• The Journal of the Convergence on Culture Technology
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• v.8 no.6
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• pp.121-126
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• 2022

This study analyzed the survival rate of commercial districts before and after the outbreak of COVID-19 by analyzing Gangnam-gu, Seoul and Suseong-gu, Daegu as independent regions, although the background and distribution of commercial districts are similar. In the basic analysis, the size of the commercial districts was much larger in Gangnam-gu, Seoul, but it was confirmed that the distribution by industry was similar. In both regions, there were more openings than closings before the outbreak of COVID-19 in common, but as the COVID-19 outbreak occurred, the closure ratio of businesses centered on face-to-face services increased significantly. As a result of the survival analysis, it was analyzed that most industries were indifferent to the risk of closure of private institutes before Corona 19, but after the outbreak of Corona 19, it was confirmed that the risk of closure of private institutes increased, especially in Daegu, which was the initial spread of Corona 19. As a result of comparing the survival rate between regions, it was analyzed that the risk of business closure in Gangnam-gu increased relatively after the outbreak of Corona 19, confirming that the contraction in the commercial area of Seoul with a large floating population was greater.

• The Journal of the Convergence on Culture Technology
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• v.8 no.6
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• pp.935-941
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• 2022

The purpose of this study was to investigate whether the activity of ginsenoside metabolites and the intestinal immunity antioxidant activity were remarkably improved by lactic acid bacteria fermentation by adding a small amount of ginsenoside to the complex extracts of fruits and vegetables. It was confirmed that the increase in intestinal immunity antioxidant activity due to synergistic effect was observed in the fruit-vegetable extract containing ginsenoside compared to the ginsenoside-only extract or the fruit-vegetable extract. Then, by adding ginsenosides by content, the concentration of ginsenosides that can obtain a synergistic effect according to the fermentation of lactic acid bacteria was determined. As a result, it was confirmed that a synergistic effect was exhibited when lactic acid bacteria were fermented and extracted by mixing ginsenosides in a mass ratio of 3 to 10% with respect to the mass of the fruit-vegetable mixture. As a result, when treated at a concentration of 200 ㎍/ml, the fruit-vegetable complex extract containing ginsenoside metabolites inhibited the generation of NO by about 60% compared to the complex extract containing no ginsenoside, The expression of IL-1β was suppressed by 63%, the expression of IL-6 by 69%, and the expression of TNF-α by 76%, confirming that the intestinal immune antioxidant properties were significantly improved.

• The Journal of the Convergence on Culture Technology
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• v.8 no.5
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• pp.697-703
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• 2022

Due to the recent economic downturn caused by Covid-19 and the unstable international situation, many investors are choosing the derivatives market as a means of investment. However, the derivatives market has a greater risk than the stock market, and research on the market of market participants is insufficient. Recently, with the development of artificial intelligence, machine learning has been widely used in the derivatives market. In this paper, reinforcement learning, one of the machine learning techniques, is applied to analyze the scalping technique that trades futures in minutes. The data set consists of 21 attributes using the closing price, moving average line, and Bollinger band indicators of 1 minute and 3 minute data for 6 months by selecting 4 products among futures products traded at trading firm. In the experiment, DNN artificial neural network model and three reinforcement learning algorithms, namely, DQN (Deep Q-Network), A2C (Advantage Actor Critic), and A3C (Asynchronous A2C) were used, and they were trained and verified through learning data set and test data set. For scalping, the agent chooses one of the actions of buying and selling, and the ratio of the portfolio value according to the action result is rewarded. Experiment results show that the energy sector products such as Heating Oil and Crude Oil yield relatively high cumulative returns compared to the index sector products such as Mini Russell 2000 and Hang Seng Index.

• The Journal of the Convergence on Culture Technology
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• v.8 no.5
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• pp.713-721
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• 2022

In order to use the LED video wall in the broadcasting studio, there are a few things to be aware of. First, since the pixels are closely arranged, a moire phenomenon may occur due to a short arrangement period, and second, the distance between pixels (pixel pitch) may be recorded on the image sensor of the broadcasting camera. When moire occurs or pixel pitch is observed, viewers feel uncomfortable. Moire effect can be reduced by adjusting the shooting distance or angle of the camera, but in order to prevent the pixel pitch from being recorded on the image sensor, secure a sufficient distance between the LED video wall and camera. even when the distance secured, the zoom lens used in the broadcasting studio must be operated by appropriately changing the magnification. If the focal length is changed by changing the magnification to obtain a desired angle of view, the pixel pitch may be unintentionally recorded. In this study we propose the range that the pixel pitch is not observed while changing the magnification ratio of the zoom lens when the distance from the video wall is sufficiently secured. The content was played back on the LED video wall and the LED video wall was recorded on the server using an HD camera equipped with a B4 mount zoom lens

