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Case Reports of Adipose-derived Stem Cell Therapy for Nasal Skin Necrosis after Filler Injection

  • Sung, Ha-Min;Suh, In-Suck;Lee, Hoon-Bum;Tak, Kyoung-Seok;Moon, Kyung-Min;Jung, Min-Su
    • Archives of Plastic Surgery
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    • v.39 no.1
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    • pp.51-54
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    • 2012
  • With the gradual increase of cases using fillers, cases of patients treated by non-medical professionals or inexperienced physicians resulting in complications are also increasing. We herein report 2 patients who experienced acute complications after receiving filler injections and were successfully treated with adipose-derived stem cell (ADSCs) therapy. Case 1 was a 23-year-old female patient who received a filler (Restylane) injection in her forehead, glabella, and nose by a non-medical professional. The day after her injection, inflammation was observed with a $3{\times}3cm$ skin necrosis. Case 2 was a 30-year-old woman who received a filler injection of hyaluronic acid gel (Juvederm) on her nasal dorsum and tip at a private clinic. She developed erythema and swelling in the filler-injected area A solution containing ADSCs harvested from each patient's abdominal subcutaneous tissue was injected into the lesion at the subcutaneous and dermis levels. The wounds healed without additional treatment. With continuous follow-up, both patients experienced only fine linear scars 6 months postoperatively. By using adipose-derived stem cells, we successfully treated the acute complications of skin necrosis after the filler injection, resulting in much less scarring, and more satisfactory results were achieved not only in wound healing, but also in esthetics.

Efficient Application of Multi-Trade Contract Method to Public Construction Project (공공건설사업 직할시공제 적용의 문제점 및 효율적 적용 방안)

  • Chang, Chul-Ki
    • Korean Journal of Construction Engineering and Management
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    • v.14 no.2
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    • pp.35-44
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    • 2013
  • Multi-trade Contract Method was introduced as a means of cutting down construction cost of public housing for low income people. Before a specific project delivery method is applied to large public construction project, it is necessary to discuss all the issues raised up from all the parties in construction industry and all the issues which can impact project performance. Thus the interviews were conducted with industrial professionals from diverse organizations and previous studies were investigated to figure out how this newly introduced project delivery method may impact owner's role and responsibility and project performance in terms of cost, schedule, quality and risk. Under the Multi-trade Contract Method, project owner's management tasks will be highly increased, so it should be checked out if the owner can do its role and responsibility. Public owner's organization also needs to be changed and proper project management procedure and system need to be established. In addition, for efficient application of Multi-trade Contract Method, public owner should consider diverse management approach to deliver the project, and how to select and maintain qualified specialty trades.

Changes in External Radiation Dose Rate for PET-CT Test Patients (PET-CT 검사 환자의 외부 방사선량률 변화)

  • Kim, Su-Jin;Han, Eun-Ok
    • Journal of Radiation Protection and Research
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    • v.37 no.2
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    • pp.103-107
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    • 2012
  • This paper analyzes changes in the external radiation dose rate of PET-CT test patients as a part of providing basic materials for reduction of radiation exposure to PET-CT test patients. In theory the measurement of external radiation dose rate of PET-CT test patients shows that the further the distance from the patient injected with radioactive pharmaceutical and a longer time elapsement from the injection leads to a smaller amount of radiation. Particularly, the amount of radiation marked the highest in the chest was at 4.17 minutes immediately after the intravenous injection and in the head after 77.47 minutes after urination in advance to the PET-CT test. As in the generalized information, it is desired to keep distance between the patient and caretakers or professionals to reduce the amount of radiation exposure from PET-CT test patients and to resume contact the patient after the time when the radiation has reduced. If contact is unavoidable, it is desired to keep at least 200cm from the patient. In addition, the amount of radiation reached the highest in the chest at first and then in the head from 77 minutes after injection. Accordingly, it would be helpful in achieving the optimization if contact is made based on the patient's physical characteristics. This study is significant as it measures changes in radiation the dose rate by; distance from the PET-CT test patient, time elapsed, and specific parts of body. Further studies based on the findings in this paper are required to analyze changes in radiation dose rate in accordance with individual characteristics unique to PET-CT patients and to utilize the results to reduce the amount of radiation patient, caretakers and professions are exposed.

