• Title/Summary/Keyword: Clinical research trend

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Relationship between White Spot Symptom and Physiological Status of Two Penaeid Shrimps

  • Kim, Su Kyoung;Kim, Myung Seok;Park, Myoung Ae;Kim, Su mi;Jang, In Kwon;Kim, Seok Ryel;Cho, Miyoung
    • Korean Journal of Environmental Biology
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    • v.35 no.4
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    • pp.461-467
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    • 2017
  • Shrimps infected with WSSV(White Spot Syndrome Virus) generally exhibit white spots in their inner space of carapaces as an acute clinical sign. In an effort to identify the correlation between this acute clinical sign and the condition, the index factors (RNA/DNA concentration and ratio, trypsin activity) were analyzed. A total 580 farmed Fenneropenaeus chinensis and 130 Lithopenaeus vannamei were collected from western and southern fifteen outdoor ponds in Korea. The status of the white spot pathology was divided into four stages (stage 0, stage I, stage II, and stage III), in accordance with the clinical signs as to the size and area of white spots. A significant decrease in RNA concentration and RNA/DNA ratio for multi-infected fleshy prawn (WSSV and vibrio sp.) occurred during the stage III (the whole carapace is covered with a white spot). In particular, RNA/DNA ratio was significantly lower as $1.47{\pm}0.04$ than other groups. A similar trend was also found in the single infection (WSSV), but the decrease was less than the multi-infection. In the species comparison, both species were vulnerable to the multi-infection, but L. vannamei was more sensitive than F. chinensis(ANOVA, p<0.05): A significant decrease in RNA concentration and RNA/DNA ratio was first found in stage II for the former species, while it was found in stage III for the latter species. Trypsin activity was also showed a similar tendency with nucleic acid variation. Multi-infected shrimp showed drastically decrease of trypsin activity. According to the results, clinical signs of the white spot under carapace have an only physiological effect on shrimp if they covered entirely with white spots.

Review on Conservative Treatment of Spinal Scoliosis (척추측만증의 보존적 치료에 대한 문헌적 고찰 - 국내 발표 논문을 중심으로 -)

  • Lee, Moon-Kyu;Lee, Gil-Jae;Song, Yun-Kyung;Lim, Hyung-Ho
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.4 no.1
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    • pp.103-117
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    • 2009
  • Objective : The purpose of this study is to research the trend of the theses related to conservative treatment of spinal scoliosis and to establish the direction of futher studies into the spinal scoliosis Methods : We reviewed and analyzed all theses published by Korean research institution. And these theses were classified by field of study, theses type, symptoms and illnesses, evaluation methods, treatment type, clinical outcome. Result and conclusion : 1. Classified by the major field of study, oriental rehabilitation medicine and physical education accounted for 9 papers, followed by 6 in orthopedics medicine. 2. Upon classifying theses according to research method type, clinical trial theses were more than casuistic theses. 3. Upon classifying theses according to symptoms and illnesses in scoliosis, the most was idiopathic scoliosis. 4. Theses used mostly Cobb's angle for evaluating in scoliosis. 5. Some few of theses used chuna therapy for treating in scoliosis. 6. Chuna therapies side by side with correction exercises were the most efficient for treating in scoliosis.

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A Review of a Clinical Study on Pharmacopuncture for Insomnia in China (중국에서의 약침을 활용한 불면증 치료 임상논문 연구동향)

  • Song, Guneui;Lim, Gyomin;Lee, Yeogyeong;Song, Geumju;Park, Se-jin
    • Journal of Oriental Neuropsychiatry
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    • v.30 no.3
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    • pp.265-274
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    • 2019
  • Objectives: The purpose of this study was to research the trend related to pharmacopuncture for insomnia in China for further development of pharmacopuncture in Korea. Methods: This study reviewed and analyzed 21 Chinese journals related to pharmacopuncture 2013~2019 sourced with the following keywords in the China National Knowledge Infrastructure (CNKI). 'Shimian', 'Wuewei zhushe', 'Shuizhen', 'Xuewei yaowu zhushe', 'Yaowu xuewei zhushe', 'Xuewei zhuyao', 'Xuezhu', and 'Xueweiyaowu zhuru'. Results: The following results were obtained in this study. 1. A total of 21 papers were selected, comprised of clinical research and case reports. 2. Pharmacopuncture was often used for insomnia, and as the medicine of injection, Salvia, Gastrodin, Acanthopanax, Hominis Placenta, Qingkailing, Shenmai, Bozhi Glycopeptide, Fufang Danggui, Vitamin B12, and Chlorpromazine Hydrochloride were used. 3. In combined treatments, acupuncture, chiropractic, auricular sticking, and herbal medicine were used. 4. It was more effective compared to conservational acupuncture therapy. Conclusions: It was established that they have efficiency to treat insomnia with pharmacopuncture in China, but there were limitations in this study, so we need more research to identify new medicines for neuropsychiatric diseases.

