• Title/Summary/Keyword: Development Effect

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Geometry effect in the drug delivery for therapy with nanomedicines based on the conditions of the sport

  • Zhu, Lemei;Zou, Xuemin;Li, Xi;Zhang, Yuan;Liu, Juan;Xiang, Yuhan
    • Advances in nano research
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    • v.13 no.3
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    • pp.217-231
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    • 2022
  • This study investigates the geometrical impact on the nanomedicine drug delivery via nanodevices. A nanomotor made of the nanotube carrying the drug as the motor blade is considered in the blood flow. Physical activities change the blood flow, and sports training enhances the blood flow and plays a significant role in the stability of drug delivery devices. This paper studies the impact of geometrical parameters on the nanomotors carrying the nanomedicine. The effect of physical exercise on the dynamic response regarding the stability of drug delivery devices is discussed in detail.

The Relationship of Home Environments to Children's Social Development : Analysis of a Causal Model (가정환경변인과 아동의 사회적 능력간의 관계 : 인과 모형 분석)

  • Jang, Young Ae
    • Korean Journal of Child Studies
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    • v.8 no.2
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    • pp.17-44
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    • 1987
  • The study examined the characteristics of the relationship of home environment variables and children's social development. Two studies were conducted ; Study I examined (1) the correlation of home environment variables and children's social ability and (2) the predictability of home environment variables for children's social ability by children's age. Study II investigated the causal relationship among the variables which are supposed to affect children's social ability. The subjects of this study were 240 children at age four, six and eight attending nursery schools, kindergartens and elementary schools and their mothers. Instruments included the Inventory of Home Stimulation (HOME), the Inventory of Sociodemographic Variables, social maturation scale, and the social-emotional developmental rating scale. The results obtained from this study were as follows : 1) Home environment variables had a positive correlation with children's social development at age four and six, but at age eight, only HOME variables had a significant positive correlation with children's social development. 2) The home environmental variables that significantly predicted children's social development differed according to children's age. That is, play materials, economic status of the home, and parent education were predictive of children's social development at age four, while parent's education, fostering maturity and independence, and play materials were predictive at age six. Fostering maturity and independence, aspects of physical environment, and economic status of the home were predictive at age eight. 3) The causal model of home environment effect on children's social development was formulated by exogenous variables (parent education and economic status of the home) and endogenous variables (direct stimulation, indirect stimulation and the emotional climate of the home). 4) The results of the analysis of the causal model showed that the variables that have a direct effect on children's social development differed according to children's age. That is, direct stimulation had more effect on children's social development at earlier ages, and indirect stimulation had more effect on children's social development at later ages. Among socio-demographic variables, parent's education was most closely related to children's social development. The amount of variance that explained children's social development decreased with increase in children's age.

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The Effect of Maternal Parenting Style and Sensitivity on Infant Development (어머니의 양육유형 및 민감성이 영아의 발달에 미치는 영향)

  • Lee, Hyung-Min;Park, Sung-Yun;Seo, So-Jung
    • Journal of the Korean Home Economics Association
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    • v.46 no.2
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    • pp.97-111
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    • 2008
  • A total of 31 mothers of 5-month-old infants(18 boys and 13 girls) were observed and interviewed at home via a questionnaire format. Results revealed that perceived maternal parenting style had an effect on general infant general development. As mother exhibited more didactic and limit setting behaviors, the infants showed more receptive, expressive, and language development characteristics. Furthermore, the effects of maternal sensitivity on infant general development and language skills were also ascertained. The infants who showed more positive general development had mothers who interacted sensitively with them. Maternal sensitivity was the only factor that had a major effect on infant general development. The overall findings of this study indicate that perceived maternal parenting style and observed maternal sensitivity were found to have positive effects on general infant general development and language skills.

Effects of silkworm and its by-products on muscle mass and exercise performance in ICR mice.

  • Lee, Ji Hae;Jo, You-Young;Ju, Wan-Taek;Kim, Kee-Young;Kweon, HaeYong
    • International Journal of Industrial Entomology and Biomaterials
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    • v.39 no.1
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    • pp.34-38
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    • 2019
  • In this study, we investigated the effect of silkworm, and its by-products on exercise endurance, muscle mass, and fatigue recovery using ICR mice model. Powders of silkworm, pupae, dongchunghacho, and silk powder were suspended in water and feed to mice for 2 weeks. The forced swimming time was increased by 4.3, 4.1 and 2.8 seconds after silkworm, pupae, and dongchughacho administration compared to DW fed group. Increases in exercise ability were achieved by difference mechanism according to feeding materials. Pupae increased muscle mass by 129% compared with the control group which may effect on elongation of swimming time. Dongchunghacho improved the plasma concentrations of fatigue markers such as creatinine, blood urea nitrogen (BUN), and D-lactate. Silkworm administration showed dual effect, the muscle mass induction (114% vs. control) and anti-fatigue (plasma creatinine, BUN, and D-lactate were 63, 75, and 78% vs. con) effect which contributed most elongated swimming time. In conclusion, silkworm and its by-products including pupae and dongchunghacho with the predominant protein and bioactive components improved muscle mass and showed anti-fatigue effect which could promote exercise performance ability.

