The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
권호 표지
DOI QR코드

DOI QR Code

A Systematic Review of Herbal Medicine in the Treatment of Cirrhotic Ascites

  • Kim, Seungmo (Department of Korean Internal Medicine of Hepatology, College of Korean Medicine, Daegu Haany University) ;
  • Lee, Yuri (Department of Korean Internal Medicine of Hepatology, College of Korean Medicine, Daegu Haany University) ;
  • Cho, Nakyung (Department of Korean Internal Medicine of Hepatology, College of Korean Medicine, Daegu Haany University) ;
  • Choi, Hongsik (Department of Korean Internal Medicine of Hepatology, College of Korean Medicine, Daegu Haany University) ;
  • Kim, Kyungsoon (Department of Korean Internal Medicine of Hepatology, College of Korean Medicine, Daegu Haany University)
  • Received : 2021.09.28
  • Accepted : 2021.11.05
  • Published : 2021.12.01
Download PDF
⟨ Previous Next ⟩

Abstract

Objectives: The purpose of this study was to investigate the trend in the research on cirrhotic ascites using t herbal medicine. Methods: This review was conducted using six electronic databases(NDSL, KMBASE, Koreantk, KISS, KISTI, KoreaMed) with no restriction in year. The search term was 'liver cirrhosis', 'ascites', or 'cirrhotic ascites', 'herbal medicine', 'traditional Chinese medicine', and 'randomized clinical trial', and there was no restriction in year. The searched studies were analyzed according to the type of research. Results: After scanning the titles and abstracts, 13 articles were ultimately included. Of the outcome measures of 13 studies, effective rate, liver function test, and ascites regression time were included in the meta-analysis, which showed that the effective rate of herbal medicine-supportive treatment combination therapy was 1.27 times higher than that of supportive treatment alone, and the difference was statistically significant. Conclusions: We analyzed the trends of cirrhotic ascites treatment in herbal medicine through this review. It is necessary to conduct further studies, such as well-designed clinical trials based on the results from experimental research.

Keywords

Acknowledgement

This study was supported by the 2018 National Research Foundation of Korea grant funded by the Korean government (Ministry of Science and ICT) (No. 2018R1A5A2025272).

