• Clinical and Experimental Pediatrics
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• v.52 no.10
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• pp.1140-1146
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• 2009

Purpose:The pathophysiology of magnesium, the second highest common compound in humans, is still unclear, especially in preterm babies. We accessed the association between total magnesium (tMg), ionized Mg (iMg), and gestational age (GA) and that between serum magnesium (sMg) and intraventricular hemorrhage (IVH) in preterm babies. Methods:In all, 119 inborn preterm infants admitted between July 2006 and February 2008 were divided into the IVH group (19) and the control group (100) and were prospectively analyzed. TMg, iMg, pH, total calcium (tCa), and ionized Ca (iCa) levels were determined immediately after delivery or within 3 hours after birth, and their correlation with GA were investigated. Results:TMg was not correlated with GA, tCa, iCa, and pH. IMg was correlated with tMg (r=0.288, P=0.002) and iCa (r=0.212, P=0.021); however, it was not correlated with GA and pH. Mean GA and birth weight were significantly lower (P=0.002) and smaller (P=0.030) in the IVH group. Mean sMg was higher in the IVH group ($2.5{\pm}0.9mg/dL$) than in the control group ($2.1{\pm}0.6mg/dL$) (P=0.021). SMg was a risk factor even after logistic regression analysis (OR, 2.798; 95% C.I., 1.265-6.192; P=0.011). Conclusion:In less than 37-week-old preterm babies, tMg and iMg were similar, regardless of GA. High sMg may be a risk factor for IVH in premature babies, regardless of their exposure to antenatal magnesium.

• Journal of Periodontal and Implant Science
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• v.30 no.1
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• pp.39-52
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• 2000

Polypeptide growth factor belong to a class of potent biologic mediator which regulate cell differentiation, proliferation, migration and metabolism. 1,25-dihydroxyvitamin $D_3$ decrease cell proliferation, and stimulate alkaline phosphatase activity which express in osteoblast during cell differentiation period. IGF-I is known to stimulate cell proliferation and differentiation too. 1,25-dihydroxyvitamin $D_3$ is known to increase IGF-I binding sites and IGF binding protein which inhibite the effect of IGF. The purpose of this study is to evaluate potential role of IGF-I as mediator that control the action of 1,25-dihydroxyvitamin $D_3$. MC3T3-E1 cell were seeded $5{\times}10^5/ml$ at 100mm culture plate in ${\alpha}-MEM$ containing 10% fetal bovine serum. After 48 hour incubation period, medium were changed ${\alpha}-MEM$ containing 5% fetal bovine serum. After 24 hours, $10^{-9}M$ 1,25-dihydroxyvitamin $D_3$ added. Total mRNA was extracted at 0, 6, 24, 48, 72 hour. PRPCR method was programed for the detection of IGF-I mRNA. In the both groups of 1,25-dihydroxy vitamin $D_3$ treated and control, alternative splicing form of IGF-I, IGF-IA and IGF-IB were expressed. In the 1,25-dihydroxyvitamin $D_3$ treated group, IGF-I mRNA expression was matained until 24 hour, there after expression was decresed. MC3T3-E1 cell were seeded $2.5{\times}10^4/ml$ at 24well plate in ${\alpha}-MEM$ containing 10% fetal bovine serum. After 48 hour incubation period, medium were changed ${\alpha}-MEM$ containing 3% fetal bovine serum. After 24 hours, $10^{-9}M$ 1,25-dihydroxyvitamin $D_3$ and 10 ng/ml IGF-I were added separately or together. Cell were cultured for 1 and 3 days, $2{\mu}Ci/ml\;[^3H]$ -thymidine was added for the last 24h of culture of each days. ${[^3H]}$-thymidine incorporation in to DNA was measured and expressed counter per minute(CPM). DNA synthetic activity was significantly decreased by 1,25-dihydroxyvitamin $D_3$ both at 1 day and 3 day, and in the combination group of 1,25-dihydroxyvitamin $D_3$ and IGF-I, DNA synthetic activity was also decreased both at 1 day and 3 days. IGF-I did not affect the DNA synthetic activity compared to control group both at 1 day and 3 day. From the above results, 1,25-dihydroxyvitamin $D_3$ was potent inhibitor of cell proliferaton in MC3T3-E1 cells. It assumed that the effect of 1,25-dihydroxyvitamin $D_3$ on osteoblast proliferation may be mediated in part by decreased level of IGF-I.

