• Title/Summary/Keyword: E-normal

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Effect of combination treatment of vitamin E and insulin in streptozotocin-treated rats and BB rats II. Effect on the fatty acid composition of phospholipid (BB 랫드 및 streptozotocin이 투여된 랫드에서 vitamin E와 insulin 병합 투여 영향 II. 인지질의 지방산 조성에 미치는 영향)

  • Kim, Soon-tae;Huh, Rhin-sou
    • Korean Journal of Veterinary Research
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    • v.35 no.4
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    • pp.713-727
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    • 1995
  • The present study was investigated fatty acid composition of the phospholipid in the RBC membrane, liver and microsomal fraction after vitamin E and/or insulin treatment to evaluate the effect of vitamin E on the oxidative stress in STZ-treated rat and BB rat. Results obtained through the experiments were summarized as follows; 1. Effect of vitamin E and/or insulin treatment in STZ-treated rat 1) In the insulin treated group and the combination treated groups of vitamin E with insulin, body weights were increased compared to STZ-treated rat(STZ control group). Especially it was more significantly increased in the combination treated group of high dose vitamin E with insulin. 2) The composition of fatty acids of the phospholipid in RBC membrane, liver and microsomal fractions was shown a decreased C16:1, C18:1, C20:4 and an increased C16:0, C18:0, C18:2 in STZ control group compared to normal control group. In RBC membrane, liver and microsomal fractions after vitamin E with insulin treatment in STZ-treated rat, effect on the composition of fatty acids of the phospholipid was shown the result of a decreased C16:0, C18:0, C18:2 and an increased C16:1, C18:1, C20:4. 3) Hemolysis rate of the RBC to $H_2O_2$ was increased in the STZ control group and it was decreased below the hemolysis level of normal control group by vitamin E treatment. 2. Effect of vitamin E and/or insulin treatment in BB rat 4) Only in microsomal fraction, fatty acid composition was different between insulin treatment group and vitamin E with insulin treatment group. It was increased C16:0 and C18:1, and decreased C18:0 and C18:2 in vitamin E with insulin treatment group: But C20:4 was not different in two groups. These results suggest that the combination treatment of vitamin E and insulin could prevent the oxidative change of fatty acids in P-lipid of the RBC membrane, liver and microsomal fraction in STZ-treated rats and BB rats.

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한국 농촌지역의 임신효율 (Reproductive Efficiency)에 관한 연구 : 충남 서산지역을 중심으로

  • An, Mun-Yeong
    • Journal of agricultural medicine and community health
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    • v.7 no.1
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    • pp.74-79
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    • 1982
  • Recently in Korea, integration of F.P. & MCH programs for effective and efficient implementation of the health programs has been discussed actively. In fact, categorical health workers in fields have been trained and changed as an integrated health workers by government. But one of the most important problems that had to be solved for successful integration of F.P. and MCH programs, is that there must be a common indicator for the evaluation of the two health services (integrated indicator). We regarded reproductive efficiency (=R.E.) that had been proposed by Charlotter M$\ddot{u}$ller et al, as the good integrated indicator. The object of this brief article is to introduce the meaning of reproductive efficiency and to illustrate the usefulnesses of R.E. as the integrated health indicator by applying this indicator to the data from preliminary survey of Seosan demonstration project for integration of F.P. & MCH service supported by WHO. The results and conclusions are as follows 1) Definition of R.E. is the percentage of pregnancies that succeed in production normal, surving children after taking into account the frequency of all measurable types of adverse outcomes (End point for evaluation of survival is one year of age). 2) On the basis of the past pregnant history, reproductive efficiency of the 2,484 eligible women (15-44 years) was roughly 75% (But, in the concept of good births, it is not regarded whether the survived infant is normal health or not). 3) Compared with the results of the other two surveys of the rural area in Korea, reproductive efficiency has been slightly decreased than before, in spite of family planning and MCH services for past 20 years. Because the quantity of increased abortion rate overwhelmed that of the decreased infant mortality rate. 4) Reproductive efficiency has the object for measure many events during the period from the conception (Wanted pregnancy) to an normal surviving children as an 1 year of age. So these heterogenous adversities, ie, induced abortion, still births, spontaneous abortion, neonate & infant death, are aggregated as R.E. However, if the information of these important events and reproductive efficiency were given, R.E. is used as the comprehensive evaluation indicator for F.P. and M.C.H. after meticulous analysis the various components of R.E. 5) Economic loss for adverse outcomes of preg were pregnancy were calculated applying the medical cost at the relatively small sized hospital of small city. Economic loss for 100 cases of adverse outcome is 10,420,000 won, and economic loss for infant death is 46.1% of the total loss. So, it is rational to invest much more effort and than before to MCH programs.

