온을 받은 나일론 섬유 보강 고강도 콘크리트의 크리프 거동)

  • Kim, Young-Sun;Lee, Tae-Gyu;Kim, Woo-Jae;Kim, Gyu-Yong
    • Journal of the Korea Concrete Institute
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    • v.23 no.5
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    • pp.627-636
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    • 2011
  • Recently, to prevent explosive spalling of high-strength concrete (HSC) members, the usage of nylon fiber instead of polypropylene fiber has increased. Past experimental studies have been conducted to examine the spalling and mechanical properties of HSC with nylon fibers when exposed to elevated temperature. However, the previous studies on HSC with nylon fibers subjected to high temperatures were performed only on the properties such as spalling, compressive strength, and elastic modulus rather than investigations on to the behaviors such as thermal strain, total strain, steady state creep, and transient creep. Therefore, in this study thermal strain, total strain, steady state creep, and transient creep of HSC mixed with nylon fibers with water to binder ratio of 0.30 to 0.15 were tested. The experimental results showed that nylon fibers did not affect the performance of HSC with nylon fibers at high temperatures. However, HSC with nylon fibers generated a larger transient creep strain than that of HSC without fibers and normal strength concrete.

The Impact of Preoperative Low Body Mass Index on Postoperative Complications and Long-term Survival Outcomes in Gastric Cancer Patients

  • Kim, Chang Hyun;Park, Seung-Man;Kim, Jin-Jo
    • Journal of Gastric Cancer
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    • v.18 no.3
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    • pp.274-286
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    • 2018
  • Purpose: The aim of this study was to investigate the impact of preoperative low body mass index (BMI) on both the short- and long-term outcomes in patients with gastric cancer. Materials and Methods: A total of 510 patients with gastric cancer were divided into the following 3 groups: low BMI group (${\leq}18.5kg/m^2$, n=51), normal BMI group ($18.6-24.9kg/m^2$, n=308), and high BMI group (${\geq}25.0kg/m^2$, n=151). Results: There were significantly more stage III/IV patients in the low BMI group than in the other groups (P=0.001). Severe postoperative complications were more frequent (P=0.010) and the survival was worse (P<0.001) in the low BMI group. The subgroup analysis indicated that survival was worse in the low BMI group of the stage I/II subgroup (P=0.008). The severe postoperative complication rate was higher in the low BMI group of the stage III/IV subgroup (P=0.001), although the recurrence rate and survival did not differ in the stage III/IV subgroup among all the BMI groups. Low BMI was an independent poor prognostic factor in the stage I/II subgroup (disease-free survival: hazard ratio [HR], 13.521; 95% confidence interval [CI], 1.186-154.197; P=0.036 and overall survival: HR, 5.130; 95% CI, 1.644-16.010; P=0.005), whereas low BMI was an independent risk factor for severe postoperative complications in the stage III/IV subgroup (HR, 17.158; 95% CI, 1.383-212.940; P=0.027). Conclusions: Preoperative low BMI in patients with gastric cancer adversely affects survival among those with stage I/II disease and increases the severe postoperative complication rate among those with stage III/IV disease.

Counter-Rotating Type Pumping Unit (Impeller Speeds in Smart Control)

  • Kanemoto, Toshiaki;Komaki, Keiichi;Katayama, Masaaki;Fujimura, Makoto
    • International Journal of Fluid Machinery and Systems
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    • v.4 no.3
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    • pp.334-340
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    • 2011
  • Turbo-pumps have weak points, such as the pumping operation is unstable on the positive slope of the head curve and/or the cavitation occurs at the low suction head. To improve simultaneously both weak points, the first author invented the unique pumping unit composed of the tandem impellers and the peculiar motor with the double rotational armatures. The front and the rear impellers are driven by the inner and the outer armatures of the motor, respectively. Both impeller speeds are automatically and smartly adjusted in response to the pumping discharge, while the rotational torques between both impellers/armatures are counter-balanced. Such speeds contribute to suppress successfully not only the unstable operation at the low discharge but also the cavitation at the high discharge, as verified with the axial flow type pumping unit in the previous paper. Continuously, this paper investigates experimentally the effects of the tandem impeller profiles on the pump performances and the rotational speeds against the discharge, using the impellers whose loads are low and/or high at the normal discharge. The worthy remarks are that (a) the unstable operation is suppressed as expected and the shut off power is scarcely large in the smart control, (b) the blade profile contributes to determine the discharge giving the maximum/minimum rotational speed where the reverse flow may incipiently appears at the front impeller inlet, (c) the tandem impeller profiles scarcely affect the rotational speeds, while the loads of the front and the rear impellers are same, but (d) the impeller with the low load must run faster and the impeller with the high load must run slower at the same discharge to take the same rotational torque, and (e) the reverse flow at the inlet and the swirling velocity component at the outlet of the front impeller with the high load require making the rotational speed of the rear impeller with low load fairly faster at the lower discharge.

