• 동의생리병리학회지
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• 제22권6호
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• pp.1410-1415
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• 2008

Acupuncture and herbal treatment are based on diagnosis of cold and heat pattern in Traditional Korean Medicine. This diagnosis is accomplished through pulse, tongue and question examination, which are not objective. Quantification and objectification of this diagnosis process are required for efficacious treatment and traditional medicine development. In this study, we developed the cold-heat pattern questionnaire for this purpose. Seventy nine patients who visited oriental medical hospital were included in this study. The cold-heat pattern questionnaire was composed of many questions about patient's physical condition, which were derived from The Traditional Oriental Medical Literature with Delphi Technique. Patients filled out the cold-heat pattern questionnaire by themselves. Diagnosis of cold and heat pattern are conducted separately by oriental medical doctors with more than 5 years' clinical experience. Various physical condition factors were derived for the cold-heat pattern questionnaire. (Preference temperature, Body temperature, Pain type, Face color, Urine, Stool and secretion features) Each cold and heat symptoms group acquired internal consistency. (Cronbach's ${\alpha}$ : Cold - 0.605, Heat - 0.722) There were significant associations between doctor's diagnosis and cold symptoms in 'Aversion to cold', 'Desire for heat', 'Pale face', 'Loose stools'. (p-value < 0.05) There were significant associations between doctor's diagnosis and heat symptoms in 'Desire for cold', 'Body feverishness', 'Thirst'. (p-value < 0.05) The internal consistency results suggest that the cold-heat pattern questionnaire assured reliability. Besides, these results showed that cold-heat symptoms are apt to appear together with, and this can be indirect evidence that diagnosis of cold-heat pattern is valuable for comprehension about disease pattern. Moreover, respective symptoms of cold-heat pattern showed different significance with doctor's diagnosis. Consequently these significant symptoms can be more considered for comprehension of cold-heat pattern.

• 대한한의학회지
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• 제42권4호
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• pp.185-196
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• 2021

Objectives: Many symptoms of cold and heat patterns are related to the thermoregulation of the body. Thus, we aimed to study the association of cold and heat patterns with anthropometry/body composition. Methods: The cold and heat patterns of 2000 individuals aged 30-55 years were evaluated using a self-administered questionnaire. Results: Among the anthropometric and body composition variables, body mass index (-0.37, 0.39) and fat mass index (-0.35, 0.38) had the highest correlation coefficients with the cold and heat pattern scores after adjustment for age and sex in the cold-heat group, while the correlation coefficients were relatively lower in the non-cold-heat group. In the cold-heat group, the most parsimonious model for the cold pattern with the variables selected by the best subset method and Lasso included sex, body mass index, waist-hip ratio, and extracellular water/total body water (adjusted R² = 0.324), and the model for heat pattern additionally included age (adjusted R² = 0.292). Conclusions: The variables related to obesity and water balance were the most useful for predicting cold and heat patterns. Further studies are required to improve the performance of prediction models.

• 사상체질의학회지
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• 제29권4호
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• pp.326-335
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• 2017

Objectives The purpose of this study was to analyze the difference of cold-heat pattern according to sasang constitution. Methods 3891 subjects were joined in this study. The sasang cinstitution diagnosis were proceeded by sasang constitution experts. The questionnaires and anthropometric measurements of the subjects were collected. Results The effect of gender and body mass index on the cold-heat pattern according to sasang constitution were significant. The effect of age on the cold-heat pattern according to sasang constitution were not significant. The distribution of short form-12 and blood test on the cold-heat pattern according to sasang constitution were significant. Conclusions There were significant different distribution of cold-heat pattern asscording to sasang constitution by gender, body mass index, short form-12, blood test.

• 대한한방부인과학회지
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• 제25권4호
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• pp.27-37
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• 2012

