• Environmental Mutagens and Carcinogens
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• v.26 no.1
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• pp.1-6
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• 2006

To enhance our understanding of toxicity mediated through the pathway by which TCDD stimulates gene expression, we have investigated genes whose expressions are changed after treatment with TCDD and/or MNNG in human Chang liver cell. First, we treated with MNNG and TCDD for two weeks to transform human Chang liver cell. We obtained cell looks like to be transformed and compared the differential gene expression by using cDNA chip (Macrogen) which carrys genes related with signal transduction pathways, oncogenes and tumor suppressor genes, etc. We found that TCDD up- or down-regulated 203 and 111 genes including oncogenes and tumor suppressor genes in human Chang liver cell two fold or more, respectively. Second, we compared the differential gene expression after treatment with TCDD only by using cDNA chip (Superarray) which carrys genes related with cell cycle regulations, and found that TCDD up regulated genes related with cell proliferation as well as cell growth inhibition in human Chang liver cell two fold or more, respectively. These results suggest that toxicity induced by TCDD may reflect sustained alterations in the expression of many genes and that the changes reflect both direct and indirect effects of TCDD.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.36 no.3
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• pp.186-194
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• 2000

bottom as a reference basis, some theoretical elements which form bottom echoes during acoustic survey of demersal fish were considered. A stable bottom detection method based on maximum voltage difference, which was not influenced by variable levels and waveform transformation. The method has been shown to be effective using in-situ bottom echo waveforms and computer simulation data. A comparison between near-bottom SV profiles acquired in Funka Bay, Hokkaido, of Japan, the East China Sea and the Yellow Sea, of Korea, with the threshold method and maximum differential voltage method, shows that the SV obtained with the maximum differential voltage method is 4-6 dB higher than those with threshold method within 2m from the bottom.

• Korean Journal of Materials Research
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• v.26 no.5
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• pp.235-240
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• 2016

Appropriate thermo-mechanical properties of nickel-based superalloys are achieved by heat treatment, which induces precipitation and solid solution hardening; thus, information on the temperature ranges of precipitation and dissolution of the precipitates is essential for the determination of the heat treatment condition. In this study, thermal analyses of nickel-based superalloys were performed by differential scanning calorimetry method under conditions of various heating rates of 5, 10, 20, or 40K/min in a temperature range of 298~1573K. Precipitation and dissolution temperatures were determined by measuring peak temperatures, constructing trend lines, and extrapolating those lines to the zero heating rate to find the exact temperature under isothermal condition. Determined temperatures for the precipitation reactions were 813, 952, and 1062K. Determined onset, peak, and offset temperatures of the first dissolution reaction were 1302, 1388, and 1406K, respectively, and those values of the second dissolution reaction were 1405, 1414, and 1462K. Determined solvus temperature was 1462K. The study showed that it was possible to use a simple method to obtain accurate phase transition temperatures under isothermal condition.

• Journal of architectural history
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• v.7 no.4 s.17
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• pp.131-150
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• 1998

Main theme of this study is the acceptance phase of western architectural culture in modern east-north asia through a series of actual survey and typological analysis of existing church buildings in modern Korea. China. Japan. For this study, 126 modern church buildings of Korea, China, Japan are selected. Also, main subject of this study has deal with the side of culture - thought which background of christianity acceptance and acceptance mind of acceptance main-body, culture adaptation and transformation based on characteristic culturalization of Korea, China, Japan. Especially, I would consistently tried to see the acceptance phase of western architectural culture according to differential acceptance mind of acceptance main-body based on characteristic culturalization of three countries. Conclusively, in the point of view of western architectural culture acceptance phase, it could be said that Korean church architecture had characterized as a blending phase of the two eclectic architectural culture. And in the case of china, as a coexistance phase of the two architectural culture with more western style-oriented. On the other hand, Japanese church architecture had characterized as a syncretism phase of the both traditional and western architectural culture, though it is eclectic style-oriented. Therefore, it is thought that different acceptance mind of western culture had main factors caused of differential acceptance phase, when the two architectural culture, the traditional and the western, encounters.

• Journal of Advanced Marine Engineering and Technology
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• v.27 no.2
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• pp.272-279
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• 2003

This study aimed to understand the effects of transporting ice slurry Particles through Pipes with branches. The experimental apparatus was constructed as ice slurry mixing tank. vortex pump, manometers for differential pressure measuring. IPF(ice packing factor) measuring instruments and branches as test sections. The experiments were carried out under various conditions. with concentration of water solution ranging between 0∼20wt% and velocity of water solution at the entry ranging between 1.5∼2.5m/s. The differential Pressure and IPF between the pipe entry and exit were measured. and flowing form was checked throughout the experiment. The pressure loss in 3d branches appeared compared with 6d branches so that it was very high. In the pressure loss of the inside and outside of branches. 6d branches was showed the difference. but was agreed in 3d branches The pressure loss according to concentration of water solution, low value appeared at 10wt% in 6d branches, at 20wt% in 3d branches. The pressure loss according to velocity, did not show large difference. The change of IPF at outlet, appeared +15∼-25% in 6d branches and 0∼-20% in 3d branches. The difference of IPF at the inside and outside of branches. appeared 10∼15% in 6d branches and maximum 5% in 3d branches.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.13
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• pp.5489-5492
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• 2015

