YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Equivalence of Mixed and Individual Preparation of Galgeun-tang in terms of Polyphenol Contents and DPPH Radical Scavenging Activity

폴리페놀 및 DPPH 라디칼 소거활성 관점에서의 복합갈근탕 및 단미혼합갈근탕의 동등성

  • Kim, Dong-Seon (Herbal Medicine Improvement Research Center, Korea Institute of Oriental Medicine) ;
  • Um, Young-Ran (Herbal Medicine Improvement Research Center, Korea Institute of Oriental Medicine) ;
  • Yang, Min-Chul (Herbal Medicine Improvement Research Center, Korea Institute of Oriental Medicine) ;
  • Yun, Na-Young (Herbal Medicine Improvement Research Center, Korea Institute of Oriental Medicine) ;
  • Jung, Sang-Won (Herbal Medicine Improvement Research Center, Korea Institute of Oriental Medicine) ;
  • Lee, Jae-Hoon (Herbal Medicine Improvement Research Center, Korea Institute of Oriental Medicine) ;
  • Ma, Jin-Yeul (Herbal Medicine Improvement Research Center, Korea Institute of Oriental Medicine)
  • 김동선 (한국한의학연구원 신한방제제연구센터) ;
  • 엄영란 (한국한의학연구원 신한방제제연구센터) ;
  • 양민철 (한국한의학연구원 신한방제제연구센터) ;
  • 윤나영 (한국한의학연구원 신한방제제연구센터) ;
  • 정상원 (한국한의학연구원 신한방제제연구센터) ;
  • 이재훈 (한국한의학연구원 신한방제제연구센터) ;
  • 마진열 (한국한의학연구원 신한방제제연구센터)
  • Received : 2010.10.13
  • Accepted : 2010.12.20
  • Published : 2011.02.28
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Abstract

Traditional medicines usually use combinational formula that are prepared by mixing different varieties of medicinal herbs and boiling them in water to yield a decoction. In recent years a modified method has been proposed and practiced wherein the individual herbs are boiled with water separately and later these extracts are mixed together for use. We attempted to evaluate their equivalence in terms of its polyphenol contents and DPPH radical scavenging activity. The polyphenol contents as well as the DPPH radical scavenging activities were very similar to each other.

Keywords

References

  1. Kwon, C. H. : Effect of Gal Geun Tang upon stress resistance of rat. Kor. J. Pharmacog. 5, 217 (1974).
  2. Chai, I. S. : Sang Han Ron Yeok Jeong. Gomoonsa, Seoul p. 329 (2000).
  3. Chang, Q, Sun, L., Zhao, R. H, Chow, M. S. and Zuo, Z. : Simultaneous determination of ten active components in traditional chinese medicinal products containing both Gegen (Pueraria lobata) and Danshen (Salvia miltiorrhiza) by highperformance liquid chromatography. Phytochem. 19, 368 (2008). https://doi.org/10.1002/pca.1063
  4. Lee, H. O., Kim, C. H., Lim, J. A., Lee, M. H. and Baek, S. W. : Antimicrobial effect of Puerariae thunbergiana extracts against oral microorganism. Korean Soc. of Dental Hygiene Sci. 4, 45 (2004).
  5. Park, C. H., Lim, S. S. and Lee, D. U. : Structure-activity relationships of components from the roots of Pueraria thunbergiana having aldose reductase inhibitory and antioxidative activity. Bull. Korean Chem. Soc. 28, 493 (2007). https://doi.org/10.5012/bkcs.2007.28.3.493
  6. Kim, M. J., Lee, J. S., Ha, O. M., Jang, J. Y. and Cho, S. Y. : Effects of Pueraria thunbergiana (bentham) water extracts on hepatic alcohol metabolic enzyme system in rats. J. Korean Soc. Food Sci. Nutr. 31, 92 (2002). https://doi.org/10.3746/jkfn.2002.31.1.092
  7. 안창균 : 상용한방해설집, 기화제약주식회사, 진주 p. 420 (1999).
  8. Lee, S. O., Lee, H. J., Yu, M. H., Im, H. G. and Lee, I, S. : Total polyphenol contents and antioxidant acivities of methanol extracts from vegetables produced in Ullung island. Korean J. Food Sci. Technol. 37, 233 (2005).
  9. Blois, M. S. : Antioxidant determinations by the use of a stable free radical. Nature. 181, 1199 (1958). https://doi.org/10.1038/1811199a0
  10. Middleton, E., Kandaswami, C. and Theoharides, T. C. : The effects of plant flavonoids on mammalian cells: implications for inflammation heart disease and cancer. Pharmacol. Rev. 52, 673 (2000).