• Asian Pacific Journal of Cancer Prevention
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• v.15 no.7
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• pp.3335-3341
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• 2014

Background: Severe toxicity is commonly observed in cancer patients receiving irinotecan (CPT-11) UDPglucuronosyltransferase1A1 (UGT1A1) catalyzes the glucuronidation of the active metabolite SN-38 but the relationship between UGT1A1 and severe toxicity remains unclear. Our study aimed to assess this point to guide clinical use of CPT-11. Materials and Methods: 89 cancer patients with advanced disease received CPT-11-based chemotherapy for at least two cycles. Toxicity, including GI and hematologic toxicity was recorded in detail and UGT1A1 variants were genotyped. Regression analysis was used to analyse relationships between these variables and tumor response. Results: The prevalence of grade III-IV diarrhea was 10.1%, this being more common in patients with the TA 6/7 genotype (5 of 22 patients, 22.7%) (p<0.05). The prevalence of grade III-IV neutropenia was 13.4%and also highest in patients with the TA 6/7 genotype (4 of 22 patients; 18.2%) but without significance (p>0.05). The retreatment total bilirubin levels were significantly higher in TA6/7 patients (mean, $12.75{\mu}mol/L$) with compared to TA6/6 (mean, $9.92{\mu}mol/L$) with p<0.05. Conclusions: Our study support the conclusion that patients with a $UGT1A1^*28$ allele (s) will suffer an increased risk of severe irinotecan-induced diarrhea, whether with mid-or low-dosage. However, the $UGT1A1^*28$ allele (s) did not increase severe neutropenia. Higher serum total bilirubin is an indication that patients UGT1A1 genotype is not wild-type, with significance for clinic usage of CPT-11.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.15 no.5
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• pp.235-243
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• 2020

The more consumers feel the brand as authentic, the better the brand image and the higher the purchase intention, so companies actively seek to build brand authenticity. On the other hand, the quality of products perceived by consumers comprehensively in consideration of various factors such as performance, durability, and materials can affect brand authenticity. The purpose of this study is to present useful implications by building a research model for quality and brand authenticity from a marketing point of view, and empirical analysis. For this, product quality and brand authenticity were theoretically defined, the relationship between them was identified, and ultimately the influence of these concepts on brand image was examined. In detail, a survey was conducted on a total of 286 consumers to find out the quality of the product, authenticity of the brand, and brand image, and the product to be surveyed was S20, the latest mobile phone of S Electronics. As a result of empirical analysis, although quality had a statistically significant positive effect on brand authenticity, the degree was not greater than expected. In addition, quality had a statistically significant positive effect on brand image, and its degree was large, but when quality and brand authenticity were considered together, it was found that the regression coefficient of brand authenticity was larger than that of quality. This means a partial mediating effect of brand authenticity. Therefore, in order to enhance the brand image and purchase intention of SMEs/Venture companies, a strategy that build brand authenticity simultaneously in consideration of the components presented in this study will be more effective than a strategy that focuses only on quality. This study proposes a variety of theoretical and practical implications by empirically examining the relationship between brand authenticity and brand image perceived by consumers through quality from a marketing perspective, based on a research model that was not discussed in previous studies. In particular, this study proposes a plan to build brand authenticity from the perspective of SMEs/Ventures.

• Journal of the Korean Society of Costume
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• v.62 no.4
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• pp.46-57
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• 2012

Consumers currently show cross-channel shopping behavior between the Internet and store-based retail types when searching information and purchasing sensory products such as fashion items to reduce risks. As consumers compare both types of stores before making a purchase decision, the Internet retail type and store-based retail type started conflicting/competing each other as the combined retail evolution theory proposed(Kim & Kincade, 2006). The purpose of this study is to examine consumers' cross-channel shopping behavior between the Internet and store-based retail types and their importance and satisfaction with information provided by the Internet retail stores. This study employs a quantitative research method using a survey. Demographics, types of stores used for purchase, satisfaction with the type of stores, Internet shopping behavior, importance and satisfaction with product information in the Internet retail stores were asked. MANOVA and descriptive statistics were used to test hypotheses. The result shows that a majority of participants(36.2%) shows cross-channel shopping behavior between the two retail types. Also, most participants(72.4%) decide on their purchase and are satisfied only after cross-channel shopping between the two retail types. Participants were grouped based on their information search and purchase behavior. Significant differences among the groups were found in importance and satisfaction with product information provided by the Internet stores. In measuring participants' satisfaction, a majority of participants(42.1%) showed satisfaction with their purchase at store-based retail stores after information search via the internet, followed by the satisfaction with the purchase at the internet retail stores after information search at store-based retail stores(30.3%). Fifty one point nine percent of participants search information via the internet(vs.48% at store-based retail stores), and they especially look for fiber contents and design details with pictures(37.4%). The satisfaction with price information provided by the Internet retail stores is the highest (m=3.70 out of 5.0) among fashion product information followed by design information(m=3.48). On the other hand, size information, refund/exchange and fiber content information received low satisfaction scores(m=2.81, 2.71, 2.57 in turn). This research suggests the Internet retail stores should provide more variety of information in detail using technology and improving customer services. This study could provide the Internet retail stores a guideline to establish a satisfactory information delivery system.

