• Journal of Science Education
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• v.38 no.2
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• pp.317-330
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• 2014

The perception of pre-service teachers who participated as liaison teachers in the gifted education organization's different operating styles and the differences in the thoughts of these teachers were analyzed in this study. The inquiry survey was performed for 74 liaison teachers who had participated in the observational activities in the university annexed science gifted education center and the dormitory based gifted students education center supported by education of administration in Chungbuk Province. The individual in-depth interview was performed with 7 teachers based on the analyzed data. The perception of pre-service teachers who participated in as liaison teachers in the university annexed science gifted education center and the dormitory based gifted students education center was different from important element of the gifted and qualification of the teacher for gifted education. It was revealed that the differences between the education parts, education schedule and education methods of two the education centers, which were performed during the semester, influenced the perception of pre-service teachers who participated as the liaison teachers. The necessity of the systematic training on the observational skills and class contents were suggested as the essential support system for liaison teachers. The results of the study indicate that the gifted education organizations operating styles, the activities of liaison teachers, and pre-service teacher training program for gifted education emphasizes the long term actual guide experience at the education field for the gifted.

• Journal of Chest Surgery
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• v.25 no.11
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• pp.1318-1326
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• 1992

Backgroud. To determine the influence of age at operation upon surgical outcome in patients with isolated secundum atrial septal defect, retrospective clinical analysis was done. Material and method. From June, 1976 to December, 1991, 146 patients, 63 male and 83 female patients ranging in age from 13 months to 56 years, were operated on for isolated secundum atrial septal defect. The patients were divided into 3 groups according to their age at operation: Group I [<20 years old], 91 patients[62.3%]; Group II [21 to 40 years old], 44 patients[30.1%]; GroupIII[>41 years old], 11 patients[7.6%]. Significant differences in clinical features, hemodynamic function, early and late results between age groups were speculated. Results. One hundred thirty-one patients[89.6%] were symptomatic at the time of operation, the most common symptoms being dyspnea on exertion, recurrent respiratory infection, palpitation and chest pain. Patients in NYHA class III or IV were 3.3% in group I, 25% in groupIII, and 54.5% in group Ill. Hemodynamic data was available for 138 patients [94.5%]. Significant pulmonary hypertension [MPA systolic pressure $^3$ 40mmHg] was noted in 22 patients [15.9%]. Patients with pulmonary vascular disease [Rp/Rs>1.25] were 2% in group I, 7.3% in group Il, and 9.1% in groupIII. But there were no significant differences between the age groups in the size of the shunt or the ratio of pulmonary to systemic flow. Atrial septal defects were closed with direct suture in 144 patients and patch repair was performed in 2 patients with high defect. Atrial arrhythmia [8.2%] was the most common postoperative complication. The mean [LSD] duration of follow-up in all patients was 16$\pm$22 months [range, 1~96 months]. Functional result was excellent regardless of the age groups. During follow-up period, late cardiovascular events were arrhythmia [7 cases], reoperation for recurrent ASD [2 cases], and premature late death due to bacterial endocarditis [1 case]. Incidence of preoperative and late atrial fibrillation was significantly higher in older age group. Conclusion. Age at operation is one of the most important predictor of early and late surgical outcome with its impact on the following factors : 1] hemodynamic alterations and ventricular dysfunction due to longstanding volume and pressure overload, 2] pulmonary vascular disease, and 3] atrial arrhythmia including atrial fibrillation as a result of atrial dilatation. Therefore, among patients with surgically repaired atrial septal defects, those operated on over the age of 20 require careful supervision on the long-term basis.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.11
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• pp.1837-1847
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• 2020

Objective: To evaluate the pancreatic differentiation potential of α-1,3-galactosyltransferase knockout (GalTKO) pig-derived bone marrow-derived mesenchymal stem cells (BM-MSCs) using epigenetic modifiers with different pancreatic induction media. Methods: The BM-MSCs have been differentiated into pancreatic β-like cells by inducing the overexpression of key transcription regulatory factors or by exposure to specific soluble inducers/small molecules. In this study, we evaluated the pancreatic differentiation of GalTKO pig-derived BM-MSCs using epigenetic modifiers, 5-azacytidine (5-Aza) and valproic acid (VPA), and two types of pancreatic induction media - advanced Dulbecco's modified Eagle's medium (ADMEM)-based and N2B27-based media. GalTKO BM-MSCs were treated with pancreatic induction media and the expression of pancreas-islets-specific markers was evaluated by real-time quantitative polymerase chain reaction, Western blotting, and immunofluorescence. Morphological changes and changes in the 5'-C-phosphate-G-3' (CpG) island methylation patterns were also evaluated. Results: The expression of the pluripotent marker (POU class 5 homeobox 1 [OCT4]) was upregulated upon exposure to 5-Aza and/or VPA. GalTKO BM-MSCs showed increased expression of neurogenic differentiation 1 in the ADMEM-based (5-Aza) media, while the expression of NK6 homeobox 1 was elevated in cells induced with the N2B27-based (5-Aza) media. Moreover, the morphological transition and formation of islets-like cellular clusters were also prominent in the cells induced with the N2B27-based media with 5-Aza. The higher insulin expression revealed the augmented trans-differentiation ability of GalTKO BM-MSCs into pancreatic β-like cells in the N2B27-based media than in the ADMEM-based media. Conclusion: 5-Aza treated GalTKO BM-MSCs showed an enhanced demethylation pattern in the second CpG island of the OCT4 promoter region compared to that in the GalTKO BM-MSCs. The exposure of GalTKO pig-derived BM-MSCs to the N2B27-based microenvironment can significantly enhance their trans-differentiation ability into pancreatic β-like cells.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.39 no.2
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• pp.106-117
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• 2006

