• Progress in Superconductivity
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• v.4 no.1
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• pp.1-9
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• 2002

Transferring single flux quanta across a Josephson junction at an exactly determined rate has made highly precise voltage measurements possible. Making use of self-shunted Nb-based SINIS junctions, programmable fast-switching DC voltage standards with output voltages of up to 10 V were produced. This development is now extended from fundamental DC measurements to the precise determination of AC voltages with arbitrary waveforms. Integrated RSFQ circuits will help to replace expensive semiconductor devices for frequency control and signal coding. Easy-to-handle AC and inexpensive quantum voltmeters of fundamental accuracy would be of interest to industry. In analogy to the development in the flux regime, metallic nanocircuits comprising small-area tunnel junctions and providing the coherent transport of single electrons might play an important role in quantum current metrology. By precise counting of single charges these circuits allow prototypes of quantum standards for electric current and capacitance to be realised. Replacing single electron devices by single Cooper pair circuits, the charge transfer rates and thus the quantum currents could be significantly increased. Recently, the principles of the gate-controlled transfer of individual Cooper pairs in superconducting A1 devices in different electromagnetic environments were demonstrated. The characteristics of these quantum coherent circuits can be improved by replacing the small aluminum tunnel Junctions by niobium junctions. Due to the higher value of the superconducting energy gap ($\Delta_{Nb}$ ＝ $7\Delta_{Al}$), the characteristic energy and the frequency scales for Nb devices are substantially extended as compared to A1 devices. Although the fabrication of small Nb junctions presents a real challenge, the Nb-based metrological devices will be faster and more accurate in operation. Moreover, the Nb-based Cooper pair electrometer could be coupled to an Nb single Cooper pair qubit which can be beneficial for both, the stability of the qubit and its readout with a large signal-to-noise ratio..

• Structural Engineering and Mechanics
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• v.86 no.4
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• pp.473-486
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• 2023

Nowadays, urban centers are increasingly vertical, making architects and engineers look for more efficient tools to analyze the effects of wind on tall buildings. Topology optimization can be used as an efficient tool for the design of bracing systems. Therefore, this work obtained the wind loads that act in the CAARC building, following the Brazilian standard NBR 6123/1988 and using Computational Fluid Dynamics. Four loading situations were considered, using the SIMP and BESO methods to optimize two-dimensional structures. A comparison between the SIMP and BESO methods is presented, showing the differences in the geometry of the solution found by both methods, the percentage variation in the objective function values and the dimensionless processing time. The solutions obtained through the loads obtained by the Brazilian standard are also compared with the numerical solutions obtained by CFD. The results show that the BESO method presented more rigid structures compared to the SIMP method. The bracing structures obtained with the SIMP method always present similar patterns in the distribution and quantity of bars, in contrast to the BESO method where no characteristic topology pattern was observed. It was concluded that even though the structures obtained by the BESO method presented greater stiffness, the SIMP method was less susceptible to the methodology used for the determination of wind loads. Additionally, it was evident the great potential that the combination topology optimization and computational wind engineering have in the design of bracing systems of high functional and aesthetic standards.

• Tuberculosis and Respiratory Diseases
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• v.86 no.3
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• pp.226-233
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• 2023

Background: Inactive or old, healed tuberculosis (TB) on chest radiograph (CR) is often found in high TB incidence countries, and to avoid unnecessary evaluation and medication, differentiation from active TB is important. This study develops a deep learning (DL) model to estimate activity in a single chest radiographic analysis. Methods: A total of 3,824 active TB CRs from 511 individuals and 2,277 inactive TB CRs from 558 individuals were retrospectively collected. A pretrained convolutional neural network was fine-tuned to classify active and inactive TB. The model was pretrained with 8,964 pneumonia and 8,525 normal cases from the National Institute of Health (NIH) dataset. During the pretraining phase, the DL model learns the following tasks: pneumonia vs. normal, pneumonia vs. active TB, and active TB vs. normal. The performance of the DL model was validated using three external datasets. Receiver operating characteristic analyses were performed to evaluate the diagnostic performance to determine active TB by DL model and radiologists. Sensitivities and specificities for determining active TB were evaluated for both the DL model and radiologists. Results: The performance of the DL model showed area under the curve (AUC) values of 0.980 in internal validation, and 0.815 and 0.887 in external validation. The AUC values for the DL model, thoracic radiologist, and general radiologist, evaluated using one of the external validation datasets, were 0.815, 0.871, and 0.811, respectively. Conclusion: This DL-based algorithm showed potential as an effective diagnostic tool to identify TB activity, and could be useful for the follow-up of patients with inactive TB in high TB burden countries.

