• Progress in Medical Physics
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• v.9 no.4
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• pp.259-266
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• 1998

To achieve the 2D dose distribution around the designed high dose rate Ir-192 source substitution for Co-60 brachytherapy source, we determined the exposure rate constant and tissue attenuation factors as a large depth as a 20 cm from source center. The exposure rate constant is used for apparent activity in designed source with self-absorption and encapsulation steel wall. The tissue dose delivered from the 4401 segments of 2.5 mm in a diameter and 2.5 mm height of disk-type source layer. In the experiments, the tissue attenuation factors include the tissue attenuation and multiple scattering in a medium surrounding the source. The fitted the polynomial regression with 4th order for the tissue attenuation factors are very closed to the experimental measurement data within ${\pm}$1% discrepancy. The Meisberger's constant showed the large uncertainty in large distance from source. The exposure rate constant 4.69 Rcm$^2$/mCi-hr was currently used for determination of apparent activity of source and air kerma strength was obtained 0.973 for tissue absorbed dose from the energy spectrum of Ir-192 source. In our experiments with designed high dose rate brachytherapy source, the apparent activity of Ir-192 source was delivered from the 54.6 % of actual physical source activity through the self-absorption and encapsulation wall attenuations. This paper provides the 2-dimensional dose tabulation from unit apparent activity in a water medium for dose planning includes the multiple scattering, source anisotropy effect and geometric factors.

• Journal of Korean Society of Forest Science
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• v.88 no.2
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• pp.240-248
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• 1999

On the basis of data obtained from five forest roads collapsed due to a heavy rainfall of 1995 in Chunchon, Kangwon-do, this study was carried out to evaluate and predict the fill slope failure of forest roads with four factors of forest road structure and those of location condition by using Quantification theory(II). The results were summarized as follows ; In the structure factors of forest road, the fill slope failure was mainly occurred in longitudinal gradients less than $2^{\circ}$ or more than $4^{\circ}$, distance of surface-flow longer than 80m, fill slope length greater than 6m, and fill slope gradients steeper than $35^{\circ}$. In the factors of location condition, the failure was mainly occurred in ridge portion of road position, weathered rock and soft rock of constituent material, slope gradients in the range from $35^{\circ}$ to $45^{\circ}$, and concave and convex of longitudinal slope forms. The priority order for factors influencing on fill slope failure was ranked by fill slope length, constituent material, road position, and so on. And the rate of correct discrimination by analysis of fill slope failure was estimated at the high prediction of 86.5%.

• Journal of Korean Society of Forest Science
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• v.96 no.6
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• pp.667-675
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• 2007

The genetic diversity and the spatial structure in two populations of Abelia tyaihyoni in Yeongwol region were studied by employing I-SSR markers. In spite of the limited distribution and small population sizes of Abelia tyaihyoni, the amount of genetic diversity estimated at the individual level was comparable to other shrub species (S.I.=0.336, h=0.217). Genetic diversity at the genet level was very similar to that at individual level. (S.l.=0.339, h=0.219). About 18.7 percent of total variation was allocated between two populations, which was slightly higher or similar level as compared with other shrub species. Genotypic diversity estimated by the ratio of the number of genets ($N_G$) over the total number of individuals (N) and a modified Simpson's index ($D_G$) were also higher than those of other shrubs. The maximum diameter of a genet did not exceed 5.5 m. The high level of gene and genotypic diversity, and the relatively limited maximum diameter of a genet suggested that the clonal propagation is not the most dominant factor in determining the population structure of Abelia tyaihyoni. Spatial autocorrelation analysis revealed significant spatial genetic structure within 12 m and 18 m distances in two populations A and B, respectively. Autocorrelations among individuals at the both individual and genet levels in each population didn't show any considerable differences. As a sampling strategy for ex-situ conservation of populations showing continuous distribution, a minimum distance of 18 m between individuals was recommended. For the populations with many segments, it was considered very crucial to sample materials from as many segments as possible.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.1061-1065
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• 2013