We measured the concentrations of organic matter and metallic elements (Al, Fe, Cr, Mn, Ni, Cu, Zn, As, Cd, Pb and Hg) in the surface sediments of Masan Harbor (in the southern sea, Korea) to evaluate the geochemical characters of sediment and the pollutions by organic matter and metallic elements. The mean grain size of the surface sediments in the study area ranged from $5.6{\phi}$ to $7.8{\phi}$, indicating silt sediment. The water content of the surface sediments exceeded 60% except at some stations. The contents of ignition loss (IL), total organic carbon (TOC) and total nitrogen (TN) ranged from 7.2-14.3%, 1.2-3.2%, and 0.10-0.28%, respectively. Based on the C/N ratios, the organic matter in the surface sediments of Masan Harbor may originate from terrigenous sources including fluvial inputs (mainly sewage in urban areas). The chemical oxygen demand (COD) and acid volatile sulfide (AVS) ranged from $11.3-29.9\;mgO_2/g\;dry$ and 0.20-4.47 mgS/g dry, respectively, and low concentrations were observed near a shipping route. In addition, the concentrations of metallic elements showed large spatial variations in Masan Harbor and the distributions of metallic elements were also comparable to those of organic matter. This implies that the distributions of organic matter and metallic elements in the surface sediments of Masan Harbor are mainly controlled by biogenic matter and artificial action (mainly dredging). In addition, we calculated the enrichment facto. (EF) and geoaccumulation index (Igeo) in order to evaluate pollution by metallic elements. The enrichment of metallic elements relative to Al was three to eighteen times higher at the study sites, compared to levels in the Earth's crust except for Fe, Ni and Mn. In addition, the Igeo class indicated that the surface sediments in the study area were moderately to strongly polluted in terms of metallic elements.

• Journal of Elementary Mathematics Education in Korea
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• v.13 no.1
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• pp.97-114
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• 2009

The purpose of this study was to investigate the effects of digital mathematics textbook on spatial abilities, interest and achievement of 6th graders. For this, research questions were set as follow: A. Is there any difference in cognitive ability in the space perception test between the experimental group and the control group. B. What distinctive attributes exist between the experimental group and the control group in the Spatial abilities? C. Is there any difference in learners' interest and achievement between the experiment group and the control group. To investigate the research questions, two classes of 6th grade children were selected from an elementary school in Daejeon and assigned one as experimental group and the other as control group. The experimental group studied mathematics using Digital Textbooks under an individual PC environment while the control group studied using the existing book-type textbooks. The following results and conclusions were obtained from the research. First, the effect of the Digital Textbooks on children's mathematics achievement was not statistically meaningful even though there was some progress in children's achievement. Furthermore, it was not found that the usage of a Digital Textbooks consistently influenced improvement in the students' interest in mathematics. Second, there were some positive changes in the achievement of Spatial ability of the middle subgroup of pretest score in the experiment group. It can have some educational implication that the Digital Textbooks can affect positively to the middle group in mathematics achievement who dominated more than 50% of the class. Third, the number of correct answers was found to be somewhat higher than that of the control group in spatial reasoning items. This means that the learning environment with Digital Textbooks allow more opportunities for manipulating geometric objects physically and mentally. Therefore, It seems necessary to offer various resources such as digital contents for students' geometric learning. For future research, It is strongly recommended to fix the bugs of the digital textbook programs and to upgrade the operating system of the computer.