A Systematic Review of Herbal Medicine in the Treatment of Cirrhotic Ascites

  • Kim, Seungmo;Lee, Yuri;Cho, Nakyung;Choi, Hongsik;Kim, Kyungsoon
    • The Journal of Korean Medicine
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    • v.42 no.4
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    • pp.222-237
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    • 2021
  • Objectives: The purpose of this study was to investigate the trend in the research on cirrhotic ascites using t herbal medicine. Methods: This review was conducted using six electronic databases(NDSL, KMBASE, Koreantk, KISS, KISTI, KoreaMed) with no restriction in year. The search term was 'liver cirrhosis', 'ascites', or 'cirrhotic ascites', 'herbal medicine', 'traditional Chinese medicine', and 'randomized clinical trial', and there was no restriction in year. The searched studies were analyzed according to the type of research. Results: After scanning the titles and abstracts, 13 articles were ultimately included. Of the outcome measures of 13 studies, effective rate, liver function test, and ascites regression time were included in the meta-analysis, which showed that the effective rate of herbal medicine-supportive treatment combination therapy was 1.27 times higher than that of supportive treatment alone, and the difference was statistically significant. Conclusions: We analyzed the trends of cirrhotic ascites treatment in herbal medicine through this review. It is necessary to conduct further studies, such as well-designed clinical trials based on the results from experimental research.

Research Trend in Korean Medicine Treatment for Hemifacial Spasm

  • Hyang Gi Lim;Eun Sil Heo;Sang Ha Woo;Jung Hee Lee;Jae Soo Kim;Seong Hun Choi;Hyun-Jong Lee
    • Journal of Acupuncture Research
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    • v.40 no.3
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    • pp.201-213
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    • 2023
  • This study reviewed clinical papers reported on hemifacial spasm (HFS). Six online databases were searched for clinical papers published between January 2000 and December 2022. This study reviewed 14 studies, including 13 case reports and 1 combination of case reports and randomized controlled trials (RCTs). The most frequently used acupoints were ST7 and TE17, and the stomach meridian was the most frequently selected. Herbal medicine, pharmacopuncture, thread embedding acupuncture, cupping, moxibustion, and physical therapy were combined with acupuncture. The most frequently used evaluation method is Scott's scale. Out of 95 cases, 82 reported improved HFS symptoms after treatment. Our findings indicated the effectiveness of Korean Medicine treatment in treating HFS. However, evidence of efficacy and safety remains insufficient. Large-scale and well-designed investigations will be required in the future to corroborate these results. We believe that this paper will serve as the foundation for future RCTs.

An Analysis of Nursing Research on the Family with chronfcally ill children in Borea (만성환아의 가족에 관한 국내 연구논문 분석)

