• Journal of Microbiology and Biotechnology
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• 제30권12호
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• pp.1810-1818
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• 2020

Inhibitor K562 (IK) protein was first isolated from the culture medium of K562 cells, a leukemia cell line, and is an inhibitory regulator of interferon-γ-induced major histocompatibility complex class II expression. Recently, exogenous truncated IK (tIK) protein showed potential as a therapeutic agent for inflammation-related diseases. In this study, we designed a novel putative anti-inflammatory peptide derived from tIK protein based on homology modeling of the human interleukin-10 (hIL-10) structure, and investigated whether the peptide exerted inhibitory effects against pro-inflammatory cytokines such as IL-17 and tumor necrosis factor-α (TNF-α). The peptide contains key residues involved in binding hIL-10 to the IL-10 receptor, and exerted strong inhibitory effects on IL-17 (43.8%) and TNF-α (50.7%). In addition, we used circular dichroism spectroscopy to confirm that the peptide is usually present in a random coil configuration in aqueous solution. In terms of toxicity, the peptide was found to be biologically safe. The mechanisms by which the short peptide derived from human tIK protein exerts inhibitory effects against IL-17 and TNF-α should be explored further. We also evaluated the feasibility of using this novel peptide in skincare products.

• Journal of Korea Multimedia Society
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• 제24권3호
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• pp.431-439
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• 2021

Since the sensor nodes are randomly arranged in the region of interest, it may happen that the sensor network area is separated or there is no sensor node in some area. In addition, after the sensor nodes are deployed in the sensor network, a coverage hole may occur due to the exhaustion of energy or physical destruction of the sensor nodes. The coverage hole can greatly affect the overall performance of the sensor network, such as reducing the data reliability of the sensor network, changing the network topology, disconnecting the data link, and worsening the transmission load. Therefore, sensor network coverage hole recovery has been studied. Existing coverage hole recovery studies present very complex geometric methods and procedures in the two-step process of finding a coverage hole and recovering a coverage hole. This study proposes a method for discovering and recovering a coverage hole in a sensor network, discovering that the sensor node is a boundary node by itself, and determining the location of a mobile node to be added. The proposed method is expected to have better efficiency in terms of complexity and message transmission compared to previous methods.

• Korean Medical Education Review
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• 제23권1호
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• pp.11-22
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• 2021

This review of the literature explored the experiences and effects of peer-assisted learning in basic medical education. Peer-assisted learning is most commonly utilized to teach clinical skills (including technical skills) and medical knowledge (76.4%). It has also been used, albeit less frequently, to facilitate small-group discussions including problem-based learning, to promote students' personal and professional development, to provide mentoring for career development and adaptation to school, to give tutoring to at-risk students, and to implement work-based learning in clinical settings. Near-peer learning is a common type. The use of active learning techniques and digital technology has been increasingly reported. Students' leadership had frequently been described. Student tutor training, programs for teaching skills, institutional support, and assessments have been conducted for effective peer-assisted learning. There is considerable positive evidence that peer-assisted learning is effective in teaching simple clinical skills and medical knowledge for tutees. However, its effects on complex skills and knowledge, small-group discussions, personal and professional development, peer mentoring, and work-based learning have rarely been studied. Additionally, little evidence exists regarding whether peer-assisted learning is effective for student tutors. Further research is needed to develop peer-assisted learning programs and to investigate their learning effects on student tutors, small-group discussion facilitation, personal and professional development, peer mentoring, and peer-led work-based learning in the clinical setting in South Korea. Formal programs and system advancement for a student-led learning culture is needed for effective peer-assisted learning.

• Computers and Concrete
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• 제30권3호
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• pp.197-207
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• 2022

Population growth in cities increases the need for service facilities and different urban spaces, and the organism of the city undergoes profound changes. One of the main problems that endanger the physical environment of the city due to this turmoil is the lack of public spaces and cultural complexes that increase individual and social pollution and on the other hand make leisure facilities available to the public. It severely limits people and, ultimately, the flourishing of individual and social artistic tastes. Thus, dealing with an issue called cultural complex has special importance and is one of the most basic categories in the field of architecture and urban planning, so dealing with it must be done in a measured, comprehensive and accurate manner. Cultural shock results from the immersion of an unprepared traveler in a foreign culture. In other words, human connection with people, objects, places, organizations and institutions, thoughts and the world of information will be constantly becoming more unstable and diverse. As a result, there is a need to create places for information or, in a central sense, to acquire up-to-date knowledge that requires information in the fields of human individual and social life. Spaces and places are all kinds of media tools from gramophone records to cassettes, CDs, newspapers, magazines, Internet books, etc. Each person can use them according to his needs and work.

• Korean Medical Education Review
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• 제24권3호
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• pp.193-204
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• 2022

One of the important roles of medical schools is to support medical students in deciding upon their future career path or choosing their specialty. The purpose of this study is to suggest a career advising model and strategies for medical students through a systematic approach. This study consists of three parts. The first part introduces some main career theories: super's career development theory, career decision-making theory, social cognitive career theory, and ecosystem theory. The second part proposes a systematic career advising model using the results acquired from previous studies and theories. This model considers a medical school as a social system that consists of two domains (internal and external). This social system is considered as a complex where various factors interact with each other: students' individual characteristics, institutional policies and culture, curriculum and learning experience, students' perceived specialty characteristics, and aspects of the external environment such as healthcare systems. The third part suggests some career advising strategies based on a systematic approach that medical schools can apply. These research results can be used for designing career advising courses for medical students, integrating various career advising programs and resources of medical schools, and evaluating the outcomes of career advising programs at an institutional level.