• Education of Primary School Mathematics
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• v.2 no.1
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• pp.53-64
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• 1998

Two different CAI programs have been developed to study the affect of CAI element for the types of learners'performance; (i) one is the 'CAI program 1' including the open questions for the fourth grade (the fourth period of the 'Time and Angle' in chapter 3 of the first term) of the mathematics class in the elementary school, and (il) the other is 'CAI program 2' for the existing methods. The fourth grade of Andong Songhyun elementary school has been chosen as the study subjects (243 learners), and the t-test and learners'interview have also been used to analysis the results of CAI programs. The CAI programs have only been used as the control variable. The developed CAI programs have been applied two different learners'groups to investigate the degree of performance among the superior, average, and inferior learners. For the superior group (p＜.0023) at the t＜3.2268 level and for the average group (p＜.0706) at the t＜1.8211 level the learner' group using CAI program 1 shows the higher performance compared with the learners' group using the CAI program 2, whereas fur the inferior group (p＜.8073) at the t＜.2458 level two programs did not show any difference. The learners interviews show that the superior and average groups have an interest for the open problems, whereas the inferior group do not shows an interest for the open problems. Thus, the CAI programs including the open questions (open fields, open evaluation) will be helped to the learners' group with the individual differences. Furthermore, it is expected that the CAI programs including the open questions as the mathematics and the program model of CAI can be used to develope the CAI program in future.

• Education of Primary School Mathematics
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• v.20 no.4
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• pp.253-266
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• 2017

The purpose of the study was to investigate the perceptions of Elementary school teachers on mathematics instruction. To do this, 7 test items were developed to obtain data on teacher's perception of mathematics instruction and 73 teachers who take mathematical lesson analysis lectures were selected and conducted a survey. Since the data obtained are all qualitative data, they were analyzed through coding and similar responses were grouped into the same category. As a result of the survey, several facts were found as follow; First, When teachers thought about 'mathematics', the first words that come to mind were 'calculation', 'difficult', and 'logic'. It is necessary for the teacher to have positive thoughts on mathematics and mathematics learning, and this needs to be stressed enough in teacher education and teacher retraining. Second, the reason why mathematics is an important subject is 'because it is related to the real life', followed by 'because it gives rise to logical thinking ability' and 'because it gives rise to mathematical thinking ability'. These ideas are related to the cultivating mind value and the practical value of mathematics. In order for students to understand the various values of mathematics, teachers must understand the various values of mathematics. Third, the responses for reasons why elementary school students hate mathematics and are hard are because teachers demand 'thinking', 'because they repeat simple calculations', 'children hate complicated things', 'bother', 'Because mathematics itself is difficult', 'the level of curriculum and textbooks is high', and 'the amount of time and activity is too much'. These problems are likely to be improved by the implementation of revised 2015 national curriculum that emphasize core competence and process-based evaluation including mathematical processes. Fourth, the most common reason for failing elementary school mathematics instruction was 'because the process was difficult' and 'because of the results-based evaluation'. In addition, 'Results-oriented evaluation,' 'iterative calculation,' 'infused education,' 'failure to consider the level difference,' 'lack of conceptual and principle-centered education' were mentioned as a failure factor. Most of these factors can be changed by improving and changing teachers' teaching practice. Fifth, the responses for what does a desirable mathematics instruction look like are 'classroom related to real life', 'easy and fun mathematics lessons', 'class emphasizing understanding of principle', etc. Therefore, it is necessary to deeply deal with the related contents in the training courses for the improvement of the teachers' teaching practice, and it is necessary to support not only the one-time training but also the continuous professional development of teachers.

• Korean Journal of Poultry Science
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• v.38 no.2
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• pp.97-104
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• 2011

We conducted a 10-month (March to October 2009) surveillance of Newcastle disease virus (NDV) in 13 slaughterhouses in Korea. NDV was isolated in 13.0%, 13.3%, 16.0%, and 10.8% of chicken farms, transport vehicles, hang rooms, and chilling water, respectively. Of NDV isolates from slaughterhouses, 37% were isolated in July. All NDV isolates were determined to be lentogenic viruses by RT-PCR-based pathotyping, and all NDV isolates had the $^{112}GKQGR/L^{117}$ motif at the cleavage site of the F protein. Phylogenetic analysis based on the hypervariable region of the F protein gene classified all 25 NDV isolates examined into genotype I within class II. Of these, 24 were clustered together with the NDV V4 strain, while the remaining isolate was placed in the cluster belonging to the NDV Ulster 2C strain. Our results indicate that lentogenic NDV was a high-frequency contaminant in the serial process of ranging live birds to slaughtering at slaughterhouses.

