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Conformational Analysis of Catecholamines-Raman, High Resolution NMR, and Conformational Energy Calculation Study

  • Park Mi-Kyung;Yoo Hee-Soo;Kang Young Kee;Lee Nam-Soo;Ichiro Hanazaki
    • Bulletin of the Korean Chemical Society
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    • v.13 no.3
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    • pp.230-235
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    • 1992
  • The conformational analysis has been done for catecholamines (dopamine, norepinephrine, and epinephrine) in the cationic and di-anionic states. The species responsible for adsorption on silver metal surface is anionic deprotonated at hydroxyl groups of catechol moiety, i.e., di-anionic states of catecholamines. This was deduced from Fourier-transform Raman spectra of sodium salts of catecholamines. High resolution proton NMR (400 MHz) spectra of catecholamines in basic and neutral $D_2O$ solution show that the conformations of norepinephrine and epinephrine in the di-anionic states are preferred in gauche, but not for dopamine in the di-anionic state. However the energy difference between trans and gauche of catecholamines in the protonated cationic states is small enough to rotate freely through C-C bond in ethylamine moiety. The conformational calculations using an empirical potential function and the hydration shell model (a program CONBIO) show consistent with above experimental results. The calculations suggest that the species of catecholamines adsorbed on silver metal surface would be in favor of the gauche conformations.

Efficient power allocation algorithm in downlink cognitive radio networks

  • Abdulghafoor, Omar;Shaat, Musbah;Shayea, Ibraheem;Mahmood, Farhad E.;Nordin, Rosdiadee;Lwas, Ali Khadim
    • ETRI Journal
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    • v.44 no.3
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    • pp.400-412
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    • 2022
  • In cognitive radio networks (CRNs), the computational complexity of resource allocation algorithms is a significant problem that must be addressed. However, the high computational complexity of the optimal solution for tackling resource allocation in CRNs makes it inappropriate for use in practical applications. Therefore, this study proposes a power-based pricing algorithm (PPA) primarily to reduce the computational complexity in downlink CRN scenarios while restricting the interference to primary users to permissible levels. A two-stage approach reduces the computational complexity of the proposed mathematical model. Stage 1 assigns subcarriers to the CRN's users, while the utility function in Stage 2 incorporates a pricing method to provide a power algorithm with enhanced reliability. The PPA's performance is simulated and tested for orthogonal frequency-division multiplexing-based CRNs. The results confirm that the proposed algorithm's performance is close to that of the optimal algorithm, albeit with lower computational complexity of O(M log(M)).

GYAGG/6LiF composite scintillation screen for neutron detection

  • Fedorov, A.;Komendo, I.;Amelina, A.;Gordienko, E.;Gurinovich, V.;Guzov, V.;Dosovitskiy, G.;Kozhemyakin, V.;Kozlov, D.;Lopatik, A.;Mechinsky, V.;Retivov, V.;Smyslova, V.;Zharova, A.;Korzhik, M.
    • Nuclear Engineering and Technology
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    • v.54 no.3
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    • pp.1024-1029
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    • 2022
  • Composite scintillation screens on a base of Gd1.2Y1.8Ga2.5Al2.5O12:Ce (GYAGG) scintillator have been evaluated for neutron detection. Besides the powdered scintillator, the composite includes 6LiF particles; both are merged with a binder and deposited onto the light-reflecting aluminum substrate. Results obtained demonstrates that screens are suitable for use with a silicon photomultiplier readout to create a prospective solution for a compact and low-cost thermal neutron sensor. Composite GYAGG/6LiF scintillation screen shows a pretty matched sensitivity and γ-background rejection with a widely used ZnS/6LiF screens however, possesses forty times faster response.

PROTECTIVE EFFECT OF DA-3711, A NEW ANTIWRINKLE AGENT, AGAINST UVB-INDUCED SKIN DAMAGE IN HAIRLESS MICE MODEL

  • Kim, J. M.;Y. S. Sohn;K. K. Kang;Lee, E. D.;Lee, M. Y.;B. O. Ahn;Lee, J. H.;J. W. Kwon;Kim, W. B.
    • Proceedings of the SCSK Conference
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    • 2003.09a
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    • pp.698-699
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    • 2003
  • DA-3711 is a novel, anti wrinkle agent containing growth factors derived from human skin culture. In this study, effect of topical application of DA-3711 on chronic ultraviolet B (UVB)-induced skin damage was evaluated in hairless mice model. Exposure to UVB for 8 weeks induced apparent wrinkles on the back skin of the mice. The dorsal surfaces were exposed to UVB for a further 8 weeks, during which the surfaces where treated daily by topically application of a lotion containing either 35% or 70% of DA-3711. For comparison, lotion base, lotion base containing Cylasphere Retinol(equation omitted) (2500 I.U., Coletica) and NouriCe $l^{(R)}$ (Biozhem) were applied topically once a day for 8 weeks.(omitted))

