• Title/Summary/Keyword: Degree of growth

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Hair Growth Effect of Herbal Extract Mixture Ahn Tonic in Mice (한방추출 천연혼합물의 탈모 유발 쥐에 대한 발모 효과)

  • Kwak, Jin Young;Koh, Young Mee;Ahn, Ji Sup;Park, Yang Chun;Ahn, Taek Won
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.33 no.6
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    • pp.363-369
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    • 2019
  • This paper aims to assess the effect of herbal extract mixture, Ahn Tonic, on hair growth and examine the stability of this percutaneous hair growth ointment. The hair on the back of the mice C57b1/6N was removed, and 1% of the TXN(testosterone) was then applied for a week to prevent the hair growth. The experimental group was then treated with Ahn Tonic, 0.2 mL per day. The degree of newly grown hair was observed with a vernier caliper. We also measured the proportion of the newly growing hair section to the entire shaved section in the 4th week and 8th week by distinguishing the section turning black from the shaved area. To observe the effect of the test chemical product on hair follicles and hair roots, the biopsy was executed between week 4 and week 8. Gene expressions, which operate as a factor for growing hair in the skin tissues extracted from each experimental animals, were also observed through a real-time PCR gene amplification method. The results showed that the Ahn tonic group had statistically significant hair restoring effect compared to the control group in terms of microscopy, biopsy, and gene expressions. Ahn Tonic is considered to have an impact on the hair growth.

Growth Characteristics and Yields of 3 Year Old Korean Ginseng with Different Planting Densities in Direct Seeding Cultivation (인삼 직파 3년생에서 재식밀도에 따른 품종별 생육특성)

  • Park, Hong Woo;Jang, In Bae;Kang, Seung Weon;Kim, Young Chang;Kim, Jang Uk;Bang, Kyong Hwan;Kim, Gi Hong;Hyun, Dong Yun;Choi, Jae Eul
    • Korean Journal of Medicinal Crop Science
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    • v.21 no.5
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    • pp.372-379
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    • 2013
  • The present study was investigated the effect of planting density on plant growth and yield of Panax ginseng C. A. Meyer. Sowing density is one of the most important factors affecting yield. The value of roots have affected by shape, color, weight and degree of disease injury in ginseng. Also, it needed to minimize elapsed time for 5 years including pre-planting field management and cultivation period. We were conducted to evaluate that planting densities and varieties on the growth, yield and missing rate. The direct sowing was treated seeds density as a four levels (seeds; 72, 90, 120, 144) and 10 different varieties with 3 years old ginseng roots. Root weight was significantly affected by planting density and variety, but the number of lateral root and yield were affected by only planting density. Growth index was related to variety and planting density. Also, Root shape index was affected by both varieties and planting densities. Suitable planting density and variety were 120 plant per 1.62 $m^2$ and Gopoong, respectively. Results showed that it was also a significant difference (p=5%) in variety of planting density on growth.

Growth of Dendranthema zawadskii in Chloride-containing De-icing Salt Areas Upon Treatment With Soil Amendments (제설제 피해지에서 토양개량제 처리에 따른 구절초의 생육특성 비교)

  • Ju, Jin-Hee;Yang, Ji;Park, Sun-Young;Yoon, Yong-Han
    • Journal of Environmental Science International
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    • v.30 no.3
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    • pp.235-243
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    • 2021
  • This study was conducted to investigate the growth of Dendranthema zawadskii in damaged soils when they are treated with improvement agents. The treatments consisted of a control (unamended field soil) and the application of a loess ball of 1 cm to the field soil. According to the degree of damage the de-icing agent had caused, the soils were divided into 3 areas (based on the yellowing of Pinus densiflora for. multicaulis in soil surveys): H (high saline), M (medium saline), and L (low saline). A total of six treatments were performed: D. zawadskiia plant without soil amendment (H; high saline soil, M; medium saline soil, L; low saline soil), and a D. zawadskiia plant with loess ball on the soil surface (H.L; high saline soil with loess ball, M.L; medium saline soil with loess ball, L.L; low saline soil with loess ball). The results showed that D. zawadskiia growth went from highest to lowest in the order: M.L > L.L > M > L > H.L > H. Plant growth results showed that soils treated with soil amendments (loess ball) were better for D. zawadskii growth than untreated soils.

Characterization of the host reaction of some citrus plants with Xanthomonas axonopodis pv. citri, causing citrus bacterial canker disease.