  • Jung Yun;Lee Kun Ja;Paik Seung Nam;Cho Kyoul Ja
    • Child Health Nursing Research
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    • v.2 no.1
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    • pp.69-92
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    • 1996
  • The purpose of study was : 1) to analyze the trend of research on the family with chronically ill children in Korea, 2) to suggest direction for future study on the family with chronically ill children, and contributing to the use of intervention in family nursing practice. Research studies on the family with chronically ill children were selected from the Korean Nusre, the Korean Nurses' Academic Society Journal, and from dissertations, which were conducted between 1975 and 1995. The total numbers of the studies were 35. These studies were analyzed for 1)time of publication or presentation, 2)research design, 3)characteristics of subjects, 4) type of chronic disease, 5)main concepts, 6)measurement tool, 7) the sis for a degree or nondegree, 8) result of correlational studies. The findings of the analysis were as follows : 1) The numbers of studies on the family with chronically ill children have increas rapidly the early 1990's. In research design, the numbers of survey research studies were the highest. Especially, the most frequently research design was the correlational survey. There were 19 correlational studies(25.7%) during the early 1990's. 2) The subjects in 16 studies(45.7%) were mother of chronically ill children and, in 8 studies (22.9% ) were their parents. 3) In most types of chronic diseases, there were 14 hematooncologic disease(32.6%) and 14 hadicapped children (32.6% ). 4) Frequently used research concepts were stress, degree of coping or way of coping, social support, parents' support, family functioning, intensity of family and family adaptation. 5) Acceding to the results of correlational studies, the more family stress was higher the more degree of coping, family functioning, intensity of family and degree of family adaption was lower. The more degree of social support was higher the more stress was lower and degree of coping, family functioning and intensity of family was higher. The more family functioning was higher the more intensity of family and family adaptation was higher. 6) 24 researches on the family with chronically ill children were done for a thesis for a degree and 11 were nondegree research studies. The following suggestions are made based on the above findings : 1) The pattern of these studies related to the family with chronically ill children in domain of Nursing need to be compared with trend in other domains. 2) More replicated research on the family with chronically ill children is needed to develop family nursing intervention and prove the effect of that and more qualitative research on the family with chronically ill children is needed to comprehensive indepth the family with chronically ill children. 3) Further research on the family with chronically ill children is needed to verify subjects and type of chronic disease, develop applicable measurement tools in Korea and identify relation between other concepts. 4) Family nursing researchers should make an effort to apply research result in various clinical settings and community settings, and try to carry out not only team research with clinical nurse but also other multidisciplinary researcher related to the family.

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Analysis of articles published in the Journal of Korean Academy of dental technology (대한치과기공학회지 게재논문의 연구동향 분석)

  • Kim, Hee-Jung
    • Journal of Technologic Dentistry
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    • v.34 no.1
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    • pp.45-56
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    • 2012
  • Purpose: This study reviews the recent trend of Korean Academy of dental technology research. The data examined are the articles published in the Korean Journal of Korean Academy of dental technology from 1979 to 2011. Methods: The data are retrieved through the internet database Korean Academy of dental technology. The number of paper published is 540, published in 33 volumes of the journal. This study examines research methods, subjects, and author information. Results: Among the 540 articles collected, 422 are Original papers, 106 Clinical Technical Papers, 12case Other papers. 235 are experimental studies. Most experimental studies(235) have examined the ceramic(Porcelain) parts(117). The sole author of 315, co-author of 225 appeared. In turn of dental technicians, and students appeared. Conclusion: The study is to present basic data for research and to indicate the direction of their study in the future.

Recent Trends in Oriantal Medical Treatment for Tinnitus (이명(耳鳴)의 한방치료에 대한 최신 연구 동향)

  • Jung, Hyun-A
    • Journal of Haehwa Medicine
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    • v.20 no.1
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    • pp.143-151
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    • 2011
  • Objectives : This study is to research the trend of the oriantal medical treatment for tinnitus and to establish the hereafter direction for the study on oriantal medical treatment for tinnitus. Methods : We reviewed the domestic articles published last eleven years(2000- 2010). Results : We have searched 21 articles in 5 journals of korean oriental medical ophthalmology &dermatology, korean acupuncture & moxibustion, korean oriental medicine, oriental physiology & pathology, sasang constitutional medicine. 1. There were the most research done 2006. They have 5 articles. In other years there were 3 or less articles. 2. The pattern of study was as follow: the consideration of documents were 5, clinical trials were 6, case studies were 8 and the others were 2. the rate of case studies were increased. 3. After mid 2000s, there were more studies of new research method appearing. Conclusions : The oriental medical treatment already effective for tinnitus. But we need more studies about various kind of oriental medical treatment for tinnitus.

