• 한국군사과학기술학회지
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• 제24권1호
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• pp.144-150
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• 2021

This study was designed to evaluate the prophylactic efficacy of a combinational patch system containing physostigmine and procyclidine against sarin and soman using guinea pig. The median lethal dose values of two nerve agents were calculated by a probit analysis of deaths occurring within 24 h. In this study, the values of median lethal dose of sarin and soman were determined to be 33.0 and 26.7 ㎍/kg in guinea-pigs, respectively. The guinea pigs treated with a prophylactic patch(4×5 ㎠) for 24 h were 100 % protected against a challenge of 1.5 LD50. The combinational KMARK-1(atropine and 2-PAM) and prophylactic patch were more effective than a single KMARK-1, a combination of pyridostigmine and KMARK-1 significantly. Epileptiform seizures in the guinea pigs treated with the combinational antidotes led to neuropathological changes, in comparison with intact feature of brain of the animal treated with the patch.

• International Journal of Naval Architecture and Ocean Engineering
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• 제12권1호
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• pp.314-324
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• 2020

Due to the nonlinearity and environmental uncertainties, the design of the ship's steering controller is a long-term challenge. The purpose of this study is to design an intelligent autopilot based on Extended Kalman Filter (EKF) trained Radial Basis Function Neural Network (RBFNN) control algorithm. The newly developed free running model scaled surface vessel was employed to execute the motion control experiments. After describing the design of the EKF trained RBFNN autopilot, the performances of the proposed control system were investigated by conducting experiments using the physical model on lake and simulations using the corresponding mathematical model. The results demonstrate that the developed control system is feasible to be used for the ship's motion control in the presences of environmental disturbances. Moreover, in comparison with the Back-Propagation (BP) neural networks and Proportional-Derivative (PD) based control methods, the EKF RBFNN based control method shows better performance regarding course keeping and trajectory tracking.

• Current Photovoltaic Research
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• 제11권1호
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• pp.18-26
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• 2023

Tin perovskite solar cells have attracted a lot of attention due to their potential to address the toxicity of lead, which is the biggest barrier to commercialization of perovskite solar cells. Unlike other lead-free perovskite, tin perovskite have a direct bandgap, which is suitable for use as light harvesting, and relatively good stability, which has led to a lot of attention. Since the first tin perovskite solar cell was reported in 2014, it has achieved an impressive power conversion efficiency of 14.81%. However, this efficiency is still low compared to that of lead perovskite solar cells, and the stability of tin perovskite solar cells is also an issue that needs to be addressed. In this review, we will discuss the basic properties of the tin atom in comparison to the lead atom, and then discuss the crystal structure, phase transition, and basic properties of tin perovskite. We will then discuss the advantages, applications, challenges, and strategies of tin perovskite, In particular, we will focus on how to prevent the oxidation of tin, which is arguably the biggest challenge for using tin perovskite solar cells. At the end, we summarize the key factors that need to be addressed for higher efficiency and stability, emphasizing what is needed to commercialize tin perovskite solar cells.

• Structural Engineering and Mechanics
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• 제87권3호
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• pp.273-282
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• 2023

Concrete construction, one of the oldest building practices, is commonly used in all parts of the world. Concrete is the primary building material for both residential and commercial constructions. The challenge of protecting the buildings, hence nation, against the attack of terrorism has raised the importance to explore the understanding of building materials against the explosion. In this research, a security check-post (reinforced concrete frame filled with plain cement concrete) has been chosen to study the behavior of structural elements under blast loading. Eight nitroglycerines-based dynamite blasts with varying amounts of explosive charge, up to 17 kg weight has been carried out at various scale distances. Pressure and acceleration time history records are measured using blast measuring instruments. Security check post after being exposed by explosive loading are photographed to view cracking/failure patterns on the structural elements. It is noted that with the increase of quantity of explosive, the dimensions of spalling and crack patterns increase on the front panels. Simple empirical analyses are conducted using ConWep and other design manuals such as UFC 3-340-02 (2008) and AASTP-1 (2010) for the purpose of comparison of blast parameters with the experimental records. The results of experimental workings are also compared with earlier researchers to check the compatibility of developed equations. It is believed that the current study presents the simple and preliminary procedure for calculating the air blast and ground shock parameters on the structures exposed to blast explosion.

• 산업경영시스템학회지
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• 제47권1호
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• pp.9-19
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• 2024

Deep learning-based computer vision anomaly detection algorithms are widely utilized in various fields. Especially in the manufacturing industry, the difficulty in collecting abnormal data compared to normal data, and the challenge of defining all potential abnormalities in advance, have led to an increasing demand for unsupervised learning methods that rely on normal data. In this study, we conducted a comparative analysis of deep learning-based unsupervised learning algorithms that define and detect abnormalities that can occur when transparent contact lenses are immersed in liquid solution. We validated and applied the unsupervised learning algorithms used in this study to the existing anomaly detection benchmark dataset, MvTecAD. The existing anomaly detection benchmark dataset primarily consists of solid objects, whereas in our study, we compared unsupervised learning-based algorithms in experiments judging the shape and presence of lenses submerged in liquid. Among the algorithms analyzed, EfficientAD showed an AUROC and F1-score of 0.97 in image-level tests. However, the F1-score decreased to 0.18 in pixel-level tests, making it challenging to determine the locations where abnormalities occurred. Despite this, EfficientAD demonstrated excellent performance in image-level tests classifying normal and abnormal instances, suggesting that with the collection and training of large-scale data in real industrial settings, it is expected to exhibit even better performance.

