• 약학회지
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• 제45권3호
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• pp.287-292
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• 2001

To investigate whether phospholipase $A_2$pathway is involved in histamine release of rat peritoneal mast cells, we measured histamine release in the presence of various enzyme inhibitors involved in eicosanoid pathway, such as phospholipase $A_2$, cyclooxygenase and lipoxygenase. Phospholipase $A_2$inhibitors, manoalide and OPC, significantly inhibited histamine release induced by 100 $\mu$M ATP and 1$\mu$g/ml compound 48/80. Cyclooxygenase inhibitors, ibuprofen and indomethacin, significantly inhibited ATP-induced histamine release and lipoxygenase inhibitors, baicalein and caffeic acid, also significantly inhibited. To investigate the involvement of protein kinase in ATP- and compound 48/80-induced histamine release, we observed effects of protein kinase inhibitors on histamine release. Bisindolmaleimide (protein kinase C antagonist) dose-dependently inhibited both ATP and compound 48/80-induced histamine release. Tyrosine kinase inhibitors (methyl 2,5-dihydroxy cinnamate and genistein) dose-dependently inhibited ATP and compound 48/80-induced histamine release. Protein kinase C and tyrosine kinase seem to be involved in histamine release induced by ATP and compound 48/80. These results suggest that phospholipase $A_2$pathway as well as protein kinase C and tyrosine kinase are involved in histamine release of rat peritoneal mast cells by ATP and compound 48/80.

• 대한화학회지
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• 제7권2호
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• pp.170-173
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• 1963

A tri-thiocyanate molybdenum (Ⅴ) complex containing pyridine has been prepared by one step process; namely, the solvent extraction of molybdenum (Ⅴ)-thiocyanate complex into organic solvents followed by precipitation of the compound by addition of pyridine to the extract. It is concluded that the compound has a definite composition regardless of the various mole ratios of molybdenum to thiocyanate ion employed in the preparation. The use of hydrazine as the reducing agent eliminates the necessity of working under inert atmosphere and of further purification of the product. Molybdenum (Ⅴ)-thiocyanate (1:3) complex can be quantitatively and selectively extracted with slightly polar organic solvents such as ethyl acetate, and the pyridine complex is quantitatively obtained due to the insolubility of the compound in them. The oxidation state of molybdenum in the compound is + 5 and the formula appears to be $MoH_2O_2(NCS)_3Py_2$ from the contents of Mo and NCS in the compound. The solubility of the compound in various has been studied at $25^{\circ}C$.

• 한국연초학회지
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• 제19권1호
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• pp.33-39
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• 1997

Recently the method of basal compound fertilizer (N : P : K = 18.2 : 9.8 : 35.0) Placement has been changed from banding to broadcasting in tobacco cultivation. The effects of the compound fertilizer placement, level of fertilizer and additional urea application on the agronomic characteristics, two chemical compositions and physical Properties of burley tobacco(Nicotiana tabacum L. cv. KB 108) were investigated at Chonju Experiment Station, Korea Ginseng and Tobacco Research Institute in 1995-1996. Six treatments consisted of (1) band (method of fertilizer Placement) + In kg/10a(compound fertilizer) + 0(additional urea applied), (2) broadcast+140+0, (3) broadcast+140+25, (4) band+180+0, (5) broadcast+180+0, and (6) broadcast +180+25. The additional urea was applied at hilling. No significant differences were detected between banding and broadcasting method of compound fertilizer Placement in field 9rowth, wield, organoleptic qualify(price Per kilogram), chemical composition and Physical properties of cured leaf, The increased compound fertilizer by 30%(40k/10a) or the additional urea application by 25kg per 10a produced slightly higher yield than the recommended amount of basal compound fertilizer without additional urea application did. It also increased the total alkaloid content of cured leaf. It is recommended that no more basal fertilizer above the recommended amount and no additional urea application are needed in burley tobacco fertilization, even though the method of basal fertilizer placement being chanced from banding to broadcasting. Key words : Nicotiana tabacum, fertilizer placement, additional urea.

• 한국의류산업학회지
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• 제11권1호
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• pp.6-13
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• 2009

The purpose of this study is to analyze the sensibility of the compound fashion image of contemporary fashion. The specific objectives were to analyze 1)the structure of meaning about fashion sensibility on 2)the difference of fashion sensibility by categories on 3)the difference of fashion sensibility by demographical aspects on 4)the consumer sensibility on the compound fashion image. For collecting data 55 stimulus and questionnaire which consisted of bi-polar 21 pairs adjective scale were contributed 675. The results were summarized as following : 1. Factors of fashion sensibility consist of estheticism, activeness, personality and feminity. And the meaning of fashion sensibility is young and personalty. 2. The man/woman and the past/present are highly estimated personality, the main/subcultural is activeness and the local/global is feminity of fashion sensibilities. 3. gender and age have high difference of the compound fashion image so they are important variance for fashion sensibilities. 4. Preference, purchase and quality are highly influenced by estheticism, pleasure is influenced by personality. The results of this study will be utilized in the clothing design for accepting customers' specific fashion sensibility about compound fashion image.

• 대한기계학회논문집A
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• 제28권11호
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• pp.1768-1775
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• 2004

The compressive axial collapse tests were performed to investigate collapse modes and energy absorption characteristics of Al/CFRP compound tubes which are aluminum tubes wrapped with CFRP(Carbon Fiber Reinforced Plastics) outside the aluminum circular and square tubes. Based on collapse characteristics of aluminum tubes and CFRP tubes respectively, the axial collapse tests were performed for Al/CFRP compound tubes which have different CFRP orientation angles. Test results showed that Al/CFRP compound tubes supplemented the unstable brittle failure of CFRP tubes due to ductile nature of inner aluminum tubes. In the light-weight aspect, specific energy absorption were the highest for Al/CFRP, CFRP in the middle, and aluminum the lowest. Also, specific energy absorption of circular tubes was higher than square tubes'. It turned out that CFRP orientation angle of Al/CFRP compound tubes influence specific energy absorption together with the collapse modes of the tubes.