  • Myung, Inn-Shik;Hyun, Jae-Wook;Kim, Kwang-Sik;Lee, Sung-Chan;Lim, Han-Chul
    • Proceedings of the Korean Society of Plant Pathology Conference
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    • 2003.10a
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    • pp.120.3-121
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    • 2003
  • Relative degree of resistance of citrus to Xanthomonas axonopodis pv. citri, the causal bacterium of canker, was investigated. Growth rate of a bacterium in leaf tissues after infiltration, disease incidence, and percent of lesion area were compared. By using growth rate[(GR=(At - A$\sub$t-1/)/A$\sub$t-1] host plants were differentiated into susceptible and resistant. Growth rates reached to peak at 40 hrs after inoculation and then declined. The growth rate in leaf tissues of a moderately susceptible cultivar, Citrus sinensis vu. Lane late(sweet orange), was the highest, and those of C. unshiu ${\times}$ C. sinensis(kiyomi), C. junos(yuzu), [(Citrus. unshiu x C. sinensis) x C. reticulata] (shiranuhi), and C. unshiu(satuma mandarin) were similar. This result indicates that the growth rate of the bacterium in leaf tissues can be effectively used for evaluation of disease resistance for citrus plants to X. axonopodis pv. citri. The disease on sweet orange occurred earlier than relatively resistant citrus plants tested. The percent of lesion area on leaf was also higher in sweet orange than those of satsuma mandarin, shiranuhi and kiyomi, and yuzu. The disease severity was highest on sweet orange and followed by kiyomi, shiranuhi, satsuma mandarin, and yuzu.

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A LONGITUDINAL STUDY OF SOFT-TISSUE FACIAL PROFILE CHANGES IN KOREAN CHILDREN (한국인아동의 연조직측모의 성장변화에 관한 누년적 연구)

  • Chung, Kyu-Rhim
    • The korean journal of orthodontics
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    • v.19 no.1 s.27
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    • pp.7-20
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    • 1989
  • A serial cephalometric study was undertaken to define the growth of the soft tissue facial profile in Korean children. The sample was composed of 25 males and 15 females for whom yearly cephalometric records were taken from the ages of 6 to 13 years. From the tracings, points on skeletal and soft tissue profiles were located and recorded on magnetic tape utilizing a Calcomp Talos RP660 X-Y digitizer. Linear and angular measurements of soft tissues were made directly from tape in a Cyber 174-16 computer after cephalometric enlargement had been corrected. A statistical evaluation was made of the data and the average profile diagrams in male and female were described by a Calcomp 960 pen plotter. On the basis of the findings of this study, the following trends were established. 1. The most prominent growth in soft tissue facial profile thickness was the nose and the least was the forehead. 2. The general growth direction of the soft facial tissue to the cranium described the downward and forward. 3. The degree of soft tissue facial convexity was decidely more than that exhibited earlier in life even though the soft tissue chin had protruded to the cranium. 4. The measurements indicated a general tendency for males to have larger nose and more convex and long soft tissue facial profile than did females. 5. Males showed significantly more growth than females in base of the upper lip and height of the upper anterior facial profile. 6. There was a difference between males and females in the rates of soft tissue facial profile growth. 7. Korean children showed less convex in the soft tissue profile convexity than did American children.

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Involvement of Transient Receptor Potential Melastatin 7 Channels in Sophorae Radix-induced Apoptosis in Cancer Cells - Sophorae Radix and TRPM7 -

  • Kim, Byung-Joo
    • Journal of Pharmacopuncture
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    • v.15 no.3
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    • pp.31-38
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    • 2012
  • Sophorae Radix (SR) plays a role in a number of physiologic and pharmacologic functions in many organs. Objective: The aim of this study was to clarify the potential role for transient receptor potential melastatin 7 (TRPM7) channels in SR-inhibited growth and survival of AGS and MCF-7 cells, the most common human gastric and breast adenocarcinoma cell lines. Methods: The AGS and the MCF-7 cells were treated with varying concentrations of SR. Analyses of the caspase-3 and - 9 activity, the mitochondrial depolarization and the poly (ADPribose) polymerase (PARP) cleavage were conducted to determine if AGS and MCF-7 cell death occured by apoptosis. TRPM7 channel blockers ($Gd^{3+}$ or 2-APB) and small interfering RNA (siRNA) were used in this study to confirm the role of TRPM7 channels. Furthermore, TRPM7 channels were overexpressed in human embryonic kidney (HEK) 293 cells to identify the role of TRPM7 channels in AGS and MCF-7 cell growth and survival. Results: The addition of SR to a culture medium inhibited AGS and MCF-7 cell growth and survival. Experimental results showed that the caspase-3 and -9 activity, the mitochondrial depolarization, and the degree of PARP cleavage was increased. TRPM7 channel blockade, either by $Gd^{3+}$ or 2-APB or by suppressing TRPM7 expression with small interfering RNA, blocked the SR-induced inhibition of cell growth and survival. Furthermore, TRPM7 channel overexpression in HEK 293 cells exacerbated SR-induced cell death. Conclusions: These findings indicate that SR inhibits the growth and survival of gastric and breast cancer cells due to a blockade of the TRPM7 channel activity. Therefore, TRPM7 channels may play an important role in the survival of patients with gastric and breast cancer.