• Journal of The Korean Association of Information Education
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• v.6 no.3
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• pp.328-337
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• 2002

Looking at multimedia education contents from a design point of view, the instructor's design model may differ from the child's understanding model due to gap of the instructor's and child's knowledge. This fact implies it impacts the effectiveness of the education contents. The learning efficiency of Korean typography in WBI for children depends on the font-family, line space, font-size, the age of user, the output device such as the monitor, and other various factors. In this paper, we measured and analyzed on readability of Korean typography in WBI for children by reading speed method. The results of experiments show that readability depends on the font-family of typography, age(grade), and sex of children. In detail, "Goolymche" has the shortest time to be read, and girl and the highest grade students of elementary school have shorter time than boy and the lower grade students. Moreover, we consider the elegance of typography in WBI for holding children's interests because they prefer "Yopseoche". We provide some CSSs in WBI for children based on the experimental results, to used in school fields.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.27 no.4
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• pp.469-476
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• 2009

The new laser scanning technology allows to attain 3D information faster with higher accuracy on surface ground, vegetation and buildings of the earth surface. This acquired information can be used in many areas after modifying them appropriately by users. The contour production for accurate landform is an advanced technology that can reveal the mountain area landscapes hidden by the trees in detail. However, if extremely precise LiDAR data is used in constructing the contour, massive-sized data intricates the contour diagram and could amplify the data size inefficiently. This study illustrates the algorithm producing contour that is filtered in stages for more efficient utilization using the LiDAR contour produced by the detailed landscape data. This filtering stages allow to preserve the original landscape shape and to keep the data size small. Point Filtering determines the produced contour diagram shape and could minimize data size. Thus, in this study we compared experimentally filtered contour with the current digital map(1:5,000).

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.27 no.5
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• pp.619-628
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• 2009

LiDAR has capability of rapid data acquisition and provides useful information for reconstructing surface of the Earth. However, Extracting information from LiDAR data is not easy task because LiDAR data consist of irregularly distributed point clouds of 3D coordinates and lack of semantic and visual information. This thesis proposed methods for automatic extraction of buildings and 3D detail modeling using airborne LiDAR data. As for preprocessing, noise and unnecessary data were removed by iterative surface fitting and then classification of ground and non-ground data was performed by analyzing histogram. Footprints of the buildings were extracted by tracing points on the building boundaries. The refined footprints were obtained by regularization based on the building hypothesis. The accuracy of building footprints were evaluated by comparing with 1:1,000 digital vector maps. The horizontal RMSE was 0.56m for test areas. Finally, a method of 3D modeling of roof superstructure was developed. Statistical and geometric information of the LiDAR data on building roof were analyzed to segment data and to determine roof shape. The superstructures on the roof were modeled by 3D analytical functions that were derived by least square method. The accuracy of the 3D modeling was estimated using simulation data. The RMSEs were 0.91m, 1.43m, 1.85m and 1.97m for flat, sloped, arch and dome shapes, respectively. The methods developed in study show that the automation of 3D building modeling process was effectively performed.

• Journal of Korean society of Dental Hygiene
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• v.10 no.6
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• pp.1037-1048
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• 2010

Objectives : The awareness of health care need increasing attention from the public along with changing professional human-resources activity. As there are increasing social demand for the roles and professionalism of dental hygienists, the purpose of this study was to examine the job performance, creativity and organizational climate of dental hygienists by their own self-diagnostic evaluation in an attempt to help enhance their work ability. Methods : According to the data released as August 2008 by the Dental Association and public health centers in Gwangju, 735 dental hygienists worked at 425 dental clinics. The subjects in this study were 156 dental hygienists at 85 dental clinics who were selected by proportionate sampling method from among the dental hygienists. After an interview survey was conducted in person, the answer sheets from 132 respondents were analyzed except 24 incomplete ones. The questionnaire used in this study consisted of 49 items. A five-point Likert scale was used and SPSS 12.0 program was analyzed the data. Results : 1. As a result of checking the types of works, treatment cooperation(54%), and oral health education often(45%), They weren't responsible for preventive treatment(42%). 2. When they made a self-diagnostic evaluation of creativity and organizational climate, they put the highest value on their autonomy(2.21), followed by positive attitude(2.10). Out of seven organizational climate, challenging spirits(2.81) ranked highest, followed by reliability(2.66). 3. Major management eopmubyeol individual creativity compared with three business relationships and a positive attitude in the case of the high group received oral health education and care management services in a group doing the most was General office work and office assistance work in the medical assistance group that was doing business primarily. 4. In the relationship between self-assesment score and three performance duties, Positive difference was noted in the group with positive attitude and elevated autonomy in terms of performing oral health education. Conclusions : As a result, individual creativity and organization of the atmosphere, each detail, through analysis of the self-assessment model, developed guide on the investigation by doing a dental hygienist, a unique business promotion and Enlargement of the study suggested the need to be considered is.