The study of MDCT of Radiation dose in the department of Radiology of general hospitals in the local area (일 지역 종합병원 영상의학과 MDCT선량에 대한 연구)

  • Shin, Jung-Sub
    • Journal of the Korean Society of Radiology
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    • v.6 no.4
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    • pp.281-290
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    • 2012
  • The difference of radiation dose of MDCT due to different protocols between hospitals was analyzed by CTDI, DLP, the number of Slice and the number of DLP/Slice in 30 cases of the head, the abdomen and the chest that have 10 cases each from MDCT examination of the department of diagnostic imaging of three general hospitals in Gyeongsangbuk-do. The difference of image quality, CTDI, DLP, radiation dose in the eye and radiation dose in thyroid was analyzed after both helical scan and normal scan for head CT were performed because a protocol of head CT is relatively simple and head CT is the most frequent case. Head CT was significantly higher in two-thirds of hospitals compared to A hospital that does not exceed a CTDI diagnostic reference level (IAEA 50mGy, Korea 60mGy) (p<0.001). DLP was higher in one-third of hospitals than a diagnostic reference level of IAEA 1,050mGy.cm and Korea 1,000mGy.cm and two-thirds exceeded the recommendation of Korea and those were significantly higher than A hospital that does not exceed a diagnostic reference level (p<0.001). Abdomen CT showed 119mGy that was higher than a diagnostic reference level of IAEA 25mGy and Korea 20mGy in one-third. DLP in all hospitals was higher that Korea recommendation of 700mGy.cm. Among target hospitals, C hospital showed high radiation dose in all tests because MPR and 3D were of great importance due to low pitch and high Tube Curren. To analyze the difference of radiation dose by scan methods, normal scan and helical scan for head CT of the same patient were performed. In the result, CTDI and DLP of helical CT were higher 63.4% and 93.7% than normal scan (p<0.05, p<0.01). However, normal scan of radiation dose in thyroid was higher 87.26% (p<0.01). Beam of helical CT looked like a bell in the deep part and the marginal part so thyroid was exposed with low radiation dose deviated from central beam. In addition, helical scan used Gantry angle perpendicularly and normal scan used it parallel to the orbitomeatal line. Therefore, radiation dose in thyroid decreased in helical scan. However, a protocol in this study showed higher radiation dose than diagnostic reference level of KFDA. To obey the recommendation of KFDA, low Tube Curren and high pitch were demanded. In this study, the difference of image quality between normal scan and helical scan was not significant. Therefore, a standardized protocol of normal scan was generally used and protective gear for thyroid was needed except a special case. We studied a part of CT cases in the local area. Therefore, the result could not represent the entire cases. However, we confirmed that patient's radiation dose in some cases exceeded the recommendation and the deviation between hospitals was observed. To improve this issue, doctors of diagnostic imaging or technologists of radiology should perform CT by the optimized protocol to decrease a level of CT radiation and also reveal radiation dose for the right to know of patients. However, they had little understanding of the situation. Therefore, the effort of relevant agencies with education program for CT radiation dose, release of radiation dose from CT examination and addition of radiation dose control and open CT contents into evaluation for hospital services and certification, and also the effort of health professionals with the best protocol to realize optimized CT examination.

Comparison of Food Intakes and Serum Lipid Levels in Overweight and Obese Women by Body Mass Index (과체중 및 비만여성의 식습관, 식이섭취실태 및 혈청지질 양상 비교)

  • Kim, Ok-Hyun;Jung, Ha-Na;Kim, Jung-Hee
    • Korean Journal of Community Nutrition
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    • v.12 no.1
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    • pp.40-49
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    • 2007
  • This study was done to investigate the health-related habits, dietary intakes and serum lipid levels in overweight and obese women by body mass index(BMI). Subjects were 137 pre-menopausal women aged 19 to 49 years. They were divided by 3 groups, overweight($23{\leqq}BMI<25$), obese($25{\leqq}BMI<30$) and morbidly obese($BMI{\geq}30$) according to their BMI. Body composition was determined by bioelectrical impedance analysis(BIA) method. Dietary intakes were examined by 3-day record method and nutrient intakes were analyzed by the Computer Aided Nutritional analysis program for professionals(CAN-pro 3.1). Serum lipid levels were measured using automatic biochemical analyzer(Selectra E). The average age, height weight and BMI of subjects were 31.7 years old, 159.3cm, 69.4kg, and $27.4kg/m^2$, respectively. Their average consumption of energy were 1712kca1 and 86.4% of estimated energy requirement(EER). Their mom ratio of carbohydrate:protein:fat was 55.2:14.6:30.2. Particularly, the fat consumption of subjects tended to be elevated with increasing BMI. There was no significant difference in nutrient intakes among 3 groups. But the mom intakes of Ca, Fe, vitamin C and Na of all the subjects were 70.1%, 81.2%, 75.7% of recommended intake(RI) and 258.9% of adequate intake(AI), respectively, The intakes of vegetables and seaweeds were significantly higher in morbidly obese group while the intake of fruits was higher in overweight group compared to the other groups. Serum lipid analysis showed that there were no significant differences in the levels of total cholesterol, triglyceride and LDL-cholesterol among the groups. But the serum HDL-cholesterol level of the overweight group was significantly higher than that of the other groups. LDL-/HDL-cholesterol ratio and AI index were significantly higher in the morbidly obese group compared to the other groups. In addition, The systolic blood pressure of morbidly obese group was significantly higher compared to the other groups. Overall data suggest that morbidly obese women have to more concern about reducing systolic blood pressure and nm lipid levels by decreasing their fat consumption and salt intakes as well as loosing body fat. In addition, all the subjects participated in this study have to be careful about their meals and health-related behaviors in order to prevent obesity-related chronic diseases.