Effect of Soil Salinity Levels on Silage Barley Growth at Saemangeum Reclaimed Tidal Land

  • Lee, Sanghun;Bae, Hui-Soo;Lee, Soo-Hwan;Kang, Jong-Gook;Kim, Hong-Kyu;Lee, Kyeong-Bo;Park, Ki-Hoon
    • Korean Journal of Soil Science and Fertilizer
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    • v.46 no.5
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    • pp.365-372
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    • 2013
  • Crop development and nutrient availability are strongly influenced by soil salinity levels. This study was conducted to investigate the effect of rice straw and nitrogen (N) fertilizer for silage barley under various soil salinity levels at Saemangeum reclaimed tidal land. Three levels of rice straw (0, 2.5, 5.0 ton rice straw $ha^{-1}$) and N (0, 150, 225 kg N $ha^{-1}$) were applied at 0.04, 0.23, 0.35% soil salinity levels. Biomass yield of silage barley was influenced by the interactions between rice straw application and N fertilization. Although there was no single effect of rice straw application on biomass yield, it was significantly increased with N application and a rice straw application of 5.0 ton $ha^{-1}$. Sodium content in silage barley was significantly lower at 0.04% salinity level, and but it was statistically increased with increasing soil salinity levels. Forage qualities such as total digestible nutrients and relative feed value of silage barley were significantly higher with N application at 0.04% salinity level, but there was no effect of rice straw application. Soil organic matter content was increased with N and rice straw application regardless of soil salinity level. The results of this study showed that the effect of rice straw and N fertilization on silage barley was influenced by soil salinity levels, which indicates that the management practice of silage barley at Saemangeum reclaimed tidal land should consider soil salinity levels.

The Effects of Mathematical Games with Motion on Young Children's Development (운동요소가 포함된 수학게임이 유아발달에 미치는 효과)

  • Chang, Bo-Kyung
    • Korean Journal of Human Ecology
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    • v.19 no.2
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    • pp.271-283
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    • 2010
  • This study was planned to investigate the effects of mathematical games with motion on young children's development. The study was performed to compose mathematical games with motion and just mathematical games for young children. The games were set up to be executed 16 times for 8 weeks. The results of this study were as follows: Mathematical games with motion had a significant effect on young children's mathematical problem-solving ability. Mathematical games with motion had a significant effect in every category on young children's ability for motion competence and mathematical games with motion had a significant effect on young children's socio-emotional development. There were significant differences between the control group and the experimental group except for the independence from teachers and peer interaction. Mathematical games with motion had a significant effect on young children's language ability.

Financial Market Integration and Income Inequality

  • Jung, Jae Wook;Kim, Kyunghun
    • East Asian Economic Review
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    • v.25 no.2
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    • pp.175-203
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    • 2021
  • Over the past decades, financial markets have been integrated across countries while income inequality has increased in most countries. This paper studies the effect of financial market integration on income inequality and investigates whether this effect varies with the degree of financial market development. We find empirical evidence that financial market integration and financial market development interact to change income inequality. Specifically, the effect of financial market integration on income inequality is nonlinear, and the degree of financial market development plays an important role. Opening financial markets worsens income inequality in the countries holding the underdeveloped state of financial markets, however, the effect of capital account openness on income inequality is statistically insignificant in the countries with developed financial markets.

Effect of Senior Managers' Characteristics on Project Manager's Reporting Tendencies and Information Systems Development Performance (프로젝트 상급자 특성이 프로젝트관리자의 보고 성향과 시스템 개발성과에 미치는 영향)

  • Jang, Si-Young;Oh, Man-Seok
    • Journal of Information Technology Applications and Management
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    • v.19 no.2
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    • pp.149-179
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    • 2012
  • This study explores the reporting tendencies of project managers when sending a status reports to their respective senior managers in information systems development project. It also examines the effect of selective reporting on report quality and systems development performance. The research model is proposed based on literature survey as well as key points from Iacovou et al. [2009] which is an extension of selective reporting in information systems project. Analysis of responses from 257 project managers in information systems industry indicates that pessimistic reporting by project managers has negative effect on both report quality (mediator variable) and systems development performance, while optimistic reporting has no significant effect on systems development performance. The CEO interest has an impact on the senior manager's power, which in turn leads to optimistic reporting by project managers. The senior manager's character has an impact on the senior manager's leadership, which in turn leads to pessimistic reporting. No direct relationship exists either between CEO interest and optimistic reporting or between senior manager's character and pessimistic reporting. In addition, trust toward the senior managers is significantly related to pessimistic reporting. Finally, report tendencies are also found to be affected by the active/passive characteristics of project managers.

Evaluation of Topical Drug Containing Solcoseryl and Micronomicin on Surgical Wound in Mice

  • Chung, Kae-Jong;Chang, Man-Sik;Chun, Jong-Ok;Chun, Jae-Kwang;Kim, Sung-Chul;Park, Wahn-Soo;Lee, Hyang-Woo
    • Biomolecules & Therapeutics
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    • v.2 no.1
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    • pp.23-27
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    • 1994
  • Wound healing and antibacterial effects of solcoseryl-micronomicin combination gel on an open wound were studied in mice. A simple model was designed for assessing the effects. Using the model, we compared the efficacy of a combined topical gel of solcoseryl and micronomicin with those gels of solcoseryl or micronomicin alone. From the results of our experiment, the wound healing effect of open wounds by treatment with the combination gel was significantly enhanced when compared with those by treatment with solcoseryl gel or micronomicin gel alone. And the antibacterial effect of the combination gel was higher than those of solcoseryl gel or micronomicin gel alone.

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