Computational Analysis of Tumor Angiogenesis Patterns Using a Growing Brain Tumor Model

  • Shim, Eun-Bo;Kwon, Young-Keun;Ko, Hyung-Jong
    • International Journal of Vascular Biomedical Engineering
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    • v.2 no.1
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    • pp.17-24
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    • 2004
  • Tumor angiogenesis was simulated using a two-dimensional computational model. The equation that governed angiogenesis comprised a tumor angiogenesis factor (TAF) conservation equation in time and space, which was solved numerically using the Galerkin finite element method. The time derivative in the equation was approximated by a forward Euler scheme. A stochastic process model was used to simulate vessel formation and vessel elongation towards a paracrine site, i.e., tumor-secreted basic fibroblast growth factor (bFGF). In this study, we assumed a two-dimensional model that represented a thin (1.0 mm) slice of the tumor. The growth of the tumor over time was modeled according to the dynamic value of bFGF secreted within the tumor. The data used for the model were based on a previously reported model of a brain tumor in which four distinct stages (namely multicellular spherical, first detectable lesion, diagnosis, and death of the virtual patient) were modeled. In our study, computation was not continued beyond the 'diagnosis' time point to avoid the computational complexity of analyzing numerous vascular branches. The numerical solutions revealed that no bFGF remained within the region in which vessels developed, owing to the uptake of bFGF by endothelial cells. Consequently, a sharp, declining gradient of bFGF existed near the surface of the tumor. The vascular architecture developed numerous branches close to the tumor surface (the brush-border effect). Asymmetrical tumor growth was associated with a greater degree of branching at the tumor surface.

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A Study on the Effects of Entry Barriers for the Stock Prices of Venture Businesses. (진입 장벽이 벤처기업 주가에 미치는 영향)

  • Oh Sung-Bae;Kim Dong-Hwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.6 no.5
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    • pp.384-390
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    • 2005
  • The purpose of this study is to test empirically the effects of Entry Barriers for the stock prices of Venture Business using the Ohlson Model which is modifying and extending in terms of growth and the potential growth energy. Because the traditional Ohlson model(1995) on which the firm's value is determined only based on abnormal earnings and book value have numerous limitations when we evaluate the value of venture Businesses with high technology and new emerging market. In order to overcome these limitations, We can introduce items of net sales growth ratios and industrial property-to-net asset ratios into as proxy variables of the growth and potential growth energy. In the process of analyzing these research tests, we have set three kinds of hypotheses and tested then empirically compared with KOSDAQ ordinary listing business and KOSDAQ venture businesses between long-term analysis and short-term analysis. According to the degree of concentration reflecting HHI index, our empirical research were performed in depth. Therefore, the results of this study show us that all three kinds of Hypotheses are accepted.

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FBAR Devices Fabrication and Effects of Deposition Temperature on ZnO Crystal Growth for RF Filter Applications (RF 필터응용을 위한 FBAR 소자제작과 증착온도가 ZnO 박막의 결정성장에 미치는 영향)

  • Munhyuk Yim;Kim, Dong-Hyun;Dongkyu Chai;Mai Linh;Giwan Yoon
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2003.05a
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    • pp.88-92
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    • 2003
  • In this paper, the characteristics of the ZnO films deposited on AI bottom electrode and the temperature effects on the ZnO film growth are presented along with the fabrication and their evaluation of the film bulk acoustic wave resonator (FBAR) devices. All the films used in this work were deposited using a radio-frequency (RF) magnetron sputtering technique. Growth characteristics of the ZnO films are shown to have a strong dependence on the deposition temperatures ranged from room temperature to 35$0^{\circ}C$ regardless of the RF power applied for sputtering the ZnO target. In addition, according to the growth characteristics of the distinguishably different micro-crystal structures and the degree of the c-axis preferred orientation, the deposition temperatures can be divided into 3 temperature regions and 2 critical temperatures in-between. Overall, the ZnO films deposited at/below 20$0^{\circ}C$ are seen to have columnar grains with a highly preferred c-axis orientation where the full width at half maximum (FWHM) of X-ray diffraction rocking curve is 14$^{\circ}$. Based on the experimental findings, several FBAR devices were fabricated and measured. As a result, the FBAR devices show return loss of ~19.5dB at resonant frequency of ~2.05GHz.

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Innovation and Intangible Capital for Economic Growth (혁신과 무형자본을 통한 경제성장)

  • Kim, Nari
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.9
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    • pp.454-464
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    • 2018
  • The OECD estimates that a high concentration of intangible capital is in the richest countries of the world. Studies show that intangibles have a positive relation with economic growth. However, different types of intangibles can have different impacts on economic performance. Therefore, this paper attempts to distinguish the differences within the intangibles in influencing economic growth by analyzing three different characteristics of the intangibles. Three main types of intangibles (computerized information, innovative property and economic competencies) are analyzed based on the degree of tacitness, the process of creation and diffusion, and the level of embedded value-added. This research uses Polanyi's classification of tacitness of knowledge, the Nonaka-Takeuchi Model and the "smiling curve" to find that not only investing more in intangible capital but also developing more "tacit" type of intangibles are important for economic growth.