Background: Gradual loss of cytokeratin 13 (CK13) may be linked with the severity of dysplastic changes and transformation to malignancy. In this study we assessed the differential expression of CK13 in normal, hyperplastic, dysplastic and cancerous oral mucosa. Materials and Methods: A total of 93 oral biopsies were collected during the 2011-2014 period. The biopsies were characterized as normal (19), hyperplastic (21), severely dysplastic/carcinoma in situ (16) and invasive oral squamous cell carcinoma (OSCC) (37) after morphological assessment. Formalin fixed paraffin embedded sections were stained with a monoclonal antibody against CK13 using the Envision technique. Immunohistochemically stained slides were then analyzed for CK13 expression. Results: CK13 was consistently and diffusely expressed in all normal and hyperplastic tissue biopsies from oral mucosa. Severely dysplastic/carcinoma in situ biopsies showed complete loss in 50% of cases, while in the remaining 50% expression was very focal and weak. OSCC cases showed complete or near complete loss of CK13 in all cases. Few cases showed weak expression in keratin pearls only. Conclusions: This study validates the utility of CK13 IHC as a useful immunohistochemical marker in routine diagnostic practice to make distinction between non-neoplastic from dysplastic and neoplastic (malignant) oral lesions.

• The KIPS Transactions:PartC
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• v.9C no.4
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• pp.445-452
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• 2002

In this paper, we suggest the design of 128bit block cipher which is provable security based on mathematics theory. We have derived the 16$\times$16 matrix(i.e.,linear transformation) which is numerous active S-box, and we proved for DC and LC which prove method about security of SPN structure cipher algorithm. Also, the minimum number of active S-box, the maximum differential probabilities and the maximum linear probabilities in round function of 128bit block cipher algorithm which has an effect to DC and LC are derived.

• Journal of the Korean Society of Food Culture
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• v.20 no.3
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• pp.299-304
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• 2005

This study investigated the feasibility of the bread making process with the mixture of the functional rice flour. The bread was manufactured with 20, 30 or 40% functional rice flour with increasing and wheat flour. Gelatinization characteristics of the rice starch was examined by differential scanning calorimetry(DSC). Coated with soluble dietary fiber rice showed the highest gelatinization enthalphy among functional rices and other functional rices were similar to normal rice. in the viscosity point of view. generally the viscosity related to the addition ratio. The most viscose case was 30% Sangwhang rice but in fermented with monascus ruber rice case, viscosity was low even with 40% case because of the transformation of the starch granules. In sensory evaluation, the highest sensory scores for the uniformity of pore size and flavor were obtained when sangwhang rice flour content was 20%. The textual study was mainly focused on the hardness, cohesiveness, adhesiveness, springiness, chewiness. Textural characteristics of functional rice bread crumb bakedwith 20% coated with soluble dietary fiber rice, 20% sangwhang was low in hardness, chewiness and gumminess. Therefore, Sangwhang rice flour 20%, Monascous ruber 20% and Coated soluble dietary fiber rice 20% were considered to be the most suitable addition ratio for the rice breads.

• Journal of the Korean Home Economics Association
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• v.35 no.4
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• pp.159-172
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• 1997

The purpose of this study was to investigate the slacks pattern making on the movement -fitness of the hip region. The experimental items were divided into the 5 lower limb movements(M1-M5) and the 12 revision pattern constructions of slacks. This study was done by clothing pressure test sensory evaluation test and the difference shape-transformation of wearing-slacks. The summarized finding resulted from experiments and investigation are suggested as follows: First by the clothing pressure tested by lower limb movements the clothing pressure score of the rabbit leap movement(M3) was the highest of all lower limb movements and the order of it in the another movement was the sit on knee(M4) the sit on chair(M2) the noble sitting(M5) from the highest to the lowest. And in comparision of clothing pressure tested by revision pattern to cover the extend of crotch-length 20。 inclined back-line construction method (CA4) showed the lowest. And in comparision of clothing pressure tested by revision pattern to cover the extend of crotch-length 20。 inclined back-line construction method (CA4) showed the lowest. And also for a role to cover hip circumference extendign CC4(1/5 hip.1cm longrightarrow linked back -line) method showed the lowest. Second by the sensory evaluation test based on the movement and revision patterns it was found that the functional factor score of the rabbit leap movement was the lowest in all movement however the score of revision patterns were higher than basic pattern. Third by the test to show difference in the shape-transformation of wearing-slacks on chair(M2) also need to be analyzed. The ration of the shape-transformation of the knee region showed the least value in the increased patterns of inclined angle of back-line(CA) and the differential methods of back-line inclined pattern making. But that of the hem-line did not show remarkable difference.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.18 no.4
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• pp.308-320
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• 2006

An analytic solution to the mild-slope equation is derived for waves propagating over an axi-symmetric pit. The water depth inside the pit varies in proportion to a power of radial distance from the pit center. The governing equation is transformed into ordinary differential equations by using separation of variables, and the coefficients of the equations are transformed into explicit forms by using Hunt's (1979) approximate solution. Finally, by using the Frobenius series, the analytic solution is derived. Due to the feature of Hunt's equation, the present analytic solution is accurate in shallow and deep waters, while it is less accurate in intermediate depth water. The validity of the analytic solution is demonstrated by comparison with numerical solutions. The analytic solution is also used to examine the effects of pit geometry and relative depth on wave transformation.