THE ASSESSMENT OF NOISE IN THE PEDIATRIC DENTAL CLINICS (소아치과 진료실에서 발생하는 소음 평가)

  • Kwon, Bo-Min;Lee, Ji-Hyun;Kim, Shin;Jeong, Tae-Sung
    • Journal of the korean academy of Pediatric Dentistry
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    • v.39 no.3
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    • pp.267-272
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    • 2012
  • Dental professionals are exposed to various occupational risks, among which the problem of hearing damage has been newly revealed. There have been some researches reporting that noise occurring in a dental office exceeds the Occupational Safety and Health Act (OSHA) Standards. Especially, the pediatric dentists are repeatedly exposed to an additional noise source called the crying sound of children in addition to all kinds of noises from dental instruments. Accordingly, this study intended to investigate the noise environment likely to affect pediatric dentists and to examine the possibility of resultant hearing damages. The level of noise was measured respectively, when various dental instruments (ultrasonic scaler, high-speed handpiece, low-speed handpiece) are operated, when children are crying, and when both occasions take place simultaneously (from the distance of 30 cm) with a portable noise meter. And the daily duration of pediatric dentists exposed to the noise environment was surveyed. The results were compared with the standard value of noise threshold of NIOSH, OSHA, and that of hearing damage of CRA News letter respectively. Considering the intensity and exposure time, the noise environment of pediatric dentists exceeds the allowable noise threshold values. Even only one exposure to crying child was likely to lead to permanent hearing damage. Comparatively, pediatric dentists have a higher risk for occupational hearing damages, and some active measures are thought highly desirable to minimize it.

The Effect of PMIS Quality on Project Management Success (PMIS의 품질이 프로젝트관리의 성공에 미치는 영향 분석)

  • Lee, Seul-Ki;Lee, Hyoung-Lak;Yu, Jung-Ho
    • Journal of the Korea Institute of Building Construction
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    • v.10 no.6
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    • pp.117-126
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    • 2010
  • As one of the key IT applications, the project management information system (PMIS) has played a significant role in construction management processes. This is because PMIS is an information system that gathers, integrates, and disseminates the output of project management processes among project participants, and is used to support all aspects of a project, from initiation through closing. This paper aims to identify the CSFs(Critical Success Factor) of Project Management and quality associated with Project Management Information System (PMIS) in construction projects, to analyze the Effect of PMIS quality on Project Management Success. The CSFs of Project Management and the quality components for PMIS are identified through a review of the literature, and consolidated through interviews with professionals in the construction industry. A questionnaire instrument was sent out to experienced users (Construction Manager and Constructor), and 253 completed questionnaires were retrieved. To increase the applicability of the results, the respondents consisted of workers spread across various parts of the construction site. Using SPSS 12.0, the data was used to analyze the relationship between PMIS Quality and Project Management Success through multiple regression analysis. These findings help to clarify what the highly prioritized factors are, and could also be used as an assessment tool to evaluate the performance of PMIS and thus help to identify areas for improvement.

Carbon Emission Study of Transplanting Large Trees from Gangwon Province to Seoul (강원지역 대형 조경수 서울 이식에 따른 탄소 배출 연구)

  • Choi, Yoo;Ahn, Tong-Mahn;Lee, Jae-Won
    • Journal of the Korean Institute of Landscape Architecture
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    • v.41 no.4
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    • pp.10-16
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    • 2013
  • Korean housing developers are in a very competitive market and their way of attracting buyers is landscaping better than competing firms do. Thus, transplanting larger pine trees(Pinus densiflora S. et. Z.) is in vogue. A typical case is a pine tree about 30-year old, 35 diameters at breast height, transplanted 223 km afar from the Gangwon Province to Seoul. We estimated and compared carbon emissions during the whole transplanting works, and carbon intake by the tree if it survives 50 more years on site. Findings are; first, a large tree will take up and sequestrate approximately 90 kgC if it survives 50 more years. Second, transplanting works emit approximately 113.69 kgC, which is about 1.26 times of its possible future intake of carbon. Landscaping is a legal requirement for the purposes not only of aesthetics but also of environmental quality. Transplanting larger trees that came from a dam or a road building site may be inevitable and acceptable. However, transplanting larger trees long distance was evaluated to be harmful to the environment. It is strongly recommended to prohibit transplanting large trees. Landscape professionals need to guide clients to have desirable consumer attitude.

