• Archives of Pharmacal Research
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• 제26권2호
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• pp.157-161
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• 2003

The major ingredient of Persicae Semen is a cynogenic compound, amygdalin (D-mandelonitrile-$\beta$-gentiobioside). Controversial results on the anticancer activity of amygdalin were reported due to its conversion to its inactive isomer, neoamygdalin. In order to inhibit the epimerization of amygdalin, we used newly developed simple acid boiling method in preparation of Persicae Semen extract. HPLC analysis revealed most of amygdalin in Persicae Semen extract was active D-form. Persicae Semen extract was used to analyze its effect on cell proliferation and induction of apoptosis in human promyelocytic leukemia (HL-60) cells. Persicae Semen extract was cytotoxic to HL-60 cells with $IC_{50}$ of 6.4 mg/mL in the presence of 250 nM of $\beta$-glucosidase. The antiproliferative effects of Persicae Semen extract appear to be attributable to its induction of apoptotic cell death, as Persicae Semen extract induced nuclear morphology changes and internucleosomal DNA fragmentation.

• 약학회지
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• 제55권1호
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• pp.45-48
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• 2011

Traditional medicines usually use combinational formula that are prepared by mixing different varieties of medicinal herbs and boiling them in water to yield a decoction. In recent years a modified method has been proposed and practiced wherein the individual herbs are boiled with water separately and later these extracts are mixed together for use. We attempted to evaluate their equivalence in terms of its polyphenol contents and DPPH radical scavenging activity. The polyphenol contents as well as the DPPH radical scavenging activities were very similar to each other.

• Nuclear Engineering and Technology
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• 제41권7호
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• pp.929-944
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• 2009

The present study is concerned with the extension of the Effective Convectivity Model (ECM) to the phase-change problem to simulate the dynamics of the melt pool formation in a Light Water Reactor (LWR) lower plenum during hypothetical severe accident progression. The ECM uses heat transfer characteristic velocities to describe turbulent natural convection of a melt pool. The simple approach of the ECM method allows implementing different models of the characteristic velocity in a mushy zone for non-eutectic mixtures. The Phase-change ECM (PECM) was examined using three models of the characteristic velocities in a mushy zone and its performance was compared. The PECM was validated using a dual-tier approach, namely validations against existing experimental data (the SIMECO experiment) and validations against results obtained from Computational Fluid Dynamics (CFD) simulations. The results predicted by the PECM implementing the linear dependency of mushy-zone characteristic velocity on fluid fraction are well agreed with the experimental correlation and CFD simulation results. The PECM was applied to simulation of melt pool formation heat transfer in a Pressurized Water Reactor (PWR) and Boiling Water Reactor (BWR) lower plenum. The study suggests that the PECM is an adequate and effective tool to compute the dynamics of core melt pool formation.

• 한국막학회:학술대회논문집
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• 한국막학회 1998년도 춘계 총회 및 학술발표회
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• pp.89-92
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• 1998

1. Introduction : Among many azeotropic compounds, pyridine which forms an azeotropic mixture with three moles of water boiling at 92-93$\circ$C is very useful synthetic intermediate in laboratory and industry. With conventional separation method, the dehydration of pyridine aqueous solution is difficult and requires strong drying chemicals. To overcome these difficulties, several researchers have investigated on the separation of pyridine from aqueous solution through polymer membranes. Kujawski reported several ion-exchang membranes containing carboxylic and sulfonic fuctional group for dehydration of aqueous pyridine solution [1]. We have applied the idea of activation of water tranport through ion-dipole interactions between polymer membrane and aclueous feed. Our previous studies reported on the in-situ complex membrane to separate water from aqueous pyridine solution based on simple acid'-base theory [2, 3]. Water transport was enhanced through in-situ complex formation between the , acid moiety in the membrane and the incoming pyridine moiety in the feed.

• 한국압력기기공학회 논문집
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• 제7권3호
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• pp.8-14
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• 2011

The clogging of the flow area at the tube support plates(TSPs), especially at the upper TSPs results in the water level oscillation of a steam generator during normal operation. A reduction of the TSP flow area causes to increase in pressure drop within the two-phase flow zone, which destabilizes the boiling flow through the tube bundle. This phenomenon was occasionally observed at a few domestic and foreign nuclear power plants. One of the methods for defining the flow area clogging is visual inspection, which is the most effective inspection method. The results of the visual inspection for TSPs' flow area are clogging images on TSPs' quartrefoil lobes. These images are complexly distorted due to lens aberration and external factors like the distance to a subject and angle etc. In this work, we developed the analysis algorithm for clogging image of the TSP flow area of steam generators. For this purpose, we designed an image verification device applicable to the camera employed in the field for visual inspection and then, we demonstrated the validity of image analysis algorithm by using this device and commercial autoCAD program.

