• 대한한방내과학회지
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• 제16권1호
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• pp.181-196
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• 1995

The present experiments were designed to investigate the effects of BangPoongSan on the cardiovascular system in the experimental Animals. And thus the change of blood pressure, auricular blood flow, artery contraction, death rate, platelet aggregation repression, plasma coagulation factor activity, plasma antithrombin activity, whole blood viscosity and plasma viscosity were studied. The result were summarized as the followings: 1. BangPoongSan dropped the blood pressure in the spontaneous hypertensive rat. 2. The drug increased the auricular blood flow in rabbit. 3. The drug relaxed the artery contraction by pretreated norepinephrine in white rat. 4. The drug inhibited the death rate of mouse which was led to thromboembolism by serotonin and collagen. 5. The drug inhibited the platelet aggregation in rat. 6. The drug prolonged the prothrombin time and activated partial thromboplastin time on the test of plasma coagulation factor activity in rat, but was not valuable. 7. The drug presented the antithrombin activity in rat. 8. The drug reduced the whole blood viscosity and plasma viscosity in rat, but the latter was not valuable. According to the results, Bangpoongsan increased the blood flow and dropped the blood pressure by dilatation of blood vessel smooth muscle. And the drug presented the antithrombin acivity, inhibited the platelet aggregation and reduced blood viscosity. Therefore these effects are assumed to improve the cardiovascular circulation disorder and prevent thrombosis.

• 대한기계학회논문집B
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• 제25권12호
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• pp.1844-1852
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• 2001

Recent developments in microfluidic devices based on microelectromechanical systems (MEMS) technique find many practical applications, which include electronic chip cooling devices, power MEMS devices, micro sensors, and bio-medical devices among others. For the design of such micro devices, flows characteristics inside a microchannel have to be clarified which exhibit somewhat different characteristics compared to conventional flows in a macrochannel. In the present study microchannels of various hydraulic diameters are fabricated on a silicon wafer to study the pressure drop characteristics. The effect of abrupt contraction and expansion is also studied. It is found from the results that the friction factor in a straight microchannel is about 15% higher than that in a conventional macrochannel, and the loss coefficients in abrupt expansion and contraction are about 10% higher than that obtained through conventional flow analysis.

• 분석과학
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• 제11권3호
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• pp.202-205
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• 1998

X선 흡수 미세구조 분석 기술을 이용하여 Ni-Zn 도금 강판에서의 Ni 주위 국부구조를 연구하였다. 실험적으로 측정한 X선 흡수 미세구조 스펙트럼과 이론적인 스펙트럼을 비교 분석함으로서 Ni-Zn 원자간 거리와 Debye-Waller factor를 결정하였는데 이때 측정 온도의 범위는 80K로부터 300K까지이었다. 이 측정 온도 범위내에서는 Ni-Zn 원자간 거리의 온도에 따른 변화는 매우 작았으며 원자간 거리의 평균값은 $2.557{\AA}$이었다. 그리고 이러한 Ni-Zn 원자간 거리의 값을 순수한 Zn 금속 재료의 가장 가까운 이웃 원자간 거리의 값과 비교하여 볼 때 Ni-Zn 전기 도금층의 Ni 원자 주위에 약간의 contraction이 있는 것을 알 수 있었다. 한편, Debye-Waller factor는 온도에 따라 0.005~0.011 정도의 값을 가지며 비교적 큰 온도 의존도를 가지는 것으로 나타났다.

• 대한산업공학회지
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• 제29권2호
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• pp.145-149
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• 2003

We consider the estimation of failure rate and acceleration factor under type-I censoring without using acceleration model when testing is conducted in only one highly accelerated condition. Failure times of an item are assumed to be exponentially distributed. It is also assumed that the uncertainty about the acceleration factor, the failure time contraction ratio between accelerated condition and use condition, can be modeled by the uniform or gamma prior distribution of appropriate parameters. We respectively use Bayes and maximum likelihood approaches to estimate acceleration factor and failure rate in the use condition. An example is given to show how the method can be applied.

• 한국농공학회지
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• 제37권3_4호
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• pp.82-89
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• 1995

The efforts of formulation have been reviewed and the results of existing laboratory experiments are investigated in order to describe the contracted flow which occurs at the final closure of sea dike construction. The regional characteristics of contracted flow is analyzed by checking the drawdown curve, and Chezy's mean velocity equation is employed to estimate the discharge rate at the closure. Weir-type discharge equations are reviewed, which are derived from Bernoulli equation, and the problems of the equations are discussed. Chezy's mean velocity equation is considered to be widely and generally applicable, and the empirical factor introduced in Chezy's equation is named 'form drag factor' since it is primarily dependent on the form drag caused by the contraction of discharge area. Laboratory experiments were conducted mainly in order to investigate the variation of form drag factor against various parameters, and an empirical equation is developed for the estimation of form drag factor.