• Journal of Industrial Convergence
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• v.20 no.11
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• pp.85-93
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• 2022

As of the end of 2019, the total population nationwide was 51,849,861, and over the past five years, the population per household has decreased by 1.52% annually from 2.45 in 2015 to 2.31 in 2019. Looking at the current status of population distribution by age group, Busan metropolitan city had the highest proportion of senior citizens aged 65 or older at 18.2%, and Sejong Special Self-Governing city had the lowest at 9.4%. In particular, as of 2019, the population of the mobility handicapped was 15,219,000 nationwide, showing a ratio of about 29.4% of the total population. Therefore, it is important to secure the right to move according to the mobile facilities so that the mobility handicapped can move safely and conveniently. Against this background, this study places value on transportation welfare facilities centered on the mobility handicapped for safe and convenient movement, and in particular, in proposing measures to cope with the entry of an aging society and the continuous increase of the mobility handicapped, the transportation facilities, The purpose of this study is to analyze the impact of welfare facilities on the mobility handicapped and suggest implications. As a research method, the results of statistical analysis methods were presented through major preceding studies and expert surveys.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.8 no.2
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• pp.53-61
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• 2022

This study aimed to increase the targeting ability against PSMA in cell therapy using metabolic glycoengineering and biorthogonal chemistry and to visualize cell trafficking using PET imaging. Cellular membranes of THP-1 cells were decorated with azide(-N₃) using Ac₄ManNAz by metabolic glycoengineering. Engineered THP-1 cells were conjugated with DBCO-bearing fluorophore (ADIBO-Cy5.5) for 1 h at different concentrations and analyzed by confocal fluorescence microscopy and flow cytometry. For PSAM ligand conjugation to THP-1 cells, Ac₄ManNAz treated THP-1 cells were incubated with DBCO-PSMA ligand (ADIBO-GUL) at a final concentration with 100 µM for 1 h. To evaluate the effect on cell recognition, PSMA ligand conjugated THP-1 cells(as effectors) were co-cultured with PSMA positive 22RV1 (as target cells) at 3 : 1 a effector-to-target cell (E/T) ratio. The interaction between THP-1 and 22RV1 was monitored by confocal fluorescence microscopy. For preparing the radiolabeled THP-1, the cells were treated at the activity of ~ 740 kBq of [⁸⁹Zr]Zr(oxinate)₄/5 × 10⁶ cells. Radiolabeled cells were analyzed for determination of cell-associated radioactivity by gamma counting and viability using MTS assay. In the cytotoxicity assay, THP-1 cells did not have any cytotoxicity even when the Ac₄ManNAz concentration was 100 µM. In confocal microscopy and flow cytometry, THP-1 cells were efficiently labeled ADIBO-Cy5.5 in a dose-dependent manner, and the dose of 100 µM was the optimal concentration for the following experiments. The clusters of PSMA ligand-conjugated THP-1 cells and 22RV1 cells were identified, indicating cell-cell recognition over the cell surface between two types of cells. Cell radiolabeling efficiency was 54.5 ± 17.8%. THP-1 labeled with 0.09 ± 0.03 Bq/cell showed no significant cytotoxicity compared to unlabeled THP-1 up to 7 days. We successfully demonstrated that Ac₄ManNAz treated cells were efficiently conjugated with ADIBO-GUL for preparing the PSMA-targeting cells, and [⁸⁹Zr]Zr(oxinate)₄ could be used to label cells without toxicity. It suggested that PSMA-ligand conjugated cell therapy could be improved cell targeting and be monitored by PET imaging.

• Health Policy and Management
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• v.33 no.3
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• pp.243-252
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• 2023

This paper aims to introduce Korea's total current health expenditure (CHE) and National Health Accounts of the year 2021 and their 2022 preliminary figures constructed on the basis of the System of Health Accounts 2011. As CHE includes expenditures for prevention, tracking, and treatment of coronavirus disease 2019 (COVID-19) and compensation for losses to medical institutions from 2020, the details are also introduced. Korea's total CHE in 2021 is 193.3 trillion won, which is 9.3% of gross domestic product (GDP). The preliminary figure in 2022, 209.0 trillion won, exceeded the 200 trillion won line for the first time, and its "ratio to GDP" of 9.7% is expected to exceed the average of Organisation for Economic Co-Operation and Development member countries for the first time. Korea's health expenditures, which were well controlled until the end of the 20th century, have increased at an alarming rate since the beginning of the 21st century, threatening the sustainability of national health insurance. The increase in health expenditure after 2020 is partly due to a temporary increase in response to COVID-19. However, when considering the structure of Korea's health insurance price hike, where the ratchet effect of increased medical expenses works particularly strongly, it is unlikely that the accelerating growth trend that has lasted for more than 20 years will stop easily. More aggressive policies to control medical expenses are required in the national health insurance which not only constitutes the main financing sources of the Korean health system but also has the most powerful policy means in effect for changes in the health care provision.

