• Title/Summary/Keyword: Boost Factor

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Extracellular Signal-Regulated Kinase Is a Major Enzyme in Korean Mistletoe Lectin-Mediated Regulation of Macrophage Functions

  • Byeon, Se-Eun;Lee, Jae-Hwi;Yu, Tao;Kwon, Moo-Sik;Hong, Sung-Youl;Cho, Jae-Youl
    • Biomolecules & Therapeutics
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    • v.17 no.3
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    • pp.293-298
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    • 2009
  • Korean mistletoe lectin (KML) is the major component found in Viscum album var. (coloratum), displaying anti-cancer and immunostimulating activities. Even though it has been shown to boost host immune defense mechanisms, the regulatory roles of KML on the functional activation of macrophages have not been fully elucidated. In this study, regulatory mechanism of KML on macrophage-mediated immune responses was examined in terms of KML-mediated signaling event. KML clearly induced mRNA expression of tumor necrosis factor (TNF)-$\alpha$, the generation of reactive oxygen species (ROS) and phagocytic uptake in RAW264.7 cells. All of these events were strongly suppressed by U0126, whereas TNF-$\alpha$ mRNA was not diminished by SB203580 and SP600125, indicating ERK as a central enzyme managing KML-induced up-regulation of macrophage functions. Indeed, KML strongly induced the phosphorylation of ERK in a time-dependent manner without altering its total level. Therefore, these data suggest that ERK may be a major signaling enzyme with regulatory property toward various KML-mediated macrophage responses.

Development of High-Speed Elevator Drive System using Permanent-magnet Synchronous Motor (영구 자석형 동기 전동기를 이용한 고속 엘리베이터 구동 시스템 개발)

  • 류형민;김성준;설승기;권태석;김기수;심영석;석기룡
    • The Transactions of the Korean Institute of Power Electronics
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    • v.6 no.6
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    • pp.538-545
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    • 2001
  • In this paper a gearless drive system using a permanent-maget synchronous motor for high speed elevators is addressed. The application of permanent magnet synchronous motor to an elevator traction machine enables several improvements including higher efficiency better ride comfort smaller size and lighter weight and so on A PWM boost converter has been also adopted so that DC-link voltage regulation bi-directional power flow and controllable power factor with reduced input current harmonics are possible. To increase the reliability and performance of overall control system the unified control board which can include the car and group controller as well as PWN converter/inverter controller has been designed based on a DSP TMS320VV33. In addition the dynamic load simulator system has been developed so that the drive system of high speed elevator can be tested and evaluated without and limitation on ride distance. Some experimental results are given to verify the effectiveness of the developed system.

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The effects of Dessert Cafe Franchise's Experiential value on Lovemarks and Brand loyalty: Focusing on the Control Variables by Structural Equation Model

  • Kim, Ki-Soo;Kim, Sung-Hun;Cho, Sung-Ho
    • Journal of Distribution Science
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    • v.16 no.10
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    • pp.39-46
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    • 2018
  • Purpose - this research is to examine the relationship between Franchise's experiential value, lovemarks, respectful recognition, and brand loyalty focusing on the control variables. Control variables such as age, occupation, education, monthly income, and kinds of restaurant are included to measure influence on these as well. Research, design, data, and methodology - 500 questionnaires were distributed from June 10th to July 10th, 2017. 225 respondents were totally included in this analysis using SPSS and AMOS program. In order to test hypothesis, factor analysis and reliability verification firstly were employed, and then covariance structure analysis was used. Results - Empirical results are as followed. First, it can be mentioned that the esthetics of dessert cafe is analyzed to have a positive effect on the perception of love and respectful perception. Second, playfulness has a positive effect on perception of love. Third, respect perception has a positive effect on brand loyalty. When variables such as age, occupation, education, monthly income, and restaurant type were used as control variables, only monthly income had a significant effect on respect recognition. This shows that the control variable has a significant effect on the causal relationship of the variables. Conclusions - In summary, it can be stated that it is necessary for marketers to establish marketing strategies in order to boost customers' experiential value such as esthetics of franchise and also to strengthen lovemarks for respectful recognition and brand loyalty.

