• Title/Summary/Keyword: DON

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Survey on Contamination of Fusarium Mycotoxins in 2011-harvested Rice and Its By-products from Rice Processing Complexes in Korea (미곡종합처리장에서 수집한 2011년산 쌀과 부산물의 Fusarium 곰팡이독소 오염 실태)

  • Lee, Soohyung;Lee, Theresa;Kim, Mija;Yu, Ohsuk;Im, Hyunjin;Ryu, Jae-Gee
    • Research in Plant Disease
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    • v.19 no.4
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    • pp.259-264
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    • 2013
  • To investigate Fusarium mycotoxin contamination in rice samples from rice processing complexes (RPCs), paddy rice and rice-milling products such as husks, brown rice, blue-tinged rice, broken rice, rice bran, discolored rice, and polished rice were collected from nationwide in 2012. Three hundred seventy one samples of rice and its by-products were analyzed for three trichothethenes including nivalenol (NIV), deoxynivalenol (DON), and zearalenone (ZEA) by LC/MS. Discolored rice samples were found to have the highest contamination of DON, NIV or ZEA, followed by broken rice. Polished rice samples were largely free from mycotoxins, except three samples which were contaminated with NIV or DON at safety level. The rice byproduct samples were contaminated at higher level and frequencies than polished rice samples.

Comparative Pathogenicity of Fusarium graminearum Isolates from Wheat Kernels in Korea

  • Shin, Sanghyun;Son, Jae-Han;Park, Jong-Chul;Kim, Kyeong-Hoon;Yoon, Young-mi;Cheong, Young-Keun;Kim, Kyong-Ho;Hyun, Jong-Nae;Park, Chul Soo;Dill-Macky, Ruth;Kang, Chon-Sik
    • The Plant Pathology Journal
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    • v.34 no.5
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    • pp.347-355
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    • 2018
  • Fusarium head blight (FHB) caused by Fusarium species is a major disease of wheat and barley around the world. FHB causes yield reductions and contamination of grains with trichothecene mycotoxins including; nivalenol (NIV), deoxynivalenol (DON), 3-acetyldeoxynivalenol (3-ADON), and 15-acetyldeoxynivalenol (15-ADON). The objectives of this study were to identify strains of F. graminearum isolated in Korea from 2012-harvested wheat grain and to test the pathogenicity of these NIV- and DON-producing isolates. Three hundred and four samples of wheat grain, harvested in 2012 in Chungnam, Chungbuk, Gyeongnam, Jeonbuk, Jeonnam, and Gangwon provinces were collected. We recovered 44 isolates from the 304 samples, based on the PCR amplification of internal transcribed spacer (ITS) rRNA region and sequencing. Our findings indicate that F. asiaticum was the predominant (95% of all isolates) species in Korea. We recovered both F. asiaticum and F. graminearum from samples collected in Chungnam province. Of the 44 isolates recovered, 36 isolates had a NIV genotype while 8 isolates belonged to the DON genotype (3-ADON and 15-ADON). In order to characterize the pathogenicity of the strains collected, disease severity was assessed visually on various greenhouse-grown wheat cultivars inoculated using both NIV- and DON-producing isolates. Our results suggest that Korean F. graminearum isolates from wheat belong to F. asiaticum producing NIV, and both F. graminearum and F. asiaticum are not significantly different on virulence in wheat cultivars.

Antioxidative and Antiaging Activities and Component Analysis of Lespedeza cuneata G. Don Extracts Fermented with Lactobacillus pentosus

  • Seong, Joon Seob;Xuan, Song Hua;Park, So Hyun;Lee, Keon Soo;Park, Young Min;Park, Soo Nam
    • Journal of Microbiology and Biotechnology
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    • v.27 no.11
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    • pp.1961-1970
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    • 2017
  • Lespedeza cuneata G. Don is a traditional herb that has been associated with multiple biological activities. In this study, we investigated the antioxidative/antiaging activities and performed an active component analysis of the non-fermented and fermented (using Lactobacillus pentosus) extracts of Lespedeza cuneata G. Don. The antioxidative activities of the fermented extract were higher than those of non-fermented extracts. The elastase inhibitory activity, inhibitory effects on UV-induced MMP-1 expression, and ability to promote type I procollagen synthesis were investigated in Hs68 human fibroblasts cells. These tests also revealed that the fermented extract had increased antiaging activities compared with the non-fermented extract. A component analysis of the ethyl acetate fractions of non-fermented and fermented extracts was performed using TLC, HPLC, and LC/ESI-MS/MS to observe changes in the components before and after fermentation. Six components that were different before and after fermentation were investigated. It was thought that kaempferol and quercetin were converted from kaempferol glucosides and quercetin glucosides, respectively, via bioconversion with the fermentation strain. These results indicate that the fermented extract of L. cuneata G. Don has potential for use as a natural cosmetic material with antioxidative and antiaging effects.