Domestic and Foreign Research Trend on the Pediatric Chuna Treatment (소아 추나에 대한 국내·외 연구 동향)

  • Lee, Jin Hwa;Han, Jae Kyung;Kim, Yun Hee
    • The Journal of Pediatrics of Korean Medicine
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    • v.29 no.4
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    • pp.67-76
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    • 2015
  • Objectives The purpose of this review is to investigate the domestic and foreign studies of pediatric Chuna treatment and propose the directions of future studies and clinical applications. Methods We searched for the study at RISS, KISS, DBPIA, Pubmed, CNKI by keywords, '추나', 'Osteopathic', 'Chiropractic', 'Manipulation', '推拿', '導引', '按摩', After 2010. Results 1. Selected 3 domestic studies were categorized as 1 survey study and 2 case reports. Selected 41 foreign studies from Pubmed were categorized as 15 systemic reviews, 8 survey studies, 12 case reports and 6 control studies. Selected 82 foreign studies from CNKI were categorized as 10 systemic reviews, 22 case reports and 50 control studies. 2. 2 clinical domestic studies researched on idiopathic Scoliosis. The foreign clinical studies from Pubmed are 18 cases, and those studies were categorized into Premature baby care (3), Infant colic (2), ADHD (2), Congenital talipes equinovarus (1), Somatic dysfuntion (1), Nonsynostotic occipital plagiocephaly (1), Conversion disorder (1), Lower back pain (1), Chronic bilateral dorsal foot pain and stiffness (1), plantar fasciitis (1), Migraine headaches (1), Cyclic vomiting syndrome (1), Acute otitis media (1) and Cerebral palsy (1). The other 72 foreign clinical studies were from CNKI, and they studied 39 different diseases. Systematically, they studied about digestive diseases (25), respiratory diseases (20), fever (6), musculoskeletal diseases (5), nervous system diseases (5), dermatology diseases (2) and other disease states. The Chuna treatment was used in variety of studies. 3. 2 clinical domestic studies adopted techniques of Osteopathy Chuna. The foreign clinical studies from Pubmed adopted techniques of Osteopathic manipulation (10) and Chiropractic manipulation (8). The other foreign clinical studies from CNKI adopted techniques of Acupressure (69), Abdominal manipulation (23), Spinal manipulation (21), Thoracic manipulation (11), Traction manipulation (2), Muscular manipulation (2), Squeezing Sha manipulation (1), Spine correction (1), Joint manipulation (1) and Fascia manipulation (1). Conclusions In addition to musculoskeletal disorders, variety of pediatric diseases could be treated with Chuna treatment instead of acupuncture.

Research Trend Analysis of Research Published in the Journal of Dental Hygiene Science from 2011 to 2020

  • Lee, Sun-Mi;Seong, Mi-Gyung;Moon, Hee-Jung;Son, Jung-Hui
    • Journal of dental hygiene science
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    • v.22 no.3
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    • pp.131-138
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    • 2022
  • Background: The purpose of this study was to analyze research trends in articles published in the Journal of Dental Hygiene Science over the past decade. Methods: From 2011 to 2020, 653 studies were reviewed using a keyword analysis. Contents such as academic classification, research type, research method, research topic, data collection method, data analysis method, and financial support were analyzed. Results: Analysis by school type showed 34.2% of clinical dental hygiene studies, 23.3% of educational dental hygiene studies, 22.8% of basic dental hygiene studies, 10.0% of other field studies, and 9.8% of social dental hygiene studies. By type of study, quantitative studies were the most common at 69.5%. Regarding data collection methods, 45.8% of the studies that used surveys were the most common. The subjects of the study were 20.1% experimental studies, 15.6% general adults, and 15.0% dental hygienists. Regarding the data analysis method, 49.3% of the studies that conducted frequency analysis were the most common. The total number of keywords was 2,390, with 107 (4.48%) being 'dental hygienists.' Next, oral health was the most common with 67 (2.80%) articles, followed by 31 for the elderly (1.30%), 25 for dental hygiene students (1.05%), and 24 for stress (1.00%). Conclusion: For academic development of dental hygiene, it is necessary to explore the diversity of academic topics based on the results of this study. It is necessary to find a way to spread the research results so that the published research can be used for the academic development of dental hygiene.