• 대한기계학회:학술대회논문집
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• 대한기계학회 2000년도 추계학술대회논문집B
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• pp.192-198
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• 2000

Three dimensional thermal cycle analysis of the plunger is carried out in repeated forming process of the TV glass, which is continued work of two dimensional analysis where an efficient method has been proposed. The plunger undergoes temperature fluctuation during a cycle due to the repeated contact and separation from the glass, which attains a cyclic steady state having same temperature history at every cycle. Straightforward analysis of this problem brings about more than 90 cycles to get reasonable solution. An exponential function fitting method is proposed, which finds exponential function to best approximate temperature values of 3 consecutive cycles, and new cycle is restarted with the fitted value at infinite time. Number of cases are analyzed using the proposed method and compared to the result of straightforward repetition, from which one finds that the method always reaches nearly convergent solution within $9{\sim}12$ cycles, but turns around afterwards without further convergence. Two step use is found most efficient, in which the exponential fitting is carried out fer the first 12 cycles, followed by simple repetition, which shows fast convergence expending only 6 additional cycles to get the accuracy within 2 error. This reduces the computation cycle remarkably from 90 to 18, which is 80% reduction. From the parametric studies, one reveals that the overall thermal behavior of the plunger in terms of cooling parameters and time is similar to that of 2 dimensional analysis.

• The Korean Journal of Physiology and Pharmacology
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• 제16권3호
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• pp.153-158
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• 2012

Cellular effects of ethanol in YD-15 tongue carcinoma cells were assessed by MTT assay, caspase activity assay, Western blotting and flow cytometry. Ethanol inhibited the growth and proliferation of YD-15 cells in a dose- and time-dependent manner in an MTT assay. The effects of ethanol on cell cycle control at low percent range of ethanol concentration (0 to 1.5%), the condition not inducing YD-15 cell death, was investigated after exposing cells to alcohol for a certain period of time. Western blotting on the expression of cell cycle inhibitors showed that p21 and p27 was up-regulated as ethanol concentration increases from 0 to 1.5% whilst the cell cycle regulators, cdk1, cdk2, and cdk4 as well as Cyclin A, Cyclin B1 and Cyclin E1, were gradually down-regulated. Flow cytometric analysis of cell cycle distribution revealed that YD-15 cells exposed to 1.5% ethanol for 24 h was mainly arrested at G2/M phase. However, ethanol induced apoptosis in YD-15 cells exposed to 2.5% or higher percent of ethanol. The cleaved PARP, a marker of caspase-3 mediated apoptosis, and the activation of caspase-3 and -7 were detected by caspase activity assay or Western blotting. Our results suggest that ethanol elicits inhibitory effect on the growth and proliferation of YD-15 tongue carcinoma cells by mediating cell cycle arrest at G2/M at low concentration range and ultimately induces apoptosis under the condition of high concentration.

• Journal of Advanced Marine Engineering and Technology
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• 제32권8호
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• pp.1141-1148
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• 2008

One of the methods to increase the efficiency of an engine is to expand pressures obtained from combustions equal to the pressure of atmosphere as much as possible and then convert thermal energy into mechanical energy also as much as possible. In this research, the Diesel cycle was thermodynamically interpreted to evaluate the possibility of high efficiency by converting Diesel engines to the Atkinson cycle, and general cycle features were analyzed after comparing these two cycles. In the case of fuel air the Diesel-Atkinson cycle considering intake and exhaust similar to real cycles, the value of thermal efficiency and average effective pressure increased, though their values were smaller than those of standard air amount cycle, when expansion compression ratio increased. When normal Diesel engines of which compression stroke and expansion stroke are all the same, was converted to the Atkinson cycle by changing the time of intake value close, combustion pressure reduced due to reduced expansion compression ratio and intake air amount due to decreased effective cycle volume.

• 한국주조공학회지
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• 제30권1호
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• pp.46-51
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• 2010

Recently, automotive industry is attempting to replace steels for automotive parts with light-weight alloys such as aluminum alloy, because of the growing environmental regulations governing exhaust gas and the engine effectiveness of a vehicle. The low cycle fatigue (LCF) and high cycle fatigue (HCF) properties as well as the microstructure and tensile property were investigated on the low pressure cast A356 aluminum alloy wheel, which was followed by T6 heat treatment. The cast microstructure of the alloy influenced significantly on the low cycle and high cycle fatigue behaviors. The rim part of cast aluminum alloy wheel showed higher low cycle and high cycle fatigue strength compared with the spoke part, which should be caused by higher cooling rate of rim part. The spoke part of the wheel showed coarser dendrite arm spacing (DAS) and wide eutectic zone in the microstructure, which resulted in the partial brittle fracture and lower fatigue life time.