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A STUDY ON OCCLUSAL PATTERNS OF HANDICAPPED PERSONS (심신장애자의 교합양상에 관한 연구)

  • Kim, Nam Soo;Lee, Dong Joo
    • The korean journal of orthodontics
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    • v.13 no.1
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    • pp.31-43
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    • 1983
  • The following results were abtained based on the research of the occlusal patterns among 1074 handicapped persons (cerebral palsy: 46, mental subnormality: 619, deafmute: 285, blind: 111, childish autism:8, cleft lip and cleft palate:3, polimyelitis:2) of the age between 6 and 23 in Chollanamdo, Korea, in comparison with a normal group of 1048 children of the age between 6 and 15 selected at random in J primary school in Gwang-ju City. 1. According to Angle's malocclusion classification, all the handicapped groups, except the cerebral palsy and the blind, showed a higher prevalence of malocclusion than that of the normal. Especially the prevalence of Class II, devision 1 malocclusion in the cerebral palsy was the highest, and the prevalence of Class III malocclusion in all the handicapped groups was higher than that of the normal group. Among these groups the highest prevalence of Class III malocclusion was in the Down's syndrome group. 2. On the the abnormal pattern of the anterior region, there was no significant difference $(P\leqq0.05)$ between the normal and the cerebral palsy, the deafmute, and e blind. The open bite $(7.27{\pm}1.04\%)$ and the cross-bite $(32.7{\pm}6.33\%)$ of the Down's syndrome wire higher than that of the normal, and the forward position of the mandible could be recognized in the Down's syndrome group. 3. On the midline position of the dentition, all the handicapped showed the same percentage of deviation, but the degree of mandibular shift to the right $(20.00{\pm}5.39\%)$ or left $(10.91{\pm}4.20\%)$ was higher than that of the normal only in the Down's syndrome group. 4. On the abnormal pattern of the posterior region, the cross-bite of the Down's syndrome was higher than that of the normal by $20.00{\pm}5.39\%$, the cross-bite of the cerebral palsy and the cross-bite and the open bite of the mental subnormality were slightly higher than that of the normal. The other handicapped groups showed no significant difference $(P\leq0.05)$ to the normal.

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Facilitation of AMPA receptor-mediated steady-state current by extrasynaptic NMDA receptors in supraoptic magnocellular neurosecretory cells

