• Journal of the Korea Society for Simulation
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• v.10 no.4
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• pp.11-20
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• 2001

In the IMT-2000 networks, the model of micro/pico cell is suggested for transmission of multimedia service. Hence, the efficient method is required for processing of mobile calls in micro/pico cell. In the central urban area, mobile calls may be dynamically increased because of many mobile users. And microcel]/picocell size has small size, handover calls will be more increased. Therefore, many of mobile calls is occurred at a cell in the central urban area, so channel requests for these calls will be increased in the call. In this paper, we propose a scheme, FTC(Fault Tolerant Channel allocation) which is the channel management method for hard handover and new call in a mobile cell of central urban area. When available channels in the cell are consumed, the FTC investigates channel states of neighbor cells in the RNC(Radio Network Controller) or BSC (Base Station Center), and provide available channel for mobile call. The ]no scheme is analyzed and compared with existing channel management method by simulation.

• Journal of Korean Institute of Industrial Engineers
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• v.23 no.3
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• pp.581-595
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• 1997

The procedure of grouping the machines and parts to form cells is called manufacturing cell design. The manufacturing cell design is an important step in the development and implementation of advanced manufacturing systems. For the successful implementation of the manufacturing systems, identification of independent manufacturing cells, i.e., cells where parts are completely processed in the cell and no intercell movements, is necessary in the design phase. In this paper, we developed a mixed integer programming model and genetic algorithm based procedure to solve the independent manufacturing cells design problem considering the alternative process plans and machines duplication. Several manufacturing parameters such as, production volume, machine capacity, processing time, number of cells and cell size, are considered in the process. The model determines the process plan for parts, port families and machine cells simultaneously. The model has been verified with the numerical examples.

• Journal of the Korean Society of Visualization
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• v.21 no.3
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• pp.93-100
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• 2023

The yeast Saccharomyces cerevisiae (S. cerevisiae) is considered an ideal eukaryotic model and has long been recognized for its pivotal role in numerous industrial production processes. Depending on the cell cycle phases, microenvironment, and species, S. cerevisiae varies in shape and has different sizes of each shape such as singlets, doublets, and clusters. Obtaining high-purity populations of uniformly shaped S. cerevisiae cells is crucial in fundamental biological research and industrial operations. In this study, we propose an acoustofluidic method for separating S. cerevisiae cells based on their size using surface acoustic wave (SAW)-induced acoustic radiation force (ARF). The SAW-induced ARF increased with cell diameter, which enabled a successful size-based separation of S. cerevisiae cells using an acoustofluidics device. We anticipate that the proposed acoustofluidics approach for yeast cell separation will provide new opportunities in industrial applications.

• JSTS:Journal of Semiconductor Technology and Science
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• v.14 no.5
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• pp.609-614
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• 2014

The fringe field effects on the transient characteristics of nano-electromechanical (NEM) memory cells have been discussed by using an analytical model. The influence of fringe field becomes stronger as the size of a cell decreases. By using the proposed model, the dependency of NEM memory transient characteristics on cell parameters has been evaluated.

• International Journal of Stem Cells
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• v.17 no.1
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• pp.70-79
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• 2024

The efficacy of adipose-derived stem cells (ASCs) on myocardial infarction is limited due to poor survival and engraftment. Integrin-mediated cell adhesion is a prerequisite for its survival and homing. ASCs expressed insufficient integrin 𝛼₄, limiting their homing capacity. This study aims to characterize integrin 𝛼₄⁺ ASC subpopulation and investigate their therapeutic efficacy in myocardial infarction. We used fluorescence-activated cell sorting to harvest integrin 𝛼₄⁺ ASCs subpopulation, which were characterized in vitro and transplanted into myocardial infarction model. Positron emission tomography imaging were performed to measure infarction size. Cardiac cine magnetic resonance imaging was used to evaluate heart contractile function. Compared with the unfractionated ASCs, integrin 𝛼₄⁺ ASCs subpopulation secreted a higher level of angiogenic growth factors, migrated more rapidly, and exhibited a stronger anti-apoptotic capacity. Vascular cell adhesion molecule-1 was obviously up-regulated at 3 days after myocardial infarction, which interacted with integrin α₄ receptor on the surface of ASCs to enhance the survival and adhesion. Thus, we implanted unfractionated ASCs or integrin α₄⁺ ASCs subpopulation into the 3-day infarcted myocardium. Integrin α₄⁺ ASCs subpopulation exhibited more robust engraftment into the infarcted myocardium. Integrin α₄⁺ ASCs subpopulation more effectively decreased infarct size and strengthen cardiac function recovery than did the unfractionated ASCs. Integrin α₄⁺ ASCs subpopulation is superior to unfractionated ASCs in ameliorating ischemic myocardial damage in animal model. Mechanistically, their more robust engraftment into the infarct area, higher migratory capacity and their increased release of paracrine factors contribute to enhanced tissue repair.