• International Journal of Computer Science & Network Security
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• 제24권6호
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• pp.23-32
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• 2024

Mobile Ad hoc Network is a network of multiple wireless nodes which communicate and exchange information together without any fixed and centralized infrastructure. The core objective for the development of MANET is to provide movability, portability and extensibility. Due to infrastructure less network topology of the network changes frequently this causes many challenges for designing routing algorithms. Many routing protocols for MANET have been suggested for last few years and research is still going on. In this paper we review three main routing protocols namely Proactive, Reactive and Hybrid, performance comparison of Proactive such as DSDV, Reactive as AODV, DSR, TORA and Hybrid as ZRP in different network scenarios including dynamic network size, changing number of nodes, changing movability of nodes, in high movability and denser network and low movability and low traffic. This paper analyzes these scenarios on the performance evaluation metrics e.g. Throughput, Packet Delivery Ratio (PDR), Normalized Routing Load(NRL) and End To-End delay(ETE).This paper also reviews various network layer security attacks challenge by routing protocols, detection mechanism proposes to detect these attacks and compare performance of these attacks on evaluation metrics such as Routing Overhead, Transmission Delay and packet drop rates.

• Hip & pelvis
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• 제36권2호
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• pp.101-107
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• 2024

Treatment of femoral bone defects continues to be a challenge in revision total hip arthroplasty (THA); therefore, meticulous preoperative evaluation of patients and surgical planning are required. This review provides a concise synopsis of the etiology, classification, treatment strategy, and prosthesis selection in relation to femoral bone loss in revision THA. A search of literature was conducted for identification of research articles related to classification of bone loss, management of femoral revision, and comparison of different types of stems. Findings of a thorough review of the included articles were as follows: (1) the Paprosky classification system is used most often when defining femoral bone loss, (2) a primary-length fully coated monoblock femoral component is recommended for treatment of types I or II bone defects, (3) use of an extensively porous-coated stem and a modular fluted tapered stem is recommended for management of types III or IV bone defects, and (4) use of an impaction grafting technique is another option for improvement of bone stock, and allograft prosthesis composite and proximal femoral replacement can be applied by experienced surgeons, in selected cases, as a final salvage solution. Stems with a tapered design are gradually replacing components with a cylindrical design as the first choice for femoral revision; however, further confirmation regarding the advantages and disadvantages of modular and nonmodular stems will be required through conduct of higher-level comparative studies.

• Clinical and Experimental Pediatrics
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• 제51권8호
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• pp.842-847
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• 2008

목 적 : 기도 폐쇄의 평가를 위해 측정하는 $FEV_1$은 대상 환자의 협조를 필요로 하기 때문에 6세 이전의 소아에서는 검사하기 어렵다. 이에 본 연구에서는 소아에서 IOS의 유용성을 검정하기 위해 IOS와 폐활량 측정법의 $FEV_1$을 비교하였다. 방 법 : 병력상 천식이 의심되어 폐활량 측정법과 IOS를 이용해서 폐기능 검사 및 메타콜린 기관지 유발 검사를 실시한 환자 174명을 대상으로 하였다. 대상군은 기관지 과민성 지표인 $PC_{20}$ 농도에 따라 두 군으로 나누었고, 이들의 기저 폐 기능, 기관지 유발검사 후의 변화율, $FEV_1$과 IOS 지표의 상관관계를 알아보았다. 결 과 : 기저 폐기능 지표 중 X5, R5는 $PC_{20}$ 양성군과 음성군간에 유의한 차이를 보였지만, $FEV_1$, $FEV_1$ % 예측치, $FEV_1_-Zs$은 유의한 차이가 없었다. $FEV_1$은 X5 (r=0.45, P<0.01), R5 (r=-0.69, P<0.01)와 상관관계를 보였고, $FEV_1_-Zs$ 역시 X5_Zs (r=-0.26, P<0.01), R5_Zs (r=-0.31, P<0.01)와 상관관계를 보였다. 메타콜린 유발검사 후 $FEV_1$과 X5의 변화율은 두 군간에 유의한 차이를 보였다(P<0.05). 결 론 : IOS 지표는 기저 폐 기능 검사에서 기관지 과민성으로 분류한 환자를 $FEV_1$보다 민감하게 구분 지을 수 있었고, IOS 지표와 $FEV_1$의 상관관계가 높았다.