• The Journal of the Convergence on Culture Technology
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• v.9 no.1
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• pp.19-26
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• 2023

In this study, the public sensitivity of the 'MZ generation' was examined through the social media big data sensitivity analysis method. For the analysis, the consumer account SNS text was examined, and positive and negative emotional factors were presented by classifying external sensibilities and emotions of the MZ generation. In conclusion, the positive emotions of liking and interest in relation to the "MZ generation" were 72.1%, higher than the negative emotional ratio of 27.9%. In positive sensitivity, the older generation showed 'a favorable feeling for the individuality and dignifiedness of the MZ generation' and 'interest in the MZ generation with new values'. In contrast, the MZ generation has a favorable feeling for 'the fact that they are a generation of their own boldness, youthfulness and individuality' and 'small growthism'. Negative sensitivity outside the MZ generation was found to be 'A concern about the marriage avoidance, employment difficulties, debt investment, and resignation trends of the MZ generation', 'Hate the MZ generation who treats Kkondae' and 'Difficult to talk to the MZ generation'. On the other hand, the negative emotions felt by the MZ generation itself were 'Rejection of generalization', 'Rejection of generation and gender conflicts', 'Rejection of competition worse than the older generation', 'Relative failure of the rich era', and 'Sadness to live in a predicted climate disaster'. Therefore, the older generation should not look at the MZ generation in general, but as individuals, and should alleviate conflicts with intergenerational understanding and empathy. there is a need for community consideration to solve generational conflicts, gender conflicts, and environmental problems.

• Journal of Industrial Convergence
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• v.21 no.5
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• pp.77-85
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• 2023

Suicide is the leading cause of death among Korean adolescents. There is a growing interest in the role of loneliness as a risk factor for suicide ideation and depressive symptoms. However, little is known in the Korean context. This study analyzed a total of 109,796 respondents from the Korea Youth Health Behavior Survey in 2020 and 2021. Multiple logistic regression models were implemented to test the association between loneliness and either of suicidal ideation and depressive mood. Covariates included demographic characteristics, school enrolled, household income, living arrangement, self-rated health, and the number of times treated for violence. Adjusted odd ratio (OR) and 95% confidence intervals (CI) were computed. 12.0% of adolescents reported to have felt lonely frequently and 3.0% always. 11.8% and 26.0% had suicidal ideation and depressive mood, respectively. The prevalence of suicidal ideation was higher in the always-lonely adolescents (52.6%) than in the frequently-lonely adolescents (35.1%). The always-lonely adolescents were nearly 30 times more likely to have suicidal ideation (OR=30.7; 95% CI, 27.1 - 34.8) and to feel depressed (OR=32.5; 95% CI, 29.2 - 36.4) than adolescents who felt never lonely. In conclusion, Loneliness was a major risk factor for suicidal ideation and depressive mood among Korean adolescents. Monitoring and addressing the condition of loneliness may help reduce suicidal ideation and depressive mood.

• The Journal of the Acoustical Society of Korea
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• v.41 no.6
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• pp.610-620
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• 2022

An acoustic vector sensor can simultaneously receive vector quantities, such as particle velocity and acceleration, as well as acoustic pressure at one location, and thus it can be used as a single input multiple output receiver in underwater acoustic communication systems. On the other hand, vector signals received by a single vector sensor have different channel characteristics due to the azimuth angle between the source and receiver and the difference in propagation angle of multipath in each component, producing different communication performances. In this paper, we propose a channel parameter-based weighting method to improve the performance of an acoustic communication system using a single vector sensor. To verify the proposed method, we used communication data collected from the experiment conducted during the KOREX-17 (Korea Reverberation Experiment). For communication demodulation, block-based time reversal technique which is robust against time-varying channels were utilized. Finally, the communication results showed that the effectiveness of the channel parameter-based weighting method for the underwater communication system using a single vector sensor was verified.