Consideration of Don't-care Condition for Multiplexer-based Logic Design (For Application to Arduino-based Design Education) (다중화기 기반 논리 설계를 위한 무정의 조건의 고찰 (아두이노 설계 교육에의 활용을 위한))

  • Lee, Jae Min
    • Journal of Digital Contents Society
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    • v.18 no.5
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    • pp.881-888
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    • 2017
  • Logic design using multiplexer has been used as a useful method for design convenience and flexibility in structural digital system design. In this paper, we analyze the effect of don't care conditions on logic optimization in a multiplexer-based logic design, which was not discussed enough in the previous studies in multiplexer based logic design, and describe the use of don't care conditions for designing of a single multiplexer and multiple multiplexer-based logic design. Especially, the design method when the number of data input is not 2m (as the number of selection lines is m) is considered. We also describe how to apply the proposed technique to the digital logic design education in conjunction with microprocessor design using Arduino which is widely used in creative engineering education recently.

The Identity of Morisco in Don Quijote de La Mancha (『돈키호테』에 나타난 모리스꼬의 정체성을 중심으로)

  • LIM, Juin
    • Cross-Cultural Studies
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    • v.38
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    • pp.265-295
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    • 2015
  • This article is concerned about a reason for which Cervantes participates an arabic author named Benengeli and morisco translator in his work instead of christian author. From the multi-cultural point of view, the time in which Don Qujote was published, belongs to the Golden Age. In other words, the society can not be supported by the ideology of Purity of Blood in that the morisco, converso (Christian Jewish) have been permitted to coexist in the name of christian proselyte or New Christian despite of invisible discrimination. An invisible discrimination is based on the prejudice and negative stereotype of Old Christian against the New Christian. Cervantes offers an o open space for readers to participate in the creative reading, giving up the absolute authority of author named Benengeli. The deep-rooted prejudice against morisco or muslim author makes the readers of Don Quijote do reinterpret the contents and have question about his sincerity. This disbelief is partly on the basis of hypothesis that Don Quijote would be passed on orally by an arabic or morisco. Leaving the hypothesis alone, Romance, festival performances of morisco or the aljamia literature in the Iberian Peninsula have the chivalry or knights of the Occident. The chivalry in Romance of morisco means that morisco would seek assimilation into the mainstream of Occidental Christian community. At the same time, morisco would be faced with the dilemma of loss of religious identity. But Taqiyya, islamic doctrine, offsets the dilemma between yearning to assimilate into mainstream and religious conscience of morisco in that Taqiyya permits morisco to convert to Christianity in case that they are in danger of life or the following risk. From this point of view, There is no room for doubt about the fact that Taqiyya contributed to social assimilation or multicultural society of the Iberian Peninsula. It has been a long time since a narrow-minded religious dogma and ideology became a anachronistic relic in multicultural society of Spain such as the Purity of Blood. From a relative viewpoint, Don Quijote provides a ground for the collective intelligence among christian, muslim(morisco) and converso through a liberal community between readers and authors who form a pluralistic society.

Screening of mulberry varieties for larval growth, cocoon yield, and quality through silkworm rearing

  • Merlita A. Dacayanan;Crestilyn N. Damasco;Jarson P. Libunao;Mario B. Sampaga;Edna A. Galano
    • International Journal of Industrial Entomology and Biomaterials
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    • v.46 no.1
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    • pp.1-8
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    • 2023
  • Mulberry (Morus spp.) production is a vital activity in sericulture along with rearing of silkworms (Bombyx mori L.) for silk production. The Sericulture Research and Development Institute (SRDI) conducted a study that evaluated 11 mulberry varieties, including nine newly-evolved mulberry hybrids and two check varieties. These mulberry varieties were fed to silkworm hybrid, DMMMSU 115 x 100. The rearing performance of DMMMSU 115 x 100 was determined based on the silkworm economic traits such as weight of 10 matured larvae, cocoon weight, shell weight, shell percentage, cocoon yield, reelability percentage, filament length and filament size. Six silkworm rearing trials were conducted with 50 silkworm larvae per treatment in three replicates. The data were analyzed in a one-way Analysis of Variance. Significant differences were tested further using Tukey's Honest Significant Difference. Mulberry varieties that garnered an evaluation index value of higher than 50 were identified and selected. Results of the study revealed significant variations among the mulberry varieties based on the parameters gathered except on the reelability of cocoons, filament length and size. Matured silkworm larvae fed with Alf 55 were significantly heavier and higher cocoon yield compared to those fed with Alfonso and S54. Alf 32, Alf 55, Alf 58, Bat 37 and Bat 73 were identified as potential varieties and highly recommended as feed for the silkworm hybrid, DMMMSU 115 x DMMMSU 100.