• Journal of applied mathematics & informatics
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• v.3 no.2
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• pp.279-290
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• 1996

In the present paper we study the Cauchy problem in a Banach space E for an abstract nonlinear differential equation of form $$\frac{d^2u}{dt^2}=-A{\frac{du}{dt}}+B(t)u+f(t, W)$$ where W=($A_1$(t)u, A_2(t)u)..., A_{\nu}(t)u), A_{i}(t),\;i=1,2,...{\nu}$,(B(t), t{\in}I$=[0, b]) are families of closed operators defined on dense sets in E into E, f is a given abstract nonlinear function on $I{\times}E^{\nu}$ into E and -A is a closed linar operator defined on dense set in e into E which generates a semi-group. Further the existence and uniqueness of the solution of the considered Cauchy problem is studied for a wide class of the families ($A_{i}$(t), i =1.2...${\nu}$), (B(t), $t{\in}I$) An application and some properties are also given for the theory of partial diferential equations.

• Current Research on Agriculture and Life Sciences
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• v.4
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• pp.77-86
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• 1986

The purpose of this study is to estimate an optimum formula of rainfall intensity on basis of the characteristics for short period of rainfall duration in Kyungpook province for the design of urban sewerage and small basin drain system. Results studied are as follows; 1. The optimum method for Taegu and Pohang, Iwai's and Gumbel-Chow's method are recommended respectively. 2. The opotimum type of rainfall intensity for these area, $I=\frac{a}{\sqrt{t}+b}$ (Japanese type), is confirmed with 2.52~4.17 and 1.86~4.54 as a standard deviation for Taegu and Pohang respectively. The optimum formula of rainfall intensity are as follows. Taegu : T : 200 year - $I=\frac{824}{\sqrt{t}+1.5414}$ T : 100 year - $I=\frac{751}{\sqrt{t}+1.4902}$ T : 50 year - $I=\frac{678}{\sqrt{t}+1.4437}$ T : 30 year - $I=\frac{623}{\sqrt{t}+1.4017}$ T : 20 year - $I=\frac{580}{\sqrt{t}+1.3721}$ T : 10 year - $I=\frac{502}{\sqrt{t}+1.3145}$ T : 5 year - $I=\frac{418}{\sqrt{t}+1.2515}$ Pohang : T : 200 year - $I=\frac{468}{\sqrt{t}+1.1468}$ T : 100 year - $I=\frac{429}{\sqrt{t}+1.1605}$ T : 50 year - $I=\frac{391}{\sqrt{t}+1.1852}$ T : 30 year - $I=\frac{362}{\sqrt{t}+1.2033}$ T : 20 year - $I=\frac{339}{\sqrt{t}+1.2229}$ T : 10 year - $I=\frac{299}{\sqrt{t}+1.2578}$ T : 5 year - $I=\frac{257}{\sqrt{t}+1.3026}$ 3. Significant I.D.F. curves derived should be applied to estimate a suitable rainfall intensity and rainfall duration.

• Journal of the Korean Mathematical Society
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• v.44 no.4
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• pp.863-872
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• 2007

Let D be an integral domain with quotient field K, A a nonempty set of height-one maximal t-ideals of D, F$({\Lambda})={I{\subseteq}D|I$ is an ideal of D such that $I{\subseteq}P$ for all $P{\in}A}$, and $D_F({\Lambda})={x{\in}K|xA{\subseteq}D$ for some $A{\in}F({\Lambda})}$. In this paper, we prove that if each $P{\in}A$ is the radical of a finite type v-ideal (resp., a principal ideal), then $D_{F({\Lambda})}$ is a weakly Krull domain (resp., generalized weakly factorial domain) if and only if the intersection $D_{F({\Lambda})}={\cap}_{P{\in}A}D_P$ has finite character, if and only if $F({\Lambda})$ is a t-splitting set of ideals, if and only if $F({\Lambda})$ is v-finite.

• Journal of Oriental Medical Thermology
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• v.2 no.1
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• pp.11-16
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• 2003

Purpose D.I.T.I. can be used to diagnose the dysmenorrhea and prove the Oriental Medical Theory and the Sasang Constitutional Medicine concerning Dysmenorrhea. According to the Sasang Constitutional Medicine, we chose 39 dysmenorrhea patients (Soeumin 26 Patients, Taeumin 13 Patients) and expremented D.I.T.I. to find difference of chilliness and fever in the upper part of body and the lower part of body. Methods We expremented 39 dysmenorrhea patients chosena expremental group from Apr 1. 2002 to May 30, 2002. We diagnosed the constitution by Q.S.C.C. and selected six acu-points CV-17, CV-12, CV-4, G-21, B-15 and B-23. To appraise difference of temperature according to constitution we compared skin temperature of front to back. Result Mean Absolute Value of ${\Delta}T$ in body (front and back) shows significant difference. Totally the temperature of front is higher than the temperature of back. the temperature of Soeumin is higher than the temperature of Taeumin in whole. Conciusion Especially the upper abdomen area(CV-17) shows high temperature in 39 dysmenorrhea patients, the lower abdomen area (CV-4) of Soeumin shows lower temperature relatively.