• Korean Journal of Radiology
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• v.22 no.5
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• pp.714-724
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• 2021

Objective: To evaluate the value of ¹⁸F-fluorodeoxyglucose PET/MRI added to contrast-enhanced CT (CECT) in initial staging, assessment of resectability, and postoperative follow-up of biliary tract cancer. Materials and Methods: This retrospective study included 100 patients (initial workup [n = 65] and postoperative follow-up [n = 35]) who had undergone PET/MRI and CECT for bile duct or gallbladder lesions between January 2013 and March 2020. Two radiologists independently reviewed the CECT imaging set and CECT plus PET/MRI set to determine the likelihood of malignancy, local and overall resectability, and distant metastasis in the initial workup group, and local recurrence and distant metastasis in the follow-up group. Diagnostic performances of the two imaging sets were compared using clinical-surgical-pathologic findings as standards of reference. Results: The diagnostic performance of CECT significantly improved after the addition of PET/MRI for liver metastasis (area under the receiver operating characteristic curve [A_z]: 0.77 vs. 0.91 [p = 0.027] for reviewer 1; 0.76 vs. 0.92 [p = 0.021] for reviewer 2), lymph node metastasis (0.73 vs. 0.92 [p = 0.004]; 0.81 vs. 0.92 [p = 0.023]), and overall resectability (0.79 vs. 0.92 [p = 0.007]; 0.82 vs. 0.94 [p = 0.021]) in the initial workup group. In the follow-up group, the diagnostic performance of CECT plus PET/MRI was significantly higher than that of CECT imaging for local recurrence (0.81 vs. 1.00 [p = 0.029]; 0.82 vs. 0.94 [p = 0.045]). Conclusion: PET/MRI may add value to CECT in patients with biliary tract cancer both in the initial workup for staging and determination of overall resectability and in follow-up for local recurrence.

• Progress in Medical Physics
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• v.34 no.3
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• pp.23-32
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• 2023

Purpose: In radiomics analysis, to evaluate features, and predict genetic characteristics and survival time, the pixel values of lesions depicted in computed tomography (CT) and magnetic resonance imaging (MRI) images are used. CT and MRI offer three-dimensional images, thus producing three-dimensional features (Features_3d) as output. However, in reports, the superiority between Features_3d and two-dimensional features (Features_2d) is distinct. In this study, we aimed to investigate whether a difference exists in the prediction accuracy of radiomics analysis of lung cancer using Features_2d and Features_3d. Methods: A total of 38 cases of large cell carcinoma (LCC) and 40 cases of squamous cell carcinoma (SCC) were selected for this study. Two- and three-dimensional lesion segmentations were performed. A total of 774 features were obtained. Using least absolute shrinkage and selection operator regression, seven Features_2d and six Features_3d were obtained. Results: Linear discriminant analysis revealed that the sensitivities of Features_2d and Features_3d to LCC were 86.8% and 89.5%, respectively. The coefficients of determination through multiple regression analysis and the areas under the receiver operating characteristic curve (AUC) were 0.68 and 0.70 and 0.93 and 0.94, respectively. The P-value of the estimated AUC was 0.87. Conclusions: No difference was found in the prediction accuracy for LCC and SCC between Features_2d and Features_3d.

