• Journal of Korean Medical classics
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• v.29 no.2
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• pp.165-176
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• 2016

Objectives : This study was done to investigate the formation process of the 'The Spleen controls the blood(脾統血)' concept, to clarify what this concept means and the mechanism of its physiology. Methods : Contents including 'Controlling blood(統血)' and 'Binding blood(攝血)' were searched and analyzed in medical classics. Previous researches were applied. Results & Conclusions : The concept of 'Controlling blood' could be defined as the control of blood movement. This means that it sends blood to where it's needed, and inhibits flow from where it's excessive. 'The Spleen controls the blood' was not used as a physiologic term in early books like Huangdineijing(黃帝內經). It was first used in the 13C, then widely after the 16C. The mechanism of 'Controlling blood' could be classified as the function of 'Production', 'Distribution', and 'Adjustment' of blood. 'Production' of blood can reduce blood fever(血熱) and blood stasis(瘀血), and prevent bleeding. 'Distribution' of blood can reduce the symptoms raised by lack of blood in the five viscera and body. 'Adjustment' of blood means maintaining homeostasis and stability of the human body. Pi can adjust blood flow and prevent blood from being imbalanced.

• Nutrition Research and Practice
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• v.1 no.3
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• pp.237-242
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• 2007

The purpose of this study was to compare food intakes between Korean breast cancer patients and a healthy control group. We compared the intake of nutrients of 117 food items between Korean breast cancer patients (n=97) and age matched healthy controls (n=97). Nutrient intake was estimated using a quantitative food frequency questionnaire. The mean caloric intake of breast cancer patients and healthy controls was not significantly different. Breast cancer patients consumed significantly less fat and antioxidant nutrients such as vitamin A, retinol, ${\beta}-carotene$, vitamin C and vitamin E when compared to the control subjects. Among the food items, the intake of eggs (p<0.01), legumes (p<0.05), vegetables (p<0.05), seasonings (p<0.001), and oils and fats (p<0.01) in breast cancer patients was significantly lower than that in the controls. These results suggest that Korean breast cancer patients consumed less amount of soy and vegetables, which are rich source of antioxidant nutrients and phytosterols. Thus, dietary guidance to increase intake of these foods may be beneficial in the prevention of breast cancer.

• The Journal of Korean Physical Therapy
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• v.21 no.2
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• pp.71-77
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• 2009

Purpose: This study assessed the differences in the forward head posture (FHP), cervical range of motion, and headache clinical parameters in episodic tension-type headache (ETTH) subjects, chronic tension-type headache (CTTH) subjects, and healthy controls (university students). Methods: Fifteen CTTH subjects, 15 ETTH subjects and 15 controls without headache were examined. Side-view images of each group were taken in both the sitting and standing positions, in order to assess the FHP by measuring the craniovertebral angle. The CROM was used to measure the cervical range of motion. A headache diary was kept for 4 weeks to assess the headache intensity, frequency, and duration. Results: The craniovertebral angle was smaller, ie, there was a greater FHP, in the CTTH and ETTH subjects than in the healthy controls in both the sitting and standing positions (p<0.05). The CTTH and ETTH subjects showed a lower cervical range of motion than the healthy controls in the total range of motion as well as in the half-cycles (p<0.05). Conclusion: The increased FHP and decreased cervical range of motion might be a contributing factor in the initiation of tension-type headache.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.9
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• pp.4588-4608
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• 2017

The measurement of information security levels is a very important but difficult task. So far, various measurement methods have studied the development of new indices. Note, however, that researches have focused on the problem of attaining a certain level but largely neglecting research focused on the issue of how different types of possible flaws in security controls affect each other and which flaws are more critical because of these effects. Furthermore, applying the same weight across the board to these flaws has made it difficult to identify the relative importance. In this paper, the interrelationships among security flaws that occurred in the security controls of K-ISMS were analyzed, and the relative impact of each security control was measured. Additionally, a case-control study was applied using empirical data to eliminate subjective bias as a shortcoming of expert surveys and comparative studies. The security controls were divided into 2 groups depending on whether or not a security flaw occurs. The experimental results show the impact relationship and the severity among security flaws. We expect these results to be applied as good reference indices when making decisions on the removal of security flaws in an enterprise.

• Genomics & Informatics
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• v.17 no.3
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• pp.29.1-29.8
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• 2019

The Wellcome Trust Case Control Consortium (WTCCC) study was a large genome-wide association study that aimed to identify common variants associated with seven diseases. That study combined two control datasets (58C and UK Blood Services) as shared controls. Prior to using the combined controls, the WTCCC performed analyses to show that the genomic content of the control datasets was not significantly different. Recently, the analysis of human leukocyte antigen (HLA) genes has become prevalent due to the development of HLA imputation technology. In this project, we extended the between-control homogeneity analysis of the WTCCC to HLA. We imputed HLA information in the WTCCC control dataset and showed that the HLA content was not significantly different between the two control datasets, suggesting that the combined controls can be used as controls for HLA fine-mapping analysis based on HLA imputation.