• Journal of the Korean Mathematical Society
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• v.15 no.1
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• pp.59-61
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• 1978

Let $X_1$, $X_2$, ${\cdots}$, $X_n$ be i.i.d. uniform (0,1) random variables. Let $f_n(x)$ denote the probability density function (p.d.f.) of $T_n={\sum}^n_{i=1}X_i$. Consider a set S(x ; ${\delta}$) of lattice points defined by S(x ; ${\delta}$) = $x{\mid}x={\delta}+j$, j=0, 1, ${\cdots}$, n-1, $0{\leq}{\delta}{\leq}1$} The lattice distribution induced by the p.d.f. of $T_n$ is defined as follow: (1) $f_n^{(\delta)}(x)=\{f_n(x)\;if\;x{\in}S(x;{\delta})\\0\;otherwise.$. In this paper we show that $f_n{^{(\delta)}}(x)$ is a probability function thus we obtain a family of lattice distributions {$f_n{^{(\delta)}}(x)$ : $0{\leq}{\delta}{\leq}1$}, that the mean and variance of the lattice distributions are independent of ${\delta}$.

• The Journal of Internal Korean Medicine
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• v.21 no.1
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• pp.7-12
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• 2000

Objectives : This studies were performed to investigate the correlation between the treatment effects and the changes of the thermal differences at the pre and post-treatment by using the digital infrared computer thermographic imaging (D.I.T.I) to the irritable colon syndrome 30 patients. Methods : The extracts of the gwakhyangjunggisan were administerd to the patients by oral method three times per day during four weeks. we selected the Chung-Wan($CV_{12}$), Chunchu($S_{25}$). Hapkok($LI_4$), Naegwan($P_6$), Yongdo($H_4$) acupoints and treated the patients two times per week during four weeks. One week later, we investigated the changes of the pressure pain around left side Pokkyol($SP_{14}$), the symptoms. and the skin temperature changes on Pokkyol($SP_{14}$) and Kimun($LR_{14}$) around, by using the D.I.T.I. Results : In the correlation between the severity of the pressure pain around left side Pokkyol($SP_{14}$) and the thermal differences on Pokkyol($SP_{14}$) and Kimun($LR_{14}$) around, before the treatment, the more the pain was severe, the more the skin temperature was differential significantly. In the correlation between the severity of the symptoms and the thermal differences on Pokkyol($SP_{14}$) and Kimun($LR_{14}$) around, before the treatment, the more the symptom was severe, the more the skin temperature was differential significantly. In the changes of the pressure pain around left side of Pokkyol($SP_{14}$), the improved were significantly higher than the unimproved. In the changes of the symptoms, the improved were significantly higher than the unimproved. In the correlation between the changes of the pressure pain around left side Pokkyol($SP_{14}$) and the changes of the thermal differences at the pre and post- treatment, the more the pain was improved, the more the thermal change was widened significantly. In the correlation between the changes of the symptoms and the changes of thermal differences at the pre and post-treatment, the more the symptom was improved. the more the thermal change was widened significantly. Conclusions : Above the results, the treatments was effective and the digital infrared computer thermographic imaging (D.I.T.I) was useful to prove the improvements of the pressure pain and the symptom with the irritable bowel syndrome patients.

• Journal of Pharmacopuncture
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• v.6 no.1
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• pp.19-32
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• 2003

Objective : This study is perfonned for the purpose of examining the efficacy of the scolopendrid (Scolopendra morsitans L.) which has been used to low back pain as a folk remedy. Methods & Results : Seventy patients with H.I.V.D. treated with the scolopendrid aquacupuncture and examined 4 tests; D.I.T.L., physical test, Oswestry disability index, and self-conscious pain rate were studied. There was $50{\sim}100\%$ of efficacy rate in each tests. Moreover, statistically valuable change in 5 to 7 D.I.T.I. points and in self-conscious pain rate was showed. Conclusion : The scolopendrid aquacupuncture is possible to be effective treating the H.I.V.D patients. So we suggest the possibility using this new remedy to the H.I.V.D. patients.

• Proceedings of the Korean Magnestics Society Conference
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• 2008.12a
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• pp.78.2-78.2
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• 2008