Role of PKR and EGR-1 in Induction of Interleukin-S by Type B Trichothecene Mycotoxin Deoxynivalenol in the Human Intestinal Epithelial Cells (B형 트리코테센 곰팡이 독소 데옥시니발레놀에 의한 인체 장관 상피세포 염증성 인터루킨 8유도에서의 PKR과 EGR-1의 상호 역할 규명)

  • Park, Seong-Hwan;Yang, Hyun;Choi, Hye-Jin;Park, Yeong-Min;Ahn, Soon-Cheol;Kim, Kwan-Hoi;Lee, Soo-Hyung;Ahn, Jung-Hoon;Chung, Duk-Hwa;Moon, Yu-Seok
    • Journal of Life Science
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    • v.19 no.7
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    • pp.949-955
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    • 2009
  • Mucosal epithelia sense external stress signals and transmit them to the intracellular cascade responses. Ribotoxic stress-producing chemicals such as deoxynivalenol (DON) or other trichothecene mycotoxins have been linked with gastrointestinal inflammatory diseases by Fusarium-contamination. The purpose of this study was to test the hypothesis that DON evokes the epithelial sentinel signals of RNA-dependent protein kinase (PKR) and early growth response gene 1 (EGR-1), which together contribute to the pro-inflammatory cytokine interleukin 8 (IL-8) in human intestinal epithelial cells. PKR suppression by the dominant negative PKR expression attenuated DON-stimulated interleukin-8 production. Moreover, 1L-8 transcriptional activation by DON was also reduced by PKR inhibition in the human intestinal epithelial cells. Treatment with the PKR inhibitor also suppressed EGR-1 promoter activity, mRNA and protein induction, although mitogen-activated protein (MAP) kinases such as extracellular signal-regulated protein kinases (ERK) 1/2, p38, c-Jun N-terminal Kinase (INK) were little affected or even enhanced in presence of a PKR inhibitor. These patterns were also compared in the EGR-1-suppressed cells, which showed much more suppressed production of 1L-8. All things taken into consideration, DON-activated sentinel signals of EGR-1 via PKR mediated interleukin-8 production in human intestinal epithelial cells, which provide insight into the possible general mechanism associated with mucosal inflammation as an intestinal toxic insult by ribotoxic trichothecene mycotoxins.

Obliteration of alterity and death as the limit of it in Don DeLillo's White Noise (돈 드릴로의 "백색 소음"에 나타난 타자성의 소멸과 그 한계로서의 죽음)

  • Lee, Bok-Ki
    • English Language & Literature Teaching
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    • v.12 no.3
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    • pp.227-242
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    • 2006
  • In a post-modern society where things exist and events happen in the form of Baudrillardian simulation, alterity of the other is erased and transcendence is denied. Don DeLillo's White Noise depicts what may happen in a society where alterity and transcendence are experienced in the neutral and safe forms. It will be argued in this paper that such phenomena reflect the desire of the self to conquer the others and neutralize the existence of them for the self's enduring safety and accomplishment. However, the attempt must fail due to inevitable death. The invincibility of death reminds one of the limit of his ability and the existence of uncontrollable part of the other. This paper will focus on DeLillo's critique of such a society, the affect of the existence of death as an invincible force, and his message about the way to live under these conditions.

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A Kernel-Based Partitioning Algorithm for Low-Power, Low-Area Overhead Circuit Design Using Don't-Care Sets

  • Choi, Ick-Sung;Kim, Hyoung;Lim, Shin-Il;Hwang, Sun-Young;Lee, Bhum-Cheol;Kim, Bong-Tae
    • ETRI Journal
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    • v.24 no.6
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    • pp.473-476
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    • 2002
  • This letter proposes an efficient kernel-based partitioning algorithm for reducing area and power dissipation in combinational circuit designs using don't-care sets. The proposed algorithm decreases power dissipation by partitioning a given circuit using a kernel extracted from the logic. The proposed algorithm also reduces the area overhead by minimizing duplicated gates in the partitioned sub-circuits. The partitioned subcircuits are further optimized utilizing observability don't-care sets. Experimental results for the MCNC benchmarks show that the proposed algorithm synthesizes circuits that on the average consume 22.5% less power and have 12.7% less area than circuits generated by previous algorithms based on a precomputation scheme.

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A Case of Allergic Contact Dermatitis Improved after Korean Medicine Treatment Administration (한방 치료 후 호전된 알레르기성 접촉피부염 치험 1례)

  • Bae, Hyo-Bin;Yoon, Hwa-Jung;Ko, Woo-Shin
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.31 no.2
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    • pp.123-132
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    • 2018
  • Objectives : The purpose of this report is to know the effect of Korean medicine treatments on Allergic Contact Dermatitis. Methods : We treated a 63-years-old man patient with Allergic Contact Dermatitis on the left medial calf with Korean medicine. After Korean medical treatment for 26 days, we identified a reduction in size of erythema and loss of color fading, exudates and edema. We recorded pictures of changes on symptoms. Results & Conclusions : The symptoms of Allergic Contact Dermatitis were improved. Erythema, edema, exudate were lost. Thus Korean medicine treatments are effective on allergic contact dermatitis.