• Korean Journal of Veterinary Service
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• v.34 no.1
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• pp.45-54
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• 2011

This study was conducted to investigate the distribution of Salmonella spp. from pigs and cattle in slaughterhouse, the antimicrobial resistance pattern and the prevalence of resistance genes of isolates. A total of 640 fecal samples from pigs and cattle in slaughterhouse were collected for isolation of Salmonella spp.. Isolation rate was revealed as 15% in pigs and 1.6% in cattle. As result of serotyping, group B (56.6%) were identified as most common in pigs and cattle isolates, in order of group C (24.5%) and group E (15.1%). S. Typhimurium (50.9%) was most common serotype. The major serotypes were in order of S. Rissen and S. London (11.3%) and S. Riggil (7.6%). In antimicrobial test, all isolates were demonstrates susceptibility to nitrofurantoin. But isolates were revealed resistance other antibiotics in order of tetracycline (64.6%), streptomycin (68.3%), ampicillin and amoxicillin (56.3%) and spectinomycin (47.9%). With polymerase chain reaction, antimicrobial resistance gene strA (75.0%) and aadA1 (3.1%) were detected in streptomycin resistance isolates and tetA (94.3%) and tetB (11.3%) gene were detected in tetracycline resistant isolates, but tetG was not detected. Class 1 integron gene was detected in all Salmonella isolates.

• Proceedings of the Korea Water Resources Association Conference
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• 2007.05a
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• pp.97-105
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• 2007

수문학적 토양유형은 복잡하게 세분되어 있는 토양의 종류를 수문학적인 목적에 따라 단순화하기 위해 만든 것으로 미농무성 토양보전국에서 고안한 개념이다. 우리나라 토양을 이 방법으로 구분하고자 하는 몇번의 시도가 있으며 그 중 대표적인 것이 정 등(1995)이 분류한 수문학적 토양군이다. 이는 토양의 침투 투수특성에 대한 실측자료가 부족한 우리나라의 실정을 감안하여 토성속(textural family), 배수등급(drainage class), 불투수층(impermeable layer), 투수성(permeability)의 네가지 토양특성을 분류특성으로 하여 각각에 1-4점 범위로 점수를 매긴 후 합산한 점수를 기준으로 수문학적 토양유형을 분류하는 것이다. 최근에는 토양의 한계침투속도에 따라 수문학적 토양유형을 분류하고자 하는 시도가 있으며 본 논문에서는 새로운 방법으로 분류할 때 기존의 방법과 어떠한 차이가 있는지 비교하고자 하였다. 정 등(1995)의 분류방법은 개념상 몇가지 문제점을 안고 있다. 먼저 토양의 수리특성은 같은 토성속이라 하여도 토양생성 과정과 토지이용 방법에 따라 그 차이가 매우 큼에도 불구하고 이에 대해 고려하지 못하였으며 다음으로 지표유거가 많아 배수가 양호한 토양의 강우 유출을 과소평가한다. 또한 얕은 토심에 존재하는 불투수층이 존재하는 경우 토양의 수리특성에 관계없이 적은 양의 강우에도 유출이 발생하므로 별도의 제한인자로 간주하여야 한다. 토양의 한계 침투속도를 이용한 분류방법은 이러한 문제점을 상당 부분 개선할 수 있다. 토양의 한계침투속도를 산정하기 위해 현장에서 지표 한계침투속도와 투수속도를 측정하였으며 이 자료를 확장하여 해석하기 위해 입자특성을 이용한 Pedo Transfer Function을 개발하였다. 토심 50 cm 포화시 토양 투수성을 한계 침투속도로 가정하였으며 50 cm 이내에 암반층과 지하수위가 존재할 경우 투수성에 관계없이 D유형으로 분류하였다. 새로운 방법으로 분류한 결과 기존의 분류와 몇가지 차이점이 발견되었다. 가장 큰 차이는 대부분의 논토양이 느린 한계침투속도의 영향으로 D유형에 속한 것이다. 산림토양과 밭토양은 기존 방법과 마찬가지로 A, B유형이 많았으며 암반층을 고려하기 전에는 기존 분류에 비해 강우 유출 가능성이 적은 쪽으로 평가되었다. 그러나 암반층이 존재하는 토양을 고려한 결과 A 또는 B 유형에 속하던 상당수의 산림토양이 새로운 분류에서 D유형으로 분류되었다. 지표 유거가 많아 배수등급이 매우양호로 분류되던 토양은 정 등(1995)의 분류와 비교하여 대부분 강우 유출 가능성이 큰 쪽으로 조정되었다. 새로운 수문학적 토양유형을 이용할 경우 낮은 토심에서 암반층이 발견되는 산림토양이 분포한 유역이나 산림, 밭 등에 식질 토양이 많이 분포하는 유역에서는 기존의 방법을 이용하는 것보다 강우 유출량이 높게 평가될 것으로 판단된다. 앞으로 강우 유출량 실측자료와의 비교를 통해 지속적인 보정을 하여야 할 것이며 특히 불투수층의 존재시 일괄적으로 D유형으로 분류된 토양의 경우 깊이에 따라 C 또는 D 유형으로 세분하여 조정할 필요가 있다.