• Physical Therapy Korea
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• v.16 no.2
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• pp.50-58
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• 2009

The purpose of this study was to test that motor skill training enhance motor function and cerebellar development. Using an animal model of fetal alcohol syndrome-which equates peak blood alcohol concentrations across developmental period-critifical periods for the effect of alcohol on body and cerebellar weigh was examined. The effect of motor skill training on motor function and cerebellar development of rat exposed alcohol on postnatal days 4 through 10 were studied. Newborn rats were assigned to one of two groups: (1) Control group (CG), via artificial rearing to milk formula and (2) experimental groups (EG), via 4.5g/kg/day of ethanol in a milk solution. After completion of the treatments, the pups were fostered back to lactating dams, and wearing they were raised in standard caged until they were postnatal 48 days. Rats from experimental group of postnatal treatment then spent 10 days in one of two groups: Experimental group II (EGII) was had got motor skill training (training traverse a set of 6 elevated obstacles) for 4 weeks. Experimental group I (EGI) was not trained. Before sacrificing, the rat got examined two behavioral test, body weigh and cerebellar weigh, then coronal sections were processed. The section was investigated the Purkije cell in the cerebellum using light microscope. The results of this study were as follows. 1. In body weight test, the outcome of alcohol groups were significantly lower than the normal group. 2. In cerebellar weight test, the outcome of EGI were significantly lower than CG and EGII. 3. In motor behavioral test, the outcome of EGI was significantly lower than NG and EGII. 4. In Purkinje cells counting test, the outcome of EGI was significantly lower than the NG and EGII. These result suggest that improved motor function induced by motor skill training after postnatal exposure is associated with dynamically altered expression of Purkinje cells and that is related with cerebellar function. Also, these data can potentially serve as a model for therapeutic intervention.

• Land and Housing Review
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• v.15 no.2
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• pp.9-17
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• 2024

The prototypical building energy model is very useful in building energy policies, research, and technology development. A prototypical apartment model for detailed energy analysis was proposed by Seo et al. in 2014, but sufficient verification was not possible due to the lack of reliable measurement data in predicting the model's energy consumption. However, verification is now possible thanks to a recent study that analyzed the Household Energy Panel Survey (HEPS) data that is released annually by the Korea Energy Economics Institute (KEEI) and published apartment complex benchmark data. The data was used to calibrate the prototypical apartment energy model located in the central region and constructed between 1990 and 1999. The calibrated model was used to verify the other apartment building groups with respect to region and year of completion. Meteorological data for five representative cities each in the central and southern regions were used for the simulation. A majority of the 18 groups produced results that satisfied the MBE and cv(RMSE) criteria.

• Journal of the Korean earth science society
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• v.29 no.2
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• pp.140-150
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• 2008

In this study, a new teaching model was developed using concept maps and applied to the Earth Science I unit on diastrophism. We analyzed the effects of this model on students' scholastic achievement, ability to construct concept maps, and attitudes towards concept map lessons, in comparison to traditional teaching methods. The data was sampled from 128 second-year male high school students in Gyunggido, Korea. Although the results are not statistically significant, the new teaching model seems to have contributed to an increase in scholastic achievement as opposed to the traditional teaching models. We also found that the students to whom the new teaching model was applied showed both significant and positive effects in terms of scholastic achievement, the ability to construct a concept map, and changes in attitudes towards concept map lessons.

• Journal of the Korea Society of Computer and Information
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• v.9 no.4 s.32
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• pp.203-214
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• 2004

This paper presents a practical application of possibilistic programming in a information system projects planning model. The estimate of the parameters of the model is often a problematic task for the decision maker(DM), Who has imprecise information or express his considerations subjectively. In this case. possibilistic decision making models can provide an important aspect in handling practical decision making problems. We suggest CPM(Critical Path Method) applying possibilistic programming. CPM is an approach to planning and coordinating large projects by directing managerial focus to the project's most critical aspects and providing completion time of project and beginning time of each activity. This model is an aid in the control of considering aspiration levels by the DM, the fuzziness of decision making, and computational efficiency. The problem is solved by using GINO computer package and the best compromised solution is found.

• Korean Journal of Construction Engineering and Management
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• v.12 no.2
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• pp.81-88
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• 2011

Providers haven't recently had a flexible construction cost estimation system to meet various needs of consumers about public housing. So the subject of this study is to estimate construction cost reasonably in early project stage of public housing and then develop reliable means which is able to support construction cost management and establish a adequate funding investment plan as a provider. In this study, Regression analysis was performed by the case on 20 public apartment complex which were designed from the first half of 2007 to the first half of 2008. A total construction cost of construction, civil engineering, machinery, elevator, land scape, electricity and communication work was used as one sample for increasing explanation and representativeness of the case. In addition, The total construction cost which is devided into design, contract and completion cost was variously analysed for increasing relevance of model and actual utilization. The result of estimation model based on a total construction cost set up completion and design cost showed that error rate is within 2%, which is a excellent result. The estimation model of the construction cost developed by this study is expected to estimate approximate construction cost which is adjacent real construction cost in early stage of the project by using some data.