• Journal of Korean Society for Geospatial Information Science
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• v.18 no.2
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• pp.29-33
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• 2010

The purpose of LiDAR ground classification is to archive both goals which are acquiring confident ground points with high precision and describing ground shape in detail. In spite of many studies about developing optimized algorithms to kick out this, it is very difficult to classify ground points and describing ground shape by airborne LiDAR data. Especially it is more difficult in a dense forested area like Korea. Principle misclassification was mainly caused by complex forest canopy hierarchy in Korea and relatively coarse LiDAR points density for ground classification. Unfortunately, a lot of LiDAR surveying performed in summer in South Korea. And by that reason, schematic LiDAR points distribution is very different from those of Europe. So, this study propose enhanced ground classification method considering Korean land cover characteristics. Firstly, this study designate highly confident candidated LiDAR points as a first ground points which is acquired by using big roller classification algorithm. Secondly, this study applied weighted gradient kernel(WGK) algorithm to find and include highly expected ground points from the remained candidate points. This study methods is very useful for reconstruct deformed terrain due to misclassification results by detecting and include important terrain model key points for describing ground shape at site. Especially in the case of deformed bank side of river area, this study showed highly enhanced classification and reconstruction results by using WGK algorithm.

• Journal of Korean Society for Geospatial Information Science
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• v.22 no.3
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• pp.39-46
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• 2014

Network RTK positioning, one of GNSS positioning systems, is currently very popular due to its easy operation and low cost. However, the network RTK positioning unquestioningly accepts observation result acquired with an ambiguity fixed-solution regardless of different field conditions and situations, and then it is applied to the practice. This paper, therefore, has investigated the effects of field conditions obtained network RTK survey data for the area with obstacles on the variation of positioning accuracy. Being explained in detail, after conducting survey by GPS-only positioning and combined GPS/GLONASS observations giving changes to the distance from obstacles and elevation angles, and then accuracy results of each positioning method were compared each other. As a result, while GPS-only point positioning method showed more stable results than combined GPS/GLONASS method in the areas with no obstacles, combined method gave better result than GPS-only for the areas with presence of obstacles. Based on the results of this experiment, when the further study is conducted with a variety of different field conditions affecting the survey accuracy, it can be expected that the accuracy of network RTK survey method would become to more popular.

• The Research Journal of the Costume Culture
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• v.18 no.2
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• pp.261-276
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• 2010

The analysis of an art trend in the principle dimension starts by observing the object of work in the perspective of formative composition and recognizing it as a universal system. It can be said that it is consistent with an interpretation method for a form theory of formal history by Heinrich W$\ddot{o}$lfflin, a leading form critic in art criticism. Hence, the purpose of this study was to find out what are the formative principles in Renaissance Classicism as a design principle to be applicable to modern fashion by reviewing the formative characteristics of Renaissance Classicism Architecture with which W$\ddot{o}$lfflin directly dealt. As for the theoretical literature review, I used W$\ddot{o}$lfflin's theoretical framework and looked at the Renaissance Classicism Architecture that he studied and examined the possibility of utilizing his theory as a layout principle and the characteristics. As for analysis of design cases, I applied the aforementioned architecture layout principle to modern fashion and conducted case study analysis to delve into distinctive layout principles found in fashion. The study showed that the Renaissance Classicism Architectural Style is marked by linearity, planarity, closing and multiple unity: linearity was expressed in the observation form in fixed frontal view and an emphasis on a tangible silhouette homeogenous and definite line structures; planarity was achieved in the form of paralleled layers of frontal view element, planarity style, and identical and proportional repetition of various sizes.; closing signified the pursuit of complete and clear regularity, and architecture developed in a constructive phase through organizational inevitability and absolute invariability.; multiple unity was expressed in self-completedness and independent parallel of discrete forms and harmony of emphasized individual elements in a totality. Applying these layout characteristics of the Renaissance Classicism Architectural style and to see their individual expressive features, I found out that in adopting layout principles of the Renaissance Classicism Architecture to modern fashion, it turned out to be an emphasis of individual silhouettes, a flattened space, completed objects, organic harmony among independent parts: the emphasis of individual silhouettes was expressed in individual definitiveness of formative lines of clothes in accordance with body joints and an emphasis on formative lines of clothes; the flattened space was marked by single layer structure, planarity of elements of clothes, and listing arrangement by appropriate proportion.; the completedness of the objects was expressed by the stationary state where overall image is fixed, the construction of homogeneous and complete space, and absolute inevitability of internal layout in proportion; lastly, organic harmony of independent parts was stressed in independent completedness of each detail, and organic harmony of the whole. The expressive features would lead to a unique expression style of linear emphasis, proportion, constructive forms, and two-dimensional arrangement. The meaning of this study is follows: The characteristics of art school of thought are given shape by appling & analysing the architectural layout principles of historical art school of thought to modern fashion in the view point of formal construction dimension. The applied possibility of historical art school of thought as the source of inspiration about the fashion design is extended.