• Korean Journal of Occupational Health Nursing
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• 제30권4호
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• pp.224-231
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• 2021

Purpose: The purpose of this study was to identify the psychosocial working environment and mental health of financial workers, and analyze the impact of the former on the latter. Methods: Data of 257 financial clerks were extracted from the 2017 5th Korean Working Conditions Survey. Psychosocial working environment was divided into five fields: demands at work, work organizations, interpersonal relations, workplace violence, and working hour quality. Mental health included sleeping problems, psychological well-being, and job stress. Results: A total of 6.1% subjects reported sleep problems, 28.2% experienced poor psychological well-being, and 39.6% had job stress. More than half the subjects were exposed to tight deadlines, complex tasks, hiding feelings at work, fair treatment, fair distribution of work, colleagues' support, and managers' support. Tight deadlines, workplace violence, long working hours, hiding feelings at work, and managers' support had a significant impact on the mental health of financial clerks. Conclusion: Based on the results of this study, we propose that employers, workers, and health managers in the financial industry should work together to establish a respectful organizational culture, prevent long working hours through recruitment, and conduct programs to protect emotional health.

• The Korean Journal of Physiology and Pharmacology
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• 제26권5호
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• pp.297-305
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• 2022

The presence of artificial light enables humans to be active 24 h a day. Many people across the globe live in a social culture that encourages staying up late to meet the demands of various activities, such as work and school. Sleep deprivation (SD) is a severe health problem in modern society. Meanwhile, as with cardiometabolic disease, there was an obvious tendency that coronary heart disease (CHD) to become a global epidemic chronic disease. Specifically, SD can significantly increase the morbidity and mortality of CHD. However, the underlying mechanisms responsible for the effects of SD on CHD are multilayered and complex. Inflammatory response, lipid metabolism, oxidative stress, and endothelial function all contribute to cardiovascular lesions. In this review, the effects of SD on CHD development are summarized, and SD-related pathogenesis of coronary artery lesions is discussed. In general, early assessment of SD played a vital role in preventing the harmful consequences of CHD.

• Journal of the Semiconductor & Display Technology
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• 제22권1호
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• pp.104-112
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• 2023

Agriculture plays an industrial and economic role, as well as an environmental and ecological conservation role, group harmony and the inheritance of traditional culture. However, no matter how advanced the industry is, the basic food necessary for human life can only be produced through the photosynthesis of plants with natural resources such as the sun, water, and air. The Food and Agriculture Organization of the United Nations (FAO) predicts that the world's population will increase by another 2 billion people by 2050, and it faces a myriad of complex and diverse factors to consider, including climate change, food security concerns, and global ecosystems and political factors. In particular, in order to solve problems such as increasing productivity and production of agricultural products, improving quality, and saving energy, it is difficult to solve them with traditional farming methods. Recently, with the wind of the 4th industrial revolution, ICT convergence technology and artificial intelligence have been rapidly developing in many fields, but it is also true that the application of new technologies is somewhat delayed due to the unique characteristics of agriculture. However, in recent years, as ICT and artificial intelligence utilization technologies have been developed and applied by many researchers, a revolution is also taking place in agriculture. This paper summarizes the current state of research so far in four categories of agriculture, namely crop cultivation environment management, soil management, pest management, and irrigation management, and smart farm research data that has recently been actively developed around the world.

• Journal of the Korean Society of Clothing and Textiles
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• 제47권2호
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• pp.244-255
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• 2023

Patterns abstractly depicting flowing water with Chinese characters such as gong, wan(man), or wang continued endlessly and curved water patterns began appearing on textiles during the Song Dynasty. Though Song curved water patterns encompassed poetic sentiments such as "falling flowers and flowing water," the meaning faded with time, and these patterns were depicted in backgrounds with flowers added to brocade (Geum-sang-cheom-hwa). During the Ming and Qing Dynasties, combinations of diverse patterns, including flowers, butterflies, dragons, and auspicious treasures became fashionable, rather than the gong- and wan-shaped curved water patterns. Likewise, during the Joseon Dynasty, curved water patterns were preferred as background rather than as primary patterns. They were overlaid with flowers and clouds. The overlaid flower patterns included four-season flower patterns (17th-18th centuries), round flower patterns (19th century), and large flower patterns (20th century), which were identical to flower patterns fashionable at the time and arranged at intervals on complex curved water pattern backgrounds. In contrast, simple Ruyi types were more numerous than the four-Ruyi types fashionable at the time with regard to cloud patterns. Added here were Taiji (great ultimate symbol) or crane patterns, thus seeking to depict diverse auspicious Ruyi such as wish fulfillment and longevity.

• East Asian Journal of Business Economics (EAJBE)
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• 제11권3호
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• pp.27-35
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• 2023

Purpose - The present study bridges a significant gap in the literature by investigating the complex relationship between job crafting and protean career attitudes. It has been demonstrated that job crafting, which entails the proactive redesign of work roles, responsibilities, and relationships, empowers employees, and elevates. Research design, data, and methodology - This study employed a tailored search approach with specific terms linked to job crafting and protean career attitudes to ensure a thorough and focused analysis. The keywords include "Job crafting," "protean career attitudes," "career development," and related terms. This strategy uses an organized method to identify, screen, and choose appropriate studies. Result: This study synthesizes prior studies and identifies four critical links between the development of jobs and protean career attitudes. To begin with, task crafting, which entails job requirements and scope modifications, leads to protean career attitudes as employees match their roles to their skills and passions. Second, rational crafting, which is adjusting interactions with coworkers and superiors encourages flexible career attitudes. Conclusion - This study insists that organizations must consider the essential practical ramifications. Employers may improve employee growth, engagement, and talent retention by encouraging job customization, recognizing protean workers, cultivating a protean culture, investing in ongoing learning.