• 한국수자원학회논문집
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• 제48권8호
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• pp.625-634
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• 2015

합류부에서의 지류의 합류각, 지류와 본류의 유량비에 추가하여, 본류 준설에 의한 하상고 불일치에 따른 다양한 양상의 분리구역의 특성을 CCHE2D 모형을 사용하여 분석하였다. 분리구역은 지류가 합류되어진 직후 단면에서의 유속이 0(영)인 경계로 정의하였다. 합류각 $30^{\circ}$ 이하에서는 분리구역이 형성되지 않았다. 유량비와 합류각 증가에 따른 분리구역의 크기는 일반적으로 증가하는 양상으로 나타났다. 준설 깊이비 증가에 따른 분리구역의 크기는 합류부 수용체의 증가에 기인한 지류에서의 상대적인 운동량의 감소로 인하여 감소되었다. 유량비와 합류각의 변화에 따른 분리구역의 수축지수를 규명하였고, 통수기능의 저하에 따른 배수영향을 확인하였다. 합류각, 유량비, 준설 깊이비에 따른 분리구역의 형상지수의 관계식을 제안하였다.

• Restorative Dentistry and Endodontics
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• 제28권6호
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• pp.457-466
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• 2003

The aim of study was to investigate the effect of flow, specimen geometry and adhesion on the measurement of linear polymerization shrinkage of light cured composite resins using linear shrinkage measuring device. Four commercially available composites - an anterior posterior hybrid composite Z100, a posterior packable composite P60 and two flowable composites, Filtek flow and Tetric flow-were studied. The linear polymerization shrinkage of composites was determined using 'bonded disc method' and 'non-bond-ed' free shrinkage method at varying C-factor in the range of 1∼8 by changing specimen geometry. These measured linear shrinkage values were compared with free volumetric shrinkage values. The viscosity and flow of composites were determined and compared by measuring the dropping speed of metal rod under constant load. In non-bonded method, the linear shrinkage approximated one third of true volumetric shrink-age by isotropic contraction. However, in bonded disc method, as the bonded surface increased the linear shrinkage increased up to volumetric shrinkage value by anisotropic contraction. The linear shrinkage value increased with increasing C-factor and approximated true volumetric shrinkage and reached plateau at about C-factor 5∼6. The more flow the composite was, reduced linear shrinkage was measured by compensation radial flow.

• 한국추진공학회지
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• 제1권1호
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• pp.55-63
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• 1997

본 연구에서는 기본적인 배관요소 중의 하나인 급축소/확대관을 지나는 압축성 유동을 해석하기 위하여 압축성 유체에 대한 이론계산을 수행하였다. 관 입구에서 유동의 마하수, 단면적 축소 및 확대비 등을 변화시켜, 압축성 효과 및 유동의 초우킹 조건 등을 구하였다. 본 연구의 결과들은 배관계를 설계하는데 기초자료가 될 뿐만 아니라 배관계를 지나는 압축성 유동에 대한 실용적인 계산법으로 활용될 수 있다.

• The Korean Journal of Physiology and Pharmacology
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• 제16권1호
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• pp.59-64
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• 2012

Hypoxic pulmonary vasoconstriction (HPV) is physiologically important response for preventing mismatching between ventilation and perfusion in lungs. The HPV of isolated pulmonary arteries (HPV-PA) usually require a partial pretone by thromboxane agonist (U46619). Because the HPV of ventilated/perfused lungs (HPV-lung) can be triggered without pretone conditioning, we suspected that a putative tissue factor might be responsible for the pretone of HPV. Here we investigated whether HPV can be also observed in precision-cut lung slices (PCLS) from rats. The HPV in PCLS also required partial contraction by U46619. In addition, $K^+$ channel blockers (4AP and TEA) required U46619-pretone to induce significant contraction of PA in PCLS. In contrast, the airways in PCLS showed reversible contraction in response to the $K^+$ channel blockers without pretone conditioning. Also, the airways showed no hypoxic constriction but a relaxation under the partial pretone by U46619. The airways in PCLS showed reliable, concentration-dependent contraction by metacholine ($EC_{50}$, ~210 nM). In summary, the HPV in PCLS is more similar to isolated PA than V/P lungs. The metacholineinduced constriction of bronchioles suggested that the PLCS might be also useful for studying airway physiology in situ.

• 한국전문물리치료학회지
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• 제9권2호
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• pp.115-131
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• 2002

Functional electrical stimulation (FES) training of the knee extensors is a useful way to rehabilitate the ability to stand and walk. However, training using FES has not been able to solve the problem of fatigue; clinical application of FES quickly produces muscle fatigue, due to the continuous activation of the muscles of the lower extremity. Therefore, reduction of muscle fatigue is an important factor in increasing the effectiveness of FES training in paraplegia. Intermittent high frequency alternating stimulation is a method that combines the advantages of high frequency (leading to strong muscle contractions) and alternating stimulation (reducing muscle fatigue), thereby continuously strengthening muscles. It is not known whether low frequency simultaneous stimulation results in stronger muscle contraction than high frequency alternating stimulation. This study compared the effectiveness of high frequency alternating stimulation with low frequency synchronized stimulation. Muscle power using FES on the quadriceps of 20 normal subjects were compared. Intermittent high frequency alternating stimulation did not produce more powerful muscle contraction than intermittent low frequency synchronized stimulation, because the muscle characteristics differed individually. Significant individual variation according to muscle characteristics was founded when applying FES. Accordingly, when physical therapists use FES to treat patients, they must be aware of individual variation in muscle characteristics.