• Title/Summary/Keyword: DG

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The effects of Danggwisusan on restoration ability in wound induced animal models (당귀수산(當歸鬚散) 주정 추출물이 외상성 창상(外傷性 創傷) 병태모델의 회복능력에 미치는 영향)

  • Bak, Ji Won;Sim, Boo Yong;Kim, Dong Hee
    • The Korea Journal of Herbology
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    • v.29 no.5
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    • pp.55-63
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    • 2014
  • Objectives : The purpose of this study was verification of the restoration ability effect of Danggwisusan extract(DG) in wound induced Rat. Methods : It needed to make a scar(around $2{\times}2cm^2$) on the top of the fascia in the back of the rats and then the rats were divided into 4groups(n=6). Control was not treated at all, where as DG was orally medicated DG, Terra was percutaneously applied Terramycin, and DG + Terra was both orally medicated DG and percutaneously applied Terramycin per day for three weeks. Results : 93% or higher cell viability was observed in all tested groups from 1, 10, $100{\mu}g/m{\ell}$ in RAW 264.7cells. The DG decreased NO and cytokine production activity dose dependently. The production of IL-$1{\beta}$, IL-6 and TNF-${\alpha}$ were decreased by 46%, 46% and 40% in DG treated $100{\mu}g/m{\ell}$. The size of wound was significantly decreasing in DG, Terra, DG + Terra. WBC was significantly reduced in DG and DG + Terra. Monocyte was significantly reduced in DG, Terra and DG + Terra. Neutrophil was also reduced in DG, DG + Terra but not meaningless. The mRNA expression of MMP-1 was significantly reduced in Terra, MMP-2 was significantly reduced in DG, Terra, DG + Terra, and MMP-9 was significantly reduced in DG + Terra. Conclusions : According to the results, we thought that DG showed anti-inflammatory activities on the RAW 264.7cells in mouse macrophage and in adult rat wound. Moreover, the progress of recovery was found visually, heamatologically, genetically and histopathologically. In conclusion, it could be thought that DG has effect on the treating of wound.

A Comparative Study on the Effect of Commercialized Immobilized Lipases on the Selective Synthesis of 1,3-Diglyceride (1,3-디글리세리드의 선택적 합성에 있어서 상용 고정화 효소의 영향에 관한 비교 연구)

  • Chung, Dae-Won;Cho, Mi-Hye
    • Applied Chemistry for Engineering
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    • v.21 no.4
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    • pp.452-456
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    • 2010
  • It is known that 1,3-diglyceride (1,3-DG) hardly accumulates inside human body because the metabolism of 1,3-DG is entirely different from that of general fats such as triglycerides (TG). This research focuses on the selective synthesis of 1,3-DG by the esterification reaction using an immobilized lipase. For a reaction between glycerin and oleic acid (OA) with a mole ratio of 1 : 2 under vacuum, changes in the compositions of monoglyceride (MG), TG and DG and the contents of 1,3-isomers in DG were investigated, as a function of reaction temperature and the amount of lipase. The reactivities determined by the rate of the consumption of OA became higher with the increase in temperature and the amount of lipase. When the results were compared with those obtained in the earlier study where Novozym was applied as an immobilized lipase, the reactivity was higher for Novozym, on the other hand, selectivity to 1,3-DG was much higher for Lipozyme. Especially, it is remarkable that 1,3-DG content in total DG reached to 98% in the reaction carried out at $50^{\circ}C$ using Lipozyme.

Study on the Immobilized Lipase-Mediated Selective Synthesis of 1,3-Diglyceride (고정화 효소를 이용한 1,3-디글리세리드의 선택적 합성에 관한 연구)

  • Chung, Dae-won;Cho, Mi Hye
    • Applied Chemistry for Engineering
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    • v.20 no.4
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    • pp.443-448
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    • 2009
  • It is known that 1,3-diglyceride (1,3-DG) hardly accumulates inside human body because the metabolism of 1,3-DG is entirely different from that of general fats such as triglycerides (TG). This research focuses on the selective synthesis of 1,3-DG by the esterification reaction using an immobilized lipase. For a reaction between glycerin and oleic acid (OA) with a mole ratio of 1 : 2 under vacuum, changes in the compositions of monoglyceride (MG), TG and DG and the contents of 1,3-isomers in DG were investigated, as a function of reaction temperature and the amount of lipase. The reactivities determined by the rate of the consumption of OA became higher with increased in temperature and the amount of lipase. Changes in the compositions of MG, DG and TG, however, occurred after the DG content reached maximum, which were found to be dependent on various factors. TG was a main product, and significant decrease in the amount of both 1,3-DG and DG were observed, when reactions were carried out at high temperatures or when 10 wt% of lipase was used.