• Journal of Advanced Marine Engineering and Technology
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• 제10권1호
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• pp.74-84
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• 1986

Ejectors, having no moving, lubricating and leaking parats, are widely used as marine pumps because of its high working confidence. For instance, uses in ships are stripping in crude oil tank, bilge discharge in engine room, ballast water pumping on are carrier, and brine discharge from fresh water generator. And it is also used as cooling water recirculating pump in boiling water type nuclear reactor and deep-well pump. It is not easy to determine the optimal dimension for designing each ejector agreed with its suggested performance condition, because complicated calculations must be repeated to obtain the maximum efficiency affected by flowrate ratio, head ratio, area ratio and so on. Therefore, it is considered that the CAD (Computer-Aided Design) for ejector is a powerful method for design according to the individual design condition. In this paper, a computer program for water ejector design is developed based on the previous paper on theoretical analysis and experimental results for water ejector. And from the theoretical approach, an equation for the working limit and an equation for determing the shape of throat are obtained. The validity of the present computer program is sufficiently confirmed through the comparison of the computed results with the main dimension of the previous manufactured water ejector. This program will be easily developed as the CAD for various kinds of ejectors, including steam ejector.

• 대한기계학회논문집B
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• 제33권1호
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• pp.17-27
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• 2009

Water jet impingement cooling is used to remove heat from high-temperature surfaces such as hot steel plates in the steel manufacturing process (thermo-mechanical cooling process; TMCP). In those processes, uniform cooling is the most critical factor to ensure high strength steel and good quality. In this study, experiments are performed to measure the heat transfer coefficient together with the inverse heat conduction problem (IHCP) analysis for a plate cooled by planar water jet. In the inverse heat transfer analysis, spatial and temporal variations of heat transfer coefficient, with no information regarding its functional form, are determined by employing the conjugate gradient method with an adjoint problem. To estimate the two dimensional distribution of heat transfer coefficient and heat flux for planar waterjet cooling, eight thermo-couple are installed inside the plate. The results show that heat transfer coefficient is approximately uniform in the span-wise direction in the early stage of cooling. In the later stage where the forced-convection effect is important, the heat transfer coefficient becomes larger in the edge region. The surface temperature vs. heat flux characteristics are also investigated for the entire boiling regimes. In addition, the heat transfer rate for the two different plate geometries are compared at the same Reynolds number.

• Nuclear Engineering and Technology
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• 제49권4호
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• pp.663-667
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• 2017

Delayed hydride cracking (DHC) was first observed in pressure tubes in Canadian CANDU reactors. In light water reactors, DHC was not observed until the late 1990s in high-burnup boiling water reactor (BWR) fuel cladding. In recent years, the focus on DHC has resurfaced in light of the increased interest in the cladding integrity during interim conditions. In principle, all spent fuel in the wet pools has sufficient hydrogen content for DHC to operate below $300^{\circ}C$. It is therefore of importance to establish the critical parameters for DHC to operate. This work studies the threshold stress intensity factor ($K_{IH}$) to initiate DHC as a function of temperature in Zry-4 for temperatures between $227^{\circ}C$ and $315^{\circ}C$. The experimental technique used in this study was the pin-loading testing technique. To determine the $K_{IH}$, an unloading method was used where the load was successively reduced in a stepwise manner until no cracking was observed during 24 hours. The results showed that there was moderate temperature behavior at lower temperatures. Around $300^{\circ}C$, there was a sharp increase in $K_{IH}$ indicating the upper temperature limit for DHC. The value for $K_{IH}$ at $227^{\circ}C$ was determined to be $2.6{\pm}0.3MPa$ ${\surd}$m.

• 대한가정학회지
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• 제47권8호
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• pp.109-117
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• 2009

This study was conducted to investigate the uses of Aster scaber. The survey methodology employed was a questionnaire, which was used to interview 272 (37.8%) males and 448(62.2%) females from the Seoul and Kyunggido areas. The main results are as follows: 40-50 years old like and eat Aster scaber more frequently than 10-30 years old. The most popular reason provided for the preferance of Aster scaber was good health benefits. People indicating a dislike for Aster scaber had generally fewer previous experiences of eating this plant. Respondents who regularly ate healthy foods preferred prepared Aster scaber to others foods(p < .001). The main purchasing place was traditional markets and supermarkets. The main cooking method was boiling with addition of seasoning. Aster scaber was purported as having the following characteristics "low calories and thus great as diet food'(4.03), 'ability to prevent adult disease'(3.95), 'high in vitamins and minerals'(3.89), and 'high fiber content which prevented constipation'(3.85). However, it was not associated with 'astringent taste'(3.51) and was regarded as 'fat accumulation restrainer and remover of heavy metal'(3.53). Recognition and eating experience was low for Aster scaber kimchi and rice bread, bread, sauce and Aster scaber added health drinks. However opinion of its taste was regarded highly.

• International Journal of Ocean System Engineering
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• 제1권1호
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• pp.46-51
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• 2011

In a line heating process for hull forming, the phase of the steel transforms from austenite to martensite, bainite, ferrite, or pearlite depending on the actual speed of cooling following line heating. In order to simulate the water cooling process widely used in shipyards, a heat transfer analysis on the effects of impinging water jet, film boiling, and radiation was performed. From the above simulation it was possible to obtain the actual speed of cooling and volume percentage of each phase in the inherent strain region of a line heated steel plate. Based on the material properties calculated from the volume percentage of each phase, it should be possible to predict the plate deformations due to line heating with better precision. Compared to the line heating experimental results, the simulated water cooling process method was verified to improve the predictability of the plate deformation due to line heating.