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Growth and characterization of BON thin films prepared by low frequency RF plasma enhanced MOCVD method

  • Chen, G.C.;Lim, D.-C.;Lee, S.-B.;Hong, B.Y.;Kim, Y.J.;Boo, J.-H.
    • Journal of the Korean institute of surface engineering
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    • v.34 no.5
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    • pp.510-515
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    • 2001
  • It was first time that low frequency R.F. derived plasma enhanced MOCVD with frimethylborate precursor was used to fabricate a new ternary compound $BO_{x}$ $N_{y}$ . The formation of BON molecule was resulted from nitrogen nitrifying B-O, and forming the angular molecule structure proved by XPS and FT-IR results. The relationship between hardness and film thickness was studied. An thickness-independent hardness was fond about 10 GPa. The empirical calculation of band-gap and UV test result showed that our deposited $BO_{x}$ $N_{y}$ thin film was semiconductor material with 3.4eV of wide band gap. The electrical conductivity, $4.8$\times$10^{-2}$ /($\Omega$.cm)$^{-1}$ also confirmed that $BO_{x}$ $N_{y}$ has a semiconductor property. The roughness detected from the as-grown films showed that there was no serious bombarding effect due to anion in the plasma occurring in the RF frequency derived plasma.

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ENHANCED ADHESION STRENGTH OF Cu/polyimide AND Cu/Al/polyimide BY ION BEAM MIXING

  • Chang, G.S.;Kim, T.G.;Chae, K.H.;Whang, C.N.;Zatsepin, D.S.;Kurmaev, E.Z.;Choe, H.S.;Lee, Y.P.
    • Journal of the Korean Vacuum Society
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    • v.6 no.S1
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    • pp.122-126
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    • 1997
  • the Cu/polyimide system is known to be the best candidate for a multilevel interconnection system due to the low resistance of Cu and to the low dielectric constant of polyimide respectively. Ion beam mixing of Cu(40nm)/polyimide was carried out at room temperature with 80 keV Ar+ and N2+ form $1.5\times$1015 to 15$\times$1015 ions/cm2. The quantitative adhesion strength was measured by a standard scratch test. X-ray photoelectron spectroscopy and x-ray emission spectrocopy are employed to investigate the chemical bonds and the interlayer compound formation of the films Cu/Al/polyimide showed more adhesion strength than Cu/polyimide after ion beam mixing and N2+ ions are more effective in the adhesion enhancement than Ar+ with the same sample geometry. The XES results shows the formation of interlayer compound of CuAl2O4 which can reflect more adhesive Cu/Al/polyimide which has not been reported previously. The latter results is understood by the fact that N2+ ions produce more pyridinelike moiety, amide group and tertiary amine moiety whcih are known as adhesion promotors.

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Experimental and theoretical justification of passive heat removal system for irradiated fuel assemblies of the nuclear research reactor in a spent fuel pool

  • Ta Van Thuong;O.L. Tashlykov;S.M. Glukhov;D.E. Shumkov;Yu.V. Volchikhina
    • Nuclear Engineering and Technology
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    • v.55 no.6
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    • pp.2088-2095
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    • 2023
  • The safety of nuclear installations is largely determined by the tightness of fuel elements cladding. As the Fukushima nuclear accident showed, the main task in case of loss of power supply is to ensure reliable removal of residual heat release from spent fuel pool (SFP) with irradiated fuel assemblies (IFAs). The paper presents the results of calculated-experimental studies and thermal-hydraulic modeling of temperature storage modes of IFAs in SFP. Experimental studies of SFP's temperature regime and calculated evaluation of residual heat removal due to the thermal conductivity of building structures surrounding the SFP were performed. To ensure the safe operation of research reactors, it's necessary to know the IFA's residual heat power (RHP) in the reactor and SFP, which is determined depending on the operating time of fuel assemblies (FAs) and the IFAs calculated holding time. The FAs operating time depends on the reactor energy output. The IFAs calculated holding time is determined by the fuel burnup, U-235 mass in the fuel, and reactor utilization factor. The IFAs fuel burnup was calculated using the MCU-PTR program. Also presented are the RHP's calculation results using some of the empirical dependencies. The concept of a passive heat removal system (PHRS) based on thermosyphon's operating principle was proposed.