Streptomyces sp. DG-2 with Anti-MRSA (Methicillin Resistant Staphylococcus aureus) Activity (항 MRSA (Methicillin Resistant Staphylococcus aureus) 활성을 나타내는 Streptomyces sp. DG-2)

  • Jeong, Seong-Yun
    • Journal of Marine Bioscience and Biotechnology
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    • v.9 no.2
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    • pp.49-57
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    • 2017
  • We isolated marine bacterium, isolate DG-2 which produces the antibiotics against MRSA (methicillin-resistant Staphylococcus aureus). This isolate DG-2 was examined by its morphological, biochemical properties, and 16S rRNA sequencing analysis. And then, isolate DG-2 was identified to the genus Streptomyces. Therefore, this isolate was designated as Streptomyces sp. DG-2. Streptomyces sp. DG-2 grew relatively well at $25^{\circ}C$, pH 7.0, and NaCl 1.0%. For the pre-purification of the bioactive compounds, DG-2 was fermented in 30 L PPES-II medium, and the culture filtrates of DG-2 was extracted by ethyl acetate. The ethyl acetate extract of DG-2 showed the significant anti-MRSA and antibacterial activities.

Optimal Operating Strategy of Distributed Generation Considering Hourly Reliability Worth (시간별 신뢰도 가치를 고려한 분산전원의 최적 운영전략)

  • 배인수;신동준;김진오
    • The Transactions of the Korean Institute of Electrical Engineers A
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    • v.52 no.8
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    • pp.457-462
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    • 2003
  • This paper presents an optimal operating strategy of distributed generation (DG) with reliability worth evaluation of distribution systems. Using DG for peak-shaving unit could reduce the overall system operating cost, and using DG for standby power unit could reduce the customer interruption cost. If DG operating cost is less than utility power cost in peak time, DG should be running to reduce the overall system operating cost. When customer interruption cost enlarges, however, standby power strategy may be the better operating strategy than peak-shaving strategy. Selection of whether DG should be operated for peak-shaving or for standby power, needs the accurate reliability worth evaluation and the accurate power cost evaluation. Instead of using annual average reliability worth, the concept of hourly reliability worth is introduced in this paper to determine the optimal operating decision of DG. Applying suggested hourly reliability worth, the distribution companies that possess DG could set up the optimal operating strategy of DG.

LAN-Based Protective Relaying for Interconnect Protection of Dispersed Generators (LAN을 이용한 분산전원 연계 계통의 보호)

  • Jyung, Tae-Young;Baek, Young-Sik
    • Proceedings of the KIEE Conference
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    • 2005.11b
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    • pp.96-98
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    • 2005
  • 분산전원(Dispersed Generators)이 계통과 연계된 상태로 운전함에 따라 단방향의 전력 조류만을 고려하여 운영되던 기존의 배전 시스템에 여러 가지 새로운 영향을 미치게 되었다. 따라서 배전계통에 설치된 보호 장치들은 발전기 자체의 고장은 물론 계통 상황에 적절히 대처하여 운전할 수 있도록 고안되어져야 한다. 특히 DG가 연계되어 있는 배전선에서의 사고는 배전용 차단기의 동작으로 DG의 단독운전이 발생 할 수 있다. DG의 단독운전은 인명피해, 기기손상, 전력품질저하, 계통 복구의 어려움 둥 많은 문제가 있으므로 사고시 DG를 신속히 계통으로부터 분리해 주어야 한다. 그러나 DG가 연계된 배전선 이외(인접 배전선)의 고장에 대해서는 DG가 불필요하게 계통으로부터 분리되는 것을 예방하고 사고가 계통에서 제가 될 때까지 정상적으로 동작하게 하여야 한다. 따라서 DG 연계 배전선과 인접 배전선의 고장을 명확히 구분하는 것이 중요하다. 본 논문에서는 DG 연계 배전선과 인접 배전선의 고장 구분을 위해서 Network 상의 IED(Intelligent Electronic Device)에서 제공되는 Data통하여 HMI내에서 DG 연계 배전선과 인접 배전선의 사고판단을 하고 결과를 각 계전기로 보내 동작유무를 결정한다.

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The Inter-tie Protection Schemes of the Utility Interactive Dispersed Generation Units for Distribution Automatic Reclosing

  • Park, Joon-Ho;Kim, Jae-Chul;Moon, Seung-Il
    • KIEE International Transactions on Power Engineering
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    • v.2A no.4
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    • pp.166-173
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    • 2002
  • Dispersed Generation (DG) units significantly effect the existing distribution protection practices. Therefore, new protection practices of the distribution system interconnected with DG units should be reevaluated and developed. In this paper, a new inter-tie protection scheme of DG units for distribution automatic reclosing is proposed. The impact of DG units on existing radial-sectionaliser coordination is analyzed. And the effects of the distribution reclosing type (radial and passive reclosing) on DG dynamics are analyzed and classified. From the results of the DG dynamic responses by the reclosing type, i.e. radial and passive reclosing, the inter-tie protection schemes of DG are introduced to improve the reliability and availability of utility interactive DG. The proposed schemes are proved and evaluated by a case study using PSCAD/EMTDC simulation.