Objective: To investigate the treatment effect of additional information obtained by single photon emission computed tomography (SPECT) lung perfusion imaging (LPI) in the radiotherapy planning process for patients with stage III non-small cell lung cancer (NSCLC). Methods: 39 patients with stage III NSCLC were enrolled. Gross tumor volume (GTV) was outlined by SPECT/CT images, SPECT-LPIs being used to define functional lung (FL) and non-functional lung (NFL) regions. Two sets of IMRT plans were designed to deliver 64Gy to PTV. One was a regular IMRT plan using CT images only (Plan 1), and the other was a corresponding IMRT plan using co-registered images (Plan 2). $FL_{Vx}$ (the % volume of functional lung receiving ${\geq}$x Gy) and $WL_{Vx}$ (% volume of whole lung to receive ${\geq}$x Gy) were compared by paired Student's t test. Kendalls correlation was used to analyze the factor (s) related with the FLV20 decrease. Results: Compared with plan 1, both $WL_{Vx}$ and $FL_{Vx}$ were decreased in plan 2. $WL_{V10}$, $WL_{V15}$, $WL_{V20}$, $WL_{V25}$, $WL_{V30}$ and $WL_{V35}$ decreased 9.7%, 13.8%, 17.2%, 12.9%, 9.8% and 9.8%, and $FL_{V10}$, $FL_{V15}$, $FL_{V20}$, $FL_{V25}$, $FL_{V30}$ and $FL_{V35}$ decreased 10.8%, 14.6%, 17.3%, 14.5%, 14.5% and 10.5%. $FL_{Vx}$ decreased significantly compared with $WL_{Vx}$. There were significant differences in $WL_{V10}$, $WL_{V15}$, $WL_{V20}$, $WL_{V25}$, $WL_{V3}$ and $FL_{V10}$, $FL_{V15}$, $FL_{V20}$, $FL_{V25}$, $FL_{V30}$ between plan 1 and plan 2 (P=0.002, 0.000, 0.000, 0.005, 0.027 and 0.002, 0.000, 0.000, 0.006, 0.010). According to Kendall correlation analysis, NFL had a negative relation with the percentage FLV20 decrease (r=-0.559, P<0.01), while the distance of PTV and NFL center had a significantly positive relation with the percentage of FLV20 decrease (r=0.768, P<0.01). Conclusion: Routine use of SPECT-LPI for patients undergoing radiotherapy planning for stage III NSCLC appears warranted.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.31 no.2
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• pp.128-135
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• 2013

The purpose of this study is a suggestion that it is a way for conservation and management the Namgye Seowon's heritage value based on its landscape visibility and land use; Namgye Seowon is a world heritage registration object. To do this, We had done a field investigation and a literature examination. The investigations are as following; first, setting protection zone through a comprehensive approach beyond uniform cultural properties protection zone is to note current intellectual situations as well as the place related to the locational characteristics and figures of Namgye Seowon. It's to set fore seeable section of landscape by analyzing visibility focusing through on Pungyeongnu, and it consider with protection zone and the present condition of land use. Especially, external view of landscape in Namgye Seowon is visualized with Baekam-san in the distance view of it and Cheonhwang-bong in Daebong-san and nearby large soundproof walls and the towers acts as an impediment factor to the view of landscape. In addition, to recover the original view of landscape of the Namgye Seowon, reckless plans focusing the authenticity of the world heritage should be limited and in case of the vegetation landscape, restoration and maintenance will be made through historical research literature. Through this study, researches on Namgye Seowon and several seowons will be done actively and its aims are to become the framework of landscape conservation and management measures to meet world heritage criteria.

• Journal of Korean Ophthalmic Optics Society
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• v.7 no.1
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• pp.9-13
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• 2002

It is well known that the maximum amplitude of accommodation decreases with increasing age.(Presbyopia). With single vision lenses presbyopia can be corrected only for one viewing distance. With progressive power lenses presbyopia can be corrected for all viewing distances. But there are some other changes in the visual system with age which can not be corrected by spectacle lenses. Pupillary diameter decreases and the light transmission of the ocular media decreases. Therefore old people need more light, they need better illumination. Cone density in the retina decreases, this is only one example for changes in the sensory system. These changes in the visual system cause changes in visual functions. At the age of 80 visual acuity has decreased to half. Contrast sensitivity for gratings decreases mainly for high spatial frequencies very important is the increase of stray light in the ocular media and therefore the increase of glare. Veiling luminance increases by a multiple of approximately 4, Dark adaptation gets slower and light sensitivity is approximately 2 log units (factor 100) less when the eye is completely dark adapted. Also colour vision gets worse, especially at low luminances. Elderly people have problems with visual tasks which require divided attention between foveal and peripheral vision. An example is the measurement of the useful field of view. This useful field of view be expanded (improved) by visual training.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.23 no.5
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• pp.383-392
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• 2011

The basic research of the estuarine circulation at Gyeong-Gi bay has not been well studied up to now, although coastal development pressures have been continuously increased. To understand the oceanographic phenomena at the Han River estuary, it's essential to understand the propagation characteristic of tidal wave which is the strongest external forcing in this region. In this study, we investigate the tidal wave propagation characteristics along the 3 major channels using observation data and numerical model. It is found that 3 channels are all hyper-synchronous and the most important physical factor controlling the tidal wave propagation is topographical convergence of estuary shape and friction. The result of analytic solution at ideal channel considering the topographical convergence and friction show that the contribution of physical role of convergence and friction varies at 3 different channel. And the ratio of convergence and friction at Yeomha channel is four times larger than Seokmo channel. Because of this effect, the location of maximum amplitude at Yeomha channel is showed up downward than Seokmo channel. The ratio of decreasing amplitude and increasing phase per unit distance between stations is bigger than Seokmo channel. Although 3 major channel show a hyper-synchronous pattern, Yeomha shows more frictionally dominant channel and Seokmo channel is more dominantly affected by convergence effect.