Purpose: Dysmenorrhea is mostly depending on the causative factor, which usually falls under the categories of Cold and Heat pattern in traditional Oriental medical theories and diagnosis. Thus, we investigated menstruation symptom and sign related to dysmenorrhea and verified the validity of Cold and Heat pattern identification. Methods: We investigated menstruation symptom and sign related to dysmenorrhea in total 14 gynecology-medical books including ${\ll}$Exemplar Of Korean Medicine (Dongui Bogam)${\gg}$ and whole body symptom and sign identifying Cold and Heat pattern at the same time. A survey based on this investigation was carried out targeting women of childbearing age. Results: According to 14 gynecology-medical books, polymenorrhea is relevant to Heat pattern, oligomenorrhea to Cold pattern and darkness of menstrual blood is relevant to Heat pattern. Among the total of 343 womens, 196 subjects suffered from dysmenorrhea. The number of dysmenorrhea with polymenorrhea(Heat pattern) was 6 person, with oligomenorrhea(Cold pattern) was 27 person. And the number of dysmenorrhea with darkness of menstrual blood(Heat pattern) was 39 person. As the result of checking correlations of menstrual symptom scores and whole body symptom scores, there was no significance of Cold and Heat pattern between menstrual symptoms and whole body symptoms. Conclusions: The results suggest that the period of menstrual cycle and the color of menstrual blood provides some informations of Cold and Heat pattern identification. But considering with other whole body symptom and sign is needed for more precise result.

• 대한한방내과학회지
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• 제34권3호
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• pp.267-277
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• 2013

Objectives : The aim of this study was to investigate the correlation between Cold-Heat pattern tendency and demographic traits, physical character, and vital signs in hypertensive patients taking anti-hypertensive agents. Methods : 28 hypertensive patients 30 to 69 years old were recruited. We assessed their general characteristics, physical characteristics (height, weight, waist circumference, etc.), vital signs without respiratory rate (blood pressure, pulse rate, temperature) and administered a Cold-Heat pattern questionnaire. After that, we analyzed statistical data on separate groups according to Cold-Heat characteristics or other criteria. Results : 1. Heat group patients had statistically higher scores in waist, body mass index (BMI), waist circumference and pulse rate. 2. Over weighted group patients had statistically lower scores in cold Pattern Identification. 3. Higher BMI group (above 23/25) patients had statistically significantly higher Heat scores and lower Cold scores, higher waist circumference group patients had lower Cold scores. Conclusions : From the above result in hypertensive patients taking hypertensive agents, Heat group had a obesity tendency and the inverse is also valid. Later, progressed study based on more samples and varied data will contribute to diagnosis the Cold-heat Pattern identification in hypertensive patients.

• 동의생리병리학회지
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• 제33권3호
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• pp.163-168
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• 2019

In order to enhance the 8 principle pattern diagnosis rate comparing with diagnostic method by self-report questionnaire on cold/heat pattern in the clinical practice, a new diagnostic method using form-color-pulse-symptom (FCPS) system is proposed. FCPS system is composed of outputs of cold/heat pattern through the calculation process of contribution degree to the cold, heat pattern and qi, blood, yin, yang deficiency patterns, based on analysis of 16 mechanisms of disease calculated by diagnostic system of oriental medicine (DSOM) first. And second component is an output of differentiated 8 principle patterns in detail through binding and calculating process with digital informations of pulse, color, form, constitution obtained by computerized measurement system. Putting together above two processes consecutively, cold-heat complex or true/false cold/heat patterns and personalized characters of cold/heat patterns of each patient can be subdivided through a computation method of determining each pattern. In conclusion, 8 principle pattern identification can be performed more accurately using FCPS system than existent self report questionnaire method. These hypothetic proposal is needed to be proven by clinical trial for the future and then the accurate numbers used in each calculational function should be revised properly.

• 한방안이비인후피부과학회지
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• 제32권4호
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• pp.29-40
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• 2019

Objectives : Hwanglyeonhaedok-tang(黃連解毒湯) is a representative herbal formula with "clear heat(淸熱)" effects. The aim of this study was to evaluate the effects of Hwanglyeonhaedok-tang-based intranasal herbal ointment Biyeom-go based on the cold and heat pattern identification questionnaire(CHPIQ). Methods : We performed a subgroup analysis of the previously published prospective observational study. A total of 58 patients with rhinitis were administered Biyeom-go for 4 weeks, and its effects on the Total Nasal Symptom Score(TNSS), Mini Rhinoconjunctivitis Quality of Life Questionnaire(Mini-RQLQ) score, and nasal endoscopy index score were analyzed based on CHPIQ. Results : Among the 58 patients, the heat and non-heat patterns were shown by 39 and 19 patients, respectively, while the cold and non-cold patterns were shown by 46 and 12 patients, respectively. The change in TNSS from baseline negatively correlated with the heat pattern score(p=0.011). Improvement in TNSS was greater in the heat pattern group than in the non-heat pattern group, with a borderline significant difference(p=0.07). Mini-RQLQ and nasal endoscopy index scores tended to be lower in the heat pattern group than in the non-heat pattern group, but without a statistically significant difference. Conclusion : The findings indicate that CHPIQ is a useful tool for the diagnostic and prognostic evaluation of patients with rhinitis. This study provides fundamental evidence of the close association between the cold-heat pattern in patients with rhinitis and the treatment effects of Biyeom-go.