  • Pai, Yoon Hyoung;Lim, Chae Seong;Park, Kyung-Ah;Cho, Hyun Sil;Lee, Gyu-Seung;Shin, Yong Sup;Kim, Hyun-Woo;Jeon, Byeong Hwa;Yoon, Seok Hwa;Park, Jin Bong
    • The Korean Journal of Physiology and Pharmacology
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    • v.20 no.4
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    • pp.425-432
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    • 2016
  • In addition to classical synaptic transmission, information is transmitted between cells via the activation of extrasynaptic receptors that generate persistent tonic current in the brain. While growing evidence supports the presence of tonic NMDA current ($I_{NMDA}$) generated by extrasynaptic NMDA receptors (eNMDARs), the functional significance of tonic $I_{NMDA}$ in various brain regions remains poorly understood. Here, we demonstrate that activation of eNMDARs that generate INMDA facilitates the ${\alpha}$-amino-3-hydroxy-5-methylisoxazole-4-proprionate receptor (AMPAR)-mediated steady-state current in supraoptic nucleus (SON) magnocellular neurosecretory cells (MNCs). In $low-Mg^{2+}$ artificial cerebrospinal fluid (aCSF), glutamate induced an inward shift in $I_{holding}$ ($I_{GLU}$) at a holding potential ($V_{holding}$) of -70 mV which was partly blocked by an AMPAR antagonist, NBQX. NBQX-sensitive $I_{GLU}$ was observed even in normal aCSF at $V_{holding}$ of -40 mV or -20 mV. $I_{GLU}$ was completely abolished by pretreatment with an NMDAR blocker, AP5, under all tested conditions. AMPA induced a reproducible inward shift in $I_{holding}$ ($I_{AMPA}$) in SON MNCs. Pretreatment with AP5 attenuated $I_{AMPA}$ amplitudes to ~60% of the control levels in $low-Mg^{2+}$ aCSF, but not in normal aCSF at $V_{holding}$ of -70 mV. $I_{AMPA}$ attenuation by AP5 was also prominent in normal aCSF at depolarized holding potentials. Memantine, an eNMDAR blocker, mimicked the AP5-induced $I_{AMPA}$ attenuation in SON MNCs. Finally, chronic dehydration did not affect $I_{AMPA}$ attenuation by AP5 in the neurons. These results suggest that tonic $I_{NMDA}$, mediated by eNMDAR, facilitates AMPAR function, changing the postsynaptic response to its agonists in normal and osmotically challenged SON MNCs.

The competing roles of extensional viscosity and normal stress differences in complex flows of elastic liquids

  • Walters, K.;Tamaddon-Jahromi, H.R.;Webster, M.F.;Tome, M.F.;McKee, S.
    • Korea-Australia Rheology Journal
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    • v.21 no.4
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    • pp.225-233
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    • 2009
  • In various attempts to relate the behaviour of highly-elastic liquids in complex flows to their rheometrical behaviour, obvious candidates for study have been the variation of shear viscosity with shear rate, the two normal stress differences $N_1$ and $N_2$, especially $N_1$, and the extensional viscosity $\eta_E$. In this paper, we shall be mainly interested in 'constant-viscosity' Boger fluids, and, accordingly, we shall limit attention to $N_1$ and $\eta_E$. We shall concentrate on two important flows - axisymmetric contraction flow and "splashing" (particularly that which arises when a liquid drop falls onto the tree surface of the same liquid). Modern numerical techniques are employed to provide the theoretical predictions. It is shown that the two obvious manifestations of viscoelastic rheometrical behaviour can sometimes be opposing influences in determining flow characteristics. Specifically, in an axisymmetric contraction flow, high $\eta_E$ can retard the flow, whereas high $N_1$ can have the opposite effect. In the splashing experiment, high $\eta_E$ can certainly reduce the height of the so-called Worthington jet, thus confirming some early suggestions, but, again, other rheometrical influences can also have a role to play and the overall picture may not be as clear as it was once envisaged.

ON GENERALIZED SPHERICAL SURFACES IN EUCLIDEAN SPACES

  • Bayram, Bengu;Arslan, Kadri;Bulca, Betul
    • Honam Mathematical Journal
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    • v.39 no.3
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    • pp.363-377
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    • 2017
  • In the present study we consider the generalized rotational surfaces in Euclidean spaces. Firstly, we consider generalized spherical curves in Euclidean (n + 1)-space ${\mathbb{E}}^{n+1}$. Further, we introduce some kind of generalized spherical surfaces in Euclidean spaces ${\mathbb{E}}^3$ and ${\mathbb{E}}^4$ respectively. We have shown that the generalized spherical surfaces of first kind in ${\mathbb{E}}^4$ are known as rotational surfaces, and the second kind generalized spherical surfaces are known as meridian surfaces in ${\mathbb{E}}^4$. We have also calculated the Gaussian, normal and mean curvatures of these kind of surfaces. Finally, we give some examples.