References

  1. Korean Statistical Information Service (KOSIS) Annual report on the cause of death statistics 2017 [Internet] Daejeon: Statistics Korea; [cited 2021 Jul 04]. Available from: http://kosis.kr/search/search.do?query=%EC%82%AC%EB%A7%9D%EC%9B%90%EC%9D%B8.
  2. Bacon BR. Cirrhosis and Its complications. In: Kasper, DL, Fauci AS, Hauser S, Longo D, Jameson JL & Loscalzo J. Harrison's Principles of Internal Medicine. 19th ed. NewYork: McGraw-Hill. 2017:2943-4.
  3. Kim, K.A. (2009). Management of the Patients with Liver Cirrhosis. Clinical and Molecular Hepatology. 15(3s), 276-80.
  4. Bianchi, G., Marchesini, G., Nicolino, F., Graziani, R., Sgarbi, D., Loguercio, C., et al. (2005). Psychological status and depression in patients with liver cirrhosis. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 37(8), 593-600. https://doi.org/10.1016/j.dld.2005.01.020
  5. Korean Association for the Study of the Liver (KASL) (2018). KASL clinical practice guidelines for liver cirrhosis: Ascites and related complications. Clinical and molecular hepatology, 24(3), 230-277. https://doi.org/10.3350/cmh.2018.1005
  6. D'Amico, G., Garcia-Tsao, G., & Pagliaro, L. (2006). Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. Journal of hepatology, 44(1), 217-231. https://doi.org/10.1016/j.jhep.2005.10.013
  7. Professor Group of Korean Internal Medicine of Liver system. Korean Internal Medicine of Liver system. 6th ed. Seoul: Nado. 2015: 327-54.
  8. Lee, C.H., Kim, B.S., Kim, K.S., Kwak, M.A., & Kim, S.M., (2018). Effects of Electroacupuncture on the Muscle Cramps of Liver Cirrhosis Patients: A Randomized Controlled Study. The Journal of Internal Korean Medicine. 39(4). 511-519. https://doi.org/10.22246/jikm.2018.39.4.511
  9. Bae, J., Joo, S., An, S., Jang, E., Kim, Y., & Lee, J. (2018). A Case Study of Two Alcoholic Liver Cirrhosis Patients. The Journal of Internal Korean Medicine, 39(2), 176-183. https://doi.org/10.22246/jikm.2018. 39.2.176
  10. Kim, E., Bae, I., & Shin, G. (2017). A Case Report of Dyspepsia in a Patient with Liver Cirrhosis and Pancytopenia. The Journal of Internal Korean Medicine, 38(5), 592-599. https://doi.org/10.22246/jikm.2017.38.5.592
  11. Kang, K.W., Lee, J.H. (2016). A Case of Alcoholic Liver Cirrhosis Treated with Injinoryeong-san. The Journal of Internal Korean Medicine, 37(1), 135-142.
  12. Kim, S. Y., Park, J. E., Seo, H. J., Lee, Y. J., Jang, B. H., Son, H. J., et al. (2011). NECA's guidance for undertaking systematic reviews and meta-analyses for intervention. Seoul: National evidence-based healthcare collaborating agency.
  13. Huseini, H. F., Alavian, S. M., Heshmat, R., Heydari, M. R., & Abolmaali, K. (2005). The efficacy of Liv-52 on liver cirrhotic patients: a randomized, double-blind, placebo -controlled first approach. Phytomedicine : international journal of phytotherapy and phytopharmacology, 12(9), 619-624. https://doi.org/10.1016/j.phymed.2004.10.003
  14. Liao, W. Z., & Zeng, Y. S. (2012). Clinical Observation of Self-designed Chinese Medicinal Boiling Agent in Treatment of Hepatocirrhosis ascites(自拟中药煮散剂治疗肝硬化腹水的临床观察). Chinese Journal of General Practice(中华全科医学), 10(3), 432-433. http://www.cqvip.com/qk/87341a/201203/41075263.html
  15. Liao, W. Z. (2015). Chinese Medicine Powder for Boiling and Honeyed Pill Combined with Antiviral Medicine in the Treatment of Hepatitis B Liver Cirrhosis Ascites(中药煮散, 蜜丸联合抗病毒药物治疗乙肝肝硬化腹水). Chinese Medicine Modern Distance Education of China(中国中医药现代远程教育), (24), 33-35. http://www.cqvip.com/qk/87077x/201524/667845150.html
  16. Liu, X. W. (2012). Clinical analysis of 67 cases of liver cirrhosis peritoneum with Chinese medicine(中药辅治肝硬化腹水 67 例临床分析). Chin J of Clinical Rational Drug Use(临床合理用药杂志), 5(34), 74-75. http://www.cqvip.com/qk/88922x/201234/43907073.html
  17. Liu, X. M., & Li, H. Q. (2017). Observation on the Effect of Traditional Chinese Medicine in Hepatocirrhosis with Wuling Powder Combined with Peritoneal Acupuncture (中药经方五苓散联合腹针疗法治疗肝硬化腹水疗效观察). Digest of the World Core Medical Journals. Clinical Neurology(世界最新医学信息文摘(电子版), (33), 108-113. https://www.cnki.com.cn/Article/CJFDTotal-WMIA201733079.htm
  18. Qi, Y. (2017). Clinical Effect of Traditional Chinese Medicine in the Treatment of Liver Cirrhosis Ascites(中医中药治疗肝硬化腹水的临床效果观察). China Continuing Medical Education(中国继续医学教育), 9(33), 105-106. http://www.cqvip.com/QK/71296X/201733/674355917.html
  19. Shen, F. M., Wang, C. Y., & Song, C. Y. (2011). Treatment of Hepatiosclerotic ascites with Western medicine in 32 cases(健脾利水中药配合西药治疗肝硬化腹水 32 例). Shaanxi Journal of Traditional Chinese Medicine(陕西中医), 32(9), 1110-1111. http://www.cqvip.com/qk/94970x/201109/39302503.html https://doi.org/10.3969/j.issn.1000-7369.2011.09.003
  20. Miao, S. H, Wu, Z. W., & Zhu, H. Y. (2018). Clinical analysis of spleen-strengthening medicine with western medicine in the treatment of cirrhosis of liver ascites(健脾利水中药配合西药治疗肝硬化腹水的临床疗效分析). Journal of Contemporary Clinical Medicine(当代临床医刊), 31(2), 3752-3753. http://www.cqvip.com/qk/96520a/201802/7000516632.html
  21. Yao, S. Y. (2009). The study of traditional Chinese medicine cures the ascites of liver cirrhosis(中药方剂治疗肝硬化腹水初探). Journal of Liaoning University of Traditional Chinese Medicine(辽宁中医药大学学报), 11(5), 102-103. https://en.cnki.com.cn/Article_en/CJFDTotal-LZXB200905056.htm
  22. Yao, R. (2017). Clinical Observation on Treatment of Hepatitis B Hepatopancreatic ascites with Traditional Chinese Medicines and Western Medicines(中药消臌汤联合西药治疗乙肝肝硬化腹水的临床观察). Journal of Aerospace Medicine(航空航天医学杂志), 28(8), 1007-1009. http://www.cqvip.com/qk/90537a/201708/673295737.html
  23. Yu X.F., Lin, L. & Song, Y. (2014). Clinical Observation of Traditional Chinese Medicine by Many Ways and Western Medicine Treating Liver Cirrhosis Ascites. Journal of Emergency in Traditional Chinese Medicine, 23(5), 1692-1694. http://www.cqvip.com/qk/89565x/201401/48396693.html
  24. Zhang, B. H. (2008). Curative Effect on Diuretic and Compound Chinese Medicine for 30 Cases of Hepatitis Cirrhosis Ascites(利尿剂联合复方中药治疗肝硬化腹水30例疗效观察). Modern Diagnosis and Treatment(中国现代医生), 46(4), 5-7. http://www.cqvip.com/qk/60066a/2008004/26697578.html
  25. Zhao, Z. S., Chen, H. B., & Lin, Z. P. (2016). Clinical Effect Observation of Treating Liver Cirrhosis Ascites with Traditional Chinese Medicine Combined with Western Medicine. Modern Diagnosis and Treatment, 27(6), 1015-1017.