• Proceedings of the Korean Society of Toxicology Conference
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• 2006.11a
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• pp.55-64
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• 2006

The fetal central nervous system (CNS) is sensitive to diverse environmental factors, such as alcohol, heavy metals, irradiation, mycotoxins, neurotransmitters, and DNA damage, because a large number of processes occur during an extended period of development. Fetal neural damage is an important issue affecting the completion of normal CNS development. As many concepts about the brain development have been recently revealed, it is necessary to compare the mechanism of developmental abnormalities induced by extrinsic factors with the normal brain development. To clarify the mechanism of fetal CNS damage, we used one experimental model in which 5-azacytidine (5AZC), a DNA damaging and demethylating agent, was injected to the dams of rodents to damage the fetal brain. 5AzC induced cell death (apoptosis)and cell cycle arrest in the fetal brain, and it lead to microencephaly in the neonatal brain. We investigated the mechanism of apoptosis and cell cycle arrest in the neural progenitor cells in detail, and demonstrated that various cell cycle regulators were changed in response to DNA damage. p53, the guardian of genome, played a main role in these processes. Further, using DNA microarray analysis, tile signal cascades of cell cycle regulation were clearly shown. Our results indicate that neural progenitor cells have the potential to repair the DNA damages via cell cyclearrest and to exclude highly affected cells through the apoptotic process. If the stimulus and subsequent DNA damage are high, brain development proceeds abnormally and results in malformation in the neonatal brain. Although the mechanisms of fetal brain injury and features of brain malformation afterbirth have been well studied, the process between those stages is largely unknown. We hypothesized that the fetal CNS has the ability to repair itself post-injuring, and investigated the repair process after 5AZC-induced damage. Wefound that the damages were repaired by 60 h after the treatment and developmental processes continued. During the repair process, amoeboid microglial cells infiltrated in the brain tissue, some of which ingested apoptotic cells. The expressions of genes categorized to glial cells, inflammation, extracellular matrix, glycolysis, and neurogenesis were upregulated in the DNA microarray analysis. We show here that the developing brain has a capacity to repair the damage induced by the extrinsic stresses, including changing the expression of numerous genes and the induction of microglia to aid the repair process.

• Korean Management Science Review
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• v.25 no.3
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• pp.27-43
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• 2008

This study analyzes the changes of Gyeongju local society because of setting up low and intermediate level radioactive waste disposal site by using urban dynamics model. Specifically, after examining 'Gyeongju Long-Term Development Plan' announced in 2007, I establish the number of industries, population, gross local product, residents' income, and the long term employment condition as essential change-causing factors in Gyeongju local society based on the Big3 government project, and forecast it by using 'Gyeongju long-Term Development Plan' and all sorts of statistical data. In this stage, I assume 3 scenarios(basic, optimistic, and pessimistic view) to estimate the changes of local society more exquisitely, and scenarios are composed through mediation about variables of a growth rate and an inflow or outflow rate. The result shows that Gyeonaju local society would have growing changes by 2020. The essential change-causing factors are as follows. The case of population is estimated that it starts going down at the level of approximately 270 thousand by 2009, starts going up continuously after 2009, the year of completion of low and intermediate level radioactive waste disposal site, and increases from the level of about 300 thousand as minimum to 340 thousand as maximum in 2020. The estimates of other cases are made that the number of Industries has about 10 thousand increases, gross local product has almost 6 trillion increases, nominal gross national income doubles, as well as residences have approximately 280 thousand increases, and also made that employment condition also improves continuously, and diffusion ratio of house starts going up but the amount of supplies is a little bit insufficient in the long view.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.40 no.5
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• pp.461-466
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• 2012

This paper describes the development and test result of X-band Transmitter flight model(FM) of STSAT-3 by satellite research center(SaTReC), KAIST. The communication sub-system of STSAT-3 is consist of two different frequency band channels. S-band frequency is used for Telemetry & Command, and X-band frequency is used for mission data. Payload observations data in Mass Memory Unit (MMU) is modulated by QPSK modulator in X-band Transmitter, and then QPSK modulation signal is transmitted to antenna through transfer switch. In this Paper, we described the results of modulation, low-pass filter design, power amp development, and switch test. The FM XTU is delivered Spacecraft Assembly, Integration and Test(AIT) level through the completion of functional Test and environmental(vibration, thermal vacuum) Test successfully.

• Safety and Health at Work
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• v.5 no.3
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• pp.118-124
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• 2014

Background: Satisfactory completion of mine safety training is a prerequisite for being hired and for continued employment in the coal industry. Although training includes content to develop skills in a variety of mineworker competencies, research and recommendations continue to specify that specific limitations in the self-escape portion of training still exist and that mineworkers need to be better prepared to respond to emergencies that could occur in their mine. Ecological models are often used to inform the development of health promotion programs but have not been widely applied to occupational health and safety training programs. Methods: Nine mine safety trainers participated in in-depth semi-structured interviews. A theoretical analysis of the interviews was completed via an ecological lens. Each level of the social ecological model was used to examine factors that could be addressed both during and after mine safety training. Results: The analysis suggests that problems surrounding communication and collaboration, leadership development, and responsibility and accountability at different levels within the mining industry contribute to deficiencies in mineworkers' mastery and maintenance of skills. Conclusion: This study offers a new technique to identify limitations in safety training systems and processes. The analysis suggests that training should be developed and disseminated with consideration of various levels-individual, interpersonal, organizational, and community-to promote skills. If factors identified within and between levels are addressed, it may be easier to sustain mineworker competencies that are established during safety training.

• Korean Journal of Construction Engineering and Management
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• v.9 no.5
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• pp.127-136
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• 2008

The initial step in the construction process, estimating appropriate construction time and expense is the most important factor that would influence the result of the construction. In order to enhance productivity and efficiency, there is a need to analyze and manage rationally. The purpose of this project is to make a simulation model for all subway tunnel construction based on the NATM method, also give an support equipment that would make available to plan and analyze the construction. The development of simulation model is based on a real case construction analysis process and also on the reference data. It reflects restrictive elements, make it possible to modify the conditions, and not only adapt to our project's construction but other projects as well. The model developed by this project will be able to reasonably predict the construction completion time and support the process of decision making during the planning. Therefore we can expect the productivity and efficiency of the whole construction projects.