• 한국통신학회논문지
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• 제25권10A호
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• pp.1461-1472
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• 2000

이동 통신 가입자의 수가 폭발적으로 증가하는 상황에서 좋은 품질을 갖는 서비스를 제공하기 위해서는 새로운 Cell Planning 기법이 필요하다. 따라서 차세대 이동통신 시스템인 IMT-2000 망에서 적절한 Cell Planning 기법을 이용하여 계층 셀 구조를 구성하여만 정상적인 IMT-2000 서비스 제공이 가능할 것이다. 본 논문에서는 향후 서비스 될 제 3세대 이동통신 시스템인 IMT-2000(3GPP)의 권고안을 분석하여 셀 설계에 필요한 여러 파라미터를 살펴본다. 또한 IMT-2000 무선링크 분석을 위한 모델을 설정하고 수직적으로 유도함으로써 순방향과 역방향 링크 버짓, 시스템의 용량, Call Blocking 확률, Erlang Capacity, 셀 커버리지를 분석한다. 분석을 수행하는데 있어서 계층 셀의 구조와 사용자 수, 서비스의 종류, 지역 등 여러 가지 환경의 변화에 따른 설계의 방향을 제시하였다. 본 논문을 통해 IMT-2000 상용화 시 효율적인 Cell Planning 기법 제시 및 용량 극대화를 이룰 수 있을 것이다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제13권4호
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• pp.1941-1960
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• 2019

Unmanned aerial vehicles (UAVs), acting as mobile base stations (BSs), can be deployed in the typical fifth-generation mobile communications (5G) scenarios for the purpose of substantially enhancing the radio coverage. Meanwhile, UAV aided underlay device-to-device (D2D) communication mode can be activated for further improving the capacity of the 5G networks. However, this UAV aided D2D communication system is more vulnerable to eavesdropping attacks, resulting in security risks. In this paper, the D2D receivers work in full-duplex (FD) mode, which improves the security of the network by enabling these legitimate users to receive their useful information and transmit jamming signal to the eavesdropper simultaneously (with the same frequency band). The security communication under the UAV coverage is evaluated, showing that the system's (security) capacity can be substantially improved by taking advantage of the flexible radio coverage of UAVs. Furthermore, the closed-form expressions for the coverage probabilities are derived, showing that the cellular users (CUs)' secure coverage probability in downlink transmission is mainly impacted by the following three factors: its communication area, the relative position with UAV, and its eavesdroppers. In addition, it is observed that the D2D users or DUs' secure coverage probability is relevant to state of the UAV. The system's secure capacity can be substantially improved by adaptively changing the UAV's position as well as coverage.

• 한국정보통신학회논문지
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• 제9권6호
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• pp.1387-1394
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• 2005

본 논문에서는 다중 셀룰러 CDMA 환경에서 비균일 트래픽 특성을 가진 지능정보 처리를 위한 호 수락제어 기법을 제안하고, 이 기법의 성능을 분석한다. CDMA 시스템에서는 각 셀에서 동시에 통화할 수 있는 이동 가입자들의 수는 각 기지국이 수신하는 총 간섭량에 따라 제약을 받고, 또한 서비스 받는 이동 가입자의 수는 각 기지국마다 균일하지 않게 분포될 수 있다. 본 논문에서는 이러한 환경에서 비균일 트래픽 특성의 지능정보 처리용량을 높이기 위해 등가대역 개념을 이용한 호 수락 제어 기법을 사용하며, 신규 호의 차단율(blocking rate) 및 핸드오프 호의 절단율(dropping rate)을 감소시키기 위해 각 셀의 대역폭을 가변시켜 신규 호와 핸드오프 호를 처리한다. 실험결과 다중 셀룰러 CDMA 환경에 제안한 호 제어 기법을 적용함으로써 이동 가입자의 수용 용량을 증가시킬 수 있음을 확인하였다.

• 한국통신학회논문지
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• 제23권4호
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• pp.957-966
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• 1998

본 논문에서는 OS-COMA 셀룰라 시스템에서 추정된 SIR (signal-to-interference ratio) 값을 기반으로 하는 개선된 호 수락 제어(call admission control) 알고리즘을 제안하고 성능을 분석하였다. 제안된 알고리즘은 기지국에서 추정된 역방향 SIR 값에 따라 알고리즘에 의해 계산된 여유용량(residual capacity)을 호 수락 제어의 기준으로 하며, 여유용량은 시스탬의 통화품질 저하 확률(outage probability)을 일정 수준 이하로 유지하면서 추가로 허용 가능한 호의 수로 계산한다. 여유용량 계산 시 자기 셀 뿐만 아니라 인접 셀의 SIR 값을 참조하며 이때 인접 셀 간섭 결합계수 $\beta$를 사용한다. 본 논문에서는 자기 셀의 통화 부하량에 따라 $\beta$값을 가변한 개선된 알고리즘을 제안하고, 시스템의 통화 부하량에 따른 호차단확률(call blocking probability) 및 통화품질저하확률 성능을 시뮬레이션을 통해 분석하였다, 성능 평가를 위해 동일 부하(homogeneous load) 빛 밀집 부하(hot spot load) 조건을 고려했으며 개선된 알고리즘이 모든 부하량에서 기존의 알고리즘에 비해 성능이 우수함을 알았다. 특히 과부하 상황에서 통화품질저하확률이 일정한 값 이하로 유지되어 QoS(quality of service)를 확보할 수 있는 효과를 얻었다.