Nutritional Biochemistry of Selenium (셀레늄의 영양생화학)

  • Choi, Yong-Soon;Hesketh, John E.
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.5
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    • pp.661-670
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    • 2006
  • Selenium (Se) obtained from dietary sources including cereals, grains and vegetables is an essential micronutrient for normal function of the body. Plants convert Se into selenomethionine and incorporate it into proteins in place of methionine, while higher animals synthesize selenoproteins containing selenocysteine. Excessive Se in the body is methylated stepwise to methylated selenium metabolites from selenide. Both inorganic and organic forms of selenium can be the nutritional sources in human, and they are transformed to selenide and then the amino acid selenocysteine attached to a specific $tRNA^{ser(sec)}$. The selenocysteine (Sec) is incorporated into selenoprotein sequences by the UGA codon. The decoding of UGA as Sec requires specific mechanisms because UGA is normally read as a stop codon: cis-acting sequences in the mRNA (the selenocysteine insertion sequence, SECIS, within the 3'untranslated region) and trans -acting factors dedicated to Sec incorporation are required for incorporation of Sec during translation of selenoprotein mRNAs. Approximately 25 selenoproteins have been identified in mammals. Several of these, including glutathione peroxidases, thioredoxin reductases and selenoprotein P, have been purified or cloned, allowing further characterization of their biological function. The antioxidant properties of selenoproteins help prevent cellular damage from free radicals which may contribute to the development of chronic disease such as cancer and heart disease. Other selenoproteins have important roles in regulation of thyroid function and play a role in the immune system. Daily selenium iatake was reported to be $42.0{\pm}16.9{\mu}g/day$ in Korean adult women. This review focuses on the metabolism and biological functions of selenium, and the nutritional status of selenium in the Korean population.

The Effects of Dex and PDGF-BB on Bony Healing of Calvarial Defect in Rats (골재생 과정에서 혈소판유래성장인자-BB와 덱사메타존의 병용 효과)

  • Lee, Jae-Mok;Park, Jin-Woo;Suh, Jo-Young
    • Journal of Periodontal and Implant Science
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    • v.33 no.4
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    • pp.573-584
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    • 2003
  • Bone remodeling results from the combined process of bone resorption and new bone formation which is regulated in part by some of Dexamethasone related proliferation & mineralization of cultured bone cell and polypeptide growth factors such as platelet derived growth factor(PDGF), which has been known to be an important local regulator of bone cell activity and participate in normal bone remodeling. To evaluate the effects of Dex and PDGF on bony healing of calvarial defect in rats, 10 ng/ml PDGF were applied on P group and 10 ng/ml PDGF and $10^7$ M Dex were applied PD group. 4 rats in each group were sacrificed at 7, 14. 21 days after operation respectively, and the tissue blocks were prepared for light microscope with H-E for evaluation of overall healing, with TRAP(tartrate resistant acid phosphatase) for evaluation of osteoclastic activity and with immunohistochemical staining for macrophages. The results were as follows : 1. In all group, healing aspects were progressed from 7 days to 21 days in soft and bony tissue, but complete repair were not observed in bony defect 2. PDGF and control group were showed similar bony healing aspect , but bony healing in combination of PDGF-BB and Dex were observed slower aspect compared to PDGF and control group from early healing times. 3. There were no significant difference on activities of osteoclast and macrophages in bony healing between control and experimental group In conclusion, PDGF were not influenced on bony healing of defect and combination of PDGF-BB and Dex were showed slower healing through early healing times. it was considered that Dex compared to PDGF did influenced on early hone formation factors in healing period

The Effect of Five Different Trunk Stabilization Exercise on Thickness of Abdominal Muscle Using an Ultrasonography Imaging in Normal People (정상인에서 5가지 체간 안정화 운동자세가 초음파 영상을 이용한 복부근 두께에 미치는 영향)

  • Kang, Jung-Hyun;Shim, Jae-Hun;Chon, Seung-Chul
    • Physical Therapy Korea
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    • v.19 no.3
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    • pp.1-10
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    • 2012
  • The aim of this study is to compare measurements of abdominal muscle thickness using ultrasonography imaging (USI) to those using a special transducer head device, during five different trunk stabilization exercises, ultimately to determine which exercise led to the greatest muscle thickness. Thirty eight healthy subjects participated in this cross-sectional study. The five types of trunk stabilization - i.e., a sit-up on the supine, an upper and lower extremity raise with quadruped on the prone, a leg raise in sitting on the ball, trunk rolling on the ball, and balance using sling on the prone position - were each performed with an abdominal draw. The thickness of the abdominal muscle - including the transverse abdominal (TrA), internal oblique (IO), and external oblique (EO) - was measured by USI with a special transducer head device, at rest and then at contraction in each position. Data were analyzed using one-way repeated ANOVA with the level of significance set at ${\alpha}$=.05. The results were as follows: 1) the TrA thickness was statistically significant (p<.05), whereas the IO and EO thicknesses were not (p>.05); 2) among the five types of trunk stabilization, TrA thickness significantly increased with the balance using a sling in the prone position, (p<.05), whereas no significant difference was noted for the four types of trunk stabilization (p>.05); 3) reliability data showed that there was a high degree of consistency among the measurements taken using the special transducer head device (ICC=.92). In conclusion, the balance using a sling in the prone position was more effective than any of the four other types of trunk stabilization in increasing TrA thickness in healthy subjects.