• 사상체질의학회지
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• 제32권3호
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• pp.18-32
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• 2020

Objectives In order to find out the relationship between the Eight Principle Pattern Identification of Cold-Heat, Deficiency-Excess and the Sasang constitution, we analyzed the clinical data from 500 women with menstrual pain and women without menstrual pain. Methods In the previous study, the subject's information of Typology Complexion Pulse and Symptom was collected, and Eight Principle Pattern Identification was executed based on this. Later, the relationship between the Sasang constitution and the Eight Principle Pattern Identification was statistically analyzed. Results and Conclusion 1. The obvious difference between the experimental group and the control group in the patterns of Cold-Heat and Deficiency-Excess is that patients who complain of menstrual pain do not maintain harmony with the yin-yang ratio, it can be said that the patterns of Cold-Heat and Deficiency-Excess can be a Identification standard that significantly obscures the condition of the disease. 2. There was a significant difference between the Sasang constitution and the Eight Principle Pattern Identification of Cold-Heat. There was no significant difference between the Sasang constitution and the Eight Principle Pattern Identification of Deficiency-Excess.

• 동의생리병리학회지
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• 제30권6호
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• pp.466-473
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• 2016

This study intended to find out the most substantial items in cold and heat pattern identification(CHPI) questionnaire based on usual symptoms through CHPI diagnosis and evaluation by experts. 120 participants, faculties of OO university, filled out CHPI questionnaire based on usual symptoms by the way of self-reporting. Then 2 Korean Medicine doctors independently diagnosed them whether they belonged to cold pattern identification(PI) or heat PI, and scored the result of it. Pearson correlation of 2 experts was 0.649 in cold PI and 0.605 in heat PI. Agreement was 75.8%(Kappa value 0.516) in cold PI and 74.2%(Kappa value 0.465) in heat PI. Pearson correlation of 2 experts was 0.649 in cold PI and 0.605 in heat PI. Agreement between two experts was 75.8%(Kappa value 0.516) in cold PI and 74.2%(Kappa value 0.465) in heat PI. Items of high correlation with experts' evaluation followed next: "do not usually like the cold", "usually like the warm", "usually feel cold" in cold PI and "do not usually like the hot", "usually feel hot", "usually feel burning sensation in the body" in heat PI. We could infer from that facts that experts give weight on 'subjective feeling of cold or heat in participants body' and 'preference on sensation of cold and heat'. We also expect this study to be an epidemiological foundation to disclose correlation between usual CHPI and diseases.

• 대한예방한의학회지
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• 제20권2호
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• pp.17-26
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• 2016

Objectives : We presented the results of reliability study in advance, and analyzed agreement between Korean medicine doctors(KMDs)' diagnosis and cold-heat pattern identification questionnaire(CHPI)'s diagnosis. Methods : This survey was conducted from May 16 to 17, 2015. The subjects were 93 adults living in rural society. Diagnosis of CHPI was performed by 2 KMDs who have clinical experience more than 5 years. The KMDs' diagnosis was set as a reference index, and then we compare 23 items(cold pattern 11 items and heat pattern 12 items) of CHPI questionnaire and 15 items(cold pattern 8 items and heat pattern 7 items) that were brief form of it. We had cut-off value by standard of KMDs' diagnosis using receiver operating characteristic-curve(ROC-curve), with which we calculated agreement including kappa value. Correlation analysis between CHPI evaluation score by KMDs and by the questionnaire was fulfilled as well. Results : Agreement about 11 and 8 cold pattern items showed 87.1% together, and the value of kappa each recorded 0.742 and 0.741. Agreement about 12 and 7 heat pattern items suggested 81.7% and 78.5%, and the value of kappa showed 0.634 and 0.570. Correlation coefficients were 0.803 of 11 items and 0.761 of 8 items about cold pattern. In addition, correlation coefficients were 0.789 of 12 items and 0.767 of 7 items about heat pattern. The significant probability (p-value) was under 0.001. Conclusions : We have developed CHPI questionnaire involving reliability and agreement based on usual symptoms, and hope additional complements so that Korean medicine diagnostics and Korean preventive medicine would be improved.