Diversity, Spatial Distribution and Ecological Characteristics of Relict Forest Trees in South Korea (한국 산림유존목의 다양성, 공간 분포 및 생태 특성)

  • CHO, Hyun-Je;Lee, Cheol-Ho;Shin, Joon-Hwan;Bae, Kwan-Ho;Cho, Yong-Chan;Kim, Jun-Soo
    • Journal of Korean Society of Forest Science
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    • v.105 no.4
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    • pp.401-413
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    • 2016
  • Forest resources utilization and variable disturbance history have been affected the rarity and conservation value of forest relict trees, which served as habitat for forest biodiversity, important carbon stock and cultural role include human and natural history in South Korea. This study was conducted to establish the baseline data for forest resources conservation by clarifying species diversity, spatial distribution and ecological characteristics (individual and habitat) of forest relict trees (DBH > 300 cm) based on the data getting from mountain trail, high resolution aerial photos and field professionals and field survey. As results, 54 taxa (18 family 32 genus 48 species 1 subspecies 3 variety and 2 form) as about 22% of tree species in Korea was identified in the field. 837 individuals of forest relict trees were observed and the majority of the trees was in Pinaceae, deciduous Fagaceae and Rosaceae, which families are abundant in population diversity. High elevation area was important to relict trees as mean altitudinal distribution was 1,200 m a.s.l as likely affected by human activity gradients and mid-steep slope and North aspect was important environment for the trees remain. Many individuals exhibited 'damage larger branch' (55.6%) and consequent relatively lower mean canopy coverages (below 80%). Synthetically, present diversity and abundance of relict forest trees in South Korea were the result of complex process among climate variation, local weather and biological factors and the trees of big and old were estimated to important forest biodiversity elements. In the future, clarifying the role and function of relict trees in forest ecosystem, in- and ex- situ programmes for important trees and habitat, and activities for building the background of conservation policy such as "Guideline for identifying and measurement of forest relict trees".

Evaluation of Grassland Grade by Grassland Vegetation Ratio (초지식생비율에 의한 초지등급평가 연구)

  • Lee, Bae Hun;Kim, Ji Yung;Park, Hyung Soo;Sung, Kyung Il;Kim, Byong Wan
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.40 no.1
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    • pp.29-36
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    • 2020
  • This study was conducted to suggest the new grassland grade system on evaluating the grassland status. The grassland status has been evaluated based on the forage yield (good, fair and poor) by municipal authorities. The grassland grades by current system were 19 good, 11 fair and 11 poor among the 41 grassland farms from 6 provinces. This evaluation result differed greatly from the result of actual measurement of forage yields which showed all poor. The big difference was resulted from failing the reflection of the various characteristics, such as different seasonal growth and harvest frequency. Furthermore, the lack of consistent examining date and method added the inaccuracy of current grassland grade system. The new grassland grade system based on the grassland vegetation ratio (grass, weed and bare soil) was initially designed into 6-grade system (1st; 100~80%, 2nd; 79~60%, 3rd; 59~40%, 4th; 39~20%; 5th; 19~1% and 6th; 0% on the basis of grasses proportion), but later was changed into 4-grade system (1st, 2nd, 3rd, and 4th grades are 70% or more, 50% or more, 50% or less, and 0% of forage proportion, respectively) after reflecting the opinion of grassland farms and municipal authorities. Re-evaluation on the grassland status using the 4-grade system resulted in the total 80% consisted of 2nd, 3rd and 4th grade which means most grasslands needs the partial reseeding or the rehabilitation of entire grassland. Pictures and schematic diagrams depicting the 4-grade system were presented to improve the objectivity of evaluation. The optimal time for assessing grassland status is fall when plant height 20~30 cm. Conclusively, the 4-grade system is an efficient method for all non-professionals including grassland farms or municipal authorities in assessing the grassland status. To apply this system to the field, the institutional arrangements such as amendment of grassland act should take place in advance.