Hypofractionated radiotherapy for early glottic cancer: a retrospective interim analysis of a single institution

  • Lee, Jeong Won;Lee, Jeong Eun;Park, Junhee;Sohn, Jin Ho;Ahn, Dongbin
    • Radiation Oncology Journal
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    • v.37 no.2
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    • pp.82-90
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    • 2019
  • Purpose: To evaluate the results of hypofractionated radiotherapy (HFX) for early glottic cancer. Materials and Methods: Eighty-five patients with cT1-2N0M0 squamous cell carcinoma of the glottis who had undergone HFX, performed using intensity-modulated radiotherapy (IMRT, n = 66) and three-dimensional conformal radiotherapy (3D CRT, n = 19) were analyzed. For all patients, radiotherapy was administered at 60.75 Gy in 27 fractions. Forty-three patients received a simultaneous integrated boost (SIB) of 2.3-2.5 Gy per tumor fraction. Results: The median follow-up duration was 29.9 months (range, 5.5 to 76.5 months). All patients achieved complete remission at a median of 50 days after the end of radiotherapy (range, 14 to 206 days). The 5-year rates for locoregional recurrence-free survival was 88.1%, and the 5-year overall survival rate was 86.2%. T2 stage was a prognostic factor for locoregional recurrence-free survival after radiotherapy (p = 0.002). SIB for the tumor did not affect disease control and survival (p = 0.191 and p = 0.387, respectively). No patients experienced acute or chronic toxicities of ≥grade 3. IMRT significantly decreased the dose administered to the carotid artery as opposed to 3D CRT (V35, p < 0.001; V50, p < 0.001). Conclusions: Patients treated with HFX achieved acceptable locoregional disease control rates and overall survival rates compared with previous HFX studies. A fraction size of 2.25 Gy provided good disease control regardless of SIB administration.

Study of university students' perceptions on participation in elections via structural equation model - Focusing on K university students (구조방정식모형을 이용한 대학생의 선거 참여 인식 연구 - K대 학생의 예)

  • Choi, Hyun Seok;Kwon, Yunji;Ha, Jeongcheol
    • Journal of the Korean Data and Information Science Society
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    • v.24 no.2
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    • pp.379-390
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    • 2013
  • Through the survey of the K university students' perception on participation in elections, we want to find ways to induce a sound political participation and to effectively be able to boost voter turnout. We analyze the relations among image on election, interest in election and will of participation via structural equation model. We found that both image on election and interest in election significantly influence on will of participation in election. Using the last election participation as a moderating variable, we found that image on election has more effects on will of participation for the participants but not for the case of interest in election.

Determinants of the China's Antidumping Measure against Japan's products (중국의 일본산 제품에 대한 반덤핑 조치에 영향을 미치는 결정요인)

  • Choi, Chang-Hwan
    • International Commerce and Information Review
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    • v.14 no.1
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    • pp.3-22
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    • 2012
  • China has used the Antidumping policy as a trade protection tool against Japanese products due to reduce the deficit of trade balance of payment, boost the economic growth and protect its weak industries. This paper investigates whether there is a connection between the China's macroeconomic activity and pressures for protection to Japanese products under antidumping measures with using the current data that come from the WTO, World Bank for 1997 to 2010. The result suggests that pressures for protection under Antidumping measure against exporting of Japanese products to China have increased during periods of macroeconomic weakness like high unemployment, larger deficit of trade balance and decreased during periods of macroeconomic strength.

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Methods of Eco-jewelry Design Using regeneration possibility Materials (재생가능용품을 사용한 에코장신구디자인 방안 모색)

  • Kim, Dong-Hyun;Choi, Yun-Jeung
    • The Journal of the Korea Contents Association
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    • v.12 no.12
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    • pp.103-110
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    • 2012
  • Various industrial sectors have formally turned to Green Development, practicing eco-design with the goal of saving the environment. Such trend can also be applied to jewelry design and production. Jewelry, which emerged with the birth of humankind, has been a contributing factor to environmental pollution and depletion of resources due to mass production and reckless consuming patterns of the 20th century. With the arrival of the World economic crises, however, the consumption of jewelry has dropped and now the industry desperately needs a boost for revival. In this paper, we propose a way to recycle waste materials and turn them into a new kind of jewelry. We introduce various junk materials that can be reused, and how to reuse them. The new type of jewelry we aim for is environment-friendly, low-cost, and unique as opposed to identical mass production of the past. The eco-design product will likely add new value to jewelry industry. The product targets sophisticated modern consumers with conscientious, environmentally aware consuming patterns. To fulfill the needs of these consumers, we propose methods of upcycling from junk to jewelry, by combining precious stones with waste materials.