• 약학회지
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• 제58권1호
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• pp.33-39
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• 2014

The objective of this study is to evaluate the anticancer effects of the isoflavone extract from Chungkukjang in human breast cancer, MDA-MB-453 cells. For this study, MDA-MB-453 cells were treated with 12.5, 25, and $50{\mu}g$ isoflavone extract for 24, 48, and 72 hr. Cell proliferations were decreased in a time- and dose-dependent manner. Reduced cell proliferation was suspected by apoptosis or cell cycle arrest. Therefore, after treatment of $50{\mu}g$ isoflavone extract, apoptotic cells were investigated by annexin V staining. The results indicated that isoflavone extract increased the number of early apoptotic cells compared with control. Cleaved PARP was also increased. Next, we investigated the cell cycle and related proteins. The isoflavone extract leads to cell cycle arrest at the G2/M phase. Moreover isoflavone extract had influenced cell cycle relate proteins such as cyclin B1, cyclin A, and p21. These results suggest that isoflavone extract from Chungkukjang induce apoptosis and cell cycle arrest at G2/M phase via regulation of cell cycle-related proteins in MDA-MB-453 cells.

• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 2005년도 춘계학술대회 학술발표 논문집 제15권 제1호
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• pp.161-165
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• 2005

최적 교통 주기를 산출하기 위해서는 하위교차로에 대기차량이 얼마나 있는지를 점검해야 한다. 왜냐하면 대기차량이 상위교차로의 길이보다 크면 출발 지연 시간 및 승용차 대기시간이 발생하기 때문이다. 승용차 대기시간을 단축시키기 위해서 본 논문에서는 퍼지 신경망을 이용한 최적 연동 녹색시간 알고리즘을 제안한다. 컴퓨터 모의실험을 통해서, 서로 다른 교차로 조건을 고려하지 않은 고정 교통신호등 보다 평균 주행속도가 향상 된 것을 입증하였다.

• 대한가정학회지
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• 제34권5호
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• pp.49-66
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• 1996

The purpose of this study is to identify how the households invest in their children as a human capital. In addition, contributing factors to households' human capital investment was examined. The results of this study are as follows; First, Average number of children 2 children of surveyed housewives, full time housewives had more time spent for children than working counterparts. The former spent 6.8 hours a day with the latter 4.98 hour a day while both of them shared the most time in nonphysical care of their children. meanwhile, money paid for children was that full time housewife family spent 1,014,000 and a working housewife family paid 974,000. Second, In the full time housewives, total amount of time housewives spend for their children was greatly influenced by the income, the age of the youngest child, and emotional value. The housewives' educational level, life cycle, and an income were a significant impact on money investment. Total investment was influenced by the housewives' educational level, life cycle, income, and the number of children.

• 대한치매학회지
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• 제22권4호
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• pp.139-147
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• 2023

Background and Purpose: Dual walking task such as crossing over an obstacle may serve as an excellent tool for predicting early cognitive decline. Thus, this study aimed to investigate correlation between walking while crossing over an obstacle and executive functions under different gait phases to validate the use of walking with an obstacle for predicting early cognitive decline. Methods: A cross-sectional study was conducted on 48 elderly individuals from 2 day-care centers and 3 welfare-centers in Seoul and Gyeonggi, Korea. Executive function tests (Trail Making Test, Stroop test) and dual walking tests (gait speed, cadence, stance time, gait cycle time) were performed and compared using partial correlation analysis. Results: There were significant correlations between executive function and most of the gait variables (stance time, cadence, and gait cycle time) (p<0.05) when crossing over an obstacle while walking. Especially, stance time exhibited significant correlations with most executive functions (p<0.05). Conclusions: When evaluating executive function during walking with an obstacle, post-obstacle-crossing phase and stance time need to be observed.

• 한국터널지하공간학회 논문집
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• 제21권1호
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• pp.137-153
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• 2019

터널공사 시간 및 비용의 예측은 터널공사를 계획하는데 있어서 가장 기본적인 사항이며, 우리나라에서는 결정론적 방법에 따라 체계화된 표준품셈에 의해 계산하고 있다. 본 논문에서는 국내 터널 공사기간 또는 사이클타임의 신뢰성 있는 예측모델 구축이라는 장기적인 목표를 위하여, 우선 국내 터널 3개의 현장에 대한 터널굴착시간을 세부공종별로 분석하고, 터널설계시 공사기간을 추정하는 공식적인 방법인 표준품셈에서의 사이클타임과 비교하였다. 그 결과 실제 굴착 사이클타임은 표준품셈대비 3개의 터널 각각 50 %, 7%, 31% 수준의 차이를 보였고, 특히 숏크리트와 록볼트 타설시간에서는 각각 171%, 88%로 매우 큰 차이를 보였다. 이에 대한 가장 큰 이유는 표준품셈은 주된 작업공종별로만 작업시간이 분류되어 있어 터널작업자들의 숙련도, 각종 시공장비의 종류 및 사양, 또는 터널굴착작업에서 발생하는 다양한 시공조건을 고려하고 있지 않기 때문이다. 결국 본 연구결과는 현재까지 조사가 이루어진 터널 3개 현장의 특정한 상황에 대해서만 적용될 수 있으므로, 향후 터널굴착 세부작업시간에 대한 지속적인 데이터 축적을 통해 신뢰성 있는 터널굴진시간 예측모델을 구축할 계획이다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2013년도 춘계학술대회 논문집
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• pp.197-198
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• 2013