Aligning Method using Concentric $Moir\'{e}$ in Nanoimprint Lithography (나노 임프린트 리소그라피에서 동심원 모아레를 이용한 정렬방법)

  • Kim, Gee-Hong;Lee, Jae-Jong;Choi, Kee-Bong;Park, Soo-Yeon;Cho, Hyun-Taek;Lee, Jong-Hyun
    • Journal of the Korean Society for Precision Engineering
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    • v.23 no.11 s.188
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    • pp.34-41
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    • 2006
  • Nanoimprint lithography is an emerging technology which has an ability to make patterns under 100nm width. Recently many researches have been focused to develop multilayer patterning function in nanoimprint lithography and aligning method is attracting attention as a key technology. $Moir\'{e}$ has been used widely to measure dislocation or deformation of objects and considered one of the best solutions to detect aligning error in nanoimprint lithography. Concentric circular patterns are used to generate a $moir\'{e}$ fringe in this paper and aligning offset and direction are extracted from it. Especially this paper shows the difference of fringe equation of $moir\'{e}$ which can be obtained in nanoimprint process atmosphere from normal one.

A Study on the impact factors that affect the effectiveness of education in SCORM based e-learning (SCORM 기반 이러닝 교육효과에 영향을 미치는 요인에 관한 연구)

  • Lim, Gyoo-Gun;Yang, Woo-Jin
    • Proceedings of the Korea Database Society Conference
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    • 2008.05a
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    • pp.163-182
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    • 2008
  • In this study, the survey from nationwide universities, e-learning service companies, and students who take e-learning courses was proof-analyzed. Sufficiency, variety, usability, accessability, and interaction with instructors were the criteria for analyzing the effectiveness of e-learning education. For this, the factors about effectiveness of e-learning education between the SCORM contents users group and normal contents users group were compared and analyzed. The differences between those two groups were appeared.

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AN ELECTROMYOGRAPHIC STUDY OF MUSCLE ACTIVITY IN NORMAL OCCLUSION AND SKELETAL CLASS III MALOCCLUSION IN ADULT (성인에서 골격형 III급 부정교합자와 정상교합자의 근활성도에 관한 연구)

  • Kim, Taik-Soo;Sohn, Byung-Hwa
    • The korean journal of orthodontics
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    • v.22 no.3 s.38
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    • pp.627-646
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    • 1992
  • The purpose of this study was to investigate the relationship among the activity of the craniofacial muscle and craniofacial form and occlusal state. In this study, subjects were consisted of 23 male adults with skeletal Class III malocclusion and 30 male adults with normal occlusion. The measurements in oral exam, lateral ceghalogram, and E.M.G. recordings of anterior temporal, masseter, and upper lip muscles at rest position, clenching in centric occlusion, chewing of gum, swallowing of juice, were analyzed with SPSS system. The results were as follows: 1. At rest position upper lip muscle activity of skeletal Class III group was significantly higher than that of normal group. 2. Both clenching and chewing masseter and temporal muscle activity of normal group were significantly higher than that of skeletal Class III group. 3. During swallowing of juice, upper lip muscle activity of skeletal Class III group were significantly higher than that of normal group. 4. The activities of masseter and anterior temporal muscle during clenching and chewing were significantly correlated with hypodivergent facial form and number of occluded teeth. 5. The activity of upper lip during swallowing had positive correlation with mandibular prognathism.

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Differentiation between Normal and White Striped Turkey Breasts by Visible/Near Infrared Spectroscopy and Multivariate Data Analysis

  • Zaid, Amal;Abu-Khalaf, Nawaf;Mudalal, Samer;Petracci, Massimiliano
    • Food Science of Animal Resources
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    • v.40 no.1
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    • pp.96-105
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    • 2020
  • The appearance of white striations over breast meat is an emerging and growing problem. The main purpose of this study was to employ the reflectance of visible-near infrared (VIS/NIR) spectroscopy to differentiate between normal and white striped turkey breasts. Accordingly, 34 turkey breast fillets were selected representing a different level of white striping (WS) defects (normal, moderate and severe). The findings of VIS/NIR were analyzed by principal component (PC1) analysis (PCA). It was found that the first PC1 for VIS, NIR and VIS/NIR region explained 98%, 97%, and 96% of the total variation, respectively. PCA showed high performance to differentiate normal meat from abnormal meat (moderate and severe WS). In conclusion, the results of this research showed that VIS/NIR spectroscopy was satisfactory to differentiate normal from severe WS turkey fillets by using several quality traits.