• Economic and Environmental Geology
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• v.43 no.2
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• pp.149-162
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• 2010

The most serious problem in oil stockpiles with artificial underground cavern is maintaining the stability of ground water system. In order to understand the ground water system around K-1 site, we determined the regional flow direction and level distribution of groundwater, and investigated the major geologic factors influencing their flow system. Reactivated surface along the contact between granite and gneiss, and fractures and faults along the long acidic dyke may contribute as important pathways for groundwater flow. Within K-1 site, groundwater level fluctuation is closely related to the rainfall events and injection from surface or influx water. In this project, the effect of groundwater pumping from the southern wells was examined. Based on equations relating water level drawdown to pumping rate at those wells, their pumped outflow of groundwater ranged from $80\;m^3$/day to less than $250\;m^3$/day. The modeling results with MODFLOW imply that the previous groundwater pumping at distance of 1.2 km may not affect the groundwater level variations of the K-1 site. However, continuous pumping work at quantity over $250\;m^3$/day in this area will be able to affect the groundwater system of the K-1 site, particularly along the acidic dyke.

• Journal of Oriental Neuropsychiatry
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• v.19 no.2
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• pp.77-93
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• 2008

Objective : This experiment was designed to investigate the effect of the CBD hot water extract & ultra-fine Powder on Alzheimer's Disease Model Induced by ${\beta}A$. Method : The effects of the CBD hot water extract on expression of interleukin-1 beta($IL-1{\beta}$), $TNF-{\alpha}$ mRNA and production of IL-6, $TNF-{\alpha}$ in BV2 microglial cell line treated by lipopolysacchaide(LPS). The effects of the CBD hot water extract & ultra-fine powder on (1) the behavior (2) expression of $IL-1{\beta}$, tumor necrosis factor-alpha($TNF-{\alpha}$), (3) the infarction area of the hippocampus in Alzheimer's diseased mice induced with ${\beta}A$ were investigated. Result : The CBD hot water extract suppressed the expression of $IL-1{\beta}$, $TNF-{\alpha}$ mRNA in BV2 microglia cell line treated with LPS. The CBD hot water extract significantly suppressed the production of $IL-1{\beta}$, $TNF-{\alpha}$ in BV2 microglial cell line treated with LPS. The CBD hot water extract & ultra-fine powder a significant inhibitory effect on the memory deficit was shown for the mice with Alzheimer's disease induced by ${\beta}A$ in the Morris water maze experiment, which measured step-through latency and distance movement-through latency. The CBD hot water extract & ultra-fine powder significantly suppressed the expression of $IL-l{\beta}$ and $TNF-{\alpha}$ protein in the microglial cell of mice with Alzheimer's disease induced by ${\beta}A$. The CBD hot water extract & ultra-fine powder suppressed the over-expression of AChE activity in the serum of the mice with Alzheimer's disease induced by ${\beta}A$. The CBD hot water extract & ultra-fine powder reduced infarction area of hippocampus, in the mice with Alzheimer's disease induced by ${\beta}A$. Conclusions : These results suggest that the CBD hot water extract & ultra-fine powder may be effective for the prevention and treatment of Alzheimer's disease. Investigation into the clinical use of the CBD hot water extract & ultra-fine powder for Alzheimer's disease is suggested for future research.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.10A
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• pp.1014-1019
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• 2006

The research deals with the measurement of electromagnetic wave propagation in subway tunnels at 2.65GHz. Measurements have been conducted in 4 different types of tunnel courses, a straight tunnel, two curved tunnels, with 245m and 500m radius of curvature, and a tunnel that has both straight and curved sections. we found that the path loss exponent for the line-of-sight(LOS) region inside all the tunnels is $1.31{\sim}2.19$. The path loss exponents for LOS regions in the tunnel is lower than $(3{\sim}4)$, which corresponds to the path loss exponent factor for outdoor cellular environments. The path loss exponents of the straight tunnel, two curved tunnels with 245m and 500m radius of curvature are 1.94, 2.92, and 4.34, respectively. This indicates that a smaller radius of curvature in tunnel results in a higher path loss exponent for nonline-of-sight(NLOS) region. The path loss exponents for the NLOS region in the combined and curved tunnel, which have the same radii of cuvature, are 5.88 and 4.34, respectively. Therefore, it can be concluded that the path loss characteristics in tunnel environments are infulenced by the radii of curvature as well as the LOS distance.