Wave Deformation by Submerged Flexible Circular Disk (몰수된 원형 유연막에 의한 파랑변형)

  • 조일형;김무현
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.12 no.3
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    • pp.116-129
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    • 2000
  • The interaction of incident monochromatic waves with a tensioned, flexible, circular membrane submerged horizontally below free surface is investigated in the frame of three-dimensional linear hydro-elastic theory. The velocity potential is split into two parts i.e. the diffraction potential representing the scattering of incident waves by a rigid circular disk and the radiation potential describing motion induced waves by elastic responses of flexible membrane. The fluid domain is divided into three regions, and the diffraction and radiation potentials in each region are expressed by the Fourier Bessel series. The displacement of circular membrane is expanded with a set of natural functions, which satisfy the membrane equation of motion and boundary conditions. The unknown coefficients in each region are determined by applying the continuity of pressure and normal velocity at the matching boundaries. The results show that various types of wave focusing are possible by controlling the size, submergence depth, and tension of membrane.

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Sizing System for Medical Compression Stockings -Focus on Imported Medical Compression Stockings in the Korean Market- (의료용 압박스타킹의 사이즈 체계에 관한 연구 -한국 시장에서의 수입 의료용 압박스타킹을 중심으로-)

  • Do, Wol-Hee;Kim, Nam-Soon
    • Journal of the Korean Society of Clothing and Textiles
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    • v.36 no.8
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    • pp.860-874
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    • 2012
  • This study provides size information on current imported medical compression stockings in Korea. A total 20 brands from 6 countries imported and sold in the Korean on-off line markets were selected for this study and the sizing system of medical compression stockings was researched. The results of this study were as follows: there were size differences among different USA brands according to product type or compression class of medical compression stockings. To establish the sizing system for medical stockings of the German brands, the basic body measurements standard was set as cA, cY, cB, cB, cC, cD, cE, cF, cG, cH, cT, lD, lG, and lT. Italian brands developed the sizing system for medical compression stockings by compression class. In the Swiss brands, size types were sub-divided as 'Normal', 'Plus', 'Short', and 'Long'. The sizing 1 were confined within very narrow limits. There were differences of the basic body measurements between Taiwan brands. The results of the comparison of the size range of the imported brands with Size Korea (KATS, 2010) by two-way size distribution shows that the sizing systems of the imported brands were unsuitable for Koreans. To enhance the suitability of the sizing system for medical compression stockings, a new sizing system for Korean adult males and females needs to be established.

The Effects of Cryopreservation on Fine Structures of Pearl Oyster(Pinctada fucata martensii) Larvae (냉동보존이 진주조개(Pinctada fucata martensii) 유생의 미세구조에 미치는 영향)

  • Choi, Youn-Hee;Jo, Pil-Gue;Kim, Tae-Ik;Bai, Sung-Chul C.;Chang, Young-Jin
    • Development and Reproduction
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    • v.11 no.2
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    • pp.79-84
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    • 2007
  • The freezing susceptibilities of two larval stages (D-shaped and umbo) of the pearl oyster (Pinctada fucata martensii) were evaluated by the electron microscopy (light, transmission electron and scanning electron). The morphological shapes were examined from each pre-frozen or frozen-thawed stage of the cryopreserved larvae in liquid nitrogen by using the cryoprotectant, dimethyl sulfoxide ($Me_2SO$) mixed with sucrose. Although a portion of the shell was damaged, the hinge and prodissoconch were intact and clearly visible after preservation in liquid nitrogen. In addition, the cytoplasm of the frozen-thawed larvae maintained the normal organelle integrities, e.g., endoplasmic reticula, lipid droplets, mitochondria, nucleus and microvilli. However, some of the frozen-thawed larvae showed irregularly arranged cilia, rough shell surfaces and round-lumped cilium heads. These results indicate that P. fucata martensii larvae are susceptible to freezing, at least at those two critical developmental stages (D-shaped and umbo), and suggest a new industrial investigation including reduction method of cell injury for preserving microbial starter cultures need to be developed.

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