Analysis of Quality and Color Properties according to the Gas Composition (Modified Atmosphere Packaging) of Pork Sous-Vide Ham Preserved in Natural Brine

  • Sol-Hee Lee;Hack-Youn Kim
    • Food Science of Animal Resources
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    • v.43 no.4
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    • pp.580-593
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    • 2023
  • The purpose of this study was to analyze whether seawater has positive effects on appearance characteristics, such as CIE a*, and to determine the gas composition concentration that is suitable for maintaining it. Pork hind meat was cured with four types of curing agent for 5 d at 4℃. The different curing agents comprised the control salt, control nitrite pickling salt (CN), treatment brine, and treatment bittern (BT). The cured hams were cooked at 65℃ for 4 h and packaged at O2:N2 gas ratios of 7:3, 8:2, and 9:1 for 3 wk. The physicochemical properties were assessed immediately after heating the sample, and the color properties were measured after a 3 wk storage period. Based on the correlation results of the physicochemical properties, BT had a higher curing and cooking yield than the other treatments, owing to its high salinity. Results of color properties for BT (7:3) and CN (8:2) showed similar color CIE L*, CIE a* chroma, and hue angle values. Therefore, BT can be said to be a sous-vide curing agent suitable for preserving the color of ham, and a high nitrogen concentration of 30% helps to maintain the appearance of seawater sous-vide ham.

Issues of New Technological Trends in Nuclear Power Plant (NPPs) for Standardized Breakdown Structure

  • Gebremichael, Dagem D.;Lee, Yunsub;Jung, Youngsoo
    • International conference on construction engineering and project management
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    • 2020.12a
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    • pp.353-358
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    • 2020
  • Recent efforts to develop a common standard for nuclear power plants (NPPs) with the aim of creating (1) a digital environment for a better understanding of NPPs life-cycle management aspect and (2) engineering data interoperability by using existing standards among different unspecified project participants (e.g., owners/operators, engineers, contractors, equipment suppliers) during plants' life cycle process (EPC, O&M, and decommissioning). In order to meet this goal, there is a need for formulating a standardized high-level physical breakdown structure (PBS) for NPPs project management office (PMO). However, high-level PBS must be comprehensive enough and able to represent the different types of plants and the new trends of technologies in the industry. This has triggered the need for addressing the issues of the recent operational NPPs and future technologies' ramification for evaluating the changes in the NPPs physical components in terms of structure, system, and component (SSC) configuration. In this context, this ongoing study examines the recent conventional NPPs and technological trends in the development of future NPPs facilities. New reactor models regarding the overlap of variant issues of nuclear technology were explored. Finally, issues on PBS for project management are explored by the examination of the configuration of NPPs primary system. The primary systems' configuration of different reactor models is assessed in order to clarify the need for analyzing the new trends in nuclear technology and to formulate a common high-level PBS. Findings and implications are discussed for further studies.

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Fully parallel low-density parity-check code-based polar decoder architecture for 5G wireless communications

  • Dinesh Kumar Devadoss;Shantha Selvakumari Ramapackiam
    • ETRI Journal
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    • v.46 no.3
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    • pp.485-500
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    • 2024
  • A hardware architecture is presented to decode (N, K) polar codes based on a low-density parity-check code-like decoding method. By applying suitable pruning techniques to the dense graph of the polar code, the decoder architectures are optimized using fewer check nodes (CN) and variable nodes (VN). Pipelining is introduced in the CN and VN architectures, reducing the critical path delay. Latency is reduced further by a fully parallelized, single-stage architecture compared with the log N stages in the conventional belief propagation (BP) decoder. The designed decoder for short-to-intermediate code lengths was implemented using the Virtex-7 field-programmable gate array (FPGA). It achieved a throughput of 2.44 Gbps, which is four times and 1.4 times higher than those of the fast-simplified successive cancellation and combinational decoders, respectively. The proposed decoder for the (1024, 512) polar code yielded a negligible bit error rate of 10-4 at 2.7 Eb/No (dB). It converged faster than the BP decoding scheme on a dense parity-check matrix. Moreover, the proposed decoder is also implemented using the Xilinx ultra-scale FPGA and verified with the fifth generation new radio physical downlink control channel specification. The superior error-correcting performance and better hardware efficiency makes our decoder a suitable alternative to the successive cancellation list decoders used in 5G wireless communication.