• KIEAE Journal
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• v.14 no.3
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• pp.71-77
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• 2014

This study aimed at developing and evaluating performance of the two logics for respectively operating two-position- and variable-heating systems. Both logics control the heating system and openings of the double skin facade buildings in an integrated manner. Artificial neural network models were applied for the predictive and adaptive controls in order to optimally condition the indoor thermal environment. Numerical computer simulation methods using the MATLAB (Matrix Laboratory) and TRNSYS (Transient Systems Simulation) were employed for the performance tests of the logics in the test module. Analysis on the test results revealed that the variable control logic provided more comfortable and stable temperature conditions with the increased comfortable period and the decreased standard deviation from the center of the comfortable range. In addition, the amount of heat supply to the indoor space was significantly reduced by the variable control logic. Thus, it can be concluded that the optimal control method using the artificial neural network model can work more effectively when it is applied to the variable heating systems.

• Geomechanics and Engineering
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• v.10 no.3
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• pp.325-334
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• 2016

Rock salt is a near-perfect material for gas storage repositories due to its excellent ductility and low permeability. Gas storage in rock salt layers during gas injection and gas production causes the stress redistribution surrounding the cavity. The triaxial cyclic loading and unloading tests for rock salt were performed in this paper. The elastic-plastic deformation behaviour of rock salt under cyclic loading was observed. Rock salt experienced strain hardening during the initial loading, and the irreversible deformation was large under low stress station, meanwhile the residual stress became larger along with the increase of deviatoric stress. Confining pressure had a significant effect on the unloading modulus for the variation of mechanical parameters. Based on the theory of elastic-plastic damage mechanics, the evolution of damage during cyclic loading and unloading under various confining pressure was described.

• Journal of Fisheries and Marine Sciences Education
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• v.16 no.1
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• pp.84-98
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• 2004

Due to a publicly owned resources, the overexploitation of the fisheries resources can result in externalities in the form of reduced future levels of yield. These problems can be theoretically improved through effective management of the fishery. The paper illustrates maximum sustainable yield(MSY), maximum economic yield(MEY) and F0.1 level of fishing mortality as the concept of optimal yield, and it theoretically shows that MSY is more appropriate for the optimal yield than MEY where prices increase even though MEY achieves the maximization of economic rent in a fishery assuming constant prices. And the paper presents several fisheries management tools and policies such as input controls, output controls and taxes. As the traditional approach to fishery management, input controls involve restrictions on the physical inputs into the production process(e.g. capital, time or technology) and output controls involve limits on the quantity of fish that can be landed. To introduce user cost into the harvest decisions of rent-seeking fishers, taxation, as a bioeconomic management policy of the fisheries, directly addresses the problems associated with the resource being unpriced. As most fisheries management plans, however, have increasing fisher income as an objective, taxes have not been introduced into any fisheries management policies despite their theoretical attraction.

• BMB Reports
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• v.37 no.2
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• pp.234-238
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• 2004

This study was designed to investigate, in the Turkish population, the association of methylene tetrahydrofolate reductase (MTHFR) C677T polymorphism and left ventricular hypertrophy (LVH) in patients with type II diabetes mellitus. Our study included 249 patients with type II diabetes mellitus (102 men, 147 women) and 214 healthy volunteers as controls (91 men, 123 women). MTHFR C677T genotypes were determined by polymerase chain reaction, restriction fragment length polymorphism techniques. No differences were observed in the distribution of MTHFR genotypes or allele frequencies in the cases versus the controls. The frequency of the MTHFR-mutated allele (T) was 31.7% in the type II diabetes mellitus versus 31.1% of the controls. The homozygous mutation (T/T) in the MTHFR gene was identified in 12% of the type II diabetes mellitus versus 9.3% of the controls. Patients with the TT genotype showed a higher prevalence of LVH when compared to patients with the CC and CT genotypes (p = 0.01). The MTHFR gene C677T mutation may be a possible risk factor for the development of LVH in the type II diabetic patients.

• Journal of the Korean Dietetic Association
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• v.5 no.2
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• pp.145-152
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• 1999

This study was to investigate the risk factors for the development of diabetes mellitus on healthy offsprings of Korea non-insulin dependent diabetes mellitus(NIDDM) patients. Forty four offsprings who have at least 1 parent with NIDDM and age, sex and body mass index(BMI) matched forty four healthy control subjects were collected for this study. BMI, skinfold thickness, waist/hip circumference ratio(WHR), fasting blood glucose, serum insulin, serum lipid profile, nutrient intakes and food behaviors were measured. There were no significant difference in BMI, WHR, fasting blood glucose, insulin, total cholesterol, triglyceride and daily nutrients intake between offsprings and controls. But skinfold thickness, LDL-cholesterol level and sweety food eating frequency were significantly higher in male offsprings than in male controls. And HDL-cholesterol was significantly lower in male offsprings than in male controls. Although there were no significant difference, offsprings had a overeating habit and ate more confectionery and greasy food than controls.