Theoretical Study of Electron Mobility in Double-Gate Field Effect Transistors with Multilayer (strained-)Si/SiGe Channel

  • Walczak, Jakub;Majkusiak, Bogdan
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.8 no.3
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    • pp.264-275
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    • 2008
  • Electron mobility has been investigated theoretically in undoped double-gate (DG) MOSFETs of different channel architectures: a relaxed-Si DG SOI, a strained-Si (sSi) DG SSOI (strained-Si-on-insulator, containing no SiGe layer), and a strained-Si DG SGOI (strained-Si-on-SiGe-on-insulator, containing a SiGe layer) at 300K. Electron mobility in the DG SSOI device exhibits high enhancement relative to the DG SOI. In the DG SGOI devices the mobility is strongly suppressed by the confinement of electrons in much narrower strained-Si layers, as well as by the alloy scattering within the SiGe layer. As a consequence, in the DG SGOI devices with thinnest strained-Si layers the electron mobility may drop below the level of the relaxed DG SOI and the mobility enhancement expected from the strained-Si devices may be lost.

Comparison of Diglyceride, Conjugated Linoleic Acid, and Diglyceride-Conjugated Linoleic Acid on Proliferation and Differentiation of 3T3-L1 Preadipocytes

  • Jeong, Jae-Hwang;Lee, Sang-Hwa;Hue, Jin-Joo;Lee, Yea-Eun;Lee, Young-Ho;Hong, Soon-Ki;Jeong, Seong-Woon;Nam, Sang-Yoon;Yun, Young-Won;Lee, Beom-Jun
    • Journal of Food Hygiene and Safety
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    • v.22 no.3
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    • pp.145-150
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    • 2007
  • Conjugated linoleic acid (CLA) reduces fat deposition in several mammalian species. The proposed mechanisms for this effect are reduced preadipocyte proliferation and differentiation. The objective of this study was to investigate the inhibitory effects of diglyceride (DG), CLA, DG-CLA of proliferation and differentiation of 3T3-L1 preadipocytes. Cell viability was determined using WST-8 analysis and cell differentiation was determined by glycerol-3-phosphate dehydrogenase (GPDH) activity. Lipid accumulation in differentiating 3T3-L1 cells was measured by Oil red O staining. The proliferation of preconfluent 3T3-L1 cells by treatments of DG, CLA, and DG-CLA was reduced in a dose-dependent manner. CLA among them was the most effective in reduction of viable cells with increasing concentrations. Treatments of the DG, CLA, and DG-CLA at the concentration of $100{\cdot}\ddot{I}g/ml$ for 48h significantly inhibited differentiation of 3T3-L1 cells (p<0.05). In addition. cytoplasmic lipid accumulation during differentiation of the 3T3-L1 preadipocytes was also inhibited by treatments of the test solutions. DG-CLA was the most effective in the inhibition of differentiation and lipid accumulation in 3T3-L1 cells. These results indicate that the DG including CLA as fatty acids is more effective for anti-obesity than DG or CLA alone and that consumption of DG-CLA as a dietary oil may give a benefit for controlling overweight in humans.

An Adaptive Reclosing Technique Considering the Distributed Generation (분산전원을 고려한 적응적 재폐로 기법)

  • Seo, Hun-Chul;Kim, Chul-Hwan;Yeo, Sang-Min
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.56 no.2
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    • pp.227-232
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    • 2007
  • The autoreclosing is applied to power system for maintaining system stability and continuity of supply. Developments on distributed generation(DG) grows significantly by environmental issues and economical issues. If the DG is connected to distribution system, the DG influences the technical aspects such as power quality, protection and stability. It causes the challenges to protection, especially to reclosing. In order to achieve reliability and safety of the distribution system, the rules and guidelines suggest that the DG units should be rapidly disconnected from the network before the reclosing. If the DG is disconnected whenever the fault occurs, it cannot be utilized effectively. This paper presents the adaptive reclosing algorithm considering the DG. The algorithm consists of angle oscillation's judgment, EEEAC(Emergency Expanded Equal-Area Criterion), calculation of optimal reclosing time and re-connection algorithm. The simulation is implemented for the DG technology by using EMTP MODELS. The simulation results show that the transient stability is maintained and the DG is protected against disturbance.