• International Commerce and Information Review
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• v.4 no.2
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• pp.253-277
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• 2002

Nowaday, the advanced technology in information and communication has been leading the dramatic change of transaction paradigm expansion from physical basis to electronic one. As we know, financial services support most of financial exchange between two business parties. So the expansion of electronic transaction paradigm affects to every financial institutions which provide financial services. Thus, financial institutions have accepted e-Finance systems and providing internet financial services to live in the competition. The purpose of this study is to contribute the qualitative enhancement of its customer service, rapid diffusion and accurate strategy establishment for e-Finance industry in the user side. Through the literature review and factor and reliability analysis, this study selects six diffusion factors such as efficiency of perceived e-Finance, reliability and safety of e-Finance in perceived e-Finance itself's characteristic; confidence, technical factors and the customer service quality of e-Finance system in perception on e-Finance System; inclination to innovation in the personal characteristic. According to result of hypothesis verification by using logistics regression analysis, technical factors and the customer service quality of e-Finance system in perception on e-Finance System and inclination to innovation in the personal characteristic gave statistically positive effect to the diffusion decision at the significant level 0.05 and 0.01. However efficiency of perceived e-Finance, reliability and safety of e-Finance in perceived e-Finance itself's characteristic didn't affect to diffusion decision and confidence of e-Finance system in perception on e-Finance System didn't have any statistical significancy. This study can be used as a basic material for the forward empirical study of diffusion factors in the user side and be able to apply to company and government policy making or embodiment, determination for customer service quality degree of financial institutions. But this study has some limitations like didn't touch satisfaction factors and its effect, only deal domestic customers and didn't use multi-regression analysis.

• Korean Security Journal
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• no.32
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• pp.7-32
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• 2012

This study aimed to evaluate the relative status using Analytic Hierarchy Process(AHP) on the spiritual factors of the security martial arts for the guards to perform the best security service. There were 540 participants who were students majored in security martial arts, workers for security and specialists of practical and theoretical security martial arts for this study. The exploratory and confirmatory factor analysis were carried out using the selecting data through literature reviews in the level of the factor-extraction about the spiritual characteristics. The specialists' survey was conducted on the relative status among factors using the spiritual concept structure based on the studied above. Selected data was calculated with SPSS 18.0 for windows, AMOS 5.0, and Expert Choice 2000 software. The conclusion can be made through those process above. First, 4 general factors and 20 detailed factors were found as the result of the factor exploration related to the spiritual characteristics of the security martial arts. The result which was verified on Construction validity of searched factors had stable figures on every standard. In other words, the participants for survey on this study "Spiritual characteristic concepts of the security martial arts" can be evaluated it is valid. The general factors of security martial arts' spirit were conceptualized with Psychological spirit, ethical spirit, martial art spirit, practical spirit through the naming process on the general factors of the security martial arts' spiritual characteristic concepts. The detailed factors of security martial arts' spirit were concentration, self-confidence, self-management, immersion, self-esteem in psychological spirit and sacrifice, justice, royalty, peace, sense of duty in ethical spirit and courtesy, toughness, defense, balance of mind and body, bravery in martial arts and responsibility, cooperation, modesty, determination, professionalism in practical spirit of security martial arts. That is, the conceptualization of security martial arts' spirit was verified that it had validity. Second, the hierarchical model of the security martial arts was composed with 4 superordinate concepts and 20 subordinate concepts. As the result of evaluating relative status based on Spiritual characteristics-hierarchy model, the impotance was proven in order of ethical spirit(.482), martial art spirit(.248), practical spirit(.188), psychological spirit(.083). Also the importance related to spiritual characteristics of security martial arts on subordinate concepts was proven in order of sacrifice(.252), courtesy(.110), sense of duty(.108), responsibility(. 073), royalty(.053), toughness(.052), justice(.049), defense(.038), professionalism(.038), determination(.035), cooperation(.029), self-confidence (.026), bravery(.025), self-esteem(.024), balance of mind and body(.023), peace(.019), concentration(.014), modesty(.013), self-management(.011), flow (.007). To sum up, the spiritual factor related to ethics such as sacrifice, justice, royalty, peace, sense of duty was the most important for the security martial arts.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.29 no.4
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• pp.329-341
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• 2011