An Insight of Meat Industry in Pakistan with Special Reference to Halal Meat: A Comprehensive Review

  • Sohaib, Muhammad;Jamil, Faraz
    • Food Science of Animal Resources
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    • v.37 no.3
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    • pp.329-341
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    • 2017
  • Livestock is considered central component in agricultural sector of Pakistan, provides employment to more than 8 million families. Meat and meat products holds pivotal significance in meeting dietary requirements serving as major protein source and provide essential vitamins and minerals. Globally, consumer demand is increasing for healthy, hygienic and safe meat and meat products due to growing population, income level and food choices. As, food choices are mainly influenced by region, religion and economic level. However, religion is one of the major factor to influence the food choices. In this context, halal foods a growing trend, trade estimated to cross USD $ 3 trillion and among this, meat sector contribute about US$ 600 billion. Halal meat and allied products is requirement from Muslims but it is also accepted by non-Muslims due to safe and hygienic nature, nutritious value and superior quality. Pakistan meat industry is vibrant and has seen rigorous developments during last decade as government also showed interest to boost livestock production and processing facilities to meet increasing local and global demand. The industry has potential to grow owing to its natural animal rearing capability, muslim majority country (96% of total population), improvisation of market and consumer preference towards halal meat. Current review debates Pakistan meat industry scenario, production trend, global trade as well as future potential with respect to modernization, processing, distribution and trade. The data presented here is useful for meat producers, processors and people involved in export of Pakistani meat and meat based products.

Effects of National Pride and National Attachment on Consumer Ethnocentrism (국가 자부심, 국가 애착이 소비자 자민족주의에 미치는 영향)

  • Choy, Jung-Hyuck;Choi, Soon-Hwa
    • Journal of Distribution Science
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    • v.14 no.12
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    • pp.89-97
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    • 2016
  • Purpose - In the major global markets, such as US and China, consumer ethnocentrism has been strengtened and there is a growing need for related study. This research aims to investigate the effects of national pride and national attachment on consumer ethnocentrism, using a nationally representative dataset from 2013 Korean General Social Survey. Based on the reviews of literature in social and political sciences, two dimensions of national pride were considered: national society pride which is based on positive evaluations on the nation's democracy condition or social security system, and national achievement pride which is based on positive evaluations regarding the country's achievements in the areas of technology, art, sports, and so on. Research design, data, and methodology - The authors developed a structural model in which two types of national pride, national society and achievement pride, are proposed to affect national attachment, thus influencing consumer ethnocentrism. 1,294 surveys were used for empirical analysis. The hypotheses were tested by utilizing SPSS 22.0 and AMOS 21.0. The unidimensionality of each construct and the nomological validity were supported from the results of factor analyses and correlation analysis. Results - It was found that both national society pride and national achievement pride have significant and positive effects on national attachment. Consumers who show stronger pride on the social systems or the global achievements of Korea are more likely to remain being a citizen of the country and support the country even in wrong. Also, there was a significant and positive relationship between national attachment and consumer ethnocentrism. Korean consumers who have stronger attachment to Korea tend to express higher ethnocentrism to protect Korean labor market and to promote economic development of the country. Conclusions - The findings of this study showed that companies and government need to emphasize the country's advanced social environments or global competitiveness in technology, sports, art, and so on, to boost national attachment. With a deeper understanding on the relationships among national pride, national attachment, and consumer ethnocentrism, the authors expect that both local and foreign companies in Korea will be able to develop more effective marketing strategies and to achieve sustainable competitive advantage.

Intertextuality of Materials in the Contemporary Fashion (현대패션에 나타난 소재 상호텍스트성)

  • Kim, Sun-Young;Shim, Joon-Young
    • Journal of the Korean Society of Clothing and Textiles
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    • v.32 no.5
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    • pp.741-752
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    • 2008
  • The purposes of this study are to review the status of dress material in the contemporary fashion design by examining the intertextuality of many materials other than textiles used in the contemporary fashion and to show that the development of new fashion materials is a factor for designing competitiveness. The results of this study are summarized as follows: First, foods and natural objects are used as fashion materials to reveal natural beauty, and at the same time new formative elements are expressed in combinations of life and fashion. Second, common paper and luxurious jewelry are presented as a formative element symbolic of an aspect of the contemporary society or embodied in elaborate handicraft techniques. Those materials boost the luxuriousness of costume and create a strong futuristic image according to how they are expressed. Third, plastics available for a variety of objects in different shapes and colors offer such formative features that could be shaped with textiles, as high-end technology is introduced to fashion. Fourth, metallic materials have added freedom to design formality due to their qualities of convergence and displacement and by the introduction of brand-new technology, suggesting a new future for the fashion industry. Fifth, using a variety of anti-fashion materials including semiconductor chips, mirrors, vinyl, wires, and rubber makes a change in the existing points of view regarding the formality of things and helps create a special aesthetic effect in a visual respect to develop a strong intertextuality of materials.