• 대한핵의학회지
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• 제37권2호
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• pp.94-102
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• 2003

목적: 아세타졸아마이드를 이용한 뇌혈류 SPECT는 폐쇄성 뇌혈관질환이 있는 환자에서 혈역학적 부전을 평가 하는데 유용하다. 본 연구는 아세타졸아마이드 부하 $^{123}I-IMP$ SPECT를 실시하여 뇌국소부위의 혈역학적 부전의 정도를 정확히 평가할 수 있는지를 살펴보았다. 대상 및 방법: 뇌혈관 질환이 의심되는 18명의 (남: 16, 여: 2, 평균연령 61세) 환자를 대상으로 하였다. 뇌국소부위의 혈관확장 예비능을평가하기 위하여 아세타졸아마이드 투여후 $^{123}I-IMP$ SPECT를 실시하였다. PET은 SPECT 검사 전후로 2주 이내의 간격을 두고 실시하였으며, 뇌혈류, 산소추출분획, 뇌산소대사율 및 뇌혈액량을 구하였다. 모두 46개의 직사각형의 관심영역 (ROIs)을 4개의 다른 뇌단층면에서 직접그리고 병변 부위의 관심영역내에서의 $^{123}I-IMP$ 섭취와 반대측의 동일영역의 관심영역에서 $^{123}I-IMP$ 섭취비율인 AI 를 구하여 PET 에서 얻어진 자료들과 비교하였다. 결과: 18명의 환자의 414 개의 해부학적 영역에서의 뇌의 혈역학적인 평가는 각 환자의 산소수출분획과 뇌혈류/뇌혈액량에 따라 정상 (n=107), stage I (n=117) 또는 stage II (n=140) 로 나누었다. 혈관 확장 예비능을 나타내는 ${\triangle}AI$ (아세타졸아마이드투여시 AI 값-기저상태의 AI 값) 의 값은 정상, stage I 및 stage II 에서 각각 $-6.25{\pm}7.77%,\;-10.38{\pm}10.41%$ 및 $-13.30{\pm}10.51%$으로 세군간에 유의한 차이가 있었다 (p<0.05). 뇌혈관 협착이 있는 대뇌반구에서 ${\triangle}AI$와 뇌혈류량, 산소추출분획 및 뇌혈액량/뇌혈류량의 상관계수는 각각 0.20, -0.28 및 -0.28로 통계적으로 유의한 상관관계를 보였다(p<0.01). 결론: 정상인과 stage I 그리고 stage II 의 혈역학적부전 환자들간의 뇌혈관확장 예비능에 유의한 차이가 있었으며, 이러한 결과로 볼 때 아세타졸아마이드 부하에 대한 국소뇌혈류의 변화는 뇌관류압에 대한 보상적 혈관확장의 정도를 비교적 정확히 반영할 수 있다고 볼 수 있다.

• 벤처혁신연구
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• 제3권1호
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• pp.143-163
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• 2020

본 연구는 성공적인 경영성과를 창출할 수 있는 소공인 CEO의 특성을 파악하여 실증적으로 분석하고, 이를 분석하는 과정에서 지식경영의 매개적 역할에 주목하여 지식경영이 어떤 역할을 하는지 파악하기 위한 목적으로 수행되었다. 소공인이 성공적인 경영성과를 창출하기 위해 소공인CEO의 대인유연성과 스트레스 내성이 직접적으로 경영성과에 미치는 영향을 규명하고, 이에 더 나아가 도전정신과 글로벌 역량이 지식경영을 매개로 경영성과에 미치는 영향을 검정하고자 하였으며, 선행연구를 통해 연구모형을 도출하고, 소공인 CEO를 대상으로 실증조사를 통해서 다음과 같은 결과를 도출하였다. 첫째, 소공인의 글로벌 역량이 경영성과에 직접적인 영향을 미치는 것으로 분석되었다. 둘째, 소공인의 스트레스 내성이 경영성과에 직접적인 영향을 미치는 것으로 분석되었다. 셋째, 소공인의 도전정신이 경영성과에 미치는 정(+)의 영향은 지식경영에 의해 완전 매개되는 것으로 나타났으며, 넷째, 소공인의 대인 유연성이 경영성과에 미치는 정(+)의 영향은 지식경영에 의해 부분 매개되었다. 이러한 연구결과는 기술 집약형의 소공인 업체가 적은자원을 투입하고도 스스로 활성화가 가능한 지식생태계를 구축하여 경영의 성공확률을 높일 수 있음을 시사하고 있다. 풍부한 지식경영의 노하우를 보유한 소공인이 지적자산의 가치를 이해하고, 이렇게 얻어진 지식을 어떻게 보다 효과적으로 시장가치로 전환 할 수 있을지 고민하며, 그 것이 성공적인 기업성과를 창출하는데 얼마나 중요한지를 보여주고 있다. 지식을 효과적으로 사용하기 위해 지식경영에 기술을 통합하는 최선의 방법과 소공인 CEO가 지식경영에서 얻어진 경험, 직감, 신념 등의 가치가 성공적으로 경쟁 우위를 확보하거나 유지할 수 있는 조건으로 어떻게 탄생할 것인가를 주목하고 인식하여 의지를 다져야 함을 시사하고 있다.