The object of this paper is to compare the accuracy and the characteristic of various methods of solving the geodetic inverse problem for the geodesic lines which be in the standard case and special cases(antipodal, near antipodal, equatorial, and near equatorial situation) on the WGS84 reference ellipsoid. For this, the various algorithms (classical and recent solutions) to deal with the geodetic inverse problem are examined, and are programmed in order to evaluate the calculation ability of each method for the precise geodesic determination. The main factors of geodetic inverse problem, the distance and the forward azimuths between two points on the sphere(or ellipsoid) are determined by the 18 kinds of methods for the geodetic inverse solutions. After then, the results from the 17 kinds of methods in the both standard and special cases are compared with those from the Karney method as a reference. When judging these comparison, in case of the standard geodesics whose length do not exceed 100km, all of the methods show the almost same ability to Karney method. Whereas to the geodesics is longer than 4,000km, only two methods (Vincenty and Pittman) show the similar ability to the Karney method. In the cases of special geodesics, all methods except the Modified Vincenty method was not proper to solve the geodetic inverse problem through the comparison with Karney method. Therefore, it is needed to modify and compensate the algorithm of each methods by examining the various behaviors of geodesics on the special regions.

• Journal of Korea Technology Innovation Society
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• v.16 no.4
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• pp.1163-1186
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• 2013

Big science such as nuclear fusion accelerators shares the characteristic of requiring long-term and massive budget input, human power, and related state-of-the-art technology. Because big science, by nature, thus requires large-scale budgets and facilities yet harbors the possibility of failure, most projects are led by the government. When the actual circumstances are examined, however, such projects are often implemented through the formation of cooperative relations with small and medium businesses (SMBs) possessing outstanding technological capacity. On the other hand, the reality is that the entry of corporations into the business ecosystem of big science is not easy and that even those that have once entered big science likewise fail to find sales outlets for technology that they have developed following the supply of single items, thus leading their technological capacity to lie idle. Consequently, based on an awareness of the problem, the present study seeks to propose strategies for activating the business ecosystem of nuclear fusion and accelerators and to present alternatives regarding which policy tasks must be pursued first by using the analytic hierarchy process (AHP) technique. The present study derived the four policy alternatives of approach, care, expansion, and infrastructures in accordance with the results of empirical analysis to activate the business ecosystem of nuclear fusion and accelerators and analyzed their priority in terms of urgency and effectiveness, the results of which were, in this order: care-approach-expansion-infrastructures. The significance of such research results lie in presenting the policy direction when the government determines which policy task must be pursued first and implements strategies for the activation of the business ecosystem of nuclear fusion and accelerators with limited financial resources in the future.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.59 no.4
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• pp.391-397
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• 2014

Anthocyanins are water-soluble plant pigments that give rise to the red, purple, or blue colors observed in many crops. Especially purple pigment of colored rice represent biological activities has been an increased interest, due to the functional meal as a staple food. These health benefits have been attributed to antioxidant property of anthocyanin. However, there have been little genetic source for development of new and various colored rice variety. A recently developed new variety, 'Jungmo1020', showed an unique characteristic of blue color of rice grain hull. We identified the pigment petunidin-3-O-glucoside (Pt-3-G) as a major compound with a value of $176.3{\pm}2.3mg/100g$ (68.3%) from 80% MeOH with 1% HCl extracts by UPLC/MS/MS. The content of Pt-3-G in the extracts using a solvent of 100% MeOH with 1% HCl was the highest with the values of $183.8{\pm}2.5mg/100g$. In addition, these extracts showed excellent antioxidatative activities by DPPH and ABTs assay.