• 한국신재생에너지학회:학술대회논문집
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• 2011.11a
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• pp.86.1-86.1
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• 2011

To improve the safety, the fuel cell operate inside a pressurized enclosure which contains inert gas so called protective gas. The protective gas not only prevents the mixture of hydrogen and oxygen, but also removes the water in the vessel with the condenser. This study presents the details of the flow optimization in order to reduce the humidity in the fuel cell housing. The protective gas flow in the fuel cell container is studied by Computational Fluid Dynamics(CFD) simulations. This study focuses on optimizing the geometry of an protective gas circulation system in fuel cell module to reduce the humidity in the vessel. CFD analysis was carried out for an existing model to understand the flow behavior through the fuel cell system. Based on existing model CFD results, geometrical changes like inlet placement, optimization of outlet size, modification of fuel cell module system are carried out, to improve the flow characteristics. The CFD analysis of the optimized model is again carried out and the results show good improvement in protective gas flow behavior.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.20 no.3
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• pp.197-204
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• 2008

DMFC(Direct Methanol Fuel Cell) is one of promising candidates for power sources of small mobile IT devices like notebook, cell phone, and so on. Efficient operation of fuel cell system is very important for long-sustained power supply because of limited fuel tank size. It is necessary to investigate operation characteristics of fuel cell stack for optimal control of DMFC system. The generated voltage was modeled according to various operating condition; methanol concentration, stack temperature, and load current. It is inevitable for methanol solution at anode to cross over to cathode through MEA(membrane electrode assembly), which reduces the system efficiency and increases fuel consumption. In this study, optimal operation conditions are proposed by analyzing stack performance model, cross-over phenomenon, and system efficiency.

• KSBB Journal
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• v.14 no.5
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• pp.534-538
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• 1999

For the optimization of operating conditions for plant cell suspension culture in bioreactors, effects of bioreactor types, various kinds of impellers, and aeration rates were examined using Nicotiana tabacum cells as a model system. Stirred tank bioreactor and airlift bioreactor were used for the comparison of bioreactor type. Growth rates in both bioreactors were lower than in shake flasks. In terms of final cell concentration, stirred tank bioreactor supported a little bit better growth compared to airlift bioreactor. Impeller type did not affect cell growth significantly, but it was apparent that cell size index decreased in the case of using hollowed paddle impeller. When the aeration rate was maintained at 0.3 vvm, cell growth was the best. At above 1.0 vvm, growth inhibition as well a browning was noticed. In addition, it was found that cell size index reduced proportionally to the increased of aeration rate.

• Journal of Microbiology and Biotechnology
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• v.9 no.3
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• pp.323-327
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• 1999

It was shown that brain-derived neurotrophic factors (BDNFs) secreted from human neuroblastoma cells can significantly improve the growth of the neurites of PC12 nerve cells. The addition of purified BDNFs elongated the neurites of PC 12 nerve cells two to three times more than the case where the addition was not made. The perfusion rate strongly affected the change of the size of human neuroblastoma cells because the cell size decreased as the perfusion rate increased. This could also influence the productivity of BDNF from the cells. It is also important to note that the BDNF production was decreased when the cell size was reduced. BDNF production rate also decreased at a fast perfusion rate in a smaller cell size. At the relatively fast perfusion rate of 18 ml/h, the ratio of apoptotic to necrotic cells dramatically decreased, which possibly caused the decrease of BDNF production. It has been proven that the secretion of BDNF from human neuroblastoma cells was a partially growth-related process by yielding 6.2$\times l0^{-8}/g$ of BDNF/cell/h of growth related parameter and $0.48{\times}l0^{-9}/g$ of BDNF/cell/h of nongrowth-related parameter in a growth kinetic model. In addition, it was also found that the perfusion rate played a very important role in controlling the cell death mechanism.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.5 no.9
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• pp.1596-1612
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• 2011

Coordinated Multi-Point (CoMP) transmission / reception is being studied in Long Term Evolution-Advanced (LTE-A) for future evolution of the $3^{rd}$ Generation Partnership Project (3GPP) LTE. Support of soft handover is essential for improving the performance of cell edge users. CoMP provides a natural framework for enabling soft handover in the LTE system. This paper evaluates the soft handover gain in LTE-A downlink. Mathematical analysis of signal to interference plus noise ratio (SINR) gain and the handover margins for soft handover and hard handover are derived. CoMP system model is developed and an inter-cell and intra-cell interference model is derived, taking into account the pathloss, shadowing, cell loading, and traffic activity. Reference signal received power (RSRP) is used to define the triggers and the measurements for soft handover. Our results indicate that parameter choices such as handover margin and the CoMP set size impact CoMP performance gain.