• 대한전자공학회논문지TC
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• 제45권2호
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• pp.60-66
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• 2008

본 논문에서는 직교주파수분할다중접속(Orthogonal Frequency Division Multiple Access) 하향링크 시스템에서 부반송파 별 채널 이득(channel gain)이 다름을 이용하여 시스템의 용량을 향상시킬 수 있는 핸드오버 기법을 제안한다. 제안하는 기법에서 핸드오버 중인 사용자는 소스 기지국(source base station)과 타겟 기지국(target base station)에서 할당 받은 부반송파 중 강한 채널이득을 가진 부반송파를 선택해 줌으로써 이득을 얻는다. 부반송파 선택 과정에서 탈락한 부반송파에 대한 정보는 기지국으로 피드백(feedback)되어 사용하지 않도록 하여 시스템 전체의 간섭(interference)량을 줄인다. 제안하는 기법은 핸드오버하고 있는 사용자의 오수신 확률을 22% 줄였으며, 이에 따라 시스템 전체의 전송률이 향상된다.

• Biotechnology and Bioprocess Engineering:BBE
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• 제3권1호
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• pp.1-5
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• 1998

One cervical cancer cell line, C9, carrying human papillomavirus type 18 (HPV18) genes that is one of the major etiologic concoviruses for cervical cancer was characterized. This cell line was further characterized for its capacity related to the epithelial cell proliferation, stratification and differentiation in reconstituted artificial epithelial tissue. The in vitro construction of three dimensional artificial cervical opithelial tissue has been engineered using C9 epithelial cancer cells, human foreskin fibroblasts and a matrix made of type I collagen by organotypic culture of epithelial cells. The morphology of paraffin embedded artificial tissue was examined by histochemical staining. The artificial epithelial tissues were well developed having multilayer. However, the tissue morphology was similar to the cervical tissus having displasia induced by HPV infection. The characteristics of the artificial tissues were examined by determinining the expression of specific marker proteins. In the C9 derived artificial tissues, the expression of EGF receptor, as epithelial proliferation marker proteins for stratum basale was observed up to the stratum spinosum. Another epithelial proliferation marker for stratum spinosum, cytokerations 5/6/18, were observed well over the stratum spinosum. For the differentiation markers, the expression of involucrin and filaggrin were observed while the terminal differentiation marker, cytokeratins 10/13 was not detected at all. Therefore the reconstituted artificial epithelial tissues expressed the same types of differentiation marker proteins that are expressed in normal human cervical epithelial tissues but lacked the final differentiation capacity representing characteristics of C9 cell line as a cancer tissue devived cell line. Expression of HPV18 E6 oncoprotein was also observed in this artifical cervical opithelial tissue though the intensity of the staining was weak. Thus this artificial epithelial tissue could be used as a useful model system to examine the relationship between HPV-induced cervical oncogenesis and epithelial cell differentiation.

• Toxicological Research
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• 제17권
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• pp.271-280
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• 2001

We report on the applicability oj a method recently developed in our laboratory for measuring the antioxidant potential of isolated chemicals and extracts derived from natural products. Peroxyl radicals generated by thermal homolysis of 2,2'-azobis-amidinopropane (ABAP) oxidize $\alpha$-keto-${\gamma}$-methiolbutyric acid (KMBA) to ethylene, which is monitored by gas chromatography. Inhibition of ethylene formation in the presence of antioxidants that compete with KMBA for peroxyl radicals is the basis of the Total Oxyradical Scavenging Capacity Assay (TOSCA; Winston et al., 1998). Antioxidative activities of water-soluble extracts of American green tea, the anti-hepatotoxic flavonolignan from milk thistle (Silybum marianum) silybin, Ginkgo biloba extract EGb 761, and a series of naturally occuring sesquiterpene lactones (all ger-macranolides found in in fungi, liverworts, and plants) were studied. The specific TOSC value per $\mu$M silybin was 5.2, which is essentially comparable to that of Trolo $x^{ⓡ}$, a water-soluble vitamine E analog. Tea and Ginkgo extracts exhibited potent peroxyl radical scavenging capacity with values, respectively of =1700 and 1000 $\mu$mols Trolo $x^{ⓡ}$ equivalent per gram dry matter. The known anti-inflammatory activity of some germacranolides prompted study of their antioxidant capacity. None of the lactones exhibited antioxidant capacity toward peroxyl radicals comparable to Trolo $x^{ⓡ}$; costunilide, the most lipophilic, had a TOSC value = to glutathione. The potential role of peroxyl radicals in lipidperoxidation, other cellular damage, and var-ious disease states suggest a possible preventive role for silybin, green tea and Ginkgo biloba in oxidative stress caused by these free radical species.ecies.