• 설비공학논문집
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• 제23권2호
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• pp.132-138
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• 2011

In the present article, we investigate numerically turbulent flow of air through compound rectangular channels. Large eddy simulation(LES) is employed for unsteady turbulence modeling. LES gives better predictions for the axial mean velocity distribution than those of other turbulent models. Strong large-scale quasi-periodic flow oscillations are observed in most of the geometries investigated. Such large-scale flow oscillations in compound rectangular channels are similar to the quasi-periodic flow pulsation through the gaps between fuel rod bundle in nuclear reactor. It exists in any longitudinal connecting gap between two flow channels. The frequency of this flow oscillation is determined by the geometry of the gap. The large scale cross motions through the rectangular compound channels induce significant heat transfer enhancement of the compound channel flow.

• 대한약침학회지
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• 제15권1호
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• pp.12-17
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• 2012

Objectives: This study was designed to investigate the protective effects of Atractylodis Rhizoma pharmacopuncture (ARP) against acute gastric mucosal lesions induced by compound 48/80 in rats. Methods: The ARP was injected in Joksamni (ST36) and Jungwan (CV12) 1 hr before treatment with compound 48/80. The animals were sacrificed under anesthesia 3 hrs after treatment with compound 48/80. The stomachs were removed, and the amounts of gastric adherent mucus, gastric mucosal hexosamine, thiobarbituric acid reactive substances (TBARS), xanthine oxidase (XO), and superoxide dismutase (SOD) were measured. Also, histological examination were performed. Results: Gastric adherent mucus, gastric mucosal hexosamine and histological defects of gastric mucosa declined significantly after ARP treatment. Changes in gastric mucosal TBARS were also reduced by ARP treatment, but this result was not statistically significant. ARP treatment did not change the XO and the SOD activities. Conclusions: ARP showed protective effects for acute gastric mucosal lesions induced by compound 48/80 in rats. These results suggest that ARP may have protective effects for gastritis.

• 조명전기설비학회논문지
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• 제25권5호
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• pp.54-60
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• 2011

This paper presents characteristics of frequency-dependent grounding impedance and transient grounding impedance for the carbon compound grounding electrode used in the installation of computerized electronic equipment and lightning protection system. The frequency-dependent grounding impedances were measured by applying sinusoidal currents in the frequency range from 100 [Hz] to 10[MHz], and the transient grounding impedances were examined by subjecting the impulse current with the front-time between 1~80[${\mu}s$]. As a result, the ground resistance of the carbon compound grounding electrode is less than that of another type grounding electrodes. The transient grounding impedance is relatively low and the conventional grounding impedance is rather lower than the ground resistance. The frequency-dependent grounding impedance of the carbon compound grounding electrode is capacitive and the grounding impedance is decreased with increasing the frequency of injected currents. Therefore in the case that the carbon compound grounding electrode is jointly used with large-scaled grounding electrodes, it is possible to reduce the high frequency grounding impedance of the integrated grounding electrode system.

• 생약학회지
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• 제31권4호
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• pp.449-454
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• 2000

In search for plant-derived cytotoxic compounds, it was found that the $CHCl_3$ and EtOAC extracts obtained from the flowers of Paulownia coreana Uyeki (Scrophulariaceae) exhibited significant cytotoxic activity against human tumor cell lines, A549, SK-OV-3, SK-MEL-2, XF498, and HCT15. Activity-guided fractionation on the basis of the inhibitory activity against the growth of human tumor cell lines, in vitro, and repeated column chromatography afforded several cytotoxic compounds from P. coreana. The structures and stereochemistry of these compounds were established, on the basis of analysis of spectra including IR, UV, EI-MS, $^{1}H-NMR,\;^{13}C-NMR$ and some chemical transformations, as Compound PCCl $(2-hydroxy-4(15),11(13)-eudesmadien-8{\beta},12-olide)$, Compound $PCC2(2,3-dihydro-4-hydroxy-1(15),11(13)-xanthadien-8{\beta},12-olide)$, Compound PCE1 (chrysophanol), Compound PCE2 (emodin), Compound PCE3 (physcion). Cytotoxic activity of compounds obtained from P. coreana. on five tumor cells lines was evaluated by procedure of SRB methods.

• 한국표면공학회지
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• 제20권4호
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• pp.144-153
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• 1987

In the case of dipping the Ni-Resist cast iron into molten aluminum with iron content, the thickness of intermetallic compound was remarkably increased with increasing iron content. The thickness was shown by following equation in the range of 1-3% iron content; $x=22.5t^{1/2}+4.47{\cdot}t{\cdot}(Fe%)$. where, x is thickness(${\mu}m$), t the time (minute), Fe% the iron w/o. When the Ni-Resist cast iron was dipped into the molten aluminum containing zinc content, the intermetallic compound thickness was also increased with increasing zinc contents. And thickness was represented by the following equation in the range of 2-10% zinc content; $x=3.46t^{1/2}+0.27{\cdot}t{\cdot}(Zn%)$. However, in the case of dipping the Ni-resist cast iron into molten aluminum with silicon content, the thickness of intermetallic compound was decreased with increasing silicon content, as shown in the following equation; $x=7.17t^{1/2}-0.15{\cdot}t{\cdot}(Si%)$. The intermetallic compound formed onto Ni-Resist cast iron was identified to be $FeAl_3\;and\;Fe_3Al$. As the result of hardness measurement, the peak hardness appeared in the intermetallic compound at near interface of the cast iron and the compound.