• Toxicological Research
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• 제26권4호
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• pp.321-327
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• 2010

The ability of 80% ethanol extracts from five medicinal plants, Aralia continentalis, Paeonia suffruticosa, Magnolia denudata, Anemarrhena asphodeloides, and Schizonepeta tenuifolia, to neutralize hydroxyl radical, peroxyl radical and peroxynitrite was examined using the total oxyradical scavenging capacity (TOSC) assay. Peroxyl radical was generated from thermal homolysis of 2,2'-azobis(2-methylpropionamidine) dihydrochloride (ABAP); hydroxyl radical by an iron-ascorbate Fenton reaction; peroxynitrite by spontaneous decomposition of 3-morpholinosydnonimine N-ethylcarbamide (SIN-1). The oxidants generated react with $\alpha$-keto-$\gamma$-methiolbutyric acid (KMBA) to yield ethylene, and the TOSC of the substances tested is quantified from their ability to inhibit ethylene formation. Extracts from P. suffruticosa, M. denudata, and S. tenuifolia were determined to be potent peroxyl radical scavenging agents with a specific TOSC (sTOSC) being at least six-fold greater than that of glutathione (GSH). These three plants also showed sTOSCs toward peroxynitrite markedly greater than sTOSC of GSH, however, only P. suffruticosa revealed a significant hydroxyl radical scavenging capacity. Seven major active constituents isolated from P. suffruticosa, quercetin, (+)-catechin, methyl gallate, gallic acid, benzoic acid, benzoyl paeoniflorin and paeoniflorin, were determined for their antioxidant potential toward peroxynitrite, peroxyl and hydroxyl radicals. Quercetin, (+)-catechin, methyl gallate, and gallic acid exhibited sTOSCs 40~85 times greater than sTOSC of GSH. These four components also showed a peroxynitrite scavenging capacity higher than at least 10-fold of GSH. For antioxidant activity against hydroxyl radical, methyl gallate was greatest followed by gallic acid and quercetin. Further studies need to be conducted to substantiate the significance of scavenging a specific oxidant in the prevention of cellular injury and disease states caused by the reactive free radical species.

• Molecules and Cells
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• 제38권7호
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• pp.657-662
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• 2015

Rapid and efficient engulfment of apoptotic cells is an essential property of phagocytes for removal of the large number of apoptotic cells generated in multicellular organisms. To achieve this, phagocytes need to be able to continuously uptake apoptotic cells. It was recently reported that uncoupling protein 2 (Ucp2) promotes engulfment of apoptotic cells by increasing the phagocytic capacity, thereby allowing cells to continuously ingest apoptotic cells. However, the functions of Ucp2, beyond its possible role in dissipating the mitochondrial membrane potential, that contribute to elevation of the phagocytic capacity have not been determined. Here, we report that the anion transfer or nucleotide binding activity of Ucp2, as well as its dissipation of the mitochondrial membrane potential, is necessary for Ucp2-mediated engulfment of apoptotic cells. To study these properties, we generated Ucp2 mutations that affected three different functions of Ucp2, namely, dissipation of the mitochondrial membrane potential, transfer of anions, and binding of purine nucleotides. Mutations of Ucp2 that affected the proton leak did not enhance the engulfment of apoptotic cells. Although anion transfer and nucleotide binding mutations did not affect the mitochondrial membrane potential, they exerted a dominant-negative effect on Ucp2-mediated engulfment. Furthermore, none of our Ucp2 mutations increased the phagocytic capacity. We conclude that dissipation of the proton gradient by Ucp2 is not the only determinant of the phagocytic capacity and that anion transfer or nucleotide binding by Ucp2 is also essential for Ucp2-mediated engulfment of apoptotic cells.

• 한국통신학회논문지
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• 제29권9A호
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• pp.1022-1030
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• 2004

차세대 이동 및 우선통신 시스댐은 현재보나 얘우 큰 고속의 데이터 전송과 시스템 용량을 요구하고 였으며 이러한 요구를 충족시키기 위해서 복수의 안테나를 사용하여 송수신을 하는 MIMO(m 비 tiple input, multiple output) 기술이 널리 연구되고 있다 이 논문은 다수의 안테나를 가지고 있는 기지국, 소수의 안테나를 가지고 있는 단말기의 하향 링크에서 스케터령과 변동이 적으며 평탄한 페이딩 채널을 가정한다. 단영 사용가 MIMO 시스템에서 가지국이 채널상태정보를 가지고 있다연 SVD(singular value decomposition) 와 water filling 읍 사용 한 MIMO 기숭이 최대의 채널용량을 이룬다. 그러나 복수 사용자 시스템의 경우에는 공간분할 다중접속 기술을 이용하여, 보다 큰 전체 채널용량을 얻는 것이 가능하다 이 논문은 복수 사용가 시스템에서 각 사용자에게 복수 의 데이터 스트림을 전송하는 MIMO 공간분할 다중접속 기술을 제안한다. 제안하는 기술은 SVD 기반의 MIMO 기술이나 스마트 안테나를 사용한 공간분항 다중정속 기술보다